-
1
-
-
0037231580
-
Insulin-like growth factor-1 (IGF-1) and aging: Controversies and new insights
-
Bartke A., Chandrashekar V., Dominici F., Turyn D., Kinney B., Steger R., et al. Insulin-like growth factor-1 (IGF-1) and aging: controversies and new insights. Biogerontology. 4:2003;1-8
-
(2003)
Biogerontology
, vol.4
, pp. 1-8
-
-
Bartke, A.1
Chandrashekar, V.2
Dominici, F.3
Turyn, D.4
Kinney, B.5
Steger, R.6
-
2
-
-
0037470488
-
Evolutionary medicine: From dwarf model systems to healthy centenarians?
-
Longo V.D., Finch C.E. Evolutionary medicine: from dwarf model systems to healthy centenarians? Science. 299:2003;1342-1346
-
(2003)
Science
, vol.299
, pp. 1342-1346
-
-
Longo, V.D.1
Finch, C.E.2
-
3
-
-
0038408513
-
Hormonal regulation of aging and life span
-
Brown-Borg H.M. Hormonal regulation of aging and life span. Trends Endocrinol. Metab. 14:2003;151-153
-
(2003)
Trends Endocrinol. Metab.
, vol.14
, pp. 151-153
-
-
Brown-Borg, H.M.1
-
4
-
-
0037410568
-
A low-fat, whole-food vegan diet, as well as other strategies that down-regulate IGF-I activity, may slow the human aging process
-
McCarty M.F. A low-fat, whole-food vegan diet, as well as other strategies that down-regulate IGF-I activity, may slow the human aging process. Med. Hypotheses. 60:2003;784-792
-
(2003)
Med. Hypotheses
, vol.60
, pp. 784-792
-
-
McCarty, M.F.1
-
5
-
-
0036973848
-
Effect of diet and exercise on serum insulin, IGF-I, and IGFBP-1 levels and growth of LNCaP cells in vitro (United States)
-
Ngo T.H., Barnard R.J., Tymchuk C.N., Cohen P., Aronson W.J. Effect of diet and exercise on serum insulin, IGF-I, and IGFBP-1 levels and growth of LNCaP cells in vitro (United States). Cancer Causes Control. 13:2002;929-935
-
(2002)
Cancer Causes Control
, vol.13
, pp. 929-935
-
-
Ngo, T.H.1
Barnard, R.J.2
Tymchuk, C.N.3
Cohen, P.4
Aronson, W.J.5
-
6
-
-
0002991969
-
Life span is increased in rats supplemented with a chromium-pyridine-2- carboxylate complex
-
Evans G.W., Meyer L.K. Life span is increased in rats supplemented with a chromium-pyridine-2-carboxylate complex. Adv. Sci. Res. 1:1994;19-23
-
(1994)
Adv. Sci. Res.
, vol.1
, pp. 19-23
-
-
Evans, G.W.1
Meyer, L.K.2
-
7
-
-
0027494097
-
Homologous physiological effects of phenformin and chromium picolinate
-
McCarty M.F. Homologous physiological effects of phenformin and chromium picolinate. Med. Hypotheses. 41:1993;316-324
-
(1993)
Med. Hypotheses
, vol.41
, pp. 316-324
-
-
McCarty, M.F.1
-
8
-
-
0030895378
-
Insulin exposure and aging theory
-
Parr T. Insulin exposure and aging theory. Gerontology. 43:1997;182-200
-
(1997)
Gerontology
, vol.43
, pp. 182-200
-
-
Parr, T.1
-
9
-
-
0031007065
-
The AMP-activated protein kinase-fuel gauge of the mammalian cell?
-
Hardie D.G., Carling D. The AMP-activated protein kinase-fuel gauge of the mammalian cell? Eur. J. Biochem. 246:1997;259-273
-
(1997)
Eur. J. Biochem.
, vol.246
, pp. 259-273
-
-
Hardie, D.G.1
Carling, D.2
-
10
-
-
85047689953
-
5-Aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?
-
Corton J.M., Gillespie J.G., Hawley S.A., Hardie D.G. 5-Aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? Eur. J. Biochem. 229:1995;558-565
-
(1995)
Eur. J. Biochem.
