메뉴 건너뛰기




Volumn 131, Issue 8, 2004, Pages 1663-1677

LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling: Arrows point the way

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; BETA CATENIN; CELL PROTEIN; CHOLESTEROL; FRIZZLED PROTEIN; GLUCOSE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; MEMBRANE PROTEIN; MEMBRANE RECEPTOR; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 2342430345     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01117     Document Type: Review
Times cited : (909)

References (142)
  • 1
    • 0036111153 scopus 로고    scopus 로고
    • Planar signaling and morphogenesis in Drosophila
    • Adler, P. N. (2002). Planar signaling and morphogenesis in Drosophila. Dev. Cell 2, 525-535.
    • (2002) Dev. Cell , vol.2 , pp. 525-535
    • Adler, P.N.1
  • 2
    • 0035873390 scopus 로고    scopus 로고
    • Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling
    • Axelrod, J. D. (2001). Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling. Genes Dev. 15, 1182-1187.
    • (2001) Genes Dev. , vol.15 , pp. 1182-1187
    • Axelrod, J.D.1
  • 3
    • 0032529161 scopus 로고    scopus 로고
    • Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways
    • Axelrod, J. D., Miller, J. R., Shulman, J. M., Moon, R. T. and Perrimon, N. (1998). Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev. 12, 2610-2622.
    • (1998) Genes Dev. , vol.12 , pp. 2610-2622
    • Axelrod, J.D.1    Miller, J.R.2    Shulman, J.M.3    Moon, R.T.4    Perrimon, N.5
  • 5
    • 0034933057 scopus 로고    scopus 로고
    • Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow
    • Bafico, A., Liu, G., Yaniv, A., Gazit, A. and Aaronson, S. A. (2001). Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat. Cell Biol. 3, 683-686.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 683-686
    • Bafico, A.1    Liu, G.2    Yaniv, A.3    Gazit, A.4    Aaronson, S.A.5
  • 8
    • 0036713566 scopus 로고    scopus 로고
    • Pygopus encodes a nuclear protein essential for wingless/Wnt signaling
    • Belenkaya, T. Y., Han, C., Standley, H. J., Lin, X., Houston, D. W. and Heasman, J. (2002). pygopus encodes a nuclear protein essential for wingless/Wnt signaling. Development 129, 4089-4101.
    • (2002) Development , vol.129 , pp. 4089-4101
    • Belenkaya, T.Y.1    Han, C.2    Standley, H.J.3    Lin, X.4    Houston, D.W.5    Heasman, J.6
  • 10
    • 0032588683 scopus 로고    scopus 로고
    • Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development
    • Bhanot, P., Fish, M., Jemison, J. A., Nusse, R., Nathans, J. and Cadigan, K. M. (1999). Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development. Development 126, 4175-4186.
    • (1999) Development , vol.126 , pp. 4175-4186
    • Bhanot, P.1    Fish, M.2    Jemison, J.A.3    Nusse, R.4    Nathans, J.5    Cadigan, K.M.6
  • 11
    • 0032434512 scopus 로고    scopus 로고
    • Frizzled and frizzled 2 play a partially redundant role in wingless signaling and have similar requirements to wingless in neurogenesis
    • Bhat, K. M. (1998). frizzled and frizzled 2 play a partially redundant role in wingless signaling and have similar requirements to wingless in neurogenesis. Cell 95, 1027-1036.
    • (1998) Cell , vol.95 , pp. 1027-1036
    • Bhat, K.M.1
  • 12
    • 0034644526 scopus 로고    scopus 로고
    • Linking colorectal cancer to Wnt signaling
    • Bienz, M. and Clevers, H. (2000). Linking colorectal cancer to Wnt signaling. Cell 103, 311-320.
    • (2000) Cell , vol.103 , pp. 311-320
    • Bienz, M.1    Clevers, H.2
  • 13
    • 0037338999 scopus 로고    scopus 로고
    • Armadillo/beta-catenin signals in the nucleus - Proof beyond a reasonable doubt?
    • Bienz, M. and Clevers, U. (2003). Armadillo/beta-catenin signals in the nucleus - proof beyond a reasonable doubt? Nat. Cell Biol. 5, 179-182.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 179-182
    • Bienz, M.1    Clevers, U.2
  • 14
    • 0034625641 scopus 로고    scopus 로고
    • Signaling specificity by Frizzled receptors in Drosophila
    • Boutros, M., Mihaly, J., Bouwmeester, T. and Mlodzik, M. (2000). Signaling specificity by Frizzled receptors in Drosophila. Science 288, 1825-1828.
    • (2000) Science , vol.288 , pp. 1825-1828
    • Boutros, M.1    Mihaly, J.2    Bouwmeester, T.3    Mlodzik, M.4
  • 15
    • 0032967755 scopus 로고    scopus 로고
    • Dishevelled: At the crossroads of divergent intracellular signaling pathways
    • Boutros, M. and Mlodzik, M. (1999). Dishevelled: at the crossroads of divergent intracellular signaling pathways. Mech. Dev. 83, 27-37.
    • (1999) Mech. Dev. , vol.83 , pp. 27-37
    • Boutros, M.1    Mlodzik, M.2
  • 17
    • 0036337388 scopus 로고    scopus 로고
    • Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins
    • Brott, B. K. and Sokol, S. Y. (2002). Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins. Mol. Cell Biol. 22, 6100-6110.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 6100-6110
    • Brott, B.K.1    Sokol, S.Y.2
  • 20
    • 0032577556 scopus 로고    scopus 로고
    • Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing
    • Cadigan, K. M., Fish, M. P., Rulifson, E. J. and Nusse, R. (1998). Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing. Cell 93, 767-777.
    • (1998) Cell , vol.93 , pp. 767-777
    • Cadigan, K.M.1    Fish, M.P.2    Rulifson, E.J.3    Nusse, R.4
  • 21
    • 0037126331 scopus 로고    scopus 로고
    • The DIX domain targets dishevelled to actin stress fibres and vesicular membranes
    • Capelluto, D. G., Kutateladze, T. G., Habas, R., Finkielstein, C. V., He, X. and Overduin, M. (2002). The DIX domain targets dishevelled to actin stress fibres and vesicular membranes. Nature 419, 726-729.
