메뉴 건너뛰기




Volumn 7, Issue 4, 2000, Pages 393-401

DNA repair is activated in early stages of p53-induced apoptosis

Author keywords

Apoptosis; DNA repair; p53

Indexed keywords

PROTEIN P21; PROTEIN P53;

EID: 0034128509     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400663     Document Type: Article
Times cited : (55)

References (57)
  • 1
    • 0031691804 scopus 로고    scopus 로고
    • Histopathological evaluation of apoptosis in cancer
    • Soini Y, Paakko P and Lehto V-P (1998) Histopathological evaluation of apoptosis in cancer. Am. J. Pathol. 153: 1041-1053
    • (1998) Am. J. Pathol. , vol.153 , pp. 1041-1053
    • Soini, Y.1    Paakko, P.2    Lehto, V.-P.3
  • 3
    • 0030046508 scopus 로고    scopus 로고
    • Life, death, and the pursuit of apoptosis
    • White E (1996) Life, death, and the pursuit of apoptosis. Genes Dev. 10: 1-15
    • (1996) Genes Dev. , vol.10 , pp. 1-15
    • White, E.1
  • 4
    • 0031051042 scopus 로고    scopus 로고
    • P53; from inductive signal to cellular effect
    • Hansen R and Oren M (1997) p53; from inductive signal to cellular effect. Curr. Opin. Gene. Dev. 7: 46-51
    • (1997) Curr. Opin. Gene. Dev. , vol.7 , pp. 46-51
    • Hansen, R.1    Oren, M.2
  • 5
    • 0029802591 scopus 로고    scopus 로고
    • P53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
    • Chen X, Ko LJ, Jayaraman L and Prives C (1996) p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev. 10: 2438-2451
    • (1996) Genes Dev. , vol.10 , pp. 2438-2451
    • Chen, X.1    Ko, L.J.2    Jayaraman, L.3    Prives, C.4
  • 7
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt MS, Bennett WP, Hollstein M and Harris CC (1994) Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res. 54: 4855-4878
    • (1994) Cancer Res. , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 8
    • 0029972806 scopus 로고    scopus 로고
    • P53: Puzzle and paradigm
    • Ko LJ and Prives C (1996) p53: puzzle and paradigm. Genes Dev. 10: 1054-1072
    • (1996) Genes Dev. , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 10
    • 0027496935 scopus 로고
    • The p21 cdk-interacting protein Cip 1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper JW, Adami GR, Wei N, Keyomarsi K and Elledge SJ (1993)The p21 cdk-interacting protein Cip 1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75: 805-816
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 11
    • 0030119061 scopus 로고    scopus 로고
    • The two faces of tumor suppressor p53
    • Smith ML and Fornace Jr AJ (1996) The two faces of tumor suppressor p53. Am. J. Pathol. 148: 1019-1022
    • (1996) Am. J. Pathol. , vol.148 , pp. 1019-1022
    • Smith, M.L.1    Fornace A.J., Jr.2
  • 12
    • 0029319659 scopus 로고
    • Stopped for repairs
    • Sanchez Y and Elledge SJ (1995) Stopped for repairs. BioEssays 17: 545-548
    • (1995) BioEssays , vol.17 , pp. 545-548
    • Sanchez, Y.1    Elledge, S.J.2
  • 14
    • 0001655748 scopus 로고
    • Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3
    • Wang XW, Forrester K, Yeh H, Feitelson MA, Gu J-R and Harris CC (1994) Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3. Proc. Natl. Acad. Sci. USA 91: 2230-2234
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2230-2234
    • Wang, X.W.1    Forrester, K.2    Yeh, H.3    Feitelson, Ma.4    Gu, J.-R.5    Harris, C.C.6
  • 16
    • 0029055808 scopus 로고
    • Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus
    • Jayaraman L and Prives C (1995) Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus. Cell 81: 1021-1029
    • (1995) Cell , vol.81 , pp. 1021-1029
    • Jayaraman, L.1    Prives, C.2
  • 17
    • 0029013273 scopus 로고
    • P53 and its 14kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches
    • Lee S, Elenbass B, Levine A and Griffith J (1995) p53 and its 14kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches. Cell 81: 1013-1020