, vol.229
, pp. 558-565
-
-
Corton, J.M.1
Gillespie, J.G.2
Hawley, S.A.3
Hardie, D.G.4
-
11
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G., Myers R., Li Y., Chen Y., Shen X., Fenyk-Melody J., et al. Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest. 108:2001;1167-1174
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
-
12
-
-
0036299982
-
Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes
-
Musi N., Hirshman M.F., Nygren J., Svanfeldt M., Bavenholm P., Rooyackers O., et al. Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes. Diabetes. 51:2002;2074-2081
-
(2002)
Diabetes
, vol.51
, pp. 2074-2081
-
-
Musi, N.1
Hirshman, M.F.2
Nygren, J.3
Svanfeldt, M.4
Bavenholm, P.5
Rooyackers, O.6
-
13
-
-
0036324142
-
The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism
-
Hawley S.A., Gadalla A.E., Olsen G.S., Hardie D.G. The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism. Diabetes. 51:2002;2420-2425
-
(2002)
Diabetes
, vol.51
, pp. 2420-2425
-
-
Hawley, S.A.1
Gadalla, A.E.2
Olsen, G.S.3
Hardie, D.G.4
-
14
-
-
0037067666
-
The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways
-
Fryer L.G., Parbu-Patel A., Carling D. The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways. J. Biol. Chem. 277:2002;25226-25232
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25226-25232
-
-
Fryer, L.G.1
Parbu-Patel, A.2
Carling, D.3
-
15
-
-
0034863102
-
Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase
-
Zheng D., MacLean P.S., Pohnert S.C., Knight J.B., Olson A.L., Winder W.W., et al. Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase. J. Appl. Physiol. 91:2001;1073-1083
-
(2001)
J. Appl. Physiol.
, vol.91
, pp. 1073-1083
-
-
Zheng, D.1
MacLean, P.S.2
Pohnert, S.C.3
Knight, J.B.4
Olson, A.L.5
Winder, W.W.6
-
16
-
-
0037379283
-
Effects of AICAR and exercise on insulin-stimulated glucose uptake, signaling, and GLUT-4 content in rat muscles
-
Jessen N., Pold R., Buhl E.S., Jensen L.S., Schmitz O., Lund S. Effects of AICAR and exercise on insulin-stimulated glucose uptake, signaling, and GLUT-4 content in rat muscles. J. Appl. Physiol. 94:2003;1373-1379
-
(2003)
J. Appl. Physiol.
, vol.94
, pp. 1373-1379
-
-
Jessen, N.1
Pold, R.2
Buhl, E.S.3
Jensen, L.S.4
Schmitz, O.5
Lund, S.6
-
17
-
-
85047685583
-
Effect of metformin on insulin-like growth factor (IGF) I and IGF-binding protein I in polycystic ovary syndrome
-
De L.V., la Marca A., Orvieto R., Morgante G. Effect of metformin on insulin-like growth factor (IGF) I and IGF-binding protein I in polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 85:2000;1598-1600
-
(2000)
J. Clin. Endocrinol. Metab.
, vol.85
, pp. 1598-1600
-
-
De L., V.1
La Marca, A.2
Orvieto, R.3
Morgante, G.4
-
18
-
-
0036113811
-
Short-term treatment with metformin decreases serum leptin concentration without affecting body weight and body fat content in normal-weight healthy men
-
Fruehwald-Schultes B., Oltmanns K.M., Toschek B., Sopke S., Kern W., Born J., et al. Short-term treatment with metformin decreases serum leptin concentration without affecting body weight and body fat content in normal-weight healthy men. Metabolism. 51:2002;531-536
-
(2002)
Metabolism
, vol.51
, pp. 531-536
-
-
Fruehwald-Schultes, B.1
Oltmanns, K.M.2
Toschek, B.3
Sopke, S.4
Kern, W.5
Born, J.6
-
19
-
-
0038584871
-
Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression
-
da S.X., Leclerc X., Varadi I., Tsuboi A., Moule T., Rutter S.K. Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression. Biochem. J. 371:2003;761-774
-
(2003)
Biochem. J.