    • (2002) Nature , vol.419 , pp. 726-729
    • Capelluto, D.G.1    Kutateladze, T.G.2    Habas, R.3    Finkielstein, C.V.4    He, X.5    Overduin, M.6
  • 23
    • 0033398530 scopus 로고    scopus 로고
    • Wingless transduction by the Frizzled and Frizzled2 proteins of Drosophila
    • Chen, C. M. and Struhl, G. (1999). Wingless transduction by the Frizzled and Frizzled2 proteins of Drosophila. Development 126, 5441-5452.
    • (1999) Development , vol.126 , pp. 5441-5452
    • Chen, C.M.1    Struhl, G.2
  • 25
    • 0037513408 scopus 로고    scopus 로고
    • A role of Dishevelled in relocating Axin to the plasma membrane during Wingless signaling
    • Cliffe, A., Hamada, F. and Bienz, M. (2003). A role of Dishevelled in relocating Axin to the plasma membrane during Wingless signaling. Curr. Biol. 13, 960-966.
    • (2003) Curr. Biol. , vol.13 , pp. 960-966
    • Cliffe, A.1    Hamada, F.2    Bienz, M.3
  • 26
    • 1542297761 scopus 로고    scopus 로고
    • Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of β-catenin
    • Cong, F. and Varmus, H. (2004). Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of β-catenin. Proc. Natl. Acad. Sci. USA 101, 2882-2887.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 2882-2887
    • Cong, F.1    Varmus, H.2
  • 27
    • 0242637406 scopus 로고    scopus 로고
    • Requirement for a nuclear function of beta-catenin in Wnt signaling
    • Cong, F., Schweizer, L., Chamorro, M. and Varmus, H. (2003). Requirement for a nuclear function of beta-catenin in Wnt signaling. Mol. Cell Biol. 23, 8462-8470.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 8462-8470
    • Cong, F.1    Schweizer, L.2    Chamorro, M.3    Varmus, H.4
  • 28
    • 0029811434 scopus 로고    scopus 로고
    • Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C
    • Cook, D., Fry, M. J., Hughes, K., Sumathipala, R., Woodgett, J. R. and Dale, T. C. (1996). Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C. EMBO J. 15, 4526-4536.
    • (1996) EMBO J. , vol.15 , pp. 4526-4536
    • Cook, D.1    Fry, M.J.2    Hughes, K.3    Sumathipala, R.4    Woodgett, J.R.5    Dale, T.C.6
  • 29
    • 0037423256 scopus 로고    scopus 로고
    • Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila
    • Culi, J. and Mann, R. S. (2003). Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila. Cell 112, 343-354.
    • (2003) Cell , vol.112 , pp. 343-354
    • Culi, J.1    Mann, R.S.2
  • 30
    • 0036927738 scopus 로고    scopus 로고
    • Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning
    • Davidson, G., Mao, B., del Barco Barrantes, I. and Niehrs, C. (2002). Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning. Development 129, 5587-5596.
    • (2002) Development , vol.129 , pp. 5587-5596
    • Davidson, G.1    Mao, B.2    del Barco Barrantes, I.3    Niehrs, C.4
  • 31
    • 0032578783 scopus 로고    scopus 로고
    • Molecular cloning and characterization of LR3, a novel LDL receptor family protein with mitogenic activity
    • Dong, Y., Lathrop, W., Weaver, D., Qiu, Q., Cini, J., Bertolini, D. and Chen, D. (1998). Molecular cloning and characterization of LR3, a novel LDL receptor family protein with mitogenic activity. Biochem. Biophys. Res. Commun. 251, 784-790.
    • (1998) Biochem. Biophys. Res. Commun. , vol.251 , pp. 784-790
    • Dong, Y.1    Lathrop, W.2    Weaver, D.3    Qiu, Q.4    Cini, J.5    Bertolini, D.6    Chen, D.7
  • 32
    • 0033577808 scopus 로고    scopus 로고
    • Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization
    • Fagotto, F., Jho, E., Zeng, L., Kurth, T., Joos, T., Kaufmann, C. and Costantini, F. (1999). Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization. J. Cell Biol. 145, 741-756.
    • (1999) J. Cell Biol. , vol.145 , pp. 741-756
    • Fagotto, F.1    Jho, E.2    Zeng, L.3    Kurth, T.4    Joos, T.5    Kaufmann, C.6    Costantini, F.7
  • 34
    • 0037422571 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion
    • Fujino, T., Asaba, H., Kang, M. J., Ikeda, Y., Sone, H., Takada, S., Kim, D. H., Ioka, R. X., Ono, M., Tomoyori, H. et al. (2003). Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion. Proc. Natl. Acad. Sci. USA 100, 229-234.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 229-234
    • Fujino, T.1    Asaba, H.2    Kang, M.J.3    Ikeda, Y.4    Sone, H.5    Takada, S.6    Kim, D.H.7    Ioka, R.X.8    Ono, M.9    Tomoyori, H.10
  • 35
    • 0032556910 scopus 로고    scopus 로고
    • Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
    • Glinka, A., Wu, W., Delius, H., Monaghan, A. P., Blumenstock, C. and Niehrs, C. (1998). Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 391, 357-362.
    • (1998) Nature , vol.391 , pp. 357-362
    • Glinka, A.1    Wu, W.2    Delius, H.3    Monaghan, A.P.4    Blumenstock, C.5    Niehrs, C.6
  • 37
    • 0034661718 scopus 로고    scopus 로고
    • A mode of regulation of beta-catenin signaling activity in Xenopus embryos independent of its levels
    • Guger, K. A. and Gumbiner, B. M. (2000). A mode of regulation of beta-catenin signaling activity in Xenopus embryos independent of its levels. Dev. Biol. 223, 441-448.
    • (2000) Dev. Biol. , vol.223 , pp. 441-448
    • Guger, K.A.1    Gumbiner, B.M.2
  • 38
    • 0037604557 scopus 로고    scopus 로고
    • A Wnt-Wnt situation
    • He, X. (2003). A Wnt-Wnt situation. Dev. Cell 4, 791-797.
