A new low density lipoprotein receptor related protein, LRP5, is expressed in hepatocytes and adrenal cortex, and recognizes apolipoprotein E

Journal of Biochemistry

Volumn 124, Issue 6, 1998, Pages 1072-1076

  Kim, Dong Ho ^a   Inagaki, Yousuke ^a   Suzuki, Takashi ^b   Ioka, Ryoichi X ^a   Yoshioka, Shiroh Z ^a   Magoori, Kenta ^a   Kang, Man Jong ^b   Cho, Yuko ^a   Nakano, Akira Z ^a   Liu, Qiong ^a   Fujino, Takahiro ^a   Suzuki, Hiroyuki ^a   Sasano, Hironobu ^b   Yamamoto, Tokuo T ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

apoE; LDL receptor family; LDL receptor related protein; Lipoprotein

Indexed keywords

APOLIPOPROTEIN E; COMPLEMENTARY DNA; LOW DENSITY LIPOPROTEIN RECEPTOR; MEMBRANE PROTEIN; MESSENGER RNA;

ADENOVIRUS; ADRENAL CORTEX; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; FOAM CELL; GENE ISOLATION; GENETIC TRANSDUCTION; HUMAN; HYPERLIPIDEMIA; IN SITU HYBRIDIZATION; LIVER CELL; MALE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RABBIT; RECEPTOR BINDING;

ADENOVIRIDAE; ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0032446373     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022223     Document Type: Article

References (10)

1. Yamamoto, T. and Bujo, H. (1996) Close encounters with apolipoprotein E receptors. Curr. Opin. Lipidol. 7, 298-302
2. Yamamoto, T., Davis, C.G., Brown, M.S., Schneider, W.J., Casey, M.L., Goldstein, J.L., and Russell, D.W. (1984) The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA. Cell 39, 27-38
3. Ishii, H., Kim, D.H., Fujita, T., Endo, Y., Saeki, S., and Yamamoto, T.T. (1998) cDNA cloning of a new low density lipoprotein receptor-related protein and mapping of its gene (LRP3) to chromosome bands 19q12-13.2. Genomics 51, 132-135
4. Tomita, Y., Kim, D.H., Magoori, K., Fujino, T., and Yamamoto, T.T. (1998) A novel low density lipoprotein receptor related protein with type II membrane protein like structure is abundant in heart. J. Biochem. 124, 784-789
5. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
6. Sasano, H., Uzuki, M., Sawai, T., Nagura, H., Matsunaga, G., Kashimoto, O., and Harada, N. (1997) Aromatase in human bone tissue. J. Bone Miner. Res. 12, 1416-1423
7. Miyake, S., Makimura, M., Kanegae, Y., Harada, S., Sato, Y., Takamori, K., Tokuda, C., and Saito, I. (1996) Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc. Natl. Acad. Sci. USA 93, 1320-1324
8. Kim, D.H., Iijima, H., Goto, K., Sakai, J., Ishii, H., Kim, H.J., Suzuki, H., Kondo, H., Saeki, S., and Yamamoto, T. (1996) Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain. J. Biol. Chem. 271, 8373-8380
9. Takahashi, S., Kawarabayasi, Y., Nakai, T., Sakai, J., and Yamamoto, T. (1992) Rabbit very low density lipoprotein receptor: a low density lipoprotein receptor-like protein with distinct ligand specificity. Proc. Natl. Acad. Sci. USA 89, 9252-9256
10. Hey, P.J., Twells, R.C.J., Phillips, M.S., Nakagawa, Y., Brown, S.D., Kawaguchi, Y., Cox, R., Xie, G., Dugan, V., Hammond, H., Metzker, M.L., Todd, J.A., and Hess, J.F. (1998) Cloning of a novel member of the low-density lipoprotein receptor family. Gene 216, 103-111