, vol.371
, pp. 761-774
-
-
Da, S.X.1
Leclerc, X.2
Varadi, I.3
Tsuboi, A.4
Moule, T.5
Rutter, S.K.6
-
20
-
-
0026004859
-
Nutrition and somatomedin. XXVI. Molecular regulation of IGF-I by insulin in cultured rat hepatocytes
-
Phillips L.S., Goldstein S., Pao C.I. Nutrition and somatomedin. XXVI. Molecular regulation of IGF-I by insulin in cultured rat hepatocytes. Diabetes. 40:1991;1525-1530
-
(1991)
Diabetes
, vol.40
, pp. 1525-1530
-
-
Phillips, L.S.1
Goldstein, S.2
Pao, C.I.3
-
21
-
-
0027944977
-
Insulin-like growth factor binding proteins in the human circulation: A review
-
Baxter R.C. Insulin-like growth factor binding proteins in the human circulation: a review. Horm Res. 42:1994;140-144
-
(1994)
Horm Res.
, vol.42
, pp. 140-144
-
-
Baxter, R.C.1
-
22
-
-
0034811830
-
Stimulation of IGF-binding protein-1 secretion by AMP-activated protein kinase
-
Lewitt M.S. Stimulation of IGF-binding protein-1 secretion by AMP-activated protein kinase. Biochem. Biophys. Res. Commun. 282:2001;1126-1131
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.282
, pp. 1126-1131
-
-
Lewitt, M.S.1
-
23
-
-
0029133235
-
Metabolic effects of metformin in non-insulin-dependent diabetes mellitus
-
Stumvoll M., Nurjhan N., Perriello G., Dailey G., Gerich J.E. Metabolic effects of metformin in non-insulin-dependent diabetes mellitus. N. Engl. J. Med. 333:1995;550-554
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 550-554
-
-
Stumvoll, M.1
Nurjhan, N.2
Perriello, G.3
Dailey, G.4
Gerich, J.E.5
-
24
-
-
9544247850
-
The effect of metformin on the metabolic abnormalities associated with upper-body fat distribution. BIGPRO Study Group
-
Fontbonne A., Charles M.A., Juhan-Vague I., Bard J.M., Andre P., Isnard F., et al. The effect of metformin on the metabolic abnormalities associated with upper-body fat distribution. BIGPRO Study Group. Diabetes Care. 19:1996;920-926
-
(1996)
Diabetes Care
, vol.19
, pp. 920-926
-
-
Fontbonne, A.1
Charles, M.A.2
Juhan-Vague, I.3
Bard, J.M.4
Andre, P.5
Isnard, F.6
-
25
-
-
0031614038
-
Metformin decreases food consumption and induces weight loss in subjects with obesity with type II non-insulin-dependent diabetes
-
Lee A., Morley J.E. Metformin decreases food consumption and induces weight loss in subjects with obesity with type II non-insulin-dependent diabetes. Obes. Res. 6:1998;47-53
-
(1998)
Obes. Res.
, vol.6
, pp. 47-53
-
-
Lee, A.1
Morley, J.E.2
-
26
-
-
17744400090
-
Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome
-
Pasquali R., Gambineri A., Biscotti D., Vicennati V., Gagliardi L., Colitta D., et al. Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 85:2000;2767-2774
-
(2000)
J. Clin. Endocrinol. Metab.
, vol.85
, pp. 2767-2774
-
-
Pasquali, R.1
Gambineri, A.2
Biscotti, D.3
Vicennati, V.4
Gagliardi, L.5
Colitta, D.6
-
27
-
-
0035655494
-
Beneficial effects of metformin in normoglycemic morbidly obese adolescents
-
Kay J.P., Alemzadeh R., Langley G., D'Angelo L., Smith P., Holshouser S. Beneficial effects of metformin in normoglycemic morbidly obese adolescents. Metabolism. 50:2001;1457-1461
-
(2001)
Metabolism
, vol.50
, pp. 1457-1461
-
-
Kay, J.P.1
Alemzadeh, R.2
Langley, G.3
D'Angelo, L.4
Smith, P.5
Holshouser, S.6
-
28
-
-
0035205980
-
Metformin and carbohydrate-modified diet: A novel obesity treatment protocol: Preliminary findings from a case series of nondiabetic women with midlife weight gain and hyperinsulinemia
-
Mogul H.R., Peterson S.J., Weinstein B.I., Zhang S., Southren A.L. Metformin and carbohydrate-modified diet: a novel obesity treatment protocol: preliminary findings from a case series of nondiabetic women with midlife weight gain and hyperinsulinemia. Heart Dis. 3:2001;285-292
-
(2001)
Heart Dis.
