-
1
-
-
0037166274
-
+ levels
-
+ levels. J. Biol. Chem. 277:18881-18890.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18881-18890
-
-
Anderson, R.M.1
Bitterman, K.J.2
Wood, J.G.3
Medvedik, O.4
Cohen, H.5
Lin, S.S.6
Manchester, J.K.7
Gordon, J.I.8
Sinclair, D.A.9
-
2
-
-
0038329323
-
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae
-
Anderson, R. M., K. J. Bitterman, J. G. Wood, O. Medvedik, and D. A. Sinclair. 2003. Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Nature 423:181-185.
-
(2003)
Nature
, vol.423
, pp. 181-185
-
-
Anderson, R.M.1
Bitterman, K.J.2
Wood, J.G.3
Medvedik, O.4
Sinclair, D.A.5
-
3
-
-
0036229718
-
Mutations in Saccharomyces cerevisiae gene SIR2 can have differential effects on in vivo silencing phenotypes and in vitro histone deacetylation activity
-
Armstrong, C. M., M. Kaeberlein, S. I. Imai, and L. Guarente. 2002. Mutations in Saccharomyces cerevisiae gene SIR2 can have differential effects on in vivo silencing phenotypes and in vitro histone deacetylation activity. Mol. Biol. Cell. 13:1427-1438.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 1427-1438
-
-
Armstrong, C.M.1
Kaeberlein, M.2
Imai, S.I.3
Guarente, L.4
-
4
-
-
0004270170
-
-
John Wiley & Sons, Inc., New York, N.Y.
-
Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 2000. Current protocols in molecular biology, vol. 2. John Wiley & Sons, Inc., New York, N.Y.
-
(2000)
Current Protocols in Molecular Biology
, vol.2
-
-
Ausubel, F.M.1
Brent, R.2
Kingston, R.E.3
Moore, D.D.4
Seidman, J.G.5
Smith, J.A.6
Struhl, K.7
-
5
-
-
0037160097
-
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1
-
Bitterman, K. J., R. M. Anderson, H. Y. Cohen, M. Latorre-Esteves, and D. A. Sinclair. 2002. Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J. Biol. Chem. 277:45099-451O7.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45099-45107
-
-
Bitterman, K.J.1
Anderson, R.M.2
Cohen, H.Y.3
Latorre-Esteves, M.4
Sinclair, D.A.5
-
7
-
-
0032579440
-
Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR-mediated gene disruption and other applications
-
Brachmann, C. B., A. Davies, G. J. Cost, E. Caputo, J. Li, P. Hieter, and J. D. Boeke. 1998. Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast 14:115-132.
-
(1998)
Yeast
, vol.14
, pp. 115-132
-
-
Brachmann, C.B.1
Davies, A.2
Cost, G.J.3
Caputo, E.4
Li, J.5
Hieter, P.6
Boeke, J.D.7
-
8
-
-
0028841317
-
The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability
-
Brachmann, C. B., J. M. Sherman, S. E. Devine, E. E. Cameron, L. Pillus, and J. D. Boeke. 1995. The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability. Genes Dev. 9:2888-2902.
-
(1995)
Genes Dev.
, vol.9
, pp. 2888-2902
-
-
Brachmann, C.B.1
Sherman, J.M.2
Devine, S.E.3
Cameron, E.E.4
Pillus, L.5
Boeke, J.D.6
-
9
-
-
0034928760
-
The Sgs1 helicase of Saccharomyces cerevisiae inhibits retrotransposition of Ty1 multimeric arrays
-
Bryk, M., M. Banerjee, D. Conte, Jr., and M. J. Curcio. 2001. The Sgs1 helicase of Saccharomyces cerevisiae inhibits retrotransposition of Ty1 multimeric arrays. Mol. Cell. Biol. 21:5374-5388.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5374-5388
-
-
Bryk, M.1
Banerjee, M.2
Conte Jr., D.3
Curcio, M.J.4
-
10
-
-
0037184938
-
RNA polymerase 1 propagates unidirectional spreading of rDNA silent chromatin
-
Buck, S. W., J. J. Sandmeier, and J. S. Smith. 2002. RNA polymerase 1 propagates unidirectional spreading of rDNA silent chromatin. Cell 111:1003-1014.