    • (2003) Dev. Cell , vol.4 , pp. 791-797
    • He, X.1
  • 39
    • 0030941498 scopus 로고    scopus 로고
    • A member of the Frizzled protein family mediating axis induction by Wnt-5A
    • He, X., Saint-Jeannet, J. P., Wang, Y., Nathans, J., Dawid, I. and Varmus, H. (1997). A member of the Frizzled protein family mediating axis induction by Wnt-5A. Science 275, 1652-1654.
    • (1997) Science , vol.275 , pp. 1652-1654
    • He, X.1    Saint-Jeannet, J.P.2    Wang, Y.3    Nathans, J.4    Dawid, I.5    Varmus, H.6
  • 41
    • 0035997373 scopus 로고    scopus 로고
    • Lipoprotein receptors in the nervous system
    • Herz, J. and Bock, H. H. (2002). Lipoprotein receptors in the nervous system. Annu. Rev. Biochem. 71, 405-434.
    • (2002) Annu. Rev. Biochem. , vol.71 , pp. 405-434
    • Herz, J.1    Bock, H.H.2
  • 43
    • 0037144481 scopus 로고    scopus 로고
    • A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta-catenin-dependent signaling
    • Holmen, S. L., Salic, A., Zylstra, C. R., Kirschner, M. W. and Williams, B. O. (2002). A novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta-catenin-dependent signaling. J. Biol. Chem. 277, 34727-34735.
    • (2002) J. Biol. Chem. , vol.277 , pp. 34727-34735
    • Holmen, S.L.1    Salic, A.2    Zylstra, C.R.3    Kirschner, M.W.4    Williams, B.O.5
  • 44
    • 0036768107 scopus 로고    scopus 로고
    • Cloning and expression of Xenopus Lrp5 and Lrp6 genes
    • Houston, D. W. and Wylie, C. (2002). Cloning and expression of Xenopus Lrp5 and Lrp6 genes. Mech. Dev. 117, 337-342.
    • (2002) Mech. Dev. , vol.117 , pp. 337-342
    • Houston, D.W.1    Wylie, C.2
  • 45
    • 0033616573 scopus 로고    scopus 로고
    • Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein
    • Hsieh, J. C., Rattner, A., Smallwood, P. M. and Nathans, J. (1999). Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein. Proc. Natl. Acad. Sci. USA 96, 3546-3551.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 3546-3551
    • Hsieh, J.C.1    Rattner, A.2    Smallwood, P.M.3    Nathans, J.4
  • 47
    • 0032039482 scopus 로고    scopus 로고
    • The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities
    • Hsu, D. R., Economides, A. N., Wang, X., Eimon, P. M. and Harland, R. M. (1998). The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Mol. Cell 1, 673-683.
    • (1998) Mol. Cell , vol.1 , pp. 673-683
    • Hsu, D.R.1    Economides, A.N.2    Wang, X.3    Eimon, P.M.4    Harland, R.M.5
  • 48
    • 0033524929 scopus 로고    scopus 로고
    • Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain
    • Hsu, W., Zeng, L. and Costantini, F. (1999). Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain. J. Biol. Chem. 274, 3439-3445.
    • (1999) J. Biol. Chem. , vol.274 , pp. 3439-3445
    • Hsu, W.1    Zeng, L.2    Costantini, F.3
  • 49
    • 0036860704 scopus 로고    scopus 로고
    • The Wnt signalling pathway
    • Huelsken, J. and Behrens, J. (2002). The Wnt signalling pathway. J. Cell Sci. 115, 3977-3978.
    • (2002) J. Cell Sci. , vol.115 , pp. 3977-3978
    • Huelsken, J.1    Behrens, J.2
  • 51
    • 0033993931 scopus 로고    scopus 로고
    • Interaction of Dishevelled and Xenopus axin-related protein is required for Wnt signal transduction
    • Itoh, K., Antipova, A., Ratcliffe, M. J. and Sokol, S. (2000). Interaction of Dishevelled and Xenopus axin-related protein is required for Wnt signal transduction. Mol. Cell. Biol. 20, 2228-2238.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 2228-2238
    • Itoh, K.1    Antipova, A.2    Ratcliffe, M.J.3    Sokol, S.4
  • 52
    • 0035013711 scopus 로고    scopus 로고
    • Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair
    • Jeon, H., Meng, W., Takagi, J., Eck, M. J., Springer, T. A. and Blacklow, S. C. (2001). Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair. Nat. Struct. Biol. 8, 499-504.
    • (2001) Nat. Struct. Biol. , vol.8 , pp. 499-504
    • Jeon, H.1    Meng, W.2    Takagi, J.3    Eck, M.J.4    Springer, T.A.5    Blacklow, S.C.6
  • 53
    • 0036148208 scopus 로고    scopus 로고
    • Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
    • Jho, E. H., Zhang, T., Domon, C., Joo, C. K., Freund, J. N. and Costantini, F. (2002). Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol. Cell Biol. 22, 1172-1183.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 1172-1183
    • Jho, E.H.1    Zhang, T.2    Domon, C.3    Joo, C.K.4    Freund, J.N.5    Costantini, F.6
  • 54
    • 0037092049 scopus 로고    scopus 로고
    • Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor
    • Kato, M., Patel, M. S., Levasseur, R., Lobov, I., Chang, B. H., Glass, D. A., 2nd, Hartmann, C., Li, L., Hwang, T. H., Brayton, C. F. et al. (2002). Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor. J. Cell Biol. 157, 303-314.
    • (2002) J. Cell Biol. , vol.157 , pp. 303-314
    • Kato, M.1    Patel, M.S.2    Levasseur, R.3    Lobov, I.4    Chang, B.H.5    Glass II, D.A.6    Hartmann, C.7    Li, L.8    Hwang, T.H.9    Brayton, C.F.10
  • 55
    • 2342441840 scopus 로고    scopus 로고
    • Wnt co-receptors, Lrp5 and Lrp6, are essential for gastrulation in mice
    • (in press)
    • Kelly, O. G., Pinson, K. I. and Skarnes, W. C. (2004). Wnt co-receptors, Lrp5 and Lrp6, are essential for gastrulation in mice. Development (in press).
