How NF-κB is activated: The role of the IκB kinase (IKK) complex

Oncogene

Volumn 18, Issue 49, 1999, Pages 6867-6874

  Karin, Michael ^a  

^a San Diego   (United States)

Author keywords

IKK; I B; Kinase; NF B; Phosphorylation; Proteasome; Rel; Signal transduction

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR PROTEIN; PROTEIN KINASE; CHUK PROTEIN, HUMAN; I KAPPA B KINASE; IKBKB PROTEIN, HUMAN; IKBKE PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE; RELB PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELB;

ENZYME SUBUNIT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; REVIEW; TRANSCRIPTION REGULATION; ANIMAL; HUMAN; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; HUMANS; I-KAPPA B KINASE; NF-KAPPA B; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; TRANSCRIPTION FACTOR RELB; TRANSCRIPTION FACTORS;

EID: 0033595893     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203219     Document Type: Review

References (72)

1. Aberle H, Bauer A, Stappert J, Kispert A and Kemler R. (1997). EMBO J., 16, 3797-3804.
2. Alkalay I, Yaron A, Hatzubai A, Jung S, Avraham A, Gerlitz O, Pashut-Lavon T and Ben-Neriah, Y. (1995). Mol. Cell. Biol., 15, 1294-1301.
3. Arenzana-Seisdedos F, Turpin P, Rodriguez M, Thomas D, Hay RT, Virelizier JL and Dargemont C. (1997). J. Cell Sci., 110, 369-378.
4. Bacuerle PA and Baltimore D. (1996). Cell, 87, 13-20.
5. Bai C, Sen P, Hofmann K, Ma L, Goebl M, Harper JW and Elledge SJ. (1996). Cell, 86, 263-274.
6. Baldwin Jr AS. (1996). Annu. Rev. Immunol., 14, 649-681.
7. Bargou RC, Emmerich F, Krappmann D, Bommert K, Mapara MY, Arnold W, Royer HD, Grinstein E, Greiner A, Scheidereit C and Dèorken B. (1997). J. Clin. Invest., 100, 2961-2969.
8. Barnes PJ and Karin M. (1997). New Engl. J. Med., 336, 1066-1071.
9. Baud V, Liu Z-G, Bennett B, Suzuki N, Xia Y and Karin M. (1999). Genes Dev., 13, 1297-1308.
10. Beg AA and Baltimore D. (1996). Science, 274, 782-784.
11. Beg AA, Sha WC, Bronson RT, Ghosh S and Baltimore D. (1995). Nature, 376, 167-169.
12. Belvin MP and Anderson KV. (1996). Annu. Rev. Dev. Biol., 12, 393-416.
13. Bender K, Gottlicher M, Whiteside S, Rahmsdorf HJ and Herrlich P. (1998). EMBO J., 17, 5170-5181.
14. Beraud C, Henzel WJ and Baeuerle PA. (1999). Proc. Nat. Acad. Sci. USA, 96, 429-434.
15. Brown K, Gerstberger S. Carlson L, Franzoso G and Siebenlist U. (1995). Science, 267, 1485-1491.
16. Chen FE and Ghosh G. (1999). Oncogene, 18, 6845-6852.
17. Chen Z, Hagler J, Palombella VJ, Melandri F, Scherer D, Ballard D and Maniatis T. (1995). Genes Dev., 9, 1586-1597.
18. Cohen L, Henzel WJ and Baeuerle PA. (1998). Nature, 395, 292-296.
19. Delhase M, Hayakawa M, Chen Y and Karin M. (1999). Science, 284, 309-313.
20. DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E and Karin M. (1997). Nature, 388, 548-554.
21. DiDonato JA, Mercurio F and Karin M. (1995). Mol. Cell. Biol., 15, 1302-1311.
22. DiDonato JA, Mercurio F, Rosette C, Wu-Li J, Suyang H, Ghosh S and Karin M. (1996). Mol. Cell. Biol., 16, 1295-1304.
23. Doi TS, Marino MW, Takahashi T, Yoshida T, Sakakura T, Old LJ and Obata Y. (1999). Proc. Natl. Acad. Sci. USA, 96, 2994-2999.
24. Feldman RMR, Correll CC, Kaplan KB and Deshaies RJ. (1997). Cell, 91, 221-230.
25. Gerondakis S, Grossmann M, Nakamura Y, Pohl T and Grumont R. (1999). Oncogene, 18, 6888-6895.
26. Gilmore TD. (1997). J. Clin. Invest., 100, 2935-2936.
27. Hershko A and Ciechanover A. (1998). Annu. Rev. Biochem., 67, 425-479.
28. Hoffmann JA, Kafatos FC, Janeway CAJ and Ezekowiz RAB. (1999). Science, 284, 1313-1318.
29. Horwitz BH, Scott ML, Cherry SR, Bronson RT and Baltimore D. (1997). Immunity, 6, 765-772.
30. Hu Y, Baud V, Delhase M, Zhang P, Deerinck T, Ellisman M, Johnson R and Karin M. (1999). Science, 284, 316-320.
31. Imbert V, Rupec RA, Livolsi A, Pahl HL, Traenekner EB, Mueller-Dieckmann C, Farahifar D, Rossi R, Auberger P, Baeuerle PA and Peyron JF. (1996). Cell, 86, 787-798.
32. Jiang J and Struhl G. (1998). Nature, 391, 493-496.