    • (1995) Cell , vol.81 , pp. 1013-1020
    • Lee, S.1    Elenbass, B.2    Levine, A.3    Griffith, J.4
  • 19
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams JM and Cory S (1998) The Bcl-2 protein family: arbiters of cell survival. Science 281: 1322-1326
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 20
    • 0028958705 scopus 로고
    • Growth factor modulation of p53-mediated growth arrest versus apoptosis
    • Canman CE, Gilmer TM, Courts SB and Kastan MB (1995) Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes Dev. 9: 600-611
    • (1995) Genes Dev. , vol.9 , pp. 600-611
    • Canman, C.E.1    Gilmer, T.M.2    Courts, S.B.3    Kastan, M.B.4
  • 21
    • 0030802364 scopus 로고    scopus 로고
    • A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis
    • Israeli D, Tessler E, Haupt Y, Elkeles A, Wilder S, Amson R, Telerman A and Oren M (1997) A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis. EMBO J. 16: 4384-4392
    • (1997) EMBO J. , vol.16 , pp. 4384-4392
    • Israeli, D.1    Tessler, E.2    Haupt, Y.3    Elkeles, A.4    Wilder, S.5    Amson, R.6    Telerman, A.7    Oren, M.8
  • 25
    • 0022602887 scopus 로고
    • Properties of mouse mammary epithelial cell lines characterized by in vivo transplantation and in vitro immunocytochemical methods
    • Medina D, Oborn CJ, Kittrell FS and Ullrich RL (1986) Properties of mouse mammary epithelial cell lines characterized by in vivo transplantation and in vitro immunocytochemical methods. J. Natl. Cancer Inst. 76: 1143-1151
    • (1986) J. Natl. Cancer Inst. , vol.76 , pp. 1143-1151
    • Medina, D.1    Oborn, C.J.2    Kittrell, F.S.3    Ullrich, R.L.4
  • 26
    • 0030950749 scopus 로고    scopus 로고
    • Differential induction of growth arrest inducible genes by selenium compounds
    • Kaeck M, Lu J, Strange R, Ip C, Ganther HE and Thompson HJ (1997) Differential induction of growth arrest inducible genes by selenium compounds. Biochem. Pharm. 53: 921-926
    • (1997) Biochem. Pharm. , vol.53 , pp. 921-926
    • Kaeck, M.1    Lu, J.2    Strange, R.3    Ip, C.4    Ganther, H.E.5    Thompson, H.J.6
  • 27
    • 0025111068 scopus 로고
    • Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53
    • Michalovitz D, Halevy O and Oren M (1990) Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53. Cell 62: 671-680
    • (1990) Cell , vol.62 , pp. 671-680
    • Michalovitz, D.1    Halevy, O.2    Oren, M.3
  • 28
    • 0030941458 scopus 로고    scopus 로고
    • P53, the cellular gatekeeper for growth and division
    • Levine AJ (1997) p53, the cellular gatekeeper for growth and division. Cell 88: 323-331
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 29
    • 0023878893 scopus 로고
    • Complementation of the Xeroderma Pigmentosum DNA repair defect in cell-free extracts
    • Wood RD, Robins P and Lindahl T (1988) Complementation of the Xeroderma Pigmentosum DNA repair defect in cell-free extracts. Cell 53: 97-106
    • (1988) Cell , vol.53 , pp. 97-106
    • Wood, R.D.1    Robins, P.2    Lindahl, T.3
  • 30
    • 0031801634 scopus 로고    scopus 로고
    • Proteins that specifically recognize cisplatin-damaged DNA: A clue to anticancer activity of cisplatin
    • Zlatanova J, Yaneva J and Leuba SH (1998) Proteins that specifically recognize cisplatin-damaged DNA: a clue to anticancer activity of cisplatin. FASEB J. 12: 791-799
    • (1998) FASEB J. , vol.12 , pp. 791-799
    • Zlatanova, J.1    Yaneva, J.2    Leuba, S.H.3
  • 31
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry NA and Lazebnik Y (1998) Caspases: enemies within. Science 281: 1312-1316
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 32
    • 2642689658 scopus 로고    scopus 로고
    • Proteases to die for
    • Cryns V and Yuan J (1998) Proteases to die for, Genes Dev. 12: 1551-1570
    • (1998) Genes Dev. , vol.12 , pp. 1551-1570
