메뉴 건너뛰기




Volumn 13, Issue 14, 1999, Pages 1768-1773

Wnt-induced dephosphorylation of Axin releases β-catenin from the Axin complex

Author keywords

Axin complex; Phosphorylation; Wnt signaling; catenin

Indexed keywords

AXIN; BETA CATENIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 0033565533     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.13.14.1768     Document Type: Article
Times cited : (309)

References (29)
  • 1
    • 0030978351 scopus 로고    scopus 로고
    • β-catenin is a target for the ubiquitin-proteasome pathway
    • Aberle, H., A. Bauer, J. Stappert, A. Kispert, and R. Kemler. 1997. β-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 16: 3797-3804.
    • (1997) EMBO J. , vol.16 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3    Kispert, A.4    Kemler, R.5
  • 3
    • 0032054828 scopus 로고    scopus 로고
    • Wnt signaling: Why is everything so negative?
    • Brown, J.D. and R.T. Moon. 1998. Wnt signaling: Why is everything so negative? Curr. Opin. Cell Biol. 10: 182-187.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 182-187
    • Brown, J.D.1    Moon, R.T.2
  • 4
    • 0031456158 scopus 로고    scopus 로고
    • Wnt signaling: A common theme in animal development
    • Cadigan, K.M. and R. Nusse. 1997. Wnt signaling: A common theme in animal development. Genes & Dev. 11: 3286-3305.
    • (1997) Genes & Dev. , vol.11 , pp. 3286-3305
    • Cadigan, K.M.1    Nusse, R.2
  • 5
    • 0029811434 scopus 로고    scopus 로고
    • Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase c
    • Cook, D., M.J. Fry, K. Hughes, R. Sumathipala, J.R. Woodgett, and T.C. Dale. 1996. Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase c. EMBO J. 15: 4526-4536.
    • (1996) EMBO J. , vol.15 , pp. 4526-4536
    • Cook, D.1    Fry, M.J.2    Hughes, K.3    Sumathipala, R.4    Woodgett, J.R.5    Dale, T.C.6
  • 6
    • 0032492954 scopus 로고    scopus 로고
    • Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK-3β
    • Hart, M.J., R. de los Santos, I.N. Albert, B. Rubinfeld, and P. Polakis. 1998. Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK-3β. Curr. Biol. 8: 573-581.
    • (1998) Curr. Biol. , vol.8 , pp. 573-581
    • Hart, M.J.1    De los Santos, R.2    Albert, I.N.3    Rubinfeld, B.4    Polakis, P.5
  • 7
    • 0031149476 scopus 로고    scopus 로고
    • Activation of the wnt signaling pathway: A molecular mechanism for lithium action
    • Hedgepeth, CM., L.J. Conrad, J. Zhang, H.C. Huang, V.M.Y. Lee, and P.S. Klein. 1997. Activation of the wnt signaling pathway: A molecular mechanism for lithium action. Dev. Biol. 185: 82-91.
    • (1997) Dev. Biol. , vol.185 , pp. 82-91
    • Hedgepeth, C.M.1    Conrad, L.J.2    Zhang, J.3    Huang, H.C.4    Lee, V.M.Y.5    Klein, P.S.6
  • 8
    • 0033524929 scopus 로고    scopus 로고
    • Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain
    • Hsu, W., L. Zeng, and F. Costantini. 1999. Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain. J. Biol. Chem. 274: 3439-3445.
    • (1999) J. Biol. Chem. , vol.274 , pp. 3439-3445
    • Hsu, W.1    Zeng, L.2    Costantini, F.3
  • 9
    • 0032473355 scopus 로고    scopus 로고
    • Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin
    • Ikeda, S., S. Kishida, H. Yamamoto, H. Murai, S. Koyama, and A. Kikuchi. 1998. Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin. EMBO J. 17: 1371-1384.
    • (1998) EMBO J. , vol.17 , pp. 1371-1384
    • Ikeda, S.1    Kishida, S.2    Yamamoto, H.3    Murai, H.4    Koyama, S.5    Kikuchi, A.6
  • 10
    • 0032493042 scopus 로고    scopus 로고
    • Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and β-catenin
    • Itoh, K., V.E. Krupnik, and S.Y. Sokol. 1998. Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and β-catenin. Curr Biol. 8: 591-594.
    • (1998) Curr Biol. , vol.8 , pp. 591-594
    • Itoh, K.1    Krupnik, V.E.2    Sokol, S.Y.3
  • 12
    • 0032079884 scopus 로고    scopus 로고
    • Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of β-catenin
    • Kishida, S., H. Yamamoto, S. Ikeda, M. Kishida, I. Sakamoto, S. Koyama, and A. Kikuchi. 1998. Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of β-catenin. J. Biol. Chem. 273: 10823-10826.
    • (1998) J. Biol. Chem. , vol.273 , pp. 10823-10826
    • Kishida, S.1    Yamamoto, H.2    Ikeda, S.3    Kishida, M.4    Sakamoto, I.5    Koyama, S.6    Kikuchi, A.7
  • 13
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • Klein, P.S. and D.A. Melton. 1996. A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. 93: 8455-8459.
    • (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 15
    • 0033106149 scopus 로고    scopus 로고
    • A ubiquitin ligase complex essential for the NF-κB, Wnt/Wingless, and Hedgehog signaling pathways