33. Johnson LN, Noble MEM and Owen DJ. (1996). Cell, 85, 149-158.
34. Karin M and Delhase M. (1998). Proc. Natl. Acad. Sci. USA, 95, 9067-9069.
35. Krappmann D, Emmerich F, Kordes U, Scharschmidt E, Dörken B and Scheidereit C. (1999). Oncogene, 18, 943-953.
36. Li N and Karin M. (1998). Proc. Natl. Acad. Sci. USA, 95, 13012-13017.
37. Li Q, Van Antwerp D, Mercurio F, Lee K-F and Verma IM. (1999a). Science, 284, 321-325.
38. Li Y, Kang J, Friedman J, Tarassishin L, Ye J, Kovalenko A, Wallach D and Horwitz MS. (1999b), Proc. Natl. Acad. Sci. USA, 96, 1042-1047.
39. Li Z-W, Chu W, Hu Y, Delhase M, Deerinck T, Ellisman M, Johnson R and Karin M. (1999c). J Exp. Med., 189, 1839-1845.
40. Ling L, Cao Z and Goeddel DV. (1998). Proc. Natl. Acad. Sci. USA, 95, 2791-2797.
41. Lui Z-G, Hu H, Goeddel DV and Karin M. (1996). Cell, 87, 565-576.
42. Malinin NL, Boldin MP, Kovalenko AV and Wallach D. (1997). Nature, 385, 540-544.
43. Margottin F, Bour SP, Durand H, Selig L, Benichou S, Richard V, Thomas D, Strebel K and Benarous R. (1998). Mol. Cell, 1, 565-574.
44. Mercurio F, Murray BW, Shevehenko A, Bennett BL, Young DB, Li JW, Pascual G, Motiwala A, Zhu H, Mann M and Manning AM. (1999). Mol. Cell. Biol., 19, 1526-1538.
45. Mercurio F, Zhu H, Murray BW, Shevehenko A, Bennett BL, Li J, Young DB, Barbosa M, Mann M, Manning A and Rao A. (1997). Science, 278, 860-866.
46. Otero G, Fellows J, Li Y, de Bizemont T, Dirac AM, Gustafsson CM, Erdjument-Bromage H, Tempst P and Svejstrup JQ. (1999). Mol. Cell, 3, 109-118.
47. Pahl HL. (1999). Oncogene, 18, 6853-6866.
48. Patton EE, Willems AR. and Tyers M. (1998). Trends Genet., 14, 236-243.
49. Rayet B and Gélinas C. (1999). Oncogene, 18, 6938-6947.
50. Reach M, Galindo RL, Towb P, Allen JL, Karin M and Wasserman SA. (1996). Dev. Biol., 180, 353-364.
51. Régnier CH, Song HY, Gao X, Goeddel DV, Cao Z and Rothe M. (1997). Cell, 90, 373-383.
52. Rothwarf DM, Zandi E, Natoli G and Karin M. (1998). Nature, 395, 297-300.
53. Sachdev S, Hoffmann A and Hannink M. (1998). Mol. Cell. Biol., 18, 2524-2534.
54. Scherer DC, Brockman J, Chen Z, Maniatis T and Ballard D. (1995). Proc. Natl. Acad. Sci. USA, 92, 11259-11263.
55. Seitz CS, Lin Q, Deng H and Khavari PA. (1998). Proc. Natl. Acad. Sci. USA, 95, 2307-2312.
56. Shinkura R, Kitada K, Matsuda F, Tashiro K, Ikuta K, Suzuki M, Kogishi K, Scrikawa T and Honjo T. (1999). Naure. Genet., 22, 74-77.
57. Skowyra D, Craig KL, Tyers M, Elledge SJ and Harper JW. (1997). Cell. 91, 209-219.
58. Sun S-C and Ballard DW. (1999). Oncogene, 18, 6948-6958.
59. Takeda K, Takeuchi O, Tsujimura T, Itami S, Adachi O, Kawai T, Sanjo H, Yoshikawa K, Terada N and Akira S. (1999). Science, 284, 313-316.
60. Tanaka M, Fuentes ME, Yamaguchi K, Durnin MH, Dalrymple SA, Hardy KL and Goeddel DV. (1999). Immunity, 10, 421-429.
61. Uhlik M, Good L, Xiao G, Harhaj EW, Zandi E, Karin M and Sun S-C. (1998). J. Biol. Chem., 273, 21132-21136.
62. Van Antwerp DJ, Martin SJ, Kafri T, Green DR and Verma IM. (1996). Science, 274, 787-789.
63. Verma IM, Stevenson JK, Schwarz EM, Van Antwerp D and Miyamoto S. (1995). Genes Dev. 9, 2723-2735.
64. Wang C-Y, Mayo MW and Baldwin Jr AS. (1996). Science, 274, 784-787.
65. Winston JT, Strack P, Beer-Romero P, Chu CY, Elledge SJ and Harper JW. (1999). Genes Dev., 13, 270-283.
66. Woronicz JD, Gao X, Cao Z, Rothe M. and Goeddel DV. (1997). Science, 278, 866-869.
67. Yamaoka S, Courtois G, Bessia C, Whiteside ST, Weil R, Agon F, Kirk HE, Kay RJ and Israël A. (1998). Cell, 93, 1231-1240.
68. Yaron A, Gonen H, Alkalay I, Hatzubai A, Jung S, Beyth S, Mercurio F, Manning AM, Ciechanover A. and Ben-Neriah Y. (1997). EMBO J., 16, 6486-6494.
69. Yaron A, Hatzubai A, Davis M, Lavon I, Amit S, Manning AM, Anderson JS, Mann M, Mercurio F and Ben-Neriah Y. (1998). Nature, 396, 590-594.
70. Zandi E, Chen Y and Karin M. (1998). Science, 281, 1360-1363.
71. Zandi E, Rothwarf DM, Delhase M, Hayakawa M and Karin M. (1997). Cell, 91, 243-252.
72. Zheng C-F and Guan K-L. (1994). EMBO J., 13, 1123-1131.