Xwnt11 is a target of Xenopus Brachyury: Regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway

Development

Volumn 127, Issue 10, 2000, Pages 2227-2238

  Tada, Masazumi ^a   Smith, J C ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Brachyury; Dishevelled; Gastrulation; Target gene; Wnt; Xenopus

Indexed keywords

BETA CATENIN;

ARTICLE; EMBRYO DEVELOPMENT; GASTRULA; GASTRULATION; GENE EXPRESSION; MESODERM; MORPHOGENESIS; NONHUMAN; NOTOCHORD; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; XENOPUS;

ACTIVINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CHROMOSOME MAPPING; GASTRULA; GLYCOPROTEINS; INHIBINS; MORPHOGENESIS; PHOSPHOPROTEINS; SIGNAL TRANSDUCTION; T-BOX DOMAIN PROTEINS; WNT PROTEINS; XENOPUS; XENOPUS PROTEINS;

AMPHIBIA; REPTILIA; VERTEBRATA; XENOPUS BRACHYURY;

EID: 0034130385     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (79)

1. Adler, P. N. (1992). The genetic control of tissue polarity in Drosophila. BioEssays 14, 735-741.
2. Amores, A., Force, A., Yan, Y. L., Joly, L., Amemiya, C., Fritz, A., Ho, R. K., Langeland, J., Prince, V., Wang, Y. L. et al. (1998). Zebralish hox clusters and vertebrate genome evolution. Science 282, 1711-1714.
3. Axelrod, J. D., Miller, J. R., Shulman, J. M., Moon, R. T. and Perrimon, N. (1998). Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev. 12, 2610-2622.
4. Barrett, K., Leptin, M. and Settleman, J. (1997). The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation. Cell 91, 905-915.
5. Blumberg, B., Wright, C. V. E., De Robertis, E. M. and Cho, K. W. Y. (1991). Organizer-specific homeobox genes in Xenopus laevis embryos. Science 253, 194-196.
6. Boutros, M. and Mlodzik, M. (1999). Dishevelled: at the crossroads of divergent intracellular signaling pathways. Mech. Dev. 83, 27-37.
7. Boutros, M., Paricio, N., Strutt, D. I. and Mlodzik, M. (1998). Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling. Cell 94, 109-118.
8. Brannon, M., Gomperts, M., Sumoy, L., Moon, R. T. and Kimelman, D. (1997). A β-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus. Genes Dev. 11, 2359-2370.
9. Brieher, W. M. and Gumbiner, B. M. (1994). Regulation of C-cadherin function during activin induced morphogenesis of Xenopus animal caps. J. Cell Biol. 126, 519-527.
10. Cadigan, K. M. and Nusse, R. (1997). Wnt signaling: a common theme in animal development. Genes Dev. 11, 3286-3305.
11. Casey, E. S., Tada, M., Fairclough, L., Wylie, C. C., Heasman, J. and Smith, J. C. (1999). Bix4 is activated by VegT and mediates endoderm formation in Xenopus development. Development 126, 4193-4200.
12. Christian, J. L., McMahon, J. A., McMahon, A. P. and Moon, R. T. (1991). Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm-inducing factors, may play a role in ventral mesodermal patterning during embryogenesis. Development 111, 1045-1055.
13. Conlon, F. L., Sedgwick, S. G., Weston, K. M. and Smith, J. C. (1996). Inhibition of Xbra transcription activation causes detects in mesodermalpatterning and reveals autoregulation of Xbra in dorsal mesoderm. Development 122, 2427-2435.
14. Conlon, F. L. and Smith, J. C. (1999). Interference with Brachyury function inhibits convergent extension, causes apoptosis, and reveals separate requirements in the FGF and activin signalling pathways. Dev. Biol. 213, 85-100.
15. Cooke, J., Smith, J. C., Smith, E. J. and Yaqoob, M. (1987). The organization of mesodermal pattern in Xenopus laevis: experiments using a Xenopus mesoderm-inducing factor. Development 101, 893-908.
16. Cunliffe, V. and Smith, J. C. (1992). Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue. Nature 358, 427-430.