    • Cryns, V.1    Yuan, J.2
  • 33
    • 0032561471 scopus 로고    scopus 로고
    • Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system
    • Ding H-F, McGill G, Rowan S, Schmaltz C, Shimamura A and Fisher DE (1998) Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system. J. Biol. Chem. 273: 28378-28383
    • (1998) J. Biol. Chem. , vol.273 , pp. 28378-28383
    • Ding, H.-F.1    McGill, G.2    Rowan, S.3    Schmaltz, C.4    Shimamura, A.5    Fisher, D.E.6
  • 34
    • 0030696171 scopus 로고    scopus 로고
    • P53 expression overcomes p21/WAF1/CIP1-mediated G1 arrest and induces apoptosis in human cancer cells
    • Kagawa S, Fujiwara T, Hizuta A, Yasuda T, Zhang WW, Roth JA and Tanaka N (1997) p53 expression overcomes p21/WAF1/CIP1-mediated G1 arrest and induces apoptosis in human cancer cells. Oncogene 15: 1903-1909
    • (1997) Oncogene , vol.15 , pp. 1903-1909
    • Kagawa, S.1    Fujiwara, T.2    Hizuta, A.3    Yasuda, T.4    Zhang, W.W.5    Roth, J.A.6    Tanaka, N.7
  • 35
    • 25744452036 scopus 로고
    • Evidence for DNA repair in cycloheximide-induced apoptosis using human and mouse cell lines
    • Geske FJ, Lieberman R, Strange R and Gerschenson LE (1995) Evidence for DNA repair in cycloheximide-induced apoptosis using human and mouse cell lines. FASEB J. 9: A419
    • (1995) FASEB J. , vol.9
    • Geske, F.J.1    Lieberman, R.2    Strange, R.3    Gerschenson, L.E.4
  • 36
    • 0029029741 scopus 로고
    • Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance
    • Ford JM and Hanawalt PC (1995) Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance. Proc. Natl. Acad. Sci. USA 92: 8876-8880
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8876-8880
    • Ford, J.M.1    Hanawalt, P.C.2
  • 37
    • 0030853074 scopus 로고    scopus 로고
    • Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts
    • Ford JM and Hanawalt PC (1997) Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts. J. Biol. Chem. 272: 28073-28080
    • (1997) J. Biol. Chem. , vol.272 , pp. 28073-28080
    • Ford, J.M.1    Hanawalt, P.C.2
  • 38
    • 0033011560 scopus 로고    scopus 로고
    • Prodomains-adaptors-oligomerization: The pursuit of caspase activation in apoptosis
    • Kumar S and Colussi PA (1999) Prodomains-adaptors-oligomerization: the pursuit of caspase activation in apoptosis. Trends Biochem. Sci. 24: 1-4
    • (1999) Trends Biochem. Sci. , vol.24 , pp. 1-4
    • Kumar, S.1    Colussi, P.A.2
  • 39
    • 0008824942 scopus 로고    scopus 로고
    • The domains of death: Evolution cf the apoptosis machinery
    • Aravind L, Dixit VM and Koonin EV (1999) The domains of death: evolution cf the apoptosis machinery. Trends Biochem. Sci. 24: 47-53
    • (1999) Trends Biochem. Sci. , vol.24 , pp. 47-53
    • Aravind, L.1    Dixit, V.M.2    Koonin, E.V.3
  • 41
    • 0030731179 scopus 로고    scopus 로고
    • P53-mediated protective responses to UV irradiation
    • Smith ML and Fornace Jr AJ (1997) p53-mediated protective responses to UV irradiation. Proc. Natl. Acad. Sci. USA 94: 12255-12257
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12255-12257
    • Smith, M.L.1    Fornace A.J., Jr.2
  • 42
    • 0031416522 scopus 로고    scopus 로고
    • Wildtype p53 is required for heat shock and ultraviolet light enhancd repair of a UV-damaged reporter gene
    • McKay BC, Francis MA and Rainbow AJ (1997) Wildtype p53 is required for heat shock and ultraviolet light enhancd repair of a UV-damaged reporter gene. Carcinogenesis 18: 245-249
    • (1997) Carcinogenesis , vol.18 , pp. 245-249
    • McKay, B.C.1    Francis, Ma.2    Rainbow, A.J.3
  • 43
    • 0028919069 scopus 로고
    • Involvement of the p53 tumor suppressor in repair of u.V.-type DNA damage
    • Smith ML, Chen I-T, Zhan Q, O'Connor PM and Fornance Jr AJ (1995) Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage. Oncogene 10:1053-1059