-
(2002)
Cell
, vol.111
, pp. 1003-1014
-
-
Buck, S.W.1
Sandmeier, J.J.2
Smith, J.S.3
-
11
-
-
0015218163
-
Inhibition of nicotinamidase by nicotinamide adenine dinucleotide
-
Calbreath, D. F., and J. G. Joshi. 1971. Inhibition of nicotinamidase by nicotinamide adenine dinucleotide. J. Biol. Chem. 246:4334-4339.
-
(1971)
J. Biol. Chem.
, vol.246
, pp. 4334-4339
-
-
Calbreath, D.F.1
Joshi, J.G.2
-
12
-
-
0026512939
-
Multifunctional yeast high-copy number shuttle vectors
-
Christianson, T. W., R. S. Sikorski, M. Dante, J. H. Shero, and P. Hieter. 1992. Multifunctional yeast high-copy number shuttle vectors. Gene 110:119-122.
-
(1992)
Gene
, vol.110
, pp. 119-122
-
-
Christianson, T.W.1
Sikorski, R.S.2
Dante, M.3
Shero, J.H.4
Hieter, P.5
-
13
-
-
0033120871
-
Elimination of replication block protein Fob1 extends the life span of yeast mother cells
-
Defossez, P. A., R. Prusty, M. Kaeberlein, S. J. Lin, P. Ferrigno, P. A. Silver, R. L. Keil, and L. Guarente. 1999. Elimination of replication block protein Fob1 extends the life span of yeast mother cells. Mol. Cell 3:447-455.
-
(1999)
Mol. Cell
, vol.3
, pp. 447-455
-
-
Defossez, P.A.1
Prusty, R.2
Kaeberlein, M.3
Lin, S.J.4
Ferrigno, P.5
Silver, P.A.6
Keil, R.L.7
Guarente, L.8
-
14
-
-
0029893985
-
HST1, a new member of the SIR2 family of genes
-
Derbyshire, M. K., K. G. Weinstock, and J. N. Strathern. 1996. HST1, a new member of the SIR2 family of genes. Yeast 12:631-640.
-
(1996)
Yeast
, vol.12
, pp. 631-640
-
-
Derbyshire, M.K.1
Weinstock, K.G.2
Strathern, J.N.3
-
15
-
-
0035960636
-
Crystal structure and mechanism of catalysis of a pyrazinamidase from Pyrococcus horikoshii
-
Du, X., W. Wang, R. Kim, H. Yakota, H. Nguyen, and S. H. Kim. 2001. Crystal structure and mechanism of catalysis of a pyrazinamidase from Pyrococcus horikoshii. Biochemistry 40:14166-14172.
