Transcriptional regulation of the MDR1 gene by histone acetyltransferase and deacetylase is mediated by NF-Y

Molecular and Cellular Biology

Volumn 18, Issue 7, 1998, Pages 4377-4384

  Jin, Shengkan ^a   Scotto, Kathleen W ^a,b  

^a Weill Cornell Medical Center   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLYCOPROTEIN P; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; LUCIFERASE; MESSENGER RNA; TRANSCRIPTION FACTOR; TRICHOSTATIN A;

ARTICLE; CANCER CELL CULTURE; COLON CARCINOMA; CONTROLLED STUDY; ENZYME ACTIVITY; EXPRESSION VECTOR; GENE DELETION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION REGULATION;

EID: 0031861729     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.18.7.4377     Document Type: Article

References (49)

1. Alland, L., R. Muhle, H. Hou, Jr., J. Potes, L. Chin, N. Schreiber-Agus, and R. A. Depinho. 1997. Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression. Nature 387:49-55.
2. Bartsch, J., M. Truss, J. Bode, and M. Beato. 1996. Moderate increase in histone acetylation activates the mouse mammary tumor virus promoter and remodels its nucleosome structure. Proc. Natl. Acad. Sci. USA 93:10741-10746.
3. Baxevanis, A. D., G. Arents, E. N. Moudrianakis, and D. Landsman. 1995. A variety of DNA-binding and multimeric proteins contein the histone fold motif. Nucleic Acids Res. 23:2685-2691.
4. Braunstein, M., A. B. Rose, S. G. Holmes, C. D. Allis, and J. R. Broach. 1993. Transcriptional silencing in yeast is associated with reduced nucleosome acetylation. Genes Dev. 7:592-604.
5. Brownell, J., J. Zhou, T. Ranalli, R. Kobayashi, D. Edmondson, S. Roth, and C. D. Allis. 1996. Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell 84:843-851.
6. Bucher, P. 1990. Weight matrix description of four eukaryotic RNA polymerase II promoter elements derived from 502 unrelated promoter sequences. J. Mol. Biol. 212:563-579.
7. Candau, R., J. X. Zhou, C. D. Allis, and S. L. Berger. 1997. Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo. EMBO J. 16:555-565.
8. Chomczynski, P., and N. Sacchi. 1996. Single-step RNA isolation from cultured cells or tissue, p. 4.2.2-4.23. In F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.), Current protocols in molecular biology, vol. 1. John Wiley & Sons, Inc., New York, N.Y.
9. Dorn, A., J. Bollekens, A. Staub, C. Benoist, and D. Mathis. 1987. A multiplicity of CCAAT box-binding proteins. Cell 50:863-872.
10. Frommel, T. O., J. S. Coon, T. Tsuruo, and I. B. Roninson. 1993. Variable effects of sodium butyrate on the expression and function of the MDR1 (P-glycoprotein) gene in colon carcinoma cell lines. Int. J. Cancer 55:297-302.
11. Germann, U. A., I. Pastan, and M. Gottesman. 1993. P-glycoproteins: mediators of multidrug resistance. Semin. Cell Biol. 4:63-76.
12. Gu, W., and R. G. Roeder. 1997. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 90:595-606.
13. Hassig, C. A., T. C. Fleischer, A. N. Billin, S. L. Schreiber, and D. E. Ayer. 1997. Histone deacetylase activity is required for full transcriptional repression by msin3a. Cell 89:341-347.
14. Hebbes, T. R., A. L. Clayton, A. W. Thorne, and C. Crane-Robinson. 1994. Core histone hyperacetyiation co-maps with generalized DNase I sensitivity in the chicken beta-globin chromosomal domain. EMBO J. 13:1823-1830.