    • (2004) Development
    • Kelly, O.G.1    Pinson, K.I.2    Skarnes, W.C.3
  • 56
    • 0032443021 scopus 로고    scopus 로고
    • Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway
    • Kennerdell, J. R. and Carthew, R. W. (1998). Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway. Cell 95, 1017-1026.
    • (1998) Cell , vol.95 , pp. 1017-1026
    • Kennerdell, J.R.1    Carthew, R.W.2
  • 57
    • 0033194431 scopus 로고    scopus 로고
    • Modulation of Wnt signaling by Axin and Axil
    • Kikuchi, A. (1999). Modulation of Wnt signaling by Axin and Axil. Cytokine Growth Factor Rev. 10, 255-265.
    • (1999) Cytokine Growth Factor Rev. , vol.10 , pp. 255-265
    • Kikuchi, A.1
  • 58
    • 0032446373 scopus 로고    scopus 로고
    • A new low density lipoprotein receptor related protein, LRP5, is expressed in hepatocytes and adrenal cortex, and recognizes apolipoprotein E
    • Kim, D. H., Inagaki, Y., Suzuki, T., Ioka, R. X., Yoshioka, S. Z., Magoori, K., Kang, M. J., Cho, Y., Nakano, A. Z., Liu, Q. et al. (1998). A new low density lipoprotein receptor related protein, LRP5, is expressed in hepatocytes and adrenal cortex, and recognizes apolipoprotein E. J. Biochem (Tokyo) 124, 1072-1076.
    • (1998) J. Biochem. (Tokyo) , vol.124 , pp. 1072-1076
    • Kim, D.H.1    Inagaki, Y.2    Suzuki, T.3    Ioka, R.X.4    Yoshioka, S.Z.5    Magoori, K.6    Kang, M.J.7    Cho, Y.8    Nakano, A.Z.9    Liu, Q.10
  • 60
    • 0033011602 scopus 로고    scopus 로고
    • DIX domains of Dv1 and axin are necessary for protein interactions and their ability to regulate beta-catenin stability
    • Kishida, S., Yamamoto, H., Hino, S., Ikeda, S., Kishida, M. and Kikuchi, A. (1999b). DIX domains of Dv1 and axin are necessary for protein interactions and their ability to regulate beta-catenin stability. Mol. Cell. Biol. 19, 4414-4422.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 4414-4422
    • Kishida, S.1    Yamamoto, H.2    Hino, S.3    Ikeda, S.4    Kishida, M.5    Kikuchi, A.6
  • 61
    • 0036714030 scopus 로고    scopus 로고
    • Canonical and non-canonical Wnt signaling pathways in Caenorhabditis elegans: Variations on a common signaling theme
    • Korswagen, H. C. (2002). Canonical and non-canonical Wnt signaling pathways in Caenorhabditis elegans: variations on a common signaling theme. BioEssays 24, 801-810.
    • (2002) BioEssays , vol.24 , pp. 801-810
    • Korswagen, H.C.1
  • 62
  • 63
    • 0037023584 scopus 로고    scopus 로고
    • Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex
    • Kramps, T., Peter, O., Brunner, E., Nellen, D., Froesch, B., Chatterjee, S., Murone, M., Zullig, S. and Basler, K. (2002). Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. Cell 109, 47-60.
    • (2002) Cell , vol.109 , pp. 47-60
    • Kramps, T.1    Peter, O.2    Brunner, E.3    Nellen, D.4    Froesch, B.5    Chatterjee, S.6    Murone, M.7    Zullig, S.8    Basler, K.9
  • 65
    • 0038267120 scopus 로고    scopus 로고
    • Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity
    • Kusu, N., Laurikkala, J., Imanishi, M., Usui, H., Konishi, M., Miyake, A., Thesleff, I. and Itoh, N. (2003). Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity. J. Biol. Chem. 278, 24113-24117.
    • (2003) J. Biol. Chem. , vol.278 , pp. 24113-24117
    • Kusu, N.1    Laurikkala, J.2    Imanishi, M.3    Usui, H.4    Konishi, M.5    Miyake, A.6    Thesleff, I.7    Itoh, N.8
  • 66
    • 0242521297 scopus 로고    scopus 로고
    • Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot
    • Laurikkala, J., Kassai, Y., Pakkasjärvi, L., Thesleff, I. and Itoh, N. (2003). Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot. Dev. Biol. 264, 91-105.
    • (2003) Dev. Biol. , vol.264 , pp. 91-105
    • Laurikkala, J.1    Kassai, Y.2    Pakkasjärvi, L.3    Thesleff, I.4    Itoh, N.5
  • 67
    • 4243067196 scopus 로고    scopus 로고
    • The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway
    • Lee, E., Salic, A., Kruger, R., Heinrich, R. and Kirschner, M. W. (2003). The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. PLoS Biol. 1, E10.
    • (2003) PLoS Biol. , vol.1
    • Lee, E.1    Salic, A.2    Kruger, R.3    Heinrich, R.4    Kirschner, M.W.5
  • 68
    • 0037077266 scopus 로고    scopus 로고
    • Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling
    • Leung, J. Y., Kolligs, F. T., Wu, R., Zhai, Y., Kuick, R., Hanash, S., Cho, K. R. and Fearon, E. R. (2002). Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling. J. Biol. Chem. 277, 21657-21665.
    • (2002) J. Biol. Chem. , vol.277 , pp. 21657-21665
    • Leung, J.Y.1    Kolligs, F.T.2    Wu, R.3    Zhai, Y.4    Kuick, R.5    Hanash, S.6    Cho, K.R.7    Fearon, E.R.8
  • 69
    • 0033517102 scopus 로고    scopus 로고
    • Axin and Frat1 interact with dv1 and GSK, bridging Dv1 to GSK in Wnt-mediated regulation of LEF-1
    • Li, L., Yuan, H., Weaver, C. D., Mao, J., Farr, G. H., 3rd, Sussman, D. J., Jonkers, J., Kimelman, D. and Wu, D. (1999). Axin and Frat1 interact with dv1 and GSK, bridging Dv1 to GSK in Wnt-mediated regulation of LEF-1. EMBO J. 18, 4233-4240.