-
(2001)
Biochemistry
, vol.40
, pp. 14166-14172
-
-
Du, X.1
Wang, W.2
Kim, R.3
Yakota, H.4
Nguyen, H.5
Kim, S.H.6
-
16
-
-
0142149194
-
Plasmid accumulation reduces life span in Saccharomyces cerevisiae
-
Falcon, A. A., and J. P. Aris. 2003. Plasmid accumulation reduces life span in Saccharomyces cerevisiae. J. Biol. Chem. 278:41607-41617.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 41607-41617
-
-
Falcon, A.A.1
Aris, J.P.2
-
17
-
-
0033887456
-
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
-
Frye, R. A. 2000. Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem. Biophys. Res. Commun. 273:793-798.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.273
, pp. 793-798
-
-
Frye, R.A.1
-
18
-
-
0035162698
-
Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p
-
Gasch, A. P., M. Huang, S. Metzner, D. Botstein, S. J. Elledge, and P. O. Brown. 2001. Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p. Mol. Biol. Cell. 12:2987-3003.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2987-3003
-
-
Gasch, A.P.1
Huang, M.2
Metzner, S.3
Botstein, D.4
Elledge, S.J.5
Brown, P.O.6
-
19
-
-
0033637153
-
Genomic expression programs in the response of yeast cells to environmental changes
-
Gasch, A. P., P. T. Spellman, C. M. Kan, O. Carmel-Harel, M. B. Eisen, G. Storz, D. Botstein, and P. O. Brown. 2000. Genomic expression programs in the response of yeast cells to environmental changes. Mol. Biol. Cell. 11:4241-4257.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 4241-4257
-
-
Gasch, A.P.1
Spellman, P.T.2
Kan, C.M.3
Carmel-Harel, O.4
Eisen, M.B.5
Storz, G.6
Botstein, D.7
Brown, P.O.8
-
20
-
-
0035861202
-
The molecular biology of the SIR proteins
-
Gasser, S. M., and M. M. Cockell. 2001. The molecular biology of the SIR proteins. Gene 279:1-16.
-
(2001)
Gene
, vol.279
, pp. 1-16
-
-
Gasser, S.M.1
Cockell, M.M.2
-
21
-
-
0035881504
-
Sir2p exists in two nucleosome-binding complexes with distinct deacetylase activities
-
Ghidelli, S., D. Donze, N. Dhillon, and R. T. Kamakaka, 2001. Sir2p exists in two nucleosome-binding complexes with distinct deacetylase activities. EMBO J. 20:4522-4535.
-
(2001)
EMBO J.
, vol.20
, pp. 4522-4535
-
-
Ghidelli, S.1
Donze, D.2
Dhillon, N.3
Kamakaka, R.T.4
-
22
-
-
0036190727
-
Identification and functional analysis of the Saccharomyces cerevisiae nicotinamidase gene, PNC1
-
Ghislain, M., E. Talla, and J. M. Francois. 2002. Identification and functional analysis of the Saccharomyces cerevisiae nicotinamidase gene, PNC1. Yeast 19:215-224.
-
(2002)
Yeast
, vol.19
, pp. 215-224
-
-
Ghislain, M.1
Talla, E.2
Francois, J.M.3
-
23
-
-
0030978951
-
Localization of Sir2p: The nucleolus as a compartment for silent information regulators
-
Gotta, M., S. Strahl-Bolsinger, H. Renauld, T. Laroche, B. K. Kennedy, M. Grunstein, and S. M. Gasser. 1997. Localization of Sir2p: the nucleolus as a compartment for silent information regulators. EMBO J. 16:3243-3255.
-
(1997)
EMBO J.
, vol.16
, pp. 3243-3255
-
-
Gotta, M.1
Strahl-Bolsinger, S.2
Renauld, H.3
Laroche, T.4
Kennedy, B.K.5
Grunstein, M.6
Gasser, S.M.7
-
24
-
-
0035862199
-
The human histone deacetylase family
-
Gray, S. G., and T. J. Ekstrom. 2001. The human histone deacetylase family. Exp. Cell Res. 262:75-83.
-
(2001)
Exp. Cell Res.
, vol.262
, pp. 75-83
-
-
Gray, S.G.1
Ekstrom, T.J.2
-
25
-
-
0030797585
-
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
-
Gu, W., and R. G. Roeder. 1997. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 90:595-606.
-
(1997)
Cell
, vol.90
, pp. 595-606
-
-
Gu, W.1
Roeder, R.G.2
-
26
-
-
0034193776
-
Sir2 links chromatin silencing, metabolism, and aging
-
Guarente, L. 2000. Sir2 links chromatin silencing, metabolism, and aging. Genes Dev. 14:1021-1026.
-
(2000)
Genes Dev.
