-
1
-
-
0030978351
-
β-catenin is a target for the ubiquitin-proteasome pathway
-
Aberle, H., Bauer, A., Stappert, J., Kispert, A. and Kemler, R. (1997) β-Catenin is a target for the ubiquitin-proteasome pathway. EMBO J., 16, 3797-3804.
-
(1997)
EMBO J.
, vol.16
, pp. 3797-3804
-
-
Aberle, H.1
Bauer, A.2
Stappert, J.3
Kispert, A.4
Kemler, R.5
-
2
-
-
0032562603
-
Functional interaction of an Axin homolog, conductin, with β-catenin, APC and GSK3β
-
Behrens, J., Jerchow, B., Wurtele, M., Grimm, J., Asbrand, C., Wirtz, R., Kuhl, M., Wedlich, D. and Birchmeier, W. (1998) Functional interaction of an Axin homolog, conductin, with β-catenin, APC and GSK3β. Science, 280, 596-598.
-
(1998)
Science
, vol.280
, pp. 596-598
-
-
Behrens, J.1
Jerchow, B.2
Wurtele, M.3
Grimm, J.4
Asbrand, C.5
Wirtz, R.6
Kuhl, M.7
Wedlich, D.8
Birchmeier, W.9
-
3
-
-
0032504052
-
Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling
-
Boutros, M., Paricio, N., Strutt, D. and Mlodzik, M. (1998) Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling. Cell, 94, 109-118.
-
(1998)
Cell
, vol.94
, pp. 109-118
-
-
Boutros, M.1
Paricio, N.2
Strutt, D.3
Mlodzik, M.4
-
4
-
-
0030930442
-
A β-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus
-
Brannon, M., Gomperts, M., Sumoy, L., Moon, R.T. and Kimelman, D. (1997) A β-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus. Genes Dev., 11, 2359-2370.
-
(1997)
Genes Dev.
, vol.11
, pp. 2359-2370
-
-
Brannon, M.1
Gomperts, M.2
Sumoy, L.3
Moon, R.T.4
Kimelman, D.5
-
5
-
-
0031456158
-
Wnt signaling: A common theme in animal development
-
Cadigan, K.M. and Nusse, R. (1997) Wnt signaling: a common theme in animal development. Genes Dev., 11, 3286-3305.
-
(1997)
Genes Dev.
, vol.11
, pp. 3286-3305
-
-
Cadigan, K.M.1
Nusse, R.2
-
6
-
-
0029811434
-
Wingless inactivates glycogen synthase kinase 3 via an intracellular signaling pathway which involves a protein kinase C
-
Cook, D., Fry, M.J., Hughes, K., Woodgetts, J.R. and Dale, T. (1996) Wingless inactivates glycogen synthase kinase 3 via an intracellular signaling pathway which involves a protein kinase C. EMBO J., 15, 4526-4536.
-
(1996)
EMBO J.
, vol.15
, pp. 4526-4536
-
-
Cook, D.1
Fry, M.J.2
Hughes, K.3
Woodgetts, J.R.4
Dale, T.5
-
7
-
-
0032518695
-
Signal transduction by the Wnt family of ligands
-
Dale, T.C. (1998) Signal transduction by the Wnt family of ligands. Biochem. J., 329, 209-223.
-
(1998)
Biochem. J.
, vol.329
, pp. 209-223
-
-
Dale, T.C.1
-
8
-
-
0026903966
-
The role of Wnt genes in vertebrate development
-
Dickinson, M.E. and McMahon, A.P. (1992) The role of Wnt genes in vertebrate development. Curr. Opin. Genet. Dev., 2, 562-566.
-
(1992)
Curr. Opin. Genet. Dev.
, vol.2
, pp. 562-566
-
-
Dickinson, M.E.1
McMahon, A.P.2
-
9
-
-
0030604722
-
Crystal structures of a complexed and peptide-free membrane protein-binding domain: Molecular basis of peptide recognition by PDZ
-
Doyle, D.A., Lee, A., Lewis, J., Kim, E., Sheng, M. and MacKinnon, R. (1996) Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell, 85, 1067-1076.