    • (1999) EMBO J. , vol.18 , pp. 4233-4240
    • Li, L.1    Yuan, H.2    Weaver, C.D.3    Mao, J.4    Farr III, G.H.5    Sussman, D.J.6    Jonkers, J.7    Kimelman, D.8    Wu, D.9
  • 70
    • 0037155185 scopus 로고    scopus 로고
    • Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled
    • Li, L., Mao, J., Sun, L., Liu, W. and Wu, D. (2002). Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled. J. Biol. Chem. 277, 5977-5981.
    • (2002) J. Biol. Chem. , vol.277 , pp. 5977-5981
    • Li, L.1    Mao, J.2    Sun, L.3    Liu, W.4    Wu, D.5
  • 72
    • 0042131956 scopus 로고    scopus 로고
    • A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor
    • Liu, G., Bafico, A., Harris, V. K. and Aaronson, S. A. (2003). A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor. Mol. Cell. Biol. 23, 5825-5835.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 5825-5835
    • Liu, G.1    Bafico, A.2    Harris, V.K.3    Aaronson, S.A.4
  • 75
    • 2342436339 scopus 로고    scopus 로고
    • Hypomorphic expression of Dkk1 in the doubleridge mouse: Dosage dependence and compensatory interactions with Lrp6
    • (in press)
    • MacDonald, B. T., Adamska, M. and Meisler, M. H. (2004). Hypomorphic expression of Dkk1 in the doubleridge mouse: dosage dependence and compensatory interactions with Lrp6. Development (in press).
    • (2004) Development
    • MacDonald, B.T.1    Adamska, M.2    Meisler, M.H.3
  • 76
    • 0038515322 scopus 로고    scopus 로고
    • Severe hypercholesterolemia, impaired fat tolerance and advanced atherosclerosis in mice lacking both LDL receptor-related protein 5 (LRP5) and apolipoprotein E
    • Magoori, K., Kang, M. J., Ito, M. R., Kakuuchi, H., Ioka, R. X., Kamataki, A., Kim, D. H., Asaba, H., Iwasaki, S., Takei, Y. A. et al. (2003). Severe hypercholesterolemia, impaired fat tolerance and advanced atherosclerosis in mice lacking both LDL receptor-related protein 5 (LRP5) and apolipoprotein E. J. Biol. Chem. 278, 11331-11336.
    • (2003) J. Biol. Chem. , vol.278 , pp. 11331-11336
    • Magoori, K.1    Kang, M.J.2    Ito, M.R.3    Kakuuchi, H.4    Ioka, R.X.5    Kamataki, A.6    Kim, D.H.7    Asaba, H.8    Iwasaki, S.9    Takei, Y.A.10
  • 77
    • 0035964862 scopus 로고    scopus 로고
    • Wnt signaling and heterotrimeric G-proteins: Strange bedfellows or a classic romance?
    • Malbon, C. C., Wang, H. and Moon, R. T. (2001). Wnt signaling and heterotrimeric G-proteins: strange bedfellows or a classic romance? Biochem. Biophys. Res. Commun. 287, 589-593.
    • (2001) Biochem. Biophys. Res. Commun. , vol.287 , pp. 589-593
    • Malbon, C.C.1    Wang, H.2    Moon, R.T.3
  • 78
    • 0037413696 scopus 로고    scopus 로고
    • Kremen2 modulates Dickkopf2 activity during Wnt/lRP6 signaling
    • Mao, B. and Niehrs, C. (2003). Kremen2 modulates Dickkopf2 activity during Wnt/lRP6 signaling. Gene 302, 179-183.
    • (2003) Gene , vol.302 , pp. 179-183
    • Mao, B.1    Niehrs, C.2
  • 79
    • 0035902050 scopus 로고    scopus 로고
    • LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
    • Mao, B., Wu, W., Li, Y., Hoppe, D., Stannek, P., Glinka, A. and Niehrs, C. (2001a). LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 411, 321-325.
    • (2001) Nature , vol.411 , pp. 321-325
    • Mao, B.1    Wu, W.2    Li, Y.3    Hoppe, D.4    Stannek, P.5    Glinka, A.6    Niehrs, C.7
  • 81
    • 18244427021 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
    • Mao, J., Wang, J., Liu, B., Pan, W., Farr, G. H., 3rd, Flynn, C., Yuan, H., Takada, S., Kimelman, D., Li, L. et al. (2001b). Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol. Cell 7, 801-809.
    • (2001) Mol. Cell , vol.7 , pp. 801-809
    • Mao, J.1    Wang, J.2    Liu, B.3    Pan, W.4    Farr III, G.H.5    Flynn, C.6    Yuan, H.7    Takada, S.8    Kimelman, D.9    Li, L.10
  • 84
    • 0033040240 scopus 로고    scopus 로고
    • Wingless signaling in the Drosophila embryo: Zygotic requirements and the role of the frizzled genes
    • Muller, H., Samanta, R. and Wieschaus, E. (1999). Wingless signaling in the Drosophila embryo: zygotic requirements and the role of the frizzled genes. Development 126, 577-586.
    • (1999) Development , vol.126 , pp. 577-586
    • Muller, H.1    Samanta, R.2    Wieschaus, E.3
  • 85
    • 0030864520 scopus 로고    scopus 로고
    • A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family
    • Niebuhr, K., Ebel, F., Frank, R., Reinhard, M., Domann, E., Carl, U. D., Walter, U., Gertler, F. B., Wehland, J. and Chakraborty, T. (1997). A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family. EMBO J. 16, 5433-5444.
    • (1997) EMBO J. , vol.16 , pp. 5433-5444
    • Niebuhr, K.1    Ebel, F.2    Frank, R.3    Reinhard, M.4    Domann, E.5    Carl, U.D.6    Walter, U.7    Gertler, F.B.8    Wehland, J.9    Chakraborty, T.10
  • 86
    • 0033180030 scopus 로고    scopus 로고
    • Head in the WNT: The molecular nature of Spemann's head organizer
    • Niehrs, C. (1999). Head in the WNT: the molecular nature of Spemann's head organizer. Trends Genet. 15, 314-319.
