Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53

Nature Genetics

Volumn 36, Issue 1, 2004, Pages 55-62

  Katayama, Hiroshi ^a   Sasai, Kaori ^a   Kawai, Hidehiko ^b,c   Yuan, Zhi Min ^b   Bondaruk, Jolanta ^a   Suzuki, Fumio ^c   Fujii, Satoshi ^a   Arlinghaus, Ralph B ^a   Czerniak, Bogdan A ^a   Sen, Subrata ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA A KINASE; CISPLATIN; PHOSPHOTRANSFERASE; PROTEIN MDM2; PROTEIN P53; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BLADDER TUMOR; CELL CYCLE G2 PHASE; CELL TRANSFORMATION; CENTROSOME; GENE AMPLIFICATION; GENE OVEREXPRESSION; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; MAMMAL CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; UBIQUITINATION;

APOPTOSIS; CELL CYCLE; HUMANS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; TUMOR SUPPRESSOR PROTEIN P53;

MAMMALIA;

EID: 9144251019     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1279     Document Type: Article

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