-
(1996)
Cell
, vol.85
, pp. 1067-1076
-
-
Doyle, D.A.1
Lee, A.2
Lewis, J.3
Kim, E.4
Sheng, M.5
Mackinnon, R.6
-
10
-
-
0030739838
-
Carcinogenesis: A balance between beta-catenin and APC
-
Gumbiner, B.M. (1997) Carcinogenesis: a balance between beta-catenin and APC. Curr. Biol., 7, R443-R446.
-
(1997)
Curr. Biol.
, vol.7
-
-
Gumbiner, B.M.1
-
11
-
-
0031666549
-
Propagation and localization of Wnt signaling
-
Gumbiner, B.M. (1998) Propagation and localization of Wnt signaling. Curr. Opin. Genet. Dev., 8, 430-435.
-
(1998)
Curr. Opin. Genet. Dev.
, vol.8
, pp. 430-435
-
-
Gumbiner, B.M.1
-
12
-
-
0033548495
-
Negative regulation of wingless signaling by D-Axin, a Drosophila homolog of Axin
-
Hamada, F. et al. (1999) Negative regulation of Wingless signaling by D-Axin, a Drosophila homolog of Axin. Science, 283, 1739-1742.
-
(1999)
Science
, vol.283
, pp. 1739-1742
-
-
Hamada, F.1
-
13
-
-
0031856533
-
Modulation of transcriptional regulation by Lef-1 in response to Wnt-1 signaling and association with β-catenin
-
Hsu, S.C., Galceran, J. and Grosschedl, R. (1998) Modulation of transcriptional regulation by Lef-1 in response to Wnt-1 signaling and association with β-catenin. Mol. Cell. Biol., 18, 4807-4818.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 4807-4818
-
-
Hsu, S.C.1
Galceran, J.2
Grosschedl, R.3
-
14
-
-
0345343608
-
Nuclear localization of β-catenin by interaction with transcription factor LEF-1
-
Huber, O., Korn, R., McLaughlin, J., Ohsugi, M., Herrmann, B.G. and Kemler, R. (1996) Nuclear localization of β-catenin by interaction with transcription factor LEF-1. Mech. Dev., 59, 3-10.
-
(1996)
Mech. Dev.
, vol.59
, pp. 3-10
-
-
Huber, O.1
Korn, R.2
McLaughlin, J.3
Ohsugi, M.4
Herrmann, B.G.5
Kemler, R.6
-
15
-
-
0032473355
-
Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3-β and β-catenin and promotes GSK-3-β-dependent phosphorylation of β-catenin
-
Ikeda, S., Kishida, S., Yamamoto, H., Murai, H., Koyama, S. and Kikuchi, A. (1998) Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3-β and β-catenin and promotes GSK-3-β-dependent phosphorylation of β-catenin. EMBO J., 17, 1371-1384.
-
(1998)
EMBO J.
, vol.17
, pp. 1371-1384
-
-
Ikeda, S.1
Kishida, S.2
Yamamoto, H.3
Murai, H.4
Koyama, S.5
Kikuchi, A.6
-
16
-
-
0031024689
-
Activation of a novel proto-oncogene, Fratl, contributes to progression of mouse T-cell lymphomas
-
Jonkers, J., Korswagen, H.C., Acton, D., Breuer, M. and Berns, A. (1997) Activation of a novel proto-oncogene, Fratl, contributes to progression of mouse T-cell lymphomas. EMBO J., 16, 441-450.
-
(1997)
EMBO J.
, vol.16
, pp. 441-450
-
-
Jonkers, J.1
Korswagen, H.C.2
Acton, D.3
Breuer, M.4
Berns, A.5
-
17
-
-
0032079884
-
Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of β-catenin
-
Kishida, S., Yamamoto, H., Ikeda, S., Kishida, M., Sakamoto, I., Koyama, S. and Kikuchi, A. (1998) Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of β-catenin. J. Biol. Chem., 273, 10823-10826.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10823-10826
-
-
Kishida, S.1
Yamamoto, H.2
Ikeda, S.3
Kishida, M.4
Sakamoto, I.5
Koyama, S.6
Kikuchi, A.7
-
18
-
-
0028568147
-
Signaling by wingless in Drosophila
-
Klingensmith, J. and Nusse, R. (1994) Signaling by wingless in Drosophila. Dev. Biol., 166, 396-414.
