NF-κB activation by camptothecin. A linkage between nuclear dna damage and cytoplasmic signaling events

Journal of Biological Chemistry

Volumn 275, Issue 13, 2000, Pages 9501-9509

  Huang, Tony T ^a   Wuerzberger Davis, Shelly M ^a   Seufzer, Bradley J ^a   Shumway, Stuart D ^a   Kurama, Takeshi ^a   Boothman, David A ^a,b   Miyamoto, Shigeki ^a,c  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APHIDICOLIN; CAMPTOTHECIN; DNA TOPOISOMERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; CYSTEINE PROTEINASE; DNA BINDING PROTEIN; I KAPPA B; MULTIENZYME COMPLEX; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PRIMER DNA; PROTEASOME; TOPOTECAN; UBIQUITIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE S PHASE; CYTOTOXICITY; DNA DAMAGE; DNA REPLICATION; DNA STRAND BREAKAGE; ENZYME ACTIVITY; GENE TRANSLOCATION; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; CELL NUCLEUS; CYTOPLASM; DRUG ANTAGONISM; DRUG EFFECT; HELA CELL; METABOLISM; NUCLEOTIDE SEQUENCE;

APOPTOSIS; BASE SEQUENCE; CAMPTOTHECIN; CELL NUCLEUS; CYSTEINE ENDOPEPTIDASES; CYTOPLASM; DNA DAMAGE; DNA PRIMERS; DNA REPLICATION; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; I-KAPPA B PROTEINS; MULTIENZYME COMPLEXES; NF-KAPPA B; PROTEASOME ENDOPEPTIDASE COMPLEX; S PHASE; SIGNAL TRANSDUCTION; TOPOTECAN; UBIQUITINS;

EID: 0034737193     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.13.9501     Document Type: Article

References (82)