    • Maniatis, T. 1999. A ubiquitin ligase complex essential for the NF-κB, Wnt/Wingless, and Hedgehog signaling pathways. Genes & Dev. 13: 505-510.
    • (1999) Genes & Dev. , vol.13 , pp. 505-510
    • Maniatis, T.1
  • 16
  • 17
    • 0031813650 scopus 로고    scopus 로고
    • Axin, an inhibitor of the Wnt signalling pathway, interacts with β-catenin, GSK-3β and APC and reduces the β-catenin level
    • Nakamura, T., F. Hamada, T. Ishidate, K. Anai, K. Kawahara, K. Toyoshima, and T. Akiyama. 1998. Axin, an inhibitor of the Wnt signalling pathway, interacts with β-catenin, GSK-3β and APC and reduces the β-catenin level. Genes Cells 3: 395-403.
    • (1998) Genes Cells , vol.3 , pp. 395-403
    • Nakamura, T.1    Hamada, F.2    Ishidate, T.3    Anai, K.4    Kawahara, K.5    Toyoshima, K.6    Akiyama, T.7
  • 18
    • 0033054464 scopus 로고    scopus 로고
    • The oncogenic activation of β-catenin
    • Polakis, P. 1999. The oncogenic activation of β-catenin. Curr. Opin. Genet. Dev. 9: 15-21.
    • (1999) Curr. Opin. Genet. Dev. , vol.9 , pp. 15-21
    • Polakis, P.1
  • 19
    • 0029664368 scopus 로고    scopus 로고
    • Binding of GSK-3β to the APC-β-catenin complex and regulation of complex assembly
    • Rubinfeld, B., I. Albert, E. Porfiri, C. Fiol, S. Munemitsu, and P. Polakis. 1996. Binding of GSK-3β to the APC-β-catenin complex and regulation of complex assembly. Science 272: 1023-1026.
    • (1996) Science , vol.272 , pp. 1023-1026
    • Rubinfeld, B.1    Albert, I.2    Porfiri, E.3    Fiol, C.4    Munemitsu, S.5    Polakis, P.6
  • 20
  • 21
    • 0032539945 scopus 로고    scopus 로고
    • Bridging of β-catenin and glycogen synthase kinase-3β by axin and inhibition of β-catenin-mediated transcription
    • Sakanaka, C., J.B. Weiss, and L.T. Williams. 1998. Bridging of β-catenin and glycogen synthase kinase-3β by axin and inhibition of β-catenin-mediated transcription. Proc. Natl. Acad. Sci. 95: 3020-3023.
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , pp. 3020-3023
    • Sakanaka, C.1    Weiss, J.B.2    Williams, L.T.3
  • 22
    • 0033605639 scopus 로고    scopus 로고
    • Regulation of β-catenin signaling by the B56 subunit of protein phosphatase 2A
    • Seeling, J.M., J.R. Miller, R. Gil, R.T. Moon, R. White, and D.M. Virshup. 1999. Regulation of β-catenin signaling by the B56 subunit of protein phosphatase 2A. Science 283: 2089-2091.
    • (1999) Science , vol.283 , pp. 2089-2091
    • Seeling, J.M.1    Miller, J.R.2    Gil, R.3    Moon, R.T.4    White, R.5    Virshup, D.M.6
  • 24
    • 0030449964 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells
    • Stambolic, V., L. Ruel, and J.R. Woodgett. 1996. Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells. Curr. Biol. 6: 1664-1668.
    • (1996) Curr. Biol. , vol.6 , pp. 1664-1668
    • Stambolic, V.1    Ruel, L.2    Woodgett, J.R.3
  • 25
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signalling in development
    • Wodarz, A. and R. Nusse. 1998. Mechanisms of Wnt signalling in development. Annu. Rev. Cell Biol. 14: 59-88.
    • (1998) Annu. Rev. Cell Biol. , vol.14 , pp. 59-88
    • Wodarz, A.1    Nusse, R.2
  • 26
    • 0031943002 scopus 로고    scopus 로고
    • Axil, a member of the Axin family, interacts with both glycogen synthase kinase-3β and β-catenin and inhibits axis formation of Xenopus embryos
    • Yamamoto, H., S. Kishida, T. Uochi, S. Ikeda, S. Koyama, M. Asashima, and A. Kikuchi. 1998. Axil, a member of the Axin family, interacts with both glycogen synthase kinase-3β and β-catenin and inhibits axis formation of Xenopus embryos. Mol. Cell. Biol. 18: 2867-2875.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2867-2875
    • Yamamoto, H.1    Kishida, S.2    Uochi, T.3    Ikeda, S.4    Koyama, S.5    Asashima, M.6    Kikuchi, A.7
  • 27
    • 0033574527 scopus 로고    scopus 로고
    • Phosphorylation of Axin, a Wnt signal negative regulator, by glycogen synthase kinase-3β regulates its stability
    • Yamamoto, H., S. Kishida, M. Kishida, S. Ikeda, S. Takada, and A. Kikuchi. 1999. Phosphorylation of Axin, a Wnt signal negative regulator, by glycogen synthase kinase-3β regulates its stability. J. Biol Chem. 274: 10681-10684.
    • (1999) J. Biol Chem. , vol.274 , pp. 10681-10684
    • Yamamoto, H.1    Kishida, S.2    Kishida, M.3    Ikeda, S.4    Takada, S.5    Kikuchi, A.6
  • 28
    • 0029683606 scopus 로고    scopus 로고
    • The axis-inducing activity, stability, and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
    • Yost, C., M. Torres, J. Miller, E. Huang, D. Kimelman, and R. Moon. 1996. The axis-inducing activity, stability, and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes & Dev. 10: 1443-1454.
    • (1996) Genes & Dev. , vol.10 , pp. 1443-1454
    • Yost, C.1    Torres, M.2    Miller, J.3    Huang, E.4    Kimelman, D.5    Moon, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.