, vol.14
, pp. 1021-1026
-
-
Guarente, L.1
-
27
-
-
0036261650
-
Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation
-
Hoppe, G. J., J. C. Tanny, A. D. Rudner, S. A. Gerber, S. Danaie, S. P. Gygi, and D. Moazed. 2002. Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation. Mol. Cell. Biol. 22:4167-4180.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4167-4180
-
-
Hoppe, G.J.1
Tanny, J.C.2
Rudner, A.D.3
Gerber, S.A.4
Danaie, S.5
Gygi, S.P.6
Moazed, D.7
-
28
-
-
0042822279
-
Association of the RENT complex with nontranscribed and coding regions of rDNA and a regional requirement for the replication fork block protein Fob1 in rDNA silencing
-
Huang, J., and D. Moazed. 2003. Association of the RENT complex with nontranscribed and coding regions of rDNA and a regional requirement for the replication fork block protein Fob1 in rDNA silencing. Genes Dev. 17:2162-2176.
-
(2003)
Genes Dev.
, vol.17
, pp. 2162-2176
-
-
Huang, J.1
Moazed, D.2
-
29
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
Imai, S., C. M. Armstrong, M. Kaeberlein, and L. Guarente. 2000. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403:795-800.
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
30
-
-
0033738362
-
An intervention resembling caloric restriction prolongs life span and retards aging in yeast
-
Jiang, J. C., E. Jaruga, M. V. Repnevskaya, and S. M. Jazwinski. 2000. An intervention resembling caloric restriction prolongs life span and retards. aging in yeast. FASEB J. 14:2135-2137.
-
(2000)
FASEB J.
, vol.14
, pp. 2135-2137
-
-
Jiang, J.C.1
Jaruga, E.2
Repnevskaya, M.V.3
Jazwinski, S.M.4
-
31
-
-
0036840502
-
High osmolarity extends life span in Saccharomyces cerevisiae by a mechanism related to calorie restriction
-
Kaeberlein, M., A. A. Andalis, G. R. Fink, and L. Guarente. 2002. High osmolarity extends life span in Saccharomyces cerevisiae by a mechanism related to calorie restriction. Mol. Cell. Biol. 22:8056-8066.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 8056-8066
-
-
Kaeberlein, M.1
Andalis, A.A.2
Fink, G.R.3
Guarente, L.4
-
32
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
Kaeberlein, M., M. McVey, and L. Guarente. 1999. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 13:2570-2580.
-
(1999)
Genes Dev.
, vol.13
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
33
-
-
0036671011
-
A role for the Saccharomyces cerevisiae RENT complex protein Net1 in HMR silencing
-
Kasulke, D., S. Seitz, and A. E. Ehrenhofer-Murray. 2002. A role for the Saccharomyces cerevisiae RENT complex protein Net1 in HMR silencing. Genetics 161:1411-1423.
-
(2002)
Genetics
, vol.161
, pp. 1411-1423
-
-
Kasulke, D.1
Seitz, S.2
Ehrenhofer-Murray, A.E.3
-
34
-
-
0037312020
-
How does calorie restriction work?
-
Koubova, J., and L. Guarente. 2003. How does calorie restriction work? Genes Dev. 17:313-321.
-
(2003)
Genes Dev.
, vol.17
, pp. 313-321
-
-
Koubova, J.1
Guarente, L.2
-
36
-
-
0034705129
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
Landry, J., A. Sutton, S. T. Tafrov, R. C. Heller, J. Stebbins, L. Pillus, R. Sternglanz, S. Imai, C. M. Armstrong, M. Kaeberlein, and L. Guarente. 2000. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Proc. Natl. Acad. Sci. USA 97:5807-5811.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5807-5811
-
-
Landry, J.1
Sutton, A.2
Tafrov, S.T.3
Heller, R.C.4
Stebbins, J.5
Pillus, L.6
Sternglanz, R.7
Imai, S.8
Armstrong, C.M.9
Kaeberlein, M.10
Guarente, L.11
-
37
-
-
0037093346
-
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
-
Langley, E., M. Pearson, M. Faretta, U. M. Bauer, R. A. Frye, S. Minucci, P. G. Pelicci, and T. Kouzarides. 2002. Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. EMBO J. 21:2383-2396.