-
(1994)
Dev. Biol.
, vol.166
, pp. 396-414
-
-
Klingensmith, J.1
Nusse, R.2
-
19
-
-
0030219387
-
Conservation of dishevelled structure and function between flies and mice: Isolation and characterization of Dvl2
-
Klingensmith, J., Yang, Y., Axelrod, J.D., Beier, D.R., Perrimon, N. and Sussman, D.J. (1996) Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2. Mech. Dev., 58, 15-26.
-
(1996)
Mech. Dev.
, vol.58
, pp. 15-26
-
-
Klingensmith, J.1
Yang, Y.2
Axelrod, J.D.3
Beier, D.R.4
Perrimon, N.5
Sussman, D.J.6
-
20
-
-
0030975671
-
Constitutive transcriptional activation by a β-catenin-Tcf complex in APC-/-colon carcinoma
-
Korinek, V., Barker, N., Morin, P.J., van Wichen, D., de Weger, R., Kinzler, K.W., Vogelstein, B. and Clevers, H. (1997) Constitutive transcriptional activation by a β-catenin-Tcf complex in APC-/-colon carcinoma. Science, 275, 1784-1787.
-
(1997)
Science
, vol.275
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
Van Wichen, D.4
De Weger, R.5
Kinzler, K.W.6
Vogelstein, B.7
Clevers, H.8
-
21
-
-
0032898364
-
Dishevelled proteins lead to two different signaling pathways; regulation of the JNK and β-catenin pathways
-
Li, L., Yuan, H., Xie, W., Mao, J., McMahon, E., Sussman, D. and Wu, D. (1999) Dishevelled proteins lead to two different signaling pathways; regulation of the JNK and P-catenin pathways. J. Biol. Chem., 274, 129-134.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 129-134
-
-
Li, L.1
Yuan, H.2
Xie, W.3
Mao, J.4
McMahon, E.5
Sussman, D.6
Wu, D.7
-
22
-
-
0001003110
-
XTcf-3 transcription factor mediates β-catenin-induced axis formation in Xenopus embryos
-
Molenaar, M., van de Watering, M., Oosterwegel, M., Peterson-Maduro, J., Godsave, S., Korinek, V., Roose, J., Destree, O. and Clevers, H. (1996) XTcf-3 transcription factor mediates β-catenin-induced axis formation in Xenopus embryos. Cell, 86, 391-399.
-
(1996)
Cell
, vol.86
, pp. 391-399
-
-
Molenaar, M.1
Van De Watering, M.2
Oosterwegel, M.3
Peterson-Maduro, J.4
Godsave, S.5
Korinek, V.6
Roose, J.7
Destree, O.8
Clevers, H.9
-
23
-
-
0002637679
-
Microinjection and expression of synthetic mRNAs in Xenopus embryos
-
Moon, R.T. and Christian, J.L. (1989) Microinjection and expression of synthetic mRNAs in Xenopus embryos. Technique, 1, 76-89.
-
(1989)
Technique
, vol.1
, pp. 76-89
-
-
Moon, R.T.1
Christian, J.L.2
-
24
-
-
0030949463
-
Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC
-
Morin, P.J., Sparks, A.B., Korinek, V., Barker, N., Clevers, H., Vogelstein, B. and Kinzler, K.W. (1997) Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC. Science, 275, 1787-1790.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
Barker, N.4
Clevers, H.5
Vogelstein, B.6
Kinzler, K.W.7
-
25
-
-
0020407569
-
A major developmental transition in early Xenopus embryos. I. Characterization and timing of cellular changes at the midblastula stage
-
Newport, J. and Kirschner, M.W. (1982) A major developmental transition in early Xenopus embryos. I. Characterization and timing of cellular changes at the midblastula stage. Cell, 30, 675-686.
-
(1982)
Cell
, vol.30
, pp. 675-686
-
-
Newport, J.1
Kirschner, M.W.2
-
26
-
-
0026772731
-
Wnt genes
-
Nusse, R. and Varmus, H.E. (1992) Wnt genes. Cell, 69, 1073-1087.
