Vitamin K2 Regulation of Bone Homeostasis Is Mediated by the Steroid and Xenobiotic Receptor SXR

Journal of Biological Chemistry

Volumn 278, Issue 45, 2003, Pages 43919-43927

  Tabb, Michelle M ^a   Sun, Aixu ^a   Zhou, Changcheng ^a   Grün, Felix ^a   Errandi, Jody ^a   Romero, Kimberly ^a   Pham, Hang ^a   Inoue, Satoshi ^b   Mallick, Shyamali ^c   Lin, Min ^c   Forman, Barry M ^c   Blumberg, Bruce ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

^c CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMARKERS; BLOOD; BONE; NUTRITION; RNA; SENSORS;

BLOOD CLOTTING;

VITAMINS;

16ALPHA CYANOPREGNENOLONE; ALKALINE PHOSPHATASE; BIOLOGICAL MARKER; CALCITRIOL; CELL NUCLEUS RECEPTOR; CYCLOHEXIMIDE; CYTOCHROME P450 3A4; DEXAMETHASONE; FARNOQUINONE; HYPERFORIN; LIGAND; MESSENGER RNA; OSTEOCALCIN; OSTEOPONTIN; OSTEOPROTEGERIN; PREGNANE X RECEPTOR; RIFAMPICIN; SCLEROPROTEIN; STEROID AND XENOBIOTIC RECEPTOR; UNCLASSIFIED DRUG; XENOBIOTIC AGENT; BICYCLO COMPOUND; CELL RECEPTOR; CYP3A PROTEIN, HUMAN; CYP3A4 PROTEIN, HUMAN; CYTOCHROME P450; DRUG DERIVATIVE; GLYCOPROTEIN; PHLOROGLUCINOL; RECOMBINANT PROTEIN; SIALOGLYCOPROTEIN; SPP1 PROTEIN, HUMAN; SPP1 PROTEIN, MOUSE; STEROID RECEPTOR; SXR RECEPTOR; TERPENE; TNFRSF11B PROTEIN, HUMAN; TNFRSF11B PROTEIN, MOUSE; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE; BONE DENSITY; BONE MATRIX; CALVARIA; CARBOXYLATION; CELL ISOLATION; CONTROLLED STUDY; DRUG MECHANISM; GENE TARGETING; HOMEOSTASIS; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; LIGAND BINDING; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; OSSIFICATION; OSTEOBLAST; OSTEOCYTE; OSTEOPOROSIS; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENSOR; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UPREGULATION; VITAMIN SUPPLEMENTATION; WILD TYPE; XENOBIOTIC METABOLISM; ANIMAL; CELL CULTURE; CELL STRAIN COS1; CHEMISTRY; DRUG EFFECT; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; HELA CELL; METABOLISM; MOUSE MUTANT; OSTEOSARCOMA; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALIA; MURINAE;

ALKALINE PHOSPHATASE; ANIMALS; BICYCLO COMPOUNDS; BIOLOGICAL MARKERS; BONE AND BONES; BONE DENSITY; COS CELLS; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION; GLYCOPROTEINS; HELA CELLS; HOMEOSTASIS; HUMANS; MICE; MICE, KNOCKOUT; OSTEOBLASTS; OSTEOCALCIN; OSTEOPONTIN; OSTEOPROTEGERIN; OSTEOSARCOMA; PHLOROGLUCINOL; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; RECEPTORS, TUMOR NECROSIS FACTOR; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIFAMPIN; RNA, MESSENGER; SIALOGLYCOPROTEINS; TERPENES; TRANSFECTION; TUMOR CELLS, CULTURED; VITAMIN K 2;

EID: 0242498469     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M303136200     Document Type: Article

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