A mouse cerberus/Dan-related gene family

Developmental Biology

Volumn 209, Issue 1, 1999, Pages 98-110

  Pearce, Jonathan J H ^a,c   Penny, Graeme ^b   Rossant, Janet ^a  

^a MOUNT SINAI HOSPITAL   (Canada)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c WELLCOME CRC INSTITUTE   (United Kingdom)

Author keywords

Bmp4; Cer1; Cerberus; Dan; Drm; Dte; Embryo; Mouse

Indexed keywords

CANCER GROWTH FACTOR;

AMINO ACID SEQUENCE; ARTICLE; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TUMOR SUPPRESSOR GENE; XENOPUS;

CAENORHABDITIS ELEGANS; CERBERUS; MAMMALIA; RODENTIA; XENOPUS; XENOPUS CERBERUS;

EID: 0033135571     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1999.9240     Document Type: Article

References (63)

1. Altschul S. F., Madden T. L., Schaffer A. A., Zhang J., Zhang Z., Miller W., Lipman D. J. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res. 25:1997;3389-3402.
2. Ang S. L., Conlon R. A., Jin O., Rossant J. Positive and negative signals from mesoderm regulate the expression of mouse Otx2 in ectoderm explants. Development. 120:1994;2979-2989.
3. Attwood T. K., Beck M. E., Flower D. R., Scordis P., Selley J. N. The PRINTS protein fingerprint database in its fifth year. Nucleic Acids Res. 26:1998;304-308.
4. Bellomo D., Lander A., Harragan I., Brown N. A. Cell proliferation in mammalian gastrulation: The ventral node and notochord are relatively quiescent. Dev. Dyn. 205:1996;471-485.
5. Belo J. A., Bouwmeester T., Leyns L., Kertesz N., Gallo M., Follettie M., De Robertis E. M. Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula. Mech. Dev. 68:1997;45-57.
6. Berger W., Meindl A., van de Pol T. J., Cremers F. P., Ropers H. H., Doerner C., Monaco A., Bergen A. A., Lebo R., Warburg M. Isolation of a candidate gene for Norrie disease by positional cloning. Nat. Genet. 1:1992;199-203.
7. Biben C., Stanley E., Fabri L., Kotecha S., Rhinn M., Drinkwater C., Lah M., Wang C. C., Nash A., Hilton D., Ang S. L., Mohun T., Harvey R. P. Murine cerberus homologue mCer-1: A candidate anterior patterning molecule. Dev. Biol. 194:1998;135-151.
8. Bonthron D., Orr E. C., Mitsock L. M., Ginsburg D., Handin R. I., Orkin S. H. Nucleotide sequence of pre-pro-von Willebrand factor cDNA. Nucleic Acids Res. 14:1986;7125-7127.
9. Bouwmeester T., Kim S., Sasai Y., Lu B., De Robertis E. M. Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer. Nature. 382:1996;595-601.
10. Chen Z. Y., Hendriks R. W., Jobling M. A., Powell J. F., Breakefield X. O., Sims K. B., Craig I. W. Isolation and characterization of a candidate gene for Norrie disease. Nat. Genet. 1:1992;204-208.
11. Collignon J., Varlet I., Robertson E. J. Relationship between asymmetric nodal expression and the direction of embryonic turning. Nature. 381:1996;155-158.
12. Conlon F. L., Lyons K. M., Takaesu N., Barth K. S., Kispert A., Herrmann B., Robertson E. J. A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. Development. 120:1994;1919-1928.
13. Conlon R. A., Rossant J. Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo. Development. 116:1992;357-368.
14. Cravchik A., Matus A. A novel strategy for the immunological tagging of cDNA constructs. Gene. 137:1993;139-143.
15. Downs K. M., Davies T. Staging of gastrulating mouse embryos by morphological landmarks in the dissecting microscope. Development. 118:1993;1255-1266.
16. Dufort D., Schwartz L., Harpal K., Rossant J. The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis. Development. 125:1998;3015-3025.
17. Ferrari D., Lichtler A. C., Pan Z. Z., Dealy C. N., Upholt W. B., Kosher R. A. Ectopic expression of Msx-2 in posterior limb bud mesoderm impairs limb morphogenesis while inducing BMP-4 expression, inhibiting cell proliferation, and promoting apoptosis. Dev. Biol. 197:1998;12-24.
18. Field J., Nikawa J., Broek D., MacDonald B., Rodgers L., Wilson I. A., Lerner R. A., Wigler M. Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method. Mol. Cell. Biol. 8:1988;2159-2165.