    • (1999) Trends Genet. , vol.15 , pp. 314-319
    • Niehrs, C.1
  • 87
    • 0344464720 scopus 로고    scopus 로고
    • Wnts and Hedgehogs: Lipid-modified proteins and similarities in signaling mechanisms at the cell surface
    • Nusse, R. (2003). Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface. Development 130, 5297-5305.
    • (2003) Development , vol.130 , pp. 5297-5305
    • Nusse, R.1
  • 88
    • 0020216124 scopus 로고
    • Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
    • Nusse, R. and Varmus, H. E. (1982). Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell 31, 99-109.
    • (1982) Cell , vol.31 , pp. 99-109
    • Nusse, R.1    Varmus, H.E.2
  • 89
    • 0037313644 scopus 로고    scopus 로고
    • Wnts and TGF beta in synaptogenesis: Old friends signalling at new places
    • Packard, M., Mathew, D. and Budnik, V. (2003). Wnts and TGF beta in synaptogenesis: old friends signalling at new places. Nat. Rev. Neurosci. 4, 113-120.
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 113-120
    • Packard, M.1    Mathew, D.2    Budnik, V.3
  • 90
    • 0036333382 scopus 로고    scopus 로고
    • Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila
    • Parker, D. S., Jemison, J. and Cadigan, K. M. (2002). Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila. Development 129, 2565-2576.
    • (2002) Development , vol.129 , pp. 2565-2576
    • Parker, D.S.1    Jemison, J.2    Cadigan, K.M.3
  • 91
    • 0037118279 scopus 로고    scopus 로고
    • Regulation of bone formation and vision by LRP5
    • Patel, M. S. and Karsenty, G. (2002). Regulation of bone formation and vision by LRP5. New Engl. J. Med. 346, 1572-1574.
    • (2002) New Engl. J. Med. , vol.346 , pp. 1572-1574
    • Patel, M.S.1    Karsenty, G.2
  • 92
    • 0031457622 scopus 로고    scopus 로고
    • Signaling through scaffold, anchoring, and adaptor proteins
    • Pawson, T. and Scott, J. D. (1997). Signaling through scaffold, anchoring, and adaptor proteins. Science 278, 2075-2080.
    • (1997) Science , vol.278 , pp. 2075-2080
    • Pawson, T.1    Scott, J.D.2
  • 93
    • 0037453510 scopus 로고    scopus 로고
    • Assembly of cell regulatory systems through protein interaction domains
    • Pawson, T. and Nash, P. (2003). Assembly of cell regulatory systems through protein interaction domains. Science 300, 445-452.
    • (2003) Science , vol.300 , pp. 445-452
    • Pawson, T.1    Nash, P.2
  • 94
    • 0033135571 scopus 로고    scopus 로고
    • A mouse cerberus/Dan-related gene family
    • Pearce, J. J., Penny, G. and Rossant, J. (1999). A mouse cerberus/Dan-related gene family. Dev. Biol. 209, 98-110.
    • (1999) Dev. Biol. , vol.209 , pp. 98-110
    • Pearce, J.J.1    Penny, G.2    Rossant, J.3
  • 96
    • 0034727078 scopus 로고    scopus 로고
    • An LDL-receptor-related protein mediates Wnt signalling in mice
    • Pinson, K. I., Brennan, J., Monkley, S., Avery, B. J. and Skarnes, W. C. (2000). An LDL-receptor-related protein mediates Wnt signalling in mice. Nature 407, 535-538.
    • (2000) Nature , vol.407 , pp. 535-538
    • Pinson, K.I.1    Brennan, J.2    Monkley, S.3    Avery, B.J.4    Skarnes, W.C.5
  • 97
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis, P. (2000). Wnt signaling and cancer. Genes Dev. 14, 1837-1851.
    • (2000) Genes Dev. , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 98
    • 0037162282 scopus 로고    scopus 로고
    • Casein kinase 1: A Wnt'er of disconnect
    • Polakis, P. (2002). Casein kinase 1: a Wnt'er of disconnect. Curr. Biol. 12, R499-R501.
    • (2002) Curr. Biol. , vol.12
    • Polakis, P.1
  • 101
    • 0242690871 scopus 로고    scopus 로고
    • Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis
    • Rothbacher, U., Laurent, M. N., Deardorff, M. A., Klein, P. S., Cho, K. W. and Fraser, S. E. (2000). Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis. EMBO J. 19, 1010-1022.
    • (2000) EMBO J. , vol.19 , pp. 1010-1022
    • Rothbacher, U.1    Laurent, M.N.2    Deardorff, M.A.3    Klein, P.S.4    Cho, K.W.5    Fraser, S.E.6
  • 103
    • 0027533916 scopus 로고
    • Functional significance of a family of protein kinases encoded at the shaggy locus in Drosophila
    • Ruel, L., Pantesco, V., Lutz, Y., Simpson, P. and Bourouis, M. (1993). Functional significance of a family of protein kinases encoded at the shaggy locus in Drosophila. EMBO J. 12, 1657-1669.
    • (1993) EMBO J. , vol.12 , pp. 1657-1669
    • Ruel, L.1    Pantesco, V.2    Lutz, Y.3    Simpson, P.4    Bourouis, M.5
  • 104
    • 0033636247 scopus 로고    scopus 로고
    • Pathway specificity by the bifunctional receptor frizzled is determined by affinity for wingless
    • Rulifson, E. J., Wu, C. H. and Nusse, R. (2000). Pathway specificity by the bifunctional receptor frizzled is determined by affinity for wingless. Mol. Cell 6, 117-126.
    • (2000) Mol. Cell , vol.6 , pp. 117-126
    • Rulifson, E.J.1    Wu, C.H.2    Nusse, R.3
  • 105
    • 0033714885 scopus 로고    scopus 로고
    • Control of beta-catenin stability: Reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts
    • Salic, A., Lee, E., Mayer, L. and Kirschner, M. W. (2000). Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts. Mol. Cell 5, 523-532.
    • (2000) Mol. Cell , vol.5 , pp. 523-532
    • Salic, A.1    Lee, E.2    Mayer, L.3    Kirschner, M.W.4
  • 106
    • 0029814396 scopus 로고    scopus 로고
    • The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein similar to the Drosophila frizzled protein
    • Sawa, H., Lobel, L. and Horvitz, H. R. (1996). The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein similar to the Drosophila frizzled protein. Genes Dev. 10, 2189-2197.