15. Heinzel, T., R. M. Lavinsky, T.-M. Mullen, M. Soderstrom, C. D. Laherty, J. Torchia, W.-M. Yang, G. Brard, S. D. Ngo, J. R. Davie, E. Seto, R. N. Eisenman, D. W. Rose, C. K. Glass, and M. G. Rosenfeld. 1997. A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature 387:43-48.
16. Ince, T. A., and K. W. Scotto. 1995. A conserved downstream element defines a new class of RNA polymerase II promoters. J. Biol. Chem. 270:30249-30252.
17. Ince, T. A., and K. W. Scotto. 1996. Stable transfection of the P-glycoprotein promoter reproduces the endogenous overexpression phenotype: the role of MED-1. Cancer Res. 56:2021-2024.
18. Ince, T. A., and K. W. Scotto. 1997. Transcriptional regulation of multidrug resistant genes, p. 1751-1764. In J. R. Bertino (ed.), Encyclopedia of cancer, vol. 3. Academic Press, San Diego, Calif.
19. Jeppesen, P., and B. M. Turner. 1993. The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression. Cell 74:281-289.
20. 19a. Jin, S., and K. W. Scotto. Unpublished data.
21. Kaufman, P. D., R. Kobayashi, N. Kessler, and B. Stillman. 1995. The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication. Cell 81:1105-1114.
22. Laherty, C. D., W.-M. Yang, J.-M. Sun, J. R. Davie, E. Seto, and R. N. Eisenman. 1997. Histone deacetylases associated with the mSin3 corepressor mediate Mad transcriptional repression. Cell 89:349-356.
23. Lee, K. A., and M. R. Green. 1990. Small-scale preparation of extracts from radiolabeled cells efficient in pre-mRNA splicing. Methods Enzymol. 181:20-30.
24. Linhoff, M. W., K. L. Wright, and J. P.-Y. Ting. 1997. CCAAT-binding factor NF-Y and RFX are required for in vivo assembly of a nucleoprotein comp that spans 250 base pairs: the invariant chain promoter as a model. Mol. Cell. Biol. 17:4589-4596.
25. Maity, S. N., S. Sinha, E. C. Ruteshouser, and B. de Crombrugghe. 1992 Three different polypeptides are necessary for DNA binding of mammalian heteromeric CCAAT binding factor. J. Biol. Chem. 267:16574-16580.
26. Mantovani, R., U. Pessara, F. Tronche, X.-Y. Li, A.-M. Knapp, J.-L. Pasquali, C. Benoist, and D. Mathis. 1992. Monoclonal antibodies to NF-Y define its function in MHC class II and albumin gene transcription. EMBO J. 11:3315-3322.
27. Mantovani, R., X.-Y. Li, U. Pessara, R. H. van Huisjduijnen, C. Benoist, and D. Mathis. 1994. Dominant negative analogs of NF-YA. J. Biol. Chem. 269:20340-20346.
28. Mickley, L. A., S. E. Bates, N. D. Richert, S. Currier, S. Tanaka, F. Foss, N. Rosen, and A. T. Fojo. 1989. Modulation of the expression of a multidrug resistance gene (mdr-1/P-glycoprotein) by differentiating agents. J. Biol. Chem. 264:18031-18040.
29. Miyazaki, M., K. Kohno, T. Uchiumi, H. Tanimura, K.-I. Matsuo, M. Nasu, and M. Kuwano. 1992. Activation of human multidrug resistance-1 gene promoter in response to heat shock stress. Biochem. Biophys. Res. Commun. 187:677-684.
30. Mizzen, C. A., X. J. Yang, T. Kokubo, J. E. Brownell, A. J. Bannister, T. Owen-Hughes, J. Workman, L. Wang, S. L. Berger, T. Kouzarides, Y. Nakatani, and C. D. Allis. 1996. The TAF(II)250 subunit of TFIID has histone acetyltransferase activity. Cell 87:1261-1270.