19. Gentry L. E., Lioubin M. N., Purchio A. F., Marquardt H. Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide. Mol. Cell. Biol. 8:1988;4162-4168.
20. Glinka A., Wu W., Delius H., Monaghan A. P., Blumenstock C., Niehrs C. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature. 391:1998;357-362.
21. Glinka A., Wu W., Onichtchouk D., Blumenstock C., Niehrs C. Head induction by simultaneous repression of Bmp and Wnt signalling in Xenopus. Nature. 389:1997;517-519.
22. Gum J. R. Jr., Hicks J. W., Toribara N. W., Siddiki B., Kim Y. S. Molecular cloning of human intestinal mucin (MUC2) cDNA. Identification of the amino terminus and overall sequence similarity to prepro-von Willebrand factor. J. Biol. Chem. 269:1994;2440-2446.
23. Henrique D., Adam J., Myat A., Chitnis A., Lewis J., Ish-Horowicz D. Expression of a Delta homologue in prospective neurons in the chick. Nature. 375:1995;787-790.
24. Hirsinger E., Duprez D., Jouve C., Malapert P., Cooke J., Pourquie O. Noggin acts downstream of Wnt and Sonic hedgehog to antagonize BMP4 in avian somite patterning. Development. 124:1997;4605-4614.
25. Hsu D. R., Economides A. N., Wang X., Eimon P. M., Harland R. M. The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Mol. Cell. 1:1998;673-683.
26. Jernvall J., Aberg T., Kettunen P., Keranen S., Thesleff I. The life history of an embryonic signaling center: BMP-4 induces p21 and is associated with apoptosis in the mouse tooth enamel knot. Development. 125:1998;161-169.
27. Jones C. M., Kuehn M. R., Hogan B. L., Smith J. C., Wright C. V. Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. Development. 121:1995;3651-3662.
28. Joseph E. M., Melton D. A. Xnr4: AXenopus. Dev. Biol. 184:1997;367-372.
29. Kispert A., Herrmann B. G. Immunohistochemical analysis of the Brachyury protein in wild-type and mutant mouse embryos. Dev. Biol. 161:1994;179-193.
30. Krause M., Hirsh D. A trans-spliced leader sequence on actin mRNA in C. elegans. Cell. 49:1987;753-761.
31. Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
32. Lamb T. M., Knecht A. K., Smith W. C., Stachel S. E., Economides A. N., Stahl N., Yancopolous G. D., Harland R. M. Neural induction by the secreted polypeptide noggin. Science. 262:1993;713-718.
33. Levin M., Johnson R. L., Stern C. D., Kuehn M., Tabin C. A molecular pathway determining left-right asymmetry in chick embryogenesis. Cell. 82:1995;803-814.
34. Levin M., Pagan S., Roberts D. J., Cooke J., Kuehn M. R., Tabin C. J. Left/right patterning signals and the independent regulation of different aspects of situs in the chick embryo. Dev. Biol. 189:1997;57-67.
35. Lowe L. A., Supp D. M., Sampath K., Yokoyama T., Wright C. V., Potter S. S., Overbeek P., Kuehn M. R. Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus. Nature. 381:1996;158-161.
36. Macias-Silva M., Abdollah S., Hoodless P. A., Pirone R., Attisano L., Wrana J. L. MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling. Cell. 87:1996;1215-1224.
37. Marcelle C., Stark M. R., Bronner-Fraser M. Coordinate actions of BMPs, Wnts, Shh and noggin mediate patterning of the dorsal somite. Development. 124:1997;3955-3963.
38. McBurney M. W., Rogers B. J. Isolation of male embryonal carcinoma cells and their chromosome replication patterns. Dev. Biol. 89:1982;503-508.
39. McDonald N. Q., Hendrickson W. A. A structural superfamily of growth factors containing a cystine knot motif. Cell. 73:1993;421-424.
40. Meitinger T., Meindl A., Bork P., Rost B., Sander C., Haasemann M., Murken J. Molecular modelling of the Norrie disease protein predicts a cystine knot growth factor tertiary structure. Nat. Genet. 5:1993;376-380.
41. Meno C., Ito Y., Saijoh Y., Matsuda Y., Tashiro K., Kuhara S., Hamada H. Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: Their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos. Genes Cells. 2:1997;513-524.