17. Cunliffe, V. and Smith, J. C. (1994). Specification of mesodermal pattern in Xenopus laevis by interactions between Brachyury, noggin and Xwnt-8. EMBO J. 13, 349-359.
18. Deardorff, M. A., Tan, C., Conrad, L. J. and Klein, P. S. (1998). Frizzled-8 is expressed in the Spemann organizer and plays a role in early morphogenesis. Development 125, 2687-2700.
19. Du, J. S., Purcell, S. M., Christian, J. L., McGrew, L. L. and Moon, R. T. (1995). Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos. Mol. Cell. Biol. 15, 2625-2634.
20. Fagotto, F., Guger, K. and Gumbiner, B. M. (1997). Induction of the primary dorsalizing center in Xenopus by the Wnt/GSK/beta-catenin signaling pathway, but not by Vg1, Activin or Noggin. Development 124, 453-460.
21. Gawantka, V., Delius, H., Hirschfeld, K., Blumenstock, C. and Niehrs, C. (1995). Antagonizing the Spemann organizer: role of the homeobox gene Xvent-1. EMBO J. 14, 6268-6279.
22. Glinka, A., Delius, H., Blumenstock, C. and Niehrs, C. (1996). Combinatorial signalling by Xwnt11 and Xnr3 in the organizer epithelium. Mech. Dev. 60, 221-231.
23. Griffin, K. J., Amacher, S. L., Kimmel, C. B. and Kimelman, D. (1998). Molecular identification of spadetail: regulation of zebrafish trunk and tail mesoderm formation by T-box genes. Development 125, 3379-3388.
24. Harland, R. M. (1991). In situ hybridization: an improved whole mount method for Xenopus embryos. Meth. Cell Biol. 36, 675-685.
25. Heisenberg, C.-P., Tada, M., Rauch, G.-J, Saúde, L., Concha, M. L., Geisler, R., Stemple, D. L., Smith, J. C. and Wilson, S. W. (2000). Silberblick/Wnt11 activity mediates convergent extension during zebrafish gastrulation. Nature, in press.
26. Herrmann, B. G., Labeit, S., Poutska, A., King, T. R. and Lehrach, H. (1990). Cloning of the T gene required in mesoderm formation in the mouse. Nature 343, 617-622.
27. Hoppler, S., Brown, J. D. and Moon, R. T. (1996). Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos. Genes Dev. 10, 2805-2817.
28. Hopwood, N. D., Pluck, A. and Gurdon, J. B. (1989). MyoD expression in the forming somites is an early response to mesoderm induction in Xenopus embryos. Embo J 8, 3409-3417.
29. Hopwood, N. D., Pluck, A. and Gurdon, J. B. (1991). Xenopus Myf-5 marks early muscle cells and can activate muscle genes ectopically in early embryos. Development 111, 551-560.
30. Horb, M. E. and Thomsen, G. H. (1997). A vegetally-localized T-box transcription factor in Xenopus eggs specifies mesoderm and endoderm and is essential for embryonic mesoderm formation. Development 124, 1689-1698.
31. Isaacs, H. V., Pownall, M. E. and Slack, J. M. W. (1994). eFGF regulates Xbra expression during Xenopus gastrulation. EMBO J. 13, 4469-4481.
32. Isaacs, H. V., Tannahill, D. and Slack, J. M. W. (1992). Expression of a novel FGF in the Xenopus embryo. A new candidate inducing factor for mesoderm formation and anteraposterior specification. Development 114, 711-720.
33. Itoh, K. and Sokol, S. Y. (1997). Graded amounts of Xenopus dishevelled specify discrete anteroposterior cell fates in prospective ectoderm. Mech. Dev. 61, 113-125.
34. Keller, R. B., Shih, J. and Domingo, C. (1992). The patterning and functioning of protrusive activity during convergence and extension of the Xenopus organiser. Development (suppl.). 81-91.
35. Keller, R. E. (1986). The cellular basis of amphibian gastrulation. Dev Biol N Y 2, 241-327.
36. Kim, S.-H., Yamamoto, A., Bouwmeester, T., Agius, E. and De Robertis, E. M. (1998). The role of paraxial protocadherin in selective adhesion and cell movements of the mesoderm during Xenopus gastrulation. Development 125, 4681-4691.