, vol.3
, pp. 285-292
-
-
Mogul, H.R.1
Peterson, S.J.2
Weinstein, B.I.3
Zhang, S.4
Southren, A.L.5
-
29
-
-
0023896220
-
The low activity of acetyl-CoA carboxylase in basal and glucagon-stimulated hepatocytes is due to phosphorylation by the AMP-activated protein kinase and not cyclic AMP-dependent protein kinase
-
Sim A.T., Hardie D.G. The low activity of acetyl-CoA carboxylase in basal and glucagon-stimulated hepatocytes is due to phosphorylation by the AMP-activated protein kinase and not cyclic AMP-dependent protein kinase. FEBS Lett. 233:1988;294-298
-
(1988)
FEBS Lett.
, vol.233
, pp. 294-298
-
-
Sim, A.T.1
Hardie, D.G.2
-
30
-
-
15444339308
-
Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase a
-
Winder W.W., Wilson H.A., Hardie D.G., Rasmussen B.B., Hutber C.A., Call G.B., et al. Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A. J. Appl. Physiol. 82:1997;219-225
-
(1997)
J. Appl. Physiol.
, vol.82
, pp. 219-225
-
-
Winder, W.W.1
Wilson, H.A.2
Hardie, D.G.3
Rasmussen, B.B.4
Hutber, C.A.5
Call, G.B.6
-
31
-
-
0028947868
-
Anorectic effect of metformin in obese Zucker rats: Lack of evidence for the involvement of neuropeptide Y
-
Rouru J., Pesonen U., Koulu M., Huupponen R., Santti E., Virtanen K., et al. Anorectic effect of metformin in obese Zucker rats: lack of evidence for the involvement of neuropeptide Y. Eur. J. Pharmacol. 273:1995;99-106
-
(1995)
Eur. J. Pharmacol.
, vol.273
, pp. 99-106
-
-
Rouru, J.1
Pesonen, U.2
Koulu, M.3
Huupponen, R.4
Santti, E.5
Virtanen, K.6
-
32
-
-
0033390614
-
Metformin inhibits catecholamine-stimulated lipolysis in obese, hyperinsulinemic, hypertensive subjects in subcutaneous adipose tissue: An in situ microdialysis study
-
Flechtner-Mors M., Ditschuneit H.H., Jenkinson C.P., Alt A., Adler G. Metformin inhibits catecholamine-stimulated lipolysis in obese, hyperinsulinemic, hypertensive subjects in subcutaneous adipose tissue: an in situ microdialysis study. Diabetic Med. 16:1999;1000-1006
-
(1999)
Diabetic Med.
, vol.16
, pp. 1000-1006
-
-
Flechtner-Mors, M.1
Ditschuneit, H.H.2
Jenkinson, C.P.3
Alt, A.4
Adler, G.5
-
33
-
-
0033820422
-
5-Aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes
-
Salt I.P., Connell J.M., Gould G.W. 5-Aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes. Diabetes. 49:2000;1649-1656
-
(2000)
Diabetes
, vol.49
, pp. 1649-1656
-
-
Salt, I.P.1
Connell, J.M.2
Gould, G.W.3
-
34
-
-
0031881129
-
Further evidence for a central role of adipose tissue in the antihyperglycemic effect of metformin
-
Abbasi F., Carantoni M., Chen Y.D., Reaven G.M. Further evidence for a central role of adipose tissue in the antihyperglycemic effect of metformin. Diabetes Care. 21:1998;1301-1305
-
(1998)
Diabetes Care
, vol.21
, pp. 1301-1305
-
-
Abbasi, F.1
Carantoni, M.2
Chen, Y.D.3
Reaven, G.M.4
-
35
-
-
0031743113
-
Non-esterified fatty acid metabolism and postprandial lipaemia
-
Frayn K.N. Non-esterified fatty acid metabolism and postprandial lipaemia. Atherosclerosis. 141(Suppl 1):1998;S41-S46
-
(1998)
Atherosclerosis
, vol.141
, Issue.SUPPL. 1
-
-
Frayn, K.N.1
-
36
-
-
0034111902
-
Metformin therapy decreases hyperandrogenism and hyperinsulinemia in women with polycystic ovary syndrome
-
Kolodziejczyk B., Duleba A.J., Spaczynski R.Z., Pawelczyk L. Metformin therapy decreases hyperandrogenism and hyperinsulinemia in women with polycystic ovary syndrome. Fertil. Steril. 73:2000;1149-1154
-
(2000)
Fertil. Steril.