-
(2002)
EMBO J.
, vol.21
, pp. 2383-2396
-
-
Langley, E.1
Pearson, M.2
Faretta, M.3
Bauer, U.M.4
Frye, R.A.5
Minucci, S.6
Pelicci, P.G.7
Kouzarides, T.8
-
38
-
-
0033565609
-
Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths
-
Lee, S. E., F. Paques, J. Sylvan, and J. E. Haber. 1999. Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths. Curr. Biol. 9:767-770.
-
(1999)
Curr. Biol.
, vol.9
, pp. 767-770
-
-
Lee, S.E.1
Paques, F.2
Sylvan, J.3
Haber, J.E.4
-
39
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by caloric restriction in Saccharomyces cerevisiae
-
Lin, S.-J., P.-A. Defossez, and L. Guarente. 2000. Requirement of NAD and SIR2 for life-span extension by caloric restriction in Saccharomyces cerevisiae. Science 289:2126-2128.
-
(2000)
Science
, vol.289
, pp. 2126-2128
-
-
Lin, S.-J.1
Defossez, P.-A.2
Guarente, L.3
-
40
-
-
0037130175
-
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
-
Lin, S. J., M. Kaeberlein, A. A. Andalis, L. A. Sturtz, P. A. Defossez, V. C. Culotta, G. R. Fink, and L. Guarente. 2002. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 418:344-348.
-
(2002)
Nature
, vol.418
, pp. 344-348
-
-
Lin, S.J.1
Kaeberlein, M.2
Andalis, A.A.3
Sturtz, L.A.4
Defossez, P.A.5
Culotta, V.C.6
Fink, G.R.7
Guarente, L.8
-
41
-
-
0035913911
-
Negative control of p53 by Sir2α promotes cell survival under stress
-
Luo, J., A. Y. Nikolaev, S. Imai, D. Chen, F. Su, A. Shiloh, L. Guarente, and W. Gu. 2001. Negative control of p53 by Sir2α promotes cell survival under stress. Cell 107:137-148.
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
42
-
-
0033612287
-
Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
-
Martin, S. G., T. Laroche, N. Suka, M. Grunstein, and S. M. Gasser. 1999. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97:621-633.
-
(1999)
Cell
, vol.97
, pp. 621-633
-
-
Martin, S.G.1
Laroche, T.2
Suka, N.3
Grunstein, M.4
Gasser, S.M.5
-
43
-
-
0033539095
-
DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p
-
McAinsh, A. D., S. Scott-Drew, J. A. Murray, and S. P. Jackson. 1999. DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p. Curr. Biol. 9:963-966.
-
(1999)
Curr. Biol.
, vol.9
, pp. 963-966
-
-
McAinsh, A.D.1
Scott-Drew, S.2
Murray, J.A.3
Jackson, S.P.4
-
44
-
-
0037370393
-
Rfm1, a novel tethering factor required to recruit the Hst1 histone deacetylase for repression of middle sporulation genes
-
McCord, R., M. Pierce, J. Xie, S. Wonkatal, C. Mickel, and A. K. Vershon. 2003. Rfm1, a novel tethering factor required to recruit the Hst1 histone deacetylase for repression of middle sporulation genes. Mol. Cell. Biol. 23:2009-2016.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 2009-2016
-
-
McCord, R.1
Pierce, M.2
Xie, J.3
Wonkatal, S.4
Mickel, C.5
Vershon, A.K.6
-
45
-
-
0033612189
-
MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks
-
Mills, K. D., D. A. Sinclair, and L. Guarente. 1999. MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks. Cell 97:609-620.