31. Morrow, C. S., M. Nakagawa, M. E. Goldsmith, M. J. Madden, and K. B. Cowan. 1994. Reversible transcriptional activation of mdr1 by sodium butyrate treatment of human colon cancer cells. J. Biol. Chem. 269:10739-10745.
32. Nagy, L., H.-Y. Kao, D. Chakravarti, R. J. Lin, C. A. Hassig, D. E. Aver, S. Schreiber, and R. E. Evans. 1997. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A and histone deacetylase. Cell 89:373-380.
33. Nakshatri, H., P. Bhat-Nakshatri, and R. A. Currie. 1996. Subunit association and DNA binding activity of the heterotrimeric transcription factor NF-Y is regulated hy cellular redox. J. Biol. Chem. 271:28784-28791.
34. Ogryzko, V. V., R. L. Schiltz, V. Russanova, B. H. Howard, and Y. Nakatani. 1996. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87:953-959.
35. Ohga, T., K. Koike, M. Ono, Y. Makino, Y. Itagaki, M. Tanimoto, M. Kuwano, and K. Kohno. 1996. Role of the human Y box-binding protein YB1 in cellular sensitivity to the DNA-damaging agents cisplatin, mitomycin C. and ultraviolet light. Cancer Res. 56:4224-4228.
36. Promega Corporation. 1996. WI. Protocols and applications guide, 3rd ed., p. 47-48. Promega Corp., Madison, Wis.
37. Puri, P. L., V. Sartorelli, X.-J. Yang, Y. Hamamori, V. V. Ogryzko, B. Howard, L. Kedes, J. Y. J. Wang, A. Graessmann, Y. Nakatani, and M. Levrero. 1997. Differential roles of p300 and pCAF acetyltransferases in muscle differentiation. Mol. Cell 1:35-45.
38. Sinha, S., S. N. Maity, J. Lu, and B. de Crombrugghe. 1995. Recombinant rat CBF-C. the third subunit of CBF/NFY, allows formation of a protein-DNA complex with CBF-A and CBF-B and with yeast HAP2 and HAP3. Proc. Natl. Acad. Sci. USA 92:1624-1528.
39. Sundseth, R., G. MacDonald, J. Ting, and A. C. King. 1997. DNA elements recognizing NF-Y and Sp-1 regulate the human multidrug-resistance gene promoter. Mol. Pharmacol. 51:963-971.
40. Taunton, J., C. A. Hassig, and S. L. Schreiber. 1996. A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science 272:408-411.
41. Torchia, J., D. W. Rose, J. Inostroza, Y. Kamel, S. Westin, C. K. Glass, and M. G. Rosenfeld. 1997. The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function. Nature 387:677-684.
42. Van Lint, C., S. Emiliani, and E. Verdin. 1996. Transcriptional activation and chromatin remodeling of the HIV-1 promoter. EMBO J. 15:1112-1120.
43. Wang, L., C. Mizzen, C. Ying, R. Candau, N. Barlev, J. Brownell, D. Allis, and S. L. Berger. 1997. Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation. Mol. Cell. Biol. 17:519-527.
44. Wolffe, A. P., and D. Pruss. 1996. Targeting chromatin disruption: transcription regulators that acetylate histones. Cell 84:817-819.
45. Wolffe, A. P. 1997. Sinful repression. Nature 387:16-17.
46. Yang, X.-J., V. V. Ogryzko, J.-I. Nishikawa, B. H. Howard, and Y. Nakatam. 1996. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 382:319-324.
47. Yoshida, M., M. Kijima, M. Akita, and T. Beppu. 1990. Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A. J. Biol. Chem. 265:17174-17179.
48. Yoshida, M., S. Horinouchi, and T. Beppu. 1995. Trichostatin A and Tripoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function. Bioessays 17:423-430.
49. Zhang, Y., R. Iratni, H. Erdjument-Bromage, P. Tempst, and D. Reinberg. 1997. Histone deacetylase and SAP18, a novel polypeptide, are components of a human Sin3 complex. Cell 89:357-364.