37. Kintner, C. R. and Brockes, J. P. (1984). Monoclonal antibodies recognise blastemal cells derived from differentiating muscle in newt limb regeneration. Nature 308, 67-69.
38. Kishida, S., Yamamoto, H., Hino, S., Ikeda, S., Kishida, M. and Kikuchi, A. (1999). DIX domains of Dv1 and axin are necessary for protein interactions and their ability to regulate beta-catenin stability. Mol. Cell. Biol. 19, 4414-4422.
39. Kispert, A., Korschorz, B. and Herrmann, B. G. (1995). The T protein encoded by Brachyury is a tissue-specific transcription factor. EMBO J. 14, 4763-4772.
40. Krasnow, R. E. and Adler, P. N. (1994). A single frizzled protein has a dual function in tissue polarity. Development 120, 1883-1893.
41. Ku, M. and Melton, D. A. (1993). Xwnt-11, a maternally expressed Xenopus wnt gene. Development 119, 1161-1173.
42. Lemaire, P., Garrett, N. and Gurdon, J. B. (1995). Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal vegetal cells of blastulae and able to induce a complete secondary axis. Cell 81, 85-94.
43. Li, L., Yuan, H., Xie, W., Mao, J., Caruso, A. M., Sussman, D. J. and Wu, D. (1999). Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells. J. Biol. Chem. 274, 129-134.
44. Lustig, K. D., Kroll, K. L., Sun, E. E. and Kirschner, M. W. (1996). Expression cloning of a Xenopus T-related gene (Xombi) involved in mesodermal patterning and blastopore lip formation. Development 122, 4001-4012.
45. Makita, R., Mizuno, T., Koshida, S., Kuroiwa, A. and Takeda, H. (1998). Zebrafish wnt11: pattern and regulation of the expression by the yolk cell and No tail activity. Mech. Del. 71, 165-176.
46. Mohun, T. J., Brennan, S., Dathan, N., Fairman, S. and Gurdon, J. B. (1984). Cell type-specific activation of actin genes in the early amphibian embryo. Nature 311, 716-721.
47. Molenaar, M., van de Wetering, M., Oosterwegel, M., Peter-Maduro, J., Godsave, S., Korinek, V., Roose, J., Destree, O. and Clevers, H. (1996). XTcf-3 transcription factor mediates β-catenin-induced axis formation in Xenopus embryos. Cell 86, 391-399.
48. Moon, R. T., Campbell, R. M., Christian, J. L., McGrew, L. L., Shih, J. and Fraser, S. (1993). Xwnt-5A: a maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis. Development 119, 97-111.
49. Morgan, R., Hooiveld, M. H. W., In der Rieden, P. and Durston, A. J. (1999). A conserved 30 base pair element in the Wnt-5a promoter is sufficient both to drive its early embryonic expression and to mediate its repression by otx2. Mech. Dev. 85, 97-102.
50. Nieuwkoop, P. D. (1969). The formation of mesoderm in Urodelean amphibians. I. Induction by the endoderm. Wilhelm Roux's Arch. EntwMech. Org. 162, 341-373.
51. Nieuwkoop, P. D. and Faber, J. (1975). Normal Table of Xenopus laevis (Daudin). Amsterdam: North Holland.
52. O'Reilly, M.-A. J., Smith, J. C. and Cunliffe, V. (1995). Patterning of the mesoderm in Xenopus: dose-dependent and synergistic effects of Brachyury and Pintallavis. Development 121, 1351-1359.
53. Ponting, C. P. and Bork, P. (1996). Pleckstrin's repeat performance: a novel domain in G-protein signaling? Trends Biochem. Sci. 21, 245-246.
54. Ponting, C. P., Phillips, C., Davies, K. E. and Blake, D. J. (1997). PDZ domains: targeting signalling molecules to sub-membranous sites. BioEssays 19, 469-479.
55. Saka, Y., Tada, M. and Smith, J. C. (2000). A screen for targets of the Xenopus T-box gene Xbra. Mech. Dev. (in press).
56. Sambrook, J., Fritsch, E. F. and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual. New York: Cold Spring Harbor Press.
57. Sasai, Y., Lu, B., Steinbeisser, H., Geisssert, D., Gont, L. K. and De Robertis, E. M. (1994). Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79, 779-790.