1. Baeuerle, P. A., and Baltimore, D. (1996) Cell 87, 13-20
2. Verma, I. M., Stevenson, J. K., Schwarz, E. M., Van Antwerp, D., and Miyamoto, S. (1995) Genes Dev. 9, 2723-2735
3. Sonenshein, G. E. (1997) Semin. Cancer Biol. 8, 113-119
4. Beg, A. A., Ruben, S. M., Scheinman, R. I., Haskill, S., Rosen, C. A., and Baldwin, A. S. J. (1992) Genes Dev. 6, 1899-1913
5. Ganchi, P. A., Sun, S. C., Greene, W. C., and Ballard, D. W. (1992) Mol. Biol. Cell 3, 1339-1352
6. Chen, Z. J., Parent, L., and Maniatis, T. (1996) Cell 84, 853-862
7. DiDonato, J. A., Hayakawa, M., Rothwarf, D. M., Zandi, E., and Karin, M. (1997) Nature 388, 548-554
8. Mercurio, F., Zhu, H., Murray, B. W., Shevchenko, A., Bennett, B. L., Li, J. W., Young, D. B., Barbosa, M., Mann, M., Manning, A., and Rao, A. (1997) Science 278, 860-866
9. Woronicz, J. D., Gao, X., Cao, Z., Rothe, M., and Goeddel, D. V. (1997) Science 278, 866-869
10. Zandi, E., Rothwarf, D. M., Delhase, M., Hayakawa, M., and Karin, M. (1997) Cell 91, 243-252
11. Alkalay, I., Yaron, A., Hatzubai, A., Orian, A., Ciechanover, A., and Ben-Neriah, Y. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 10599-10603
12. Chen, Z., Hagler, J., Palombella, V. J., Melandri, F., Scherer, D., Ballard, D., and Maniatis, T. (1995) Genes Dev. 9, 1586-1597
13. Li, N., and Karin, M. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 13012-13017
14. Bender, K., Gottlicher, M., Whiteside, S., Rahmsdorf, H. J., and Herrlich, P. (1998) EMBO J. 17, 5170-5181
15. Han, Y., Weinman, S., Boldogh, I., Walker, R. K., and Brasier, A. R. (1999) J. Biol. Chem. 274, 787-794
16. Chen, F., Lu, Y., Kuhn, D. C., Maki, M., Shi, X., Sun, S. C., and Demers, L. M. (1997) Arch. Biochem. Biophys. 342, 383-388
17. Imbert, V., Rupec, R. A., Livolsi, A., Pahl, H. L., Traenckner, E. B. M., Mueller-Dieckmann, C., Farahifar, D., Rossi, B., Auberger, P., Baeuerle, P. A., and Peyron, J. F. (1996) Cell 86, 787-798
18. Stein, B., Kramer, M., Rahmsdorf, H. J., Ponta, H., and Herrlich, P. (1989) J. Virol. 63, 4540-4544
19. Piret, B., and Piette, J. (1996) Nucleic Acids Res. 24, 4242-4248
20. Devary, Y., Rosette, C., DiDonato, J. A., and Karin, M. (1993) Science 261, 1442-1445
21. Coffer, P. J., Burgering, B. M., Peppelenbosch, M. P., Bos, J. L., and Kruijer, W. (1995) Oncogene 11, 561-569
22. Herrlich, P., Blattner, C., Knebel, A., Bender, K., and Rahmsdorf, H. J. (1997) Biol. Chem. 378, 1217-1229
23. Rosette, C., and Karin, M. (1996) Science 274, 1194-1197
24. Tobin, D., van Hogerlindern, M., and Toftgard, R. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 565-569
25. Knebel, A., Rahmsdorf, H. J., Ullrich, A., and Herrlich, P. (1996) EMBO J. 15, 5314-5325
26. Miyamoto, S., Wuerzberger, S. M., Seufzer, B., and Boothman, D. A. (1997) Proc. Am. Assoc. Cancer Res. 38, 624
27. Hsiang, Y. H., and Liu, L. F. (1988) Cancer Res. 48, 1722-1726
28. Giovanella, B. C., Stehlin, J. S., Wall, M. E., Wani, M. C., Nicholas, A. W., Liu, L. F., Silber, R., and Potmesil, M. (1989) Science 246, 1046-1048
29. Liu, L. F. (1989) Annu. Rev. Biochem. 58, 351-375
30. Wang, J. C. (1996) Annu. Rev. Biochem. 65, 635-692
31. Hsiang, Y. H., Hertzberg, R., Hecht, S., and Liu, L. F. (1985) J. Biol. Chem. 260, 14873-14878
32. Covey, J. M., Jaxel, C., Kohn, K. W., and Pommier, Y. (1989) Cancer Res. 49, 5016-5022
33. Hsiang, Y.-H., Lihou, M. G., and Liu, L. F. (1989) Cancer Res. 49, 5077-5082
34. Slichenmyer, W. J., Rowinsky, E. K., Donehower, R. C., and Kaufmann, S. H. (1993) J. Natl. Cancer Inst. 85, 271-291
35. Rothenberg, M. L. (1997) Ann. Oncol. 8, 837-855
36. Miyamoto, S., Seufzer, B., and Shumway, S. (1998) Mol. Cell. Biol. 18, 19-29
37. Poste, G. (1972) Exp. Cell Res. 73, 273-286
38. Cao, Z. D., Xiong, J., Takeuchi, M., Kurama, T., and Goeddel, D. V. (1996) Nature 383, 443-446
39. Chiao, P. J., Miyamoto, S., and Verma, I. M. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 28-32
40. VanAntwerp, D. J., and Verma, I. M. (1996) Mol. Cell. Biol. 16, 6037-6045
41. Wuerzberger, S. M., Pink, J. J., Planchon, S. M., Byers, K. L., Bornmann, W. G., and Boothman, D. A. (1998) Cancer Res. 58, 1876-1885
42. Lin, J. H., and Castora, F. J. (1995) Arch. Biochem. Biophys. 324, 293-299
43. Baeuerle, P. A., and Baltimore, D. (1988) Science 242, 540-546
44. Fujimori, A., Hoki, Y., Popescu, N. C., and Pommier, Y. (1996) Oncol. Res. 8, 295-301
