Cellular processing of platinum anticancer drugs

Nature Reviews Drug Discovery

Volumn 4, Issue 4, 2005, Pages 307-320

  Wang, Dong ^a   Lippard, Stephen J ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABELSON KINASE; AMMINEDICHLORO(2 METHYLPYRIDINE)PLATINUM; ANTINEOPLASTIC AGENT; CARBOPLATIN; CELL CYCLE PROTEIN; CISPLATIN; DNA; FLUOROURACIL; HIGH MOBILITY GROUP B1 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; NEW DRUG; OXALIPLATIN; PACLITAXEL; PLATINUM DERIVATIVE; PROTEIN KINASE B; PROTEIN P53; SATRAPLATIN; STRESS ACTIVATED PROTEIN KINASE; TRICHOSTATIN A; VORINOSTAT; PLATINUM COMPLEX;

CANCER CHEMOTHERAPY; CELL CYCLE; CELL DEATH; CELL FUNCTION; CHEMOTHERAPY INDUCED EMESIS; CYTOTOXICITY; DNA ADDUCT; DNA DAMAGE; DNA REPAIR; DRUG DESIGN; DRUG DNA INTERACTION; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; DRUG UPTAKE; HUMAN; MALIGNANT NEOPLASTIC DISEASE; NEPHROTOXICITY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; REVIEW; ANIMAL; APOPTOSIS; CELL CULTURE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL SURVIVAL; DNA DAMAGE; DNA REPAIR; HUMANS; MOLECULAR STRUCTURE; ORGANOPLATINUM COMPOUNDS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 18244379333     PISSN: 14741776     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrd1691     Document Type: Review

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