-
(1992)
Cell
, vol.69
, pp. 1073-1087
-
-
Nusse, R.1
Varmus, H.E.2
-
27
-
-
0028209401
-
The genetic basis of patterned boldness in Drosophila
-
Perrimon, N. (1994) The genetic basis of patterned boldness in Drosophila. Cell, 76, 781-784.
-
(1994)
Cell
, vol.76
, pp. 781-784
-
-
Perrimon, N.1
-
28
-
-
0031557898
-
The adenomatous polyposis coli (APC) tumor suppressor
-
Polakis, P. (1997) The adenomatous polyposis coli (APC) tumor suppressor. Biochim. Biophys. Acta, 1332, F127-147.
-
(1997)
Biochim. Biophys. Acta
, vol.1332
-
-
Polakis, P.1
-
29
-
-
0030200001
-
Pleckstrin's repeat performance: A novel domain in G-protein signaling?
-
Ponting, C.P. and Bork, P. (1996) Pleckstrin's repeat performance: a novel domain in G-protein signaling? Trends Biochem. Sci., 21, 245-246.
-
(1996)
Trends Biochem. Sci.
, vol.21
, pp. 245-246
-
-
Ponting, C.P.1
Bork, P.2
-
30
-
-
0031171361
-
PDZ domains: Targeting signaling molecules to sub-membranous sites
-
Ponting, C.P., Phillips, C., Davies, K.E. and Blake, D.J. (1997) PDZ domains: targeting signaling molecules to sub-membranous sites. BioEssays, 19, 469-479.
-
(1997)
BioEssays
, vol.19
, pp. 469-479
-
-
Ponting, C.P.1
Phillips, C.2
Davies, K.E.3
Blake, D.J.4
-
31
-
-
0029664368
-
Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly
-
Rubinfeld, B., Albert, I., Porfiri, E., Fiol, C., Munemitsu, S. and Polakis, P. (1996) Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly. Science, 272, 1023-1026.
-
(1996)
Science
, vol.272
, pp. 1023-1026
-
-
Rubinfeld, B.1
Albert, I.2
Porfiri, E.3
Fiol, C.4
Munemitsu, S.5
Polakis, P.6
-
32
-
-
0027738023
-
Association of the APC gene product with β-catenin
-
Rubinfeld, B., Souza, B., Albert, I., Muller, O., Chamberlain, S.H., Masiarz, F.R., Munemitsu, S. and Polakis, P (1993) Association of the APC gene product with β-catenin. Science, 262, 1731-1734.
-
(1993)
Science
, vol.262
, pp. 1731-1734
-
-
Rubinfeld, B.1
Souza, B.2
Albert, I.3
Muller, O.4
Chamberlain, S.H.5
Masiarz, F.R.6
Munemitsu, S.7
Polakis, P.8
-
33
-
-
0032539945
-
Bridging of β-catenin and glycogen synthase kinase-3-β by Axin and inhibition of β-catenin-mediated transcription
-
Sakanaka, C., Weiss, J.B. and Williams, L.T. (1998) Bridging of β-catenin and glycogen synthase kinase-3-β by Axin and inhibition of β-catenin-mediated transcription. Proc. Natl Acad. Sci. USA, 95, 3020-3023.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 3020-3023
-
-
Sakanaka, C.1
Weiss, J.B.2
Williams, L.T.3
-
34
-
-
0030917227
-
The role of RhoA in tissue polarity and frizzled signaling
-
Strutt, D., Weber, U. and Mlodzik, M. (1997) The role of RhoA in tissue polarity and frizzled signaling. Nature, 387, 292-295.
-
(1997)
Nature
, vol.387
, pp. 292-295
-
-
Strutt, D.1
Weber, U.2
Mlodzik, M.3
-
35
-
-
0027944513
-
Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled
-
Sussman, D.J., Klingensmith, J., Salinas, P., Adams, P.S., Nusse, R. and Perrimon, N. (1994) Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled. Dev. Biol., 166, 73-86.