-
(1999)
Cell
, vol.97
, pp. 609-620
-
-
Mills, K.D.1
Sinclair, D.A.2
Guarente, L.3
-
46
-
-
0034791301
-
Common themes in mechanisms of gene silencing
-
Moazed, D. 2001. Common themes in mechanisms of gene silencing. Mol. Cell 8:489-498.
-
(2001)
Mol. Cell
, vol.8
, pp. 489-498
-
-
Moazed, D.1
-
47
-
-
0030951007
-
Silent information regulator protein complexes in Saccharomyces cerevisiae: A SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3
-
Moazed, D., A. Kistler, A. Axelrod, J. Rine, and A. D. Johnson. 1997. Silent information regulator protein complexes in Saccharomyces cerevisiae: a SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3. Proc. Natl. Acad. Sci. USA 94:2186-2191.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2186-2191
-
-
Moazed, D.1
Kistler, A.2
Axelrod, A.3
Rine, J.4
Johnson, A.D.5
-
49
-
-
0037108799
-
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
-
Onyango, P., I. Celic, J. M. McCaffery, J. D. Boeke, and A. P. Feinberg. 2002. SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc. Natl. Acad. Sci. USA 99:13653-13658.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13653-13658
-
-
Onyango, P.1
Celic, I.2
McCaffery, J.M.3
Boeke, J.D.4
Feinberg, A.P.5
-
50
-
-
0035863153
-
A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast
-
Perrod, S., M. M. Cockell, T. Laroche, H. Renauld, A. L. Ducrest, C. Bonnard, and S. M. Gasser. 2001. A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast. EMBO J. 20:197-209.
-
(2001)
EMBO J.
, vol.20
, pp. 197-209
-
-
Perrod, S.1
Cockell, M.M.2
Laroche, T.3
Renauld, H.4
Ducrest, A.L.5
Bonnard, C.6
Gasser, S.M.7
-
51
-
-
0001509184
-
Nicotinamide deamidase from mammalian liver
-
Petrack, B., P. Greengard, A. Craston, and F. Sheppy. 1965. Nicotinamide deamidase from mammalian liver. J. Biol. Chem. 240:1725-1730.
-
(1965)
J. Biol. Chem.
, vol.240
, pp. 1725-1730
-
-
Petrack, B.1
Greengard, P.2
Craston, A.3
Sheppy, F.4
-
52
-
-
0000951067
-
Conversion of a cosubstrate to an inhibitor: Phosphorylation mutants of nicotinic acid phosphoribosyltransferase
-
Rajavel, M., D. Lalo, J. W. Gross, and C. Grubmeyer. 1998. Conversion of a cosubstrate to an inhibitor: phosphorylation mutants of nicotinic acid phosphoribosyltransferase. Biochemistry 37:4181-4188.
-
(1998)
Biochemistry
, vol.37
, pp. 4181-4188
-
-
Rajavel, M.1
Lalo, D.2
Gross, J.W.3
Grubmeyer, C.4
-
53
-
-
0036324497
-
Ordered nucleation and spreading of silenced chromatin in Saccharomyces cerevisiae
-
Rusche, L. N., A. L. Kirchmaier, and J. Rine. 2002. Ordered nucleation and spreading of silenced chromatin in Saccharomyces cerevisiae. Mol. Biol. Cell. 13:2207-2222.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 2207-2222
-
-
Rusche, L.N.1
Kirchmaier, A.L.2
Rine, J.3
-
55
-
-
0037119973
-
RPD3 is required for the inactivation of yeast ribosomal DNA genes in stationary phase
-
Sandmeier, J. J., S. French, Y. Osheim, W. L. Cheung, C. M. Gallo, A. L. Beyer, and J. S. Smith. 2002. RPD3 is required for the inactivation of yeast ribosomal DNA genes in stationary phase. EMBO J. 21:4959-4968.
-
(2002)
EMBO J.