58. Schulte-Merker, S. and Smith, J. C. (1995). Mesoderm formation in response to Brachyury requires FGF signalling. Curr. Biol. 5, 62-67.
59. Schulte-Merker, S., van Eeden, F. M., Halpern, M. E., Kimmel, C. B. and Nüsslein-Volhard, C. (1994). No tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene. Development 120, 1009-1015.
60. Sheldahl, L. C., Park, M., Malbon, C. C. and Moon, R. T. (1999). Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner. Curr. Biol. 9, 695-698.
61. Shin, J. and Keller, R. (1992). Cell motility driving mediolateral intercalation in explants of Xenopus laevis. Development 116, 901-914.
62. Slusarski, D. C., Corces, V. G. and Moon, R. T. (1997). Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling. Nature 390, 410-413.
63. Smith, J. C. (1993). Purifying and assaying mesoderm-inducing factors from vertebrate embryos. In Cellular Interactions in Development - a Practical Approach, (ed. Hartley, D.), pp. 181-204. Oxford: Oxford University Press.
64. Smith, J. C., Price, B. M. J., Green, J. B. A., Weigel, D. and Herrmann, B. G. (1991). Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 67, 79-87.
65. Smith, J. C., Symes, K., Hynes, R. O. and DeSimone, D. (1990). Mesoderm induction and the control of gastrulation in Xenopus laevis: the roles of libronectin and integrins. Development 108, 289-298.
66. Smith, J. C. and Watt, F. M. (1985). Biochemical specificity of Xenopus notochord. Differentiation 29, 109-115.
67. Sokol, S. Y. (1996). Analysis of Dishevelled signalling pathways during Xenopus development. Curr. Biol. 6, 1456-1467.
68. Sokol, S. Y., Klingensmith, J., Perrimon, N. and Itoh, K. (1995). Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled. Development 121, 1637-1647.
69. Stennard, F., Carnac, G. and Gurdon, J. B. (1996). The Xenopus T-box gene, Antipodean, encodes a vegetally localised maternal mRNA and can trigger mesoderm formation. Development 122, 4179-4188.
70. Strutt, D. I., Weber, U. and Mlodzik, M. (1997). The role of RhoA in tissue polarity and Frizzled signalling. Nature 387, 292-295.
71. Symes, K. and Smith, J. C. (1987). Gastrulation movements provide an early marker of mesoderm induction in Xenopus. Development 101, 339-349.
72. Tada, M., Casey, E., Fairclough, L. and Smith, J. C. (1998). Bixl. a direct target of Xenopus T-box genes, causes formation of ventral mesoderm and endoderm. Development 125, 3997-4006.
73. Tada, M., O'Reilly, M.-A. J. and Smith, J. C. (1997). Analysis of competence and of Brachyury autoinduction by use of hormone-inducible Xbra. Development 124, 2225-2234.
74. Torres, M. A., Yang-Snyder, J. A., Purcell, S. M., DeMarais, A. A., McGrew, L. L. and Moon, R. T. (1996). Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development. J. Cell Biol. 133, 1123-1137.
75. Wilson, P. and Keller, R. (1991). Cell rearrangement during gastrulation of Xenopus: direct observation of cultured explants. Development 112, 289-300.
76. Wilson, V., Manson, L., Skarnes, W. C. and Beddington, R. S. P. (1995). The T gene is necessary for normal mesodermal morphogenetic cell movements during gastrulation. Development 121, 877-886.
77. Yanagawa, S., van Leeuvven, F., Wodarz, A., Klingensmith, J. and Nusse, R. (1995). The Dishevelled protein is modified by Wingless signaling in Drosophila. Genes Dev. 9, 1087-1097.
78. Zhang, J. and King, M. L. (1996). Xenopus VegT RNA is localized to the vegetal cortex during oogenesis and encodes a novel T-box transcription factor involved in mesodermal patterning. Development 122, 4119-4129.
79. Zhong, Y., Brieher, W. M. and Gumbiner, B. M. (1999). Analysis of C-cadherin regulation during tissue morphogenesis with an activating antibody. J. Cell Biol. 144, 351-359.