Effect of mitogen-activated protein kinase signal transduction pathway on multidrug resistance induced by vincristine in gastric cancer cell line MGC803

World Journal of Gastroenterology

Volumn 10, Issue 6, 2004, Pages 795-799

  Chen, Bo ^a   Jin, Feng ^a   Lu, Ping ^a   Lu, Xiang Lu ^a   Wang, Ping Ping ^a   Liu, Yun Peng ^a   Yao, Fan ^a   Wang, Shu Bao ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; GLYCOPROTEIN P; MITOGEN ACTIVATED PROTEIN KINASE; VINCRISTINE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL STRUCTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; GENE EXPRESSION; GIEMSA STAIN; HUMAN; HUMAN CELL; IC 50; MULTIDRUG RESISTANCE; PHENOTYPE; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STOMACH CANCER; WESTERN BLOTTING;

EID: 1842483291     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v10.i6.795     Document Type: Article

References (36)

1. Zhang LJ, Chen KN, Xu GW, Xing HP, Shi XT. Congenital expression of mdr-1 gene in tissues of carcinoma and its relation with pathomorphology and prognosis. World J Gastroenterol 1999; 5: 53-56
2. Thottassery JV, Zambetti GP, Arimori K, Schuetz EG, Schuetz JD. p53-dependent regulation of MDR1 gene expression causes selective resistance to chemotherapeutic agents. Proc Natl Acad Sci U S A 1997; 94: 11037-11042
3. Nagata J, Kijima H, Hatanaka H, Asai S, Miyachi H, Abe Y, Yamazaki H, Nakamura M, Watanabe N, Mine T, Kondo T, Scanlon KJ, Ueyama Y. Reversal of drug resistance using hammerhead ribozymes against multidrug resistance-associated protein and multidrug resistance 1 gene. Int J Oncol 2002; 21: 1021-1026
4. Lage H, Perlitz C, Abele R, Tampe R, Dietel M, Schadendorf D, Sinha P. Enhanced expression of human ABC-transporter tap is associated with cellular resistance to mitoxantrone. FEBS Lett 2001; 503: 179-184
5. Zhan M, Yu D, Lang A, Li L, Pollock RE. Wild type p53 sensitizes soft tissue sarcoma cells to doxorubicin by down-regulating multidrug resistance-1 expression. Cancer 2001; 92: 1556-1566
6. Liu B, Staren E, Iwamura T, Appert H, Howard J. Effects of Taxotere on invasive potential and multidrug resistance phenotype in pancreatic carcinoma cell line SUIT-2. World J Gastroenterol 2001; 7:143-148
7. Stavrovskaya AA. Cellular mechanisms of multidrug resistance of tumor cells. Biochemistry 2000; 65: 95-106
8. van Brussel JP, van Steenbrugge GJ, Romijn JC, Schroder FH, Mickisch GH. Chemosensitivity of prostate cancer cell lines and expression of multidrug resistance-related proteins. Eur J Cancer 1999; 35: 664-671
9. Ruefli AA, Smyth MJ, Johnstone RW. HMBA induces activation of a caspase-independent cell death pathway to overcome P-glycoprotein-mediated multidrug resistance. Blood 2000; 95: 2378-2385
10. Bohacova V, Kvackajova J, Barancik M, Drobna Z, Breier A. Glutathione S-transferase does not play a role in multidrug resistance of L1210/VCR cell line. Physiol Res 2000; 49: 447-453
11. Smyth MJ, Krasovskis E, Sutton VR, Johnstone RW. The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis. Proc Natl Acad Sci U S A 1998; 95: 7024-7029
12. Naito S, Yokomizo A, Koga H. Mechanisms of drug resistance in chemotherapy for urogenital carcinoma. Int J Urol 1999; 6: 427-439
13. Warr JR, Bamford A, Quinn DM. The preferential induction of apoptosis in multidrug-resistance KB cells by 5-fluorouracil. Cancer Lett 2002; 175: 39-44
14. Roepe PD. PH and multidrug resistance. Novartis Found Symp 2001; 240: 232-247
15. Holzmayer TA, Hilsenbeck S, Von Hoff DD, Roninson IB. Clinical correlates of MDR1 (P-glycoprotein) gene expression in ovarian and small-cell lung carcinomas. J Natl Cancer Inst 1992; 84: 1486-1491
16. Chan HS, Thorner PS, Haddad G, Ling V. Immunohistochemical detection of P-glycoprotein: Prognostic correlation in soft tissue sarcoma of childhood. J Clin Oncol 1990; 8: 689-704
17. Tseng CP, Cheng AJ, Chang JT, Tseng CH, Wang HM, Liao CT, Chen IH, Tseng KC. Quantitative analysis of multidrug-resistance mdr1 gene expression in head and neck cancer by real-time RT-PCR. Jpn J Cancer Res 2002; 93: 1230-1236