, vol.21
, pp. 4959-4968
-
-
Sandmeier, J.J.1
French, S.2
Osheim, Y.3
Cheung, W.L.4
Gallo, C.M.5
Beyer, A.L.6
Smith, J.S.7
-
56
-
-
0037135972
-
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
-
Schwer, B., B. J. North, R. A. Frye, M. Ott, and E. Verdin. 2002. The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. J. Cell Biol. 158:647-657.
-
(2002)
J. Cell Biol.
, vol.158
, pp. 647-657
-
-
Schwer, B.1
North, B.J.2
Frye, R.A.3
Ott, M.4
Verdin, E.5
-
57
-
-
0032534506
-
Heat stress-induced life span extension in yeast
-
Shama, S., C. Y. Lai, J. M. Antoniazzi, J. C. Jiang, and S. M. Jazwinski. 1998. Heat stress-induced life span extension in yeast. Exp. Cell Res. 245:379-388.
-
(1998)
Exp. Cell Res.
, vol.245
, pp. 379-388
-
-
Shama, S.1
Lai, C.Y.2
Antoniazzi, J.M.3
Jiang, J.C.4
Jazwinski, S.M.5
-
58
-
-
0033574594
-
Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex
-
Shou, W., J. H. Seol, A. Shevchenko, C. Baskerville, D. Moazed, Z. W. Chen, J. Jang, H. Charbonneau, and R. J. Deshaies. 1999. Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex. Cell 97:233-244.
-
(1999)
Cell
, vol.97
, pp. 233-244
-
-
Shou, W.1
Seol, J.H.2
Shevchenko, A.3
Baskerville, C.4
Moazed, D.5
Chen, Z.W.6
Jang, J.7
Charbonneau, H.8
Deshaies, R.J.9
-
59
-
-
0030820491
-
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants
-
Sinclair, D. A., K. Mills, and L. Guarente. 1997. Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants. Science 277:1313-1316.
-
(1997)
Science
, vol.277
, pp. 1313-1316
-
-
Sinclair, D.A.1
Mills, K.2
Guarente, L.3
-
61
-
-
0031056907
-
An unusual form of transcriptional silencing in yeast ribosomal DNA
-
Smith, J. S., and J. D. Boeke. 1997. An unusual form of transcriptional silencing in yeast ribosomal DNA. Genes Dev. 11:241-254.
-
(1997)
Genes Dev.
, vol.11
, pp. 241-254
-
-
Smith, J.S.1
Boeke, J.D.2
-
62
-
-
12944283150
-
+ -dependent protein deacetylase activity in the Sir2 protein family
-
+ -dependent protein deacetylase activity in the Sir2 protein family. Proc. Natl. Acad. Sci. USA 97:6658-6663.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6658-6663
-
-
Smith, J.S.1
Brachmann, C.B.2
Celic, I.3
Kenna, M.A.4
Muhammad, S.5
Starai, V.J.6
Avalos, J.L.7
Escalante-Semerena, J.C.8
Grubmeyer, C.9
Wolberger, C.10
Boeke, J.D.11
-
63
-
-
0036467928
-
Concurrent quantification of quinolinic, picolinic, and nicotinic acids using electron-capture negative-ion gas chromatography-mass spectrometry
-
Smythe, G. A., O. Braga, B. J. Brew, R. S. Grant, G. J. Guillemin, S. J. Kerr, and D. W. Walker. 2002. Concurrent quantification of quinolinic, picolinic, and nicotinic acids using electron-capture negative-ion gas chromatography-mass spectrometry. Anal. Biochem. 301:21-26.
-
(2002)
Anal. Biochem.
, vol.301
, pp. 21-26
-
-
Smythe, G.A.1
Braga, O.2
Brew, B.J.3
Grant, R.S.4
Guillemin, G.J.5
Kerr, S.J.6
Walker, D.W.7
-
64
-
-
0347457075
-
Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine
-
Starai, V. J., I. Celic, R. N. Cole, J. D. Boeke, and J. C. Escalante-Semerena. 2002. Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine. Science 298:2390-2392.