    • (1996) Genes Dev. , vol.10 , pp. 2189-2197
    • Sawa, H.1    Lobel, L.2    Horvitz, H.R.3
  • 107
    • 0037102507 scopus 로고    scopus 로고
    • The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling
    • Schwarz-Romond, T., Asbrand, C., Bakkers, J., Kuhl, M., Schaeffer, H. J., Huelsken, J., Behrens, J., Hammerschmidt, M. and Birchmeier, W. (2002). The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. Genes Dev. 16, 2073-2084.
    • (2002) Genes Dev. , vol.16 , pp. 2073-2084
    • Schwarz-Romond, T.1    Asbrand, C.2    Bakkers, J.3    Kuhl, M.4    Schaeffer, H.J.5    Huelsken, J.6    Behrens, J.7    Hammerschmidt, M.8    Birchmeier, W.9
  • 108
    • 0242704649 scopus 로고    scopus 로고
    • Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors
    • Schweizer, L. and Varmus, H. (2003). Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors. BMC Cell Biol. 4, 4.
    • (2003) BMC Cell Biol. , vol.4 , pp. 4
    • Schweizer, L.1    Varmus, H.2
  • 109
    • 2342428366 scopus 로고    scopus 로고
    • Secreted antagonists/modulators of Wnt signaling
    • (ed. M. Kuhl), Geogetown, TX: Landers Bioscience
    • Semenov, M. and He, X. (2003). Secreted antagonists/modulators of Wnt signaling. In Wnt Signaling in Development (ed. M. Kuhl), pp. 16-25. Geogetown, TX: Landers Bioscience.
    • (2003) Wnt Signaling in Development , pp. 16-25
    • Semenov, M.1    He, X.2
  • 110
    • 0035954281 scopus 로고    scopus 로고
    • Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6
    • Semenov, M. V., Tamai, K., Brott, B. K., Kuhl, M., Sokol, S. and He, X. (2001). Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Curr. Biol. 11, 951-961.
    • (2001) Curr. Biol. , vol.11 , pp. 951-961
    • Semenov, M.V.1    Tamai, K.2    Brott, B.K.3    Kuhl, M.4    Sokol, S.5    He, X.6
  • 112
    • 0036838737 scopus 로고    scopus 로고
    • Uterine sensitization-associated gene-1: A novel gene induced within the rat endometrium at the time of uterine receptivity/sensitization for the decidual cell reaction
    • Simmons, D. G. and Kennedy, T. G. (2002). Uterine sensitization-associated gene-1: a novel gene induced within the rat endometrium at the time of uterine receptivity/sensitization for the decidual cell reaction. Biol. Reprod. 67, 1638-1645.
    • (2002) Biol. Reprod. , vol.67 , pp. 1638-1645
    • Simmons, D.G.1    Kennedy, T.G.2
  • 114
    • 0032491379 scopus 로고    scopus 로고
    • An extracellular beta-propeller module predicted in lipoprotein and scavenger receptors, tyrosine kinases, epidermal growth factor precursor, and extracellular matrix components
    • Springer, T. A. (1998). An extracellular beta-propeller module predicted in lipoprotein and scavenger receptors, tyrosine kinases, epidermal growth factor precursor, and extracellular matrix components. J. Mol. Biol. 283, 837-862.
    • (1998) J. Mol. Biol. , vol.283 , pp. 837-862
    • Springer, T.A.1
  • 115
    • 0142042539 scopus 로고    scopus 로고
    • Frizzled signalling and cell polarisation in Drosophila and vertebrates
    • Strutt, D. (2003). Frizzled signalling and cell polarisation in Drosophila and vertebrates. Development 130, 4501-4513.
    • (2003) Development , vol.130 , pp. 4501-4513
    • Strutt, D.1
  • 116
    • 0034130385 scopus 로고    scopus 로고
    • Xwnt11 is a target of Xenopus Brachyury: Regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway
    • Tada, M. and Smith, J. C. (2000). Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway. Development 127, 2227-2238.
    • (2000) Development , vol.127 , pp. 2227-2238
    • Tada, M.1    Smith, J.C.2
  • 120
    • 0030747773 scopus 로고    scopus 로고
    • Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm
    • Thorpe, C. J., Schlesinger, A., Carter, J. C. and Bowerman, B. (1997). Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm. Cell 90, 695-705.
    • (1997) Cell , vol.90 , pp. 695-705
    • Thorpe, C.J.1    Schlesinger, A.2    Carter, J.C.3    Bowerman, B.4
  • 121
    • 19344371404 scopus 로고    scopus 로고
    • A nuclear function for Armadillo/β-catenin
    • (in press)
    • Tolwinski, N. S. and Wieschaus, E. (2004). A nuclear function for Armadillo/β-catenin. PLoS Biol. (in press).
    • (2004) PLoS Biol.
    • Tolwinski, N.S.1    Wieschaus, E.2
  • 122
    • 0034960921 scopus 로고    scopus 로고
    • Armadillo nuclear import is regulated by cytoplasmic anchor Axin and nuclear anchor dTCF/Pan
    • Tolwinski, N. S. and Wieschaus, E. (2001). Armadillo nuclear import is regulated by cytoplasmic anchor Axin and nuclear anchor dTCF/Pan. Development 128, 2107-2117.
    • (2001) Development , vol.128 , pp. 2107-2117
    • Tolwinski, N.S.1    Wieschaus, E.2
  • 123
    • 0037343952 scopus 로고    scopus 로고
    • Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity
    • Tolwinski, N. S., Wehrli, M., Rives, A., Erdeniz, N., DiNardo, S. and Wieschaus, E. (2003). Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity. Dev. Cell 4, 407-418.
    • (2003) Dev. Cell , vol.4 , pp. 407-418
    • Tolwinski, N.S.1    Wehrli, M.2    Rives, A.3    Erdeniz, N.4    DiNardo, S.5    Wieschaus, E.6
  • 125
    • 0035893281 scopus 로고    scopus 로고
    • Chromatin-specific regulation of LEF-1-beta-catenin transcription activation and inhibition in vitro
    • Tutter, A. V., Fryer, C. J. and Jones, K. A. (2001). Chromatin-specific regulation of LEF-1-beta-catenin transcription activation and inhibition in vitro. Genes Dev. 15, 3342-3354.
