Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila

Development

Volumn 129, Issue 11, 2002, Pages 2565-2576

  Parker, David S ^a   Jemison, Jemileh ^a   Cadigan, Kenneth M ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

catenin; Armadillo; Drosophila; TCF; Wingless; Wnt

Indexed keywords

GLYCOPROTEIN; HIGH MOBILITY GROUP PROTEIN; MUTANT PROTEIN; NUCLEAR PROTEIN; PROTEIN YGOPUS; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL CELL; ARMADILLO; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CHROMATIN; COMPLEX FORMATION; CONTROLLED STUDY; DATA ANALYSIS; DROSOPHILA; EPISTASIS; FEMALE; HETEROLOGOUS EXPRESSION; INSECT DEVELOPMENT; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ARMADILLO DOMAIN PROTEINS; CARRIER PROTEINS; CELL NUCLEUS; CELLS, CULTURED; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GREEN FLUORESCENT PROTEINS; HIGH MOBILITY GROUP PROTEINS; INSECT PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUMINESCENT PROTEINS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION;

ANIMALIA; ARACHNIDA; ARMADILLO; EUKARYOTA; HEXAPODA; INSECTA; MAMMALIA;

EID: 0036333382     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (79)

1. The PHD finger: Implications for chromatin-mediated transcriptional regulation
2. Drosophila CBP is required for dorsal-dependent twist gene expression
3. The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation
4. Pontin52, an interaction partner of beta-catenin, binds to the TATA box binding protein
5. Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity
6. A new member of the frizzled family from Drosophila functions as a Wingless receptor
7. Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development
8. An extensive 3′ cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-beta family in Drosophila
9. Antagonistic interactions between wingless and decapentaplegic responsible for dorsal-ventral pattern in the Drosophila Leg
10. Pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila
11. Wingless signaling in the Drosophila eye and embryonic epidermis
12. Wnt signaling: A common theme in animal development
13. Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing
14. Solution structure of the PHD domain from the KAP-1 corepressor: Structural determinants for PHD, RING and LIM zinc-binding domains
15. Drosophila Tcf and Groucho interact to repress Wingless signalling activity
16. The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster
17. Neuroblast specification and formation regulated by wingless in the Drosophila CNS
18. Osa-containing Brahma chromatin remodeling complexes are required for the repression of wingless target genes
19. The wingless signalling pathway and the patterning of the wing margin in Drosophila
20. Roles of the C terminus of Armadillo in Wingless signaling in Drosophila
21. The relative expression amounts of apterous and its co-factor dLdb/Chip are critical for dorso-ventral compartmentalization in the Drosophila wing
22. Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye
23. EGF receptor/Rolled MAP kinase signalling protects cells against activated Armadillo in the Drosophila eye
24. Ras pathway specificity is determined by the integration of multiple signal-activated and fissue-restricted transcription factors
25. Negative regulation of Wingless signaling by D-axin, a Drosophila homolog of axin
26. Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro
27. The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates
28. Distinct pathways for autocrine and paracrine Wingless signalling in Drosophila embryos
29. Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin
30. Complementary and mutually exclusive activities of decapentaplegic and wingless organize axial patterning during Drosophila leg development
31. Molecular integration of inductive and mesoderm-intrinsic inputs governs even-skipped enhancer activity in a subset of pericardial and dorsal muscle progenitors
32. Activation and repression of wingless/Wnt target genes by the TCF/LEF-1 family of transcription factors
33. Eye specification in Drosophila: Perspectives and implications
34. The role of Wingless signaling in establishing the anteroposterior and dorsoventral axes of the eye disc
35. Axin and Frat1 interact with dv1 and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1
36. Biochemical analyses of the AF10 protein: The extended LAP/PHD-finger mediates oligomerisation
37. Chromatin silencing and activation by Polycomb and trithorax group proteins
38. Normal stoichiometry of histone dimer sets is necessary for high fidelity of mitotic chromosome transmission
39. Regulation of Lef-mediated transcription and p53-dependent pathway by associating beta-catenin with CBP/p300
40. XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
41. Long-range action of Wingless organizes the dorsal-ventral axis of the Drosophila wing
42. Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila
43. Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in Drosophila
44. Mutations affecting segment number and polarity in Drosophila
45. Polycomblike PHD fingers mediate conserved interaction with Enhancer of Zeste protein
46. Negative regulation of Armadillo, a Wingless effector in Drosophila
47. Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins
48. Structure of the PHD zinc finger from human Williams-Beuren syndrome transcription factor
49. Wnt signaling in oncogenesis and embryogenesis - A look outside the nucleus
50. The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation
51. Wingless expression mediates determination of peripheral nervous system elements in late stages of Drosophila wing disc development
52. Induction of Drosophila eye development by decapentaplegic
53. Wnt signaling and cancer
54. A stable genomic source of P element transposase in Drosophila melanogaster
55. A modular misexpression screen in Drosophila detecting tissue-specific phenotypes
56. Systematic gain-of-function genetics in Drosophila
57. Wingless refines its own expression domain on the Drosophila wing margin
58. Control of beta-catenin stability: Reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts
59. The rough deal protein is a new kinetochore component required for accurate chromosome segregation in Drosophila
60. Overexpression of zeste white 3 blocks wingless signaling in the Drosophila embryonic midgut
61. Chloroplast division and morphology are differentially affected by overexpression of FtsZ1 and FtsZ2 genes in Arabidopsis
62. Regulation of β-catenin transformation by the p300 transcriptional coactivator
63. The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression
64. Developmental territories created by mutual antagonism between Wingless and Decapentaplegic
65. Armadillo nuclear import is regulated by cytoplasmic anchor Axin and nuclear anchor dTCF/Pan
66. Eyelid antagonizes wingless signaling during Drosophila development and has homology to the Bright family of DNA-binding proteins
67. Chromatin remodeling and transcriptional activation: The cast (in order of appearance)
68. Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF
69. Cell patterning in the Drosophila segment: Engrailed and wingless antigen distributions in segment polarity mutant embryos
70. Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling
71. A Drosophila Axin homolog, Daxin, inhibits Wnt signaling
72. Beta-catenin: A key mediator of Wnt signaling
73. Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila
74. Pattern formation in the Drosophila retina
75. Heart development in Drosophila requires the segment polarity gene wingless
76. Analysis of genetic mosaics in developing and adult Drosophila tissues
77. Biochemical characterization of the Drosophila axin protein
78. The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
79. Direct and long-range action of a wingless morphogen gradient