-
(2002)
Science
, vol.298
, pp. 2390-2392
-
-
Starai, V.J.1
Celic, I.2
Cole, R.N.3
Boeke, J.D.4
Escalante-Semerena, J.C.5
-
65
-
-
0031027431
-
SIR2 and SIR4 interactions differ in core and extended telomerie heterochromatin in yeast
-
Strahl-Bolsinger, S., A. Hecht, K. Luo, and M. Grunstein. 1997. SIR2 and SIR4 interactions differ in core and extended telomerie heterochromatin in yeast. Genes Dev. 11:83-93.
-
(1997)
Genes Dev.
, vol.11
, pp. 83-93
-
-
Strahl-Bolsinger, S.1
Hecht, A.2
Luo, K.3
Grunstein, M.4
-
66
-
-
0033574603
-
Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity
-
Straight, A. F., W. Shou, G. J. Dowd, C. W. Turck, R. J. Deshaies, A. D. Johnson, and D. Moazed. 1999. Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity. Cell 97:245-256.
-
(1999)
Cell
, vol.97
, pp. 245-256
-
-
Straight, A.F.1
Shou, W.2
Dowd, G.J.3
Turck, C.W.4
Deshaies, R.J.5
Johnson, A.D.6
Moazed, D.7
-
67
-
-
0025881033
-
Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: Isolation of viable mutants affecting both silencing and telomere length
-
Sussel, L., and D. Shore. 1991. Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: isolation of viable mutants affecting both silencing and telomere length. Proc. Natl. Acad. Sci. USA 88:7749-7753.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7749-7753
-
-
Sussel, L.1
Shore, D.2
-
68
-
-
0033598942
-
An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing
-
Tanny, J. C., G. J. Dowd, J. Huang, H. Hilz, and D. Moazed. 1999. An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing. Cell 99:735-745.
-
(1999)
Cell
, vol.99
, pp. 735-745
-
-
Tanny, J.C.1
Dowd, G.J.2
Huang, J.3
Hilz, H.4
Moazed, D.5
-
69
-
-
0035895275
-
Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product
-
Tanny, J. C., and D. Moazed. 2001. Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: evidence for acetyl transfer from substrate to an NAD breakdown product. Proc. Natl. Acad. Sci. USA 98:415-420.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 415-420
-
-
Tanny, J.C.1
Moazed, D.2
-
70
-
-
0035913903
-
SIRT1 functions as an NAD-dependent p53 deacetylase
-
SIRT1 functions as an NAD-dependent p53 deacetylase. Cell 107:149-159.
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vazirii, H.1
Dessain, S.K.2
Eaton, E.N.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
71
-
-
0036733355
-
The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
-
Virag, L., and C. Szabo. 2002. The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol. Rev. 54:375-429.
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 375-429
-
-
Virag, L.1
Szabo, C.2
-
72
-
-
0018729615
-
Nicotinamide deamidase released by neuroblastoma cell cultures
-
Wintzerith, M., A. Dierich, and P. Mandel. 1979. Nicotinamide deamidase released by neuroblastoma cell cultures. J. Neurochem. 33:677-685.
-
(1979)
J. Neurochem.
, vol.33
, pp. 677-685
-
-
Wintzerith, M.1
Dierich, A.2
Mandel, P.3
-
73
-
-
0033570901
-
Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae
-
Xie, J., M. Pierce, V. Gailus-Durner, M. Wagner, E. Winter, and A. K. Vershon. 1999. Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae. EMBO J. 18:6448-6454.
-
(1999)
EMBO J.
, vol.18
, pp. 6448-6454
-
-
Xie, J.1
Pierce, M.2
Gailus-Durner, V.3
Wagner, M.4
Winter, E.5
Vershon, A.K.6
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