18. Schondorf T, Kurbacher CM, Gohring UJ, Benz C, Becker M, Sartorius J, Kolhagen H, Mallman P, Neumann R. Induction of MDR1-gene expression by antineoplastic agents in ovarian cancer cell lines. Anticancer Res 2002; 22: 2199-2203
19. Kato A, Miyazaki M, Ambiru S, Yoshitomi H, Ito H, Nakagawa K, Shimizu H, Yokosuka O, Nakajima N. Multidrug resistance gene (MDR-1) expression as a useful prognostic factor in patients with human hepatocellular carcinoma after surgical resection. J Surg Oncol 2001; 78: 110-115
20. Sonneveld P. Multidrug resistance in haematological malignancies. J Intern Med 2000; 247: 521-534
21. Chaudhary PM, Roninson IB. Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs. J Natl Cancer Inst 1993; 85: 632-639
22. Zhang P, Wang D, Zheng G. Induction of multidrug resistance in Tca8113 cells by transient exposure to different chemotherapeutic drugs. Huaxi Kouqiang Yixue Zazhi 2003; 21: 70-73
23. Brugger D, Brischwein K, Liu C, Bader P, Niethammer D, Gekeler V, Beck JF. Induction of drug resistance and protein kinase C genes in A2780 ovarian cancer cells after incubation with antineoplastic agents at sublethal concentrations. Anticancer Res 2002; 22: 4229-4232
24. Schondorf T, Neumann R, Benz C, Becker M, Riffelmann M, Gohring UJ, Sartorius J, von Konig CH, Breidenbach M, Valter MM, Hoopmann M, Di Nicolantonio F, Kurbacher CM. Cisplatin, doxorubicin and paclitaxel induce mdr1 gene transcription in ovarian cancer cell lines. Recent Results Cancer Res 2003; 161: 111-116
25. Kisucka J, Barancik M, Bohacova V, Breier A. Reversal effect of specific inhibitors of extracellular-signal regulated protein kinase pathway on P-glycoprotein mediated vincristine resistance of L1210 cells. Gen Physiol Biophys 2001; 20: 439-444
26. Lewis TS, Shapiro PS, Ahn NG. Signal transduction through MAP kinase casecades. Adv Cancer Res 1998; 74: 49-139
27. Karin M. Mitogen-activated protein kinase cascades as regulators of stress responses. Ann N Y Acad Sci 1998; 851: 139-146
28. Evans DR, Hemmings BA. Signal transduction. What goes up must come down. Nature 1998; 394: 23-24
29. Chen J, Fujii K, Zhang L, Roberts T, Fu H. Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism. Proc Natl Acad Sci U S A 2001; 98: 7783-7788
30. Busca R, Abbe P, Mantoux F, Aberdam E, Peyssonnaux C, Eychene A, Ortonne JP, Ballotti R. Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes. EMBO J 2000; 19: 2900-2910
31. Payne DM, Rossomando AJ, Martino P, Erickson AK, Her JH, Shabanowitz J, Hunt DF, Weber MJ, Sturgill TW. Identification of the regulatory phosphorylation sites in pp42/mitogen- activated protein kinase (MAP kinase). EMBO J 1991; 10: 885-892
32. Dent P, Jarvis WD, Birrer MJ, Fisher PB, Schmidt-Ullrich RK, Grant S. The roles of signaling by the p42/p44 mitogen-activated protein (MAP) kinase pathway; a potential route to radio- and chemo- sensitization of tumor cells resulting in the induction of apoptosis and loss of clonogenicity, Leukemia 1998; 12: 1843-1850
33. Ding S, Chamberlain M, McLaren A, Goh L, Duncan I, Wolf CR. Cross-talk between signalling pathways and the multidrug resistant protein MDR-1. Br J Cancer 2001; 85: 1175-1184
34. Kim MS, So HS, Park JS, Lee KM, Moon BS, Lee HS, Kim TY, Moon SK, Park R. Hwansodan protects PC12 cells against serum-deprivation-induced apoptosis via a mechanism involving Ras and mitogen-activated protein (MAP) kinase pathway. Gen Pharmacol 2000; 34: 227-235
35. Fritz F, Howard EM, Hoffman MM, Roepe PD. Evidence for altered ion transport in Saccharomyces cerevisiae overexpressing human MDR1 protein. Biochemistry 1999; 38: 4214-4226
36. Wittstein IS, Qiu W, Ziegelstein RC, Hu Q, Kass DA. Opposite effects of pressurized steady versus pulsatile perfusion on vascular endothelial cell cytosolic pH: role of tyrosine kinase and mitogen-activated protein kinase signaling. Circ Res 2000; 86: 1230-1236