, vol.73
, pp. 1149-1154
-
-
Kolodziejczyk, B.1
Duleba, A.J.2
Spaczynski, R.Z.3
Pawelczyk, L.4
-
37
-
-
0035374673
-
Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1- and epidermal growth factor-dependent extracellular signal-regulated kinase pathway
-
Kim J., Yoon M.Y., Choi S.L., Kang I., Kim S.S., Kim Y.S., et al. Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1- and epidermal growth factor-dependent extracellular signal-regulated kinase pathway. J. Biol. Chem. 276:2001;19102-19110
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19102-19110
-
-
Kim, J.1
Yoon, M.Y.2
Choi, S.L.3
Kang, I.4
Kim, S.S.5
Kim, Y.S.6
-
38
-
-
0037025356
-
AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling
-
Bolster D.R., Crozier S.J., Kimball S.R., Jefferson L.S. AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling. J. Biol. Chem. 277:2002;23977-23980
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23977-23980
-
-
Bolster, D.R.1
Crozier, S.J.2
Kimball, S.R.3
Jefferson, L.S.4
-
39
-
-
0037276069
-
A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway
-
Kimura N., Tokunaga C., Dalal S., Richardson C., Yoshino K., Hara K., et al. A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway. Genes Cells. 8:2003;65-79
-
(2003)
Genes Cells
, vol.8
, pp. 65-79
-
-
Kimura, N.1
Tokunaga, C.2
Dalal, S.3
Richardson, C.4
Yoshino, K.5
Hara, K.6
-
41
-
-
0032698075
-
Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
-
Bonni A., Brunet A., West A.E., Datta S.R., Takasu M.A., Greenberg M.E. Cell survival promoted by the Ras-MAPK signaling pathway by transcription- dependent and -independent mechanisms. Science. 286:1999;1358-1362
-
(1999)
Science
, vol.286
, pp. 1358-1362
-
-
Bonni, A.1
Brunet, A.2
West, A.E.3
Datta, S.R.4
Takasu, M.A.5
Greenberg, M.E.6
-
42
-
-
0842304369
-
Mammalian target of rapamycin inhibition as therapy for hematologic malignancies
-
Panwalkar A., Verstovsek S., Giles F.J. Mammalian target of rapamycin inhibition as therapy for hematologic malignancies. Cancer. 100:2004;657-666
-
(2004)
Cancer
, vol.100
, pp. 657-666
-
-
Panwalkar, A.1
Verstovsek, S.2
Giles, F.J.3
-
43
-
-
0035859956
-
P70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD
-
Harada H., Andersen J.S., Mann M., Terada N., Korsmeyer S.J. p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD. Proc. Natl. Acad. Sci. USA. 98:2001;9666-9670
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9666-9670
-
-
Harada, H.1
Andersen, J.S.2
Mann, M.3
Terada, N.4
Korsmeyer, S.J.5
-
44
-
-
0018895934
-
Effect of treatment with phenformin, diphenylhydantoin or L-dopa on life span and tumour incidence in C3H/Sn mice
-
Dilman V.M., Anisimov V.N. Effect of treatment with phenformin, diphenylhydantoin or L-dopa on life span and tumour incidence in C3H/Sn mice. Gerontology. 26:1980;241-246
-
(1980)
Gerontology
, vol.26
, pp. 241-246
-
-
Dilman, V.M.1
Anisimov, V.N.2
-
45
-
-
0018815463
-
Effect of phenformin and miscleron on the blood somatomedin activity level in breast cancer
-
Vasil'eva I.A., Bershtein L.M., Ostroumova M.N., Dil'man V.M. [Effect of phenformin and miscleron on the blood somatomedin activity level in breast cancer]. Vopr. Onkol. 26:1980;34-36
-
(1980)
Vopr. Onkol.