45. Fujimori, A., Harker, W. G., Kohlhagen, G., Hoki, Y., and Pommier, Y. (1995) Cancer Res. 55, 1339-1346
46. D'Arpa, P., Beardmore, C., and Liu, L. F. (1990) Cancer Res. 50, 6919-6924
47. Brockman, J. A., Scherer, D. C., McKinsey, T. A., Hall, S. M., Qi, X., Lee, W. Y., and Ballard, D. W. (1995) Mol. Cell. Biol. 15, 2809-2818
48. Brown, K., Gerstberger, S., Carlson, L., Franzoso, G., and Siebenlist, U. (1995) Science 267, 1485-1488
49. Traenckner, E. B., Pahl, H. L., Henkel, T., Schmidt, K. N., Wilk, S., and Baeuerle, P. A. (1995) EMBO J. 14, 2876-2883
50. Scherer, D. C., Brockman, J. A., Chen, Z., Maniatis, T., and Ballard, D. W. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 11259-11263
51. Li, Q., Lu, Q., Hwang, J. Y., Buscher, D., Lee, K. F., Izpisua-Belmonte, J. C., and Verma, I. M. (1999) Genes Dev. 13, 1322-1328
52. Li, Q., Van Antwerp, D., Mercurio, F., Lee, K. F., and Verma, I. M. (1999) Science 284, 321-325
53. Li, Z. W., Chu, W., Hu, Y., Delhase, M., Deerinck, T., Ellisman, M., Johnson, R., and Karin, M. (1999) J. Exp. Med. 189, 1839-1845
54. Tanaka, M., Fuentes, M. E., Yamaguchi, K., Durnin, M. H., Dalrymple, S. A., Hardy, K. L., and Goeddel, D. V. (1999) Immunity 10, 421-429
55. Hu, Y., Baud, V., Delhase, M., Zhang, P., Deerinck, T., Ellisman, M., Johnson, R., and Karin, M. (1999) Science 284, 316-320
56. Yamaoka, S., Courtois, G., Bessia, C., Whiteside, S. T., Weil, R., Agou, F., Kirk, H. E., Kay, R. J., and Israel, A. (1998) Cell 93, 1231-1240
57. Beg. A. A., and Baltimore, D. (1996) Science 274, 782-784
58. Wang, C. Y., Mayo, M. W., and Baldwin, A. S. (1996) Science 274, 784-787
59. VanAntwerp, D. J., Martin, S. J., Kafri, T., Green, D. R., and Verma, I. M. (1996) Science 274, 787-789
60. Hirano, M., Osada, S., Aoki, T., Hirai, S., Hosaka, M., Inoue, J., and Ohno, S. (1996) J. Biol. Chem. 271, 13234-13238
61. Lee, F. S., Hagler, J., Chen, Z. J., and Maniatis, T. (1997) Cell 88, 213-222
62. Yin, M. J., Christerson, L. B., Yamamoto, Y., Kwak, Y. T., Xu, S., Mercurio, F., Barbosa, M., Cobb, M. H., and Gaynor, R. B. (1998) Cell 93, 875-884
63. Cheng, G., Cleary, A. M., Ye, Z. S., Hong, D. I., Lederman, S., and Baltimore, D. (1995) Science 267, 1494-1498
64. Cheng, G., and Baltimore, D. (1996) Genes Dev. 10, 963-973
65. Ishida, T., Mizushima, S., Azuma, S., Kobayashi, N., Tojo, T., Suzuki, K., Aizawa, S., Watanabe, T., Mosialos, G., Kieff, E., Yamamoto, T., and Inoue, J. (1996) J. Biol. Chem. 271, 28745-28748
66. Rothe, M., Sarma, V., Dixit, V. M., and Goeddel, D. V. (1995) Science 269, 1424-1427
67. Malinin, N. L., Boldin, M. P., Kovalenko, A. V., and Wallach, D. (1997) Nature 385, 540-544
68. Tsukamoto, N., Kobayashi, N., Azuma, S., Yamamoto, T., and Inoue, J. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 1234-1239
69. Desai, S. D., Liu, L. F., Vazquez-Abad, D., and D'Arpa, P. (1997) J. Biol. Chem. 272, 24159-24164
70. Ryan, A. J., Squires, S., Strutt, H. L., Evans, A., and Johnson, R. T. (1994) Carcinogenesis 15, 823-828
71. Schulze-Osthoff, K., Beyaert, R., Vandevoorde, V., Haegeman, G., and Fiers, W. (1993) EMBO J. 12, 3095-3104
72. Schreck, R., Albermann, K., and Baeuerle, P. A. (1992) Free Radical Res. Commun. 17, 221-237
73. Zandi, E., Chen, Y., and Karin, M. (1998) Science 281, 1360-1363
74. Regnier, C. H., Song, H. Y., Gao, X., Goeddel, D. V., Cao, Z., and Rothe, M. (1997) Cell 90, 373-383
75. Wu, M., Lee, H. Y., Bellas, R. E., Schauer, S. L., Arsura, M., Katz, D., Fitzgerald, M. J., Rothstein, T. L., Sherr, D. H., and Sonenshein, G. E. (1996) EMBO J. 15, 4682-4690
76. Wu, M. X., Ao, S., Prasad, K. V. S., Wu, R., and Schlossman, S. F. (1998) Science 281, 998-1001
77. Chu, Z.-L., McKinsey, T. A., Liu, L., Gentry, J. J., Halim, M. H., and Ballard, D. W. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 10057-10062
78. Wang, C. Y., Mayo, M. W., Korneluk, R. G., Goeddel, D. V., and Baldwin, A. S. (1998) Science 281, 1680-1683
79. Wang, C. Y., Cusack, J. C. J., Liu, R., and Baldwin, A. S. (1999) Nat. Med. 5, 412-417
80. Huang, T. T., Kudo, N., Yoshida, M., and Miyamoto, S. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 1014-1019
81. Piret, B., Schoonbroodt, S., and Piret, J. (1999) Oncogene 18, 2261-2271
82. Basu, S., Rosenzweig, K. R., Youmell, M., and Price, B. D. (1998) Biochem. Biophys. Res. Commun. 247, 79-83