A Novel Constitutive Androstane Receptor-Mediated and CYP3A-Independent Pathway of Bile Acid Detoxification

Molecular Pharmacology

Volumn 65, Issue 2, 2004, Pages 292-300

  Saini, Simrat P S ^a   Sonoda, Junichiro ^b   Xu, Li ^a   Toma, David ^a   Uppal, Hirdesh ^a   Mu, Ying ^a   Ren, Songrong ^a   Moore, David D ^c   Evans, Ronald M ^b   Xie, Wen ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE; BILE ACID; CELL RECEPTOR; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 3A; ERYTHROMYCIN N DEMETHYLASE; ERYTHROMYCIN N-DEMETHYLASE; LITHOCHOLIC ACID; MULTIENZYME COMPLEX; N DEMETHYLASE; PAPS SYNTHETASE; PHENOL SULPHOTRANSFERASE; RECEPTOR PROTEIN; SULFATE ADENYLYLTRANSFERASE; SULFOTRANSFERASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ANIMAL; ANIMAL TISSUE; ARTICLE; BILE ACID METABOLISM; CHOLESTASIS; COLON CANCER; COMPARATIVE STUDY; CONTROLLED STUDY; DETOXIFICATION; DRUG DETOXIFICATION; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENE EXPRESSION; GENETICS; KNOCKOUT GENE; KNOCKOUT MOUSE; LIVER; LIVER INJURY; LIVER TOXICITY; MALE; METABOLISM; MOUSE; NONHUMAN; NUTRITIONAL DEFICIENCY; PATHOLOGY; PHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SULFATION; TRANSGENIC MOUSE;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; ARYLSULFOTRANSFERASE; BILE ACIDS AND SALTS; CYTOCHROME P-450 CYP3A; FEMALE; LITHOCHOLIC ACID; LIVER; MALE; METABOLIC DETOXICATION, DRUG; MICE; MICE, TRANSGENIC; MULTIENZYME COMPLEXES; OXIDOREDUCTASES, N-DEMETHYLATING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; SULFATE ADENYLYLTRANSFERASE; SULFOTRANSFERASES; TRANSCRIPTION FACTORS;

EID: 9144231188     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.65.2.292     Document Type: Article

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