, vol.26
, pp. 34-36
-
-
Vasil'Eva, I.A.1
Bershtein, L.M.2
Ostroumova, M.N.3
Dil'Man, V.M.4
-
46
-
-
0017843134
-
Inhibition of DMBA-induced carcinogenesis by phenformin in the mammary gland of rats
-
Dilman V.M., Berstein L.M., Zabezhinski M.A., Alexandrov V.A., Bobrov J.F., Pliss G.B. Inhibition of DMBA-induced carcinogenesis by phenformin in the mammary gland of rats. Arch. Geschwulstforsc. 48:1978;1-8
-
(1978)
Arch. Geschwulstforsc.
, vol.48
, pp. 1-8
-
-
Dilman, V.M.1
Berstein, L.M.2
Zabezhinski, M.A.3
Alexandrov, V.A.4
Bobrov, J.F.5
Pliss, G.B.6
-
48
-
-
0027428833
-
Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletion
-
Sato R., Goldstein J.L., Brown M.S. Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletion. Proc. Natl. Acad. Sci. USA. 90:1993;9261-9265
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 9261-9265
-
-
Sato, R.1
Goldstein, J.L.2
Brown, M.S.3
-
49
-
-
0041355355
-
Direct activation of AMP-activated protein kinase stimulates nitric oxide synthesis in human aortic endothelial cells
-
Morrow V.A., Foufelle F., Connell J.M., Petrie J.R., Gould G.W., Salt I.P. Direct activation of AMP-activated protein kinase stimulates nitric oxide synthesis in human aortic endothelial cells. J. Biol. Chem. 2003
-
(2003)
J. Biol. Chem.
-
-
Morrow, V.A.1
Foufelle, F.2
Connell, J.M.3
Petrie, J.R.4
Gould, G.W.5
Salt, I.P.6
-
50
-
-
0037328928
-
Malonyl-CoA and AMP-activated protein kinase (AMPK): Possible links between insulin resistance in muscle and early endothelial cell damage in diabetes
-
Ruderman N.B., Cacicedo J.M., Itani S., Yagihashi N., Saha A.K., Ye J.M., et al. Malonyl-CoA and AMP-activated protein kinase (AMPK): possible links between insulin resistance in muscle and early endothelial cell damage in diabetes. Biochem. Soc. Trans. 31:2003;202-206
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 202-206
-
-
Ruderman, N.B.1
Cacicedo, J.M.2
Itani, S.3
Yagihashi, N.4
Saha, A.K.5
Ye, J.M.6
-
51
-
-
0036111682
-
Insulin-like growth factors and cancer
-
Furstenberger G., Senn H.J. Insulin-like growth factors and cancer. Lancet Oncol. 3:2002;298-302
-
(2002)
Lancet Oncol.
, vol.3
, pp. 298-302
-
-
Furstenberger, G.1
Senn, H.J.2
-
52
-
-
0037034257
-
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
-
Knowler W.C., Barrett-Connor E., Fowler S.E., Hamman R.F., Lachin J.M., Walker E.A., et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N. Engl. J. Med. 346:2002;393-403
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 393-403
-
-
Knowler, W.C.1
Barrett-Connor, E.2
Fowler, S.E.3
Hamman, R.F.4
Lachin, J.M.5
Walker, E.A.6
-
54
-
-
0027939533
-
Comparative tolerability profiles of oral antidiabetic agents
-
Krentz A.J., Ferner R.E., Bailey C.J. Comparative tolerability profiles of oral antidiabetic agents. Drug Safety. 11:1994;223-241
-
(1994)
Drug Safety
, vol.11
, pp. 223-241
-
-
Krentz, A.J.1
Ferner, R.E.2
Bailey, C.J.3
-
55
-
-
0034614420
-
Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I
-
El Mir M.Y., Nogueira V., Fontaine E., Averet N., Rigoulet M., Leverve X. Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I. J. Biol. Chem. 275:2000;223-228
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 223-228
-
-
El Mir, M.Y.1
Nogueira, V.2
Fontaine, E.3
Averet, N.4
Rigoulet, M.5
Leverve, X.6
-
56
-
-
0034659785
-
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
-
Owen M.R., Doran E., Halestrap A.P. Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem. J. 348(Pt 3):2000;607-614
-
(2000)
Biochem. J.
, vol.348
, Issue.3 PART
, pp. 607-614
-
-
Owen, M.R.1
Doran, E.2
Halestrap, A.P.3
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