Orphan nuclear receptor-mediated xenobiotic regulation in drug metabolism

Drug Discovery Today

Volumn 9, Issue 10, 2004, Pages 442-449

  Xie, Wen ^a   Uppal, Hirdesh ^a   Saini, Simrat P S ^a   Mu, Ying ^a   Little, Joanna M ^b   Radominska Pandya, Anna ^b   Zemaitis, Michael A ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Drug Discovery; Drug metabolizing enzymes; Gene regulation; Genetics; Molecular Medicine; Orphan nuclear receptor; Pharmaceutical Science; Techniques Methods; Transportershuman diseases

Indexed keywords

BILE ACID; CELL NUCLEUS RECEPTOR; CONSTITUTIVE ANDROSTANE RECEPTOR; FARNESOID X RECEPTOR; PREGNANE X RECEPTOR; RETINOID X RECEPTOR; RIFAMPICIN; VITAMIN D RECEPTOR;

BIOTRANSFORMATION; CEREBROTENDINOUS XANTHOMATOSIS; CHOLESTASIS; CHOLESTATIC HEPATITIS; DETOXIFICATION; DRUG METABOLISM; GENE ACTIVITY; GENE CONTROL; GENE EXPRESSION; HOMEOSTASIS; HUMAN; HYPERICUM PERFORATUM; JAUNDICE; NONHUMAN; PROTEIN EXPRESSION; PRURITUS; REVIEW; XENOBIOTIC METABOLISM;

ANIMALS; BILE ACIDS AND SALTS; BILIRUBIN; CARRIER PROTEINS; ENZYMES; GENE EXPRESSION REGULATION; HUMANS; LIPID METABOLISM; METABOLIC DETOXICATION, DRUG; MICE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; RECEPTORS, VIRUS; SPECIES SPECIFICITY; XENOBIOTICS;

EID: 1942453212     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(04)03061-2     Document Type: Review

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