-
(1994)
Dev. Biol.
, vol.166
, pp. 73-86
-
-
Sussman, D.J.1
Klingensmith, J.2
Salinas, P.3
Adams, P.S.4
Nusse, R.5
Perrimon, N.6
-
36
-
-
0029914169
-
Isolation and characterization of mouse dishevelled-3
-
Tsang, M., Lijam, N., Yang, Y., Beier, D.R., Wynshaw-Boris, A. and Sussman, D.J. (1996) Isolation and characterization of mouse dishevelled-3. Dev. Dyn., 207, 253-262.
-
(1996)
Dev. Dyn.
, vol.207
, pp. 253-262
-
-
Tsang, M.1
Lijam, N.2
Yang, Y.3
Beier, D.R.4
Wynshaw-Boris, A.5
Sussman, D.J.6
-
37
-
-
0028306459
-
Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate
-
Tumer, D.L. and Weintraub, H. (1994) Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Gene Dev., 8, 1434-1447.
-
(1994)
Gene Dev.
, vol.8
, pp. 1434-1447
-
-
Tumer, D.L.1
Weintraub, H.2
-
38
-
-
0033068154
-
The SCF β-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IκBα and β-catenin and stimulates IκBα ubiquitination in vitro
-
Winston, J.T., Strack, P., Beer-Romero, P., Chu, C.Y., Elledge, S.J. and Harper, J.W. (1999) The SCF β-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IκBα and β-catenin and stimulates IκBα ubiquitination in vitro. Genes Dev., 13, 270-283.
-
(1999)
Genes Dev.
, vol.13
, pp. 270-283
-
-
Winston, J.T.1
Strack, P.2
Beer-Romero, P.3
Chu, C.Y.4
Elledge, S.J.5
Harper, J.W.6
-
39
-
-
0031943002
-
Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3β and β-catenin and inhibits axis formation of Xenopus embryos
-
Yamamoto, H., Kishida, S., Uochi, T., Ikeda, S., Koyama, S., Asashima, M. and Kikuchi, A. (1998) Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3β and β-catenin and inhibits axis formation of Xenopus embryos. Mol. Cell. Biol., 18, 2867-2875.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2867-2875
-
-
Yamamoto, H.1
Kishida, S.2
Uochi, T.3
Ikeda, S.4
Koyama, S.5
Asashima, M.6
Kikuchi, A.7
-
40
-
-
0028989112
-
The dishevelled protein is modified by wingless signaling in Drosophila
-
Yanagawa, S., van Leeuwen, F., Wodarz, A., Klingensmith, J. and Nusse, R. (1995) The dishevelled protein is modified by wingless signaling in Drosophila. Genes Dev., 9, 1087-1097.
-
(1995)
Genes Dev.
, vol.9
, pp. 1087-1097
-
-
Yanagawa, S.1
Van Leeuwen, F.2
Wodarz, A.3
Klingensmith, J.4
Nusse, R.5
-
41
-
-
0029683606
-
The axis-inducing activity, stability and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
-
Yost, C., Torres, M., Miller, J.R., Huang, E., Kimelman, D. and Moon, R.T. (1996) The axis-inducing activity, stability and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes Dev., 10, 1443-1454.
-
(1996)
Genes Dev.
, vol.10
, pp. 1443-1454
-
-
Yost, C.1
Torres, M.2
Miller, J.R.3
Huang, E.4
Kimelman, D.5
Moon, R.T.6
-
42
-
-
0032511194
-
GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis
-
Yost, C., Farr, G.H., Pierce, S.B., Ferkey, D.M., Chen, M.M. and Kimelman, D. (1998) GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis. Cell, 93, 1031-1041.
-
(1998)
Cell
, vol.93
, pp. 1031-1041
-
-
Yost, C.1
Farr, G.H.2
Pierce, S.B.3
Ferkey, D.M.4
Chen, M.M.5
Kimelman, D.6
-
43
-
-
0031457978
-
The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation
-
Zeng, L. et al. (1997) The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell, 90, 181-192.
-
(1997)
Cell
, vol.90
, pp. 181-192
-
-
Zeng, L.1
|