    • (2001) Genes Dev. , vol.15 , pp. 3342-3354
    • Tutter, A.V.1    Fryer, C.J.2    Jones, K.A.3
  • 126
    • 0034665045 scopus 로고    scopus 로고
    • The C-terminal cytoplasmic Lys-thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signalling
    • Umbhauer, M., Djiane, A., Goisset, C., Penzo-Mendez, A., Riou, J. F., Boucaut, J. C. and Shi, D. L. (2000). The C-terminal cytoplasmic Lys-thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signalling. EMBO J. 19, 4944-4954.
    • (2000) EMBO J. , vol.19 , pp. 4944-4954
    • Umbhauer, M.1    Djiane, A.2    Goisset, C.3    Penzo-Mendez, A.4    Riou, J.F.5    Boucaut, J.C.6    Shi, D.L.7
  • 128
    • 0041695485 scopus 로고    scopus 로고
    • A second canon. Functions and mechanisnis of beta-catenin-independent Wnt signaling
    • Veeman, M. T., Axelrod, J. D. and Moon, R. T. (2003). A second canon. Functions and mechanisnis of beta-catenin-independent Wnt signaling. Dev. Cell 5, 367-377.
    • (2003) Dev. Cell , vol.5 , pp. 367-377
    • Veeman, M.T.1    Axelrod, J.D.2    Moon, R.T.3
  • 131
    • 0037229938 scopus 로고    scopus 로고
    • Runnin' with the Dvl: Proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction
    • Wharton, K. A., Jr (2003). Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction. Dev. Biol. 253, 1-17.
    • (2003) Dev. Biol. , vol.253 , pp. 1-17
    • Wharton Jr., K.A.1
  • 132
    • 0033565533 scopus 로고    scopus 로고
    • Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex
    • Willert, K., Shibamoto, S. and Nusse, R. (1999). Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex. Genes Dev. 13, 1768-1773.
    • (1999) Genes Dev. , vol.13 , pp. 1768-1773
    • Willert, K.1    Shibamoto, S.2    Nusse, R.3
  • 134
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signaling in development
    • Wodarz, A. and Nusse, R. (1998). Mechanisms of Wnt signaling in development. Annu. Rev. Cell Dev. Biol. 14, 59-88.
    • (1998) Annu. Rev. Cell Dev. Biol. , vol.14 , pp. 59-88
    • Wodarz, A.1    Nusse, R.2
  • 135
    • 0344413477 scopus 로고    scopus 로고
    • Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled
    • Wong, H. C., Bourdelas, A., Krauss, A., Lee, H. J., Shao, Y., Wu, D., Mlodzik, M., Shi, D. L. and Zheng, J. (2003). Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled. Mol. Cell 12, 1251-1260.
    • (2003) Mol. Cell , vol.12 , pp. 1251-1260
    • Wong, H.C.1    Bourdelas, A.2    Krauss, A.3    Lee, H.J.4    Shao, Y.5    Wu, D.6    Mlodzik, M.7    Shi, D.L.8    Zheng, J.9
  • 136
    • 0036830126 scopus 로고    scopus 로고
    • Ligand receptor interactions in the Wnt signaling pathway in Drosophila
    • Wu, C. H. and Nusse, R. (2002). Ligand receptor interactions in the Wnt signaling pathway in Drosophila. J. Biol. Chem. 277, 41762-41769.
    • (2002) J. Biol. Chem. , vol.277 , pp. 41762-41769
    • Wu, C.H.1    Nusse, R.2
  • 137
    • 1542375163 scopus 로고    scopus 로고
    • Ozz: A new name on the long list of β-catenin's nemeses
    • Wu, G., Liu, C. and He, X. (2004). Ozz: a new name on the long list of β-catenin's nemeses. Mol. Cell 13, 451-453.
    • (2004) Mol. Cell , vol.13 , pp. 451-453
    • Wu, G.1    Liu, C.2    He, X.3
  • 138
    • 0034649592 scopus 로고    scopus 로고
    • Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling
    • Wu, W., Glinka, A., Delius, H. and Niehrs, C. (2000). Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling. Curr. Biol. 10, 1611-1614.
    • (2000) Curr. Biol. , vol.10 , pp. 1611-1614
    • Wu, W.1    Glinka, A.2    Delius, H.3    Niehrs, C.4
  • 139
    • 0031943002 scopus 로고    scopus 로고
    • Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos
    • Yamamoto, H., Kishida, S., Uochi, T., Ikeda, S., Koyama, S., Asashima, M. and Kikuchi, A. (1999). Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos. Mol. Cell. Biol. 18, 2867-2875.
    • (1999) Mol. Cell Biol. , vol.18 , pp. 2867-2875
    • Yamamoto, H.1    Kishida, S.2    Uochi, T.3    Ikeda, S.4    Koyama, S.5    Asashima, M.6    Kikuchi, A.7
  • 140
    • 0033574527 scopus 로고    scopus 로고
    • Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability
    • Yamamoto, H., Kishida, S., Kishida, M., Ikeda, S., Takada, S. and Kikuchi, A. (1999). Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability. J. Biol. Chem. 274, 10681-10684.
    • (1999) J. Biol. Chem. , vol.274 , pp. 10681-10684
    • Yamamoto, H.1    Kishida, S.2    Kishida, M.3    Ikeda, S.4    Takada, S.5    Kikuchi, A.6
  • 142
    • 0030265570 scopus 로고    scopus 로고
    • A frizzled homolog functions in a vertebrate Wnt signaling pathway
    • Yang-Snyder, J., Miller, J. R., Brown, J. D., Lai, C. J. and Moon, R. T. (1996). A frizzled homolog functions in a vertebrate Wnt signaling pathway. Curr. Biol. 6, 1302-1306.
    • (1996) Curr. Biol. , vol.6 , pp. 1302-1306
    • Yang-Snyder, J.1    Miller, J.R.2    Brown, J.D.3    Lai, C.J.4    Moon, R.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.