Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β

Science

Volumn 280, Issue 5363, 1998, Pages 596-599

  Behrens, Jürgen ^a   Jerchow, Boris Alexander ^a   Würtele, Martin ^a   Grimm, Jan ^a   Asbrand, Christian ^a   Wirtz, Ralph ^a   Kühl, Michael ^b   Wedlich, Doris ^b   Birchmeier, Walter ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AXIN; BETA CATENIN; CELL PROTEIN; CONDUCTIN; UNCLASSIFIED DRUG;

ADENOMATOUS POLYP; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; EMBRYO (ANATOMY); NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN STABILITY; TUMOR SUPPRESSOR GENE; XENOPUS;

ADENOMATOUS POLYPOSIS COLI PROTEIN; AMINO ACID SEQUENCE; ANIMALS; BETA CATENIN; BINDING SITES; BODY PATTERNING; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CYTOSKELETAL PROTEINS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION; PROTEINS; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED; XENOPUS; XENOPUS PROTEINS;

EID: 0032562603     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.280.5363.596     Document Type: Article

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38. We thank C. Birchmeier for helpful suggestions to the manuscript, S. Britsch and S. Dietrich for help in the analysis of mouse embryos, V. Brinkmann for help with confocal microscopy, and K. Feller and B. Bradtke for technical assistance. The Xwnt-8 construct was a gift from R. Moon, University of Washington, Seattle, and the siamois construct a gift from P. Lemaire, Institute de Biologie du Developpement de Marseille, France.