Orphan Receptor Promiscuity in the Induction of Cytochromes P450 by Xenobiotics

Journal of Biological Chemistry

Volumn 276, Issue 16, 2001, Pages 12822-12826

  Smirlis, Despina ^a   Muangmoonchai, Roongsiri ^a,c   Edwards, Mina ^a   Phillips, Ian R ^b   Shephard, Elizabeth A ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c CHIANG MAI UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CHEMICAL ACTIVATION; CHEMICAL BONDS; COMPLEXATION; DNA; GENES; HORMONES;

CYTOCHROMES;

CYTOLOGY;

ANDROSTANE RECEPTOR; BARBITURIC ACID DERIVATIVE; CELL NUCLEUS RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 2B1; CYTOCHROME P450 3A1; ORPHAN RECEPTOR; PHENOBARBITAL; PREGNANE X RECEPTOR; STEROID; UNCLASSIFIED DRUG; XENOBIOTIC AGENT; CELL RECEPTOR; CHLORAMPHENICOL ACETYLTRANSFERASE; CONSTITUTIVE ANDROSTANE RECEPTOR; CYP3A PROTEIN, HUMAN; HYBRID PROTEIN; MIXED FUNCTION OXIDASE; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; STEROID RECEPTOR; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA BINDING; DNA RESPONSIVE ELEMENT; ENHANCER REGION; ENZYME INDUCTION; GENE EXPRESSION; GENETIC TRANSFECTION; IN VIVO STUDY; LIGAND BINDING; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; RECEPTOR BINDING; RECEPTOR INTRINSIC ACTIVITY; TRANSACTIVATION; ANIMAL; BIOLISTIC TRANSFORMATION; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DIMERIZATION; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; MOUSE; PHYSIOLOGY; SALAMANDER;

ANIMALIA;

ANIMALS; BIOLISTICS; CELLS, CULTURED; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 ENZYME SYSTEM; DIMERIZATION; ENZYME INDUCTION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEPATOCYTES; MICE; MIXED FUNCTION OXYGENASES; PROMOTER REGIONS (GENETICS); RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, RETINOIC ACID; RECEPTORS, STEROID; RECOMBINANT FUSION PROTEINS; RETINOID X RECEPTORS; SALAMANDRIDAE; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION; XENOBIOTICS;

EID: 0035918186     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M005930200     Document Type: Article

References (29)

1. Guengerich, F. P. (ed) (1987) Mammalian Cytochromes P450, Vols. I and II, CRC Press Inc., Boca Raton, FL
2. Gonzalez, F. J. (1989) Pharmacol Rev. 40, 243-288
3. Waxman, D. J. (1999) Arch. Biochem. Biophys. 369, 11-23
4. Honkakoski, P., and Negishi, M. (2000) Biochem. J. 347, 321-337
5. Phillips, I. R., Shephard, E. A., Rabin, B. R., Ashworth, A., Bayney, R. M., and Pike, S. F. (1985) in Drug Metabolism, Molecular Approaches and Pharmacological Implications (Siest, G., ed) pp. 93-102, Pergamon Press, Oxford
6. Heuman, D. M., Gallagher, E. J., Barwick, J. L., Elshourbagy, N. A., and Guzelian, P. S. (1982) Mol. Pharmacol. 21, 753-760
7. Choi, H. S., Chung, M., Tzameli, I., Simha, D., Lee, Y. K., Seol, W., and Moore, D. D. (1997) J. Biol. Chem. 272, 23565-23571
8. Trottier, E., Belzil, A., Stoltz, C., and Anderson, A. (1995) Gene 158, 263-268
9. Honkakoski, P., Zelko, I., Sueyoshi, T., and Negishi, M. (1998) Mol. Cell. Biol. 18, 5652-5658
10. Kliewer, S. A., Moore, J. T., Wade, L., Staudinger, J. L., Watson, M. A., Jones, S. A., McKee, D. D., Oliver, B. B., Willson, T. M., Zetterstrom, R. H., Perlmann, T., and Lehmann, J. M. (1998) Cell 92, 73-82
11. Bertilsson, G., Heidrich, J., Svensson, K., Asman, M., Jendeberg, L., Sydow-Backman, M., Ohlsson, R., Postlind, H., Blomquist, P., and Berkenstam, A. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 12208-122013
12. Blumberg, B., Sabbagh, W., Jr., Juguilon, H., Bolado, J., Jr., van Meter, C. M., Ong, E. S., and Evans, R. M. (1998) Genes Dev. 12, 3195-3205
13. Quattrochi, L. C., Yockey, C. B., Barwick, J. L., and Guzelian, P. S. (1998) Arch. Biochem. Biophys. 349, 251-260
14. Dignam, J. D., Lebovitz, R. M., and Roeder, R. G. (1983) Nucleic Acids Res. 11, 1475-1489
15. Dell, H., Wong, S. C., Phillips, I. R., and Shephard, E. A. (1998) in Methods in Molecular Biology (Phillips, I. R., and Shephard, E. A., eds) Vol. 107, pp. 381-394, Humana Press, Totowa, NJ
16. Liu, S., Park, Y., Rivera-Rivera, I., Li, H., and Kemper, B. (1998) DNA Cell Biol. 17, 461-470
17. Muangmoonchai, R., Smirlis, D., Wong, S.-C., Edwards, M., Phillips, I. R., and Shephard, E. A. (2001) Biochem. J. 355, 71-78
18. Tzameli, I., Pissios, P., Schuetz, E. G., and Moore, D. D. (2000) Mol. Cell. Biol. 20, 2951-2958
19. Waxman, D. J., and Azaroff, L. (1992) Biochem. J. 281, 577-592
20. Rastinejad, F. (1998) in Molecular Biology of Steroid and Nuclear Hormone Receptors (Freedman, L., ed) pp. 105-132, Birkhäuser, Boston
21. Sueyoshi, T., Kawamoto, T., Zelko, I., Honkakoski, P., and Negishi, M. (1999) J. Biol. Chem. 274, 6043-6046
22. Forman, B. M., Tzameli, I., Choi, H. S., Chen, J., Simha, D., Seol, W., Evans, R. M., and Moore, D. D. (1998) Nature 395, 612-615
23. Glass, C. K. (1994) Endocr. Rev. 15, 391-407
24. Moore, L. B., Parks, D. J., Jones, S. A., Bledsoe, R. K., Consler, T. G., Stimmel, J. B., Goodwin, B., Liddle, C., Blanchard, S. G., Willson, T. M., Collins, J. L., and Kliewer, S. A. (2000) J. Biol. Chem. 275, 15122-15127
25. Baes, M., Gulick, T., Choi, H. S., Martinoli, M. G., Simha, D., and Moore, D. D. (1994) Mol. Cell. Biol. 14, 1544-1551
26. Onate, S. A., Tsai, S. Y., Tsai, M. J., and O'Malley, B. W. (1995) Science 270, 1354-1357
27. Kassam, A., Winrow, C. J., Fernandez-Rachubinski, F., Capone, J. P., and Rachubinski, R. A. (2000) J. Biol. Chem. 275, 4345-4350
28. Frueh, F. W., Zanger, U. M., and Meyer, U. A. (1997) Mol. Pharmacol. 51, 363-369
29. Wei, P., Zhang, J., Egan-Hafley, M., Liang, S., and Moore, D. D. (2000) Nature 407, 920-923