42. Minabe-Saegusa C., Saegusa H., Tsukahara M., Noguchi S. Sequence and expression of a novel mouse gene PRDC (protein related to DAN and cerberus) identified by a gene trap approach. Dev. Growth Differ. 40:1998;343-353.
43. Nakamura Y., Ozaki T., Nakagawara A., Sakiyama S. A product of DAN, a novel candidate tumour suppressor gene, is secreted into culture medium and suppresses DNA synthesis. Eur. J. Cancer. 33:1997;1986-1990.
44. Nielsen H., Engelbrecht J., Brunak S., von Heijne G. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng. 10:1997;1-6.
45. Oulad-Abdelghani M., Chazaud C., Bouillet P., Mattei M. G., Dolle P., Chambon P. Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily. Int. J. Dev. Biol. 42:1998;23-32.
46. Ozaki T., Ma J., Takenaga K., Sakiyama S. Cloning of mouse DAN cDNA and its down-regulation in transformed cells. Jpn. J. Cancer Res. 87:1996;58-61.
47. Ozaki T., Sakiyama S. Molecular cloning and characterization of a cDNA showing negative regulation in v-src-transformed 3Y1 rat fibroblasts. Proc. Natl. Acad. Sci. USA. 90:1993;2593-2597.
48. Ozaki T., Sakiyama S. Tumor-suppressive activity of N03 gene product in v-src-transformed rat 3Y1 fibroblasts. Cancer Res. 54:1994;646-648.
49. Pagan-Westphal S. M., Tabin C. J. The transfer of left-right positional information during chick embryogenesis. Cell. 93:1998;25-35.
50. Parker S. B., Eichele G., Zhang P., Rawls A., Sands A. T., Bradley A., Olson E. N., Harper J. W., Elledge S. J. p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science. 267:1995;1024-1027.
51. Piccolo S., Sasai Y., Lu B., De Robertis E. M. Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4. Cell. 86:1996;589-598.
52. Quinlan G. A., Williams E. A., Tan S. S., Tam P. P. Neuroectodermal fate of epiblast cells in the distal region of the mouse egg cylinder: Implication for body plan organization during early embryogenesis. Development. 121:1995;87-98.
53. Reshef R., Maroto M., Lassar A. B. Regulation of dorsal somitic cell fates: BMPs and Noggin control the timing and pattern of myogenic regulator expression. Genes Dev. 12:1998;290-303.
54. Sampath K., Cheng A. M., Frisch A., Wright C. V. Functional differences among Xenopus nodal-related genes in left-right axis determination. Development. 124:1997;3293-3302.
55. Sasai Y., Lu B., Steinbeisser H., De Robertis E. M. Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature. 376:1995;333-336.
56. Smith W. C., McKendry R., Ribisi S. Jr., Harland R. M. A nodal-related gene defines a physical and functional domain within the Spemann organizer. Cell. 82:1995;37-46.
57. Tang S. J., Hoodless P. A., Lu Z., Breitman M. L., McInnes R. R., Wrana J. L., Buchwald M. The Tlx-2 homeobox gene is a downstream target of BMP signalling and is required for mouse mesoderm development. Development. 125:1998;1877-1887.
58. Thomas P., Beddington R. Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo. Curr. Biol. 6:1996;1487-1496.
59. Thomas P. Q., Brown A., Beddington R. S. Hex: A homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors. Development. 125:1998;85-94.
60. Topol L. Z., Marx M., Laugier D., Bogdanova N. N., Boubnov N. V., Clausen P. A., Calothy G., Blair D. G. Identification of drm, a novel gene whose expression is suppressed in transformed cells and which can inhibit growth of normal but not transformed cells in culture. Mol. Cell. Biol. 17:1997;4801-4810.
61. Waldrip W. R., Bikoff E. K., Hoodless P. A., Wrana J. L., Robertson E. J. Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo. Cell. 92:1998;797-808.
62. Zhou X., Sasaki H., Lowe L., Hogan B. L., Kuehn M. R. Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation. Nature. 361:1993;543-547.
63. Zimmerman L. B., De Jesus-Escobar J. M., Harland R. M. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell. 86:1996;599-606.