    • (1995) Oncogene , vol.10 , pp. 1053-1059
    • Smith, M.L.1    Chen, I.-T.2    Zhan, Q.3    O'Connor, P.M.4    Fornance A.J., Jr.5
  • 44
    • 0029618266 scopus 로고
    • DNA repair in humans
    • Sancar A (1995) DNA repair in humans. Ann. Rev. Gen. 29: 69-105
    • (1995) Ann. Rev. Gen. , vol.29 , pp. 69-105
    • Sancar, A.1
  • 45
    • 0032404536 scopus 로고    scopus 로고
    • The central executioners of apoptosis: Caspases or mitochondria?
    • Green D and Kroemer G (1998) The central executioners of apoptosis: caspases or mitochondria? Trends Cell Biol. 8: 267-271
    • (1998) Trends Cell Biol. , vol.8 , pp. 267-271
    • Green, D.1    Kroemer, G.2
  • 46
    • 0040298568 scopus 로고    scopus 로고
    • Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
    • Janicke RU, Sprengart ML, Wati MR and Porter AG (1998) Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J. Biol. Chem. 273: 9357-9360
    • (1998) J. Biol. Chem. , vol.273 , pp. 9357-9360
    • Janicke, R.U.1    Sprengart, M.L.2    Wati, M.R.3    Porter, A.G.4
  • 47
    • 0033582526 scopus 로고    scopus 로고
    • Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis
    • Sun X-M, MacFarlane M, Zhuang J, Wolf BB, Green DR and Cohen GM (1999) Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J. Biol. Chem. 274, 5053-5060
    • (1999) J. Biol. Chem. , vol.274 , pp. 5053-5060
    • Sun, X.-M.1    MacFarlane, M.2    Zhuang, J.3    Wolf, B.B.4    Green, D.R.5    Cohen, G.M.6
  • 48
  • 49
    • 0028791446 scopus 로고
    • DNA double-strand break repair and V(D)J recombination: Involvement of DNA-PK
    • Jackson SP and Jeggo PA (1995) DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK. Trends Biochem. Sci. 20: 412-415
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 412-415
    • Jackson, S.P.1    Jeggo, P.A.2
  • 50
    • 0029395076 scopus 로고
    • Menage a trois: Double strand break repair, V(D)J recombination and DNA-PK
    • Jeggo PA, Taccioli GE and Jackson SP (1995) Menage a trois: double strand break repair, V(D)J recombination and DNA-PK. BioEssays 17: 949-957
    • (1995) BioEssays , vol.17 , pp. 949-957
    • Jeggo, P.A.1    Taccioli, G.E.2    Jackson, S.P.3
  • 52
    • 0032416062 scopus 로고    scopus 로고
    • Death by a thousand cuts: An ever increasing list of caspase substrates
    • Stroh C and Schulze-Osthoff K (1998) Death by a thousand cuts: an ever increasing list of caspase substrates. Cell Death Differ. 5: 997-1000
    • (1998) Cell Death Differ. , vol.5 , pp. 997-1000
    • Stroh, C.1    Schulze-Osthoff, K.2
  • 54
    • 0029880959 scopus 로고    scopus 로고
    • Functional interactions between p53 and fre TFIIH complex are affected by tumour-associated mutations
    • Leveillard T, Andera L, Bissonnette N, Schaeffer L, Bracco L, Egly J-M and Wasylyk B (1996) Functional interactions between p53 and fre TFIIH complex are affected by tumour-associated mutations. EMBO J. 15: 1615-1624
    • (1996) EMBO J. , vol.15 , pp. 1615-1624
    • Leveillard, T.1    Andera, L.2    Bissonnette, N.3    Schaeffer, L.4    Bracco, L.5    Egly, J.-M.6    Wasylyk, B.7
  • 55
    • 0031921562 scopus 로고    scopus 로고
    • Commitment and effector phases of the physiological cell death pathway elucidated with respect to bcl-2, caspase, and cyclin-dependent kinase activities
    • Harvey KJ, Blomquist JF and Ucker DS (1998) Commitment and effector phases of the physiological cell death pathway elucidated with respect to bcl-2, caspase, and cyclin-dependent kinase activities. Mol. Cell. Biol. 18: 2912-2922
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2912-2922
    • Harvey, K.J.1    Blomquist, J.F.2    Ucker, D.S.3
  • 57
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller H (1995) Mechanisms and genes of cellular suicide. Science 267: 1445-1449
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.