-
1
-
-
0025353691
-
Cellular pharmacology of cisplatin: Perspectives on mechanisms of acquired resistance
-
Andrews, P A , and Howell, S B Cellular pharmacology of cisplatin: perspectives on mechanisms of acquired resistance. Cancer Cells, 2: 35-43, 1990
-
(1990)
Cancer Cells
, vol.2
, pp. 35-43
-
-
Andrews, P.A.1
Howell, S.B.2
-
2
-
-
0026385893
-
Cisplatin resistance in human cancers
-
Scanlon, K. J., Kashani-Sabet, M , Tone, T., and Funato, T. Cisplatin resistance in human cancers. Pharmacol. Ther., 52: 385-406, 1991.
-
(1991)
Pharmacol. Ther.
, vol.52
, pp. 385-406
-
-
Scanlon, K.J.1
Kashani-Sabet, M.2
Tone, T.3
Funato, T.4
-
3
-
-
0027136107
-
Platinum analogues in preclinical and clinical development
-
Hamilton, T C , O'Dwyer, P. J., and Ozols, R F. Platinum analogues in preclinical and clinical development. Curr. Opin. Oncol , 5: 1010-1016, 1993.
-
(1993)
Curr. Opin. Oncol
, vol.5
, pp. 1010-1016
-
-
Hamilton, T.C.1
O'Dwyer, P.J.2
Ozols, R.F.3
-
4
-
-
0027233829
-
Cellular accumulation of the anticancer agent cisplatin a review
-
Gately, D P , and Howell, S. B. Cellular accumulation of the anticancer agent cisplatin a review Br J Cancer, 67: 1171-1176, 1993
-
(1993)
Br J Cancer
, vol.67
, pp. 1171-1176
-
-
Gately, D.P.1
Howell, S.B.2
-
5
-
-
0027087299
-
Reduced drug accumulation as a major mechanism of acquired resistance to cisplatin in a human ovarian carcinoma cell line: Circumvention studies using novel platinum(II) and (IV) ammine/amine complexes
-
Loh, S. Y , Mistry, P , Kelland, L R., Abel, G., Murrer, B. A., and Harrap, K R. Reduced drug accumulation as a major mechanism of acquired resistance to cisplatin in a human ovarian carcinoma cell line: circumvention studies using novel platinum(II) and (IV) ammine/amine complexes. Br. J. Cancer, 66: 1109-1115, 1992
-
(1992)
Br. J. Cancer
, vol.66
, pp. 1109-1115
-
-
Loh, S.Y.1
Mistry, P.2
Kelland, L.R.3
Abel, G.4
Murrer, B.A.5
Harrap, K.R.6
-
6
-
-
0025816320
-
The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines
-
Mistry, P , Kelland, L R., Abel, G., Sidhar, S., and Harrap, K. R. The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines. Br. J. Cancer, 64: 215-220, 1991.
-
(1991)
Br. J. Cancer
, vol.64
, pp. 215-220
-
-
Mistry, P.1
Kelland, L.R.2
Abel, G.3
Sidhar, S.4
Harrap, K.R.5
-
7
-
-
0024988359
-
Activation of programmed cell death by anticancer agents: Cisplatin as a model system
-
Eastman A. Activation of programmed cell death by anticancer agents: cisplatin as a model system. Cancer Cells, 2: 275-280, 1990.
-
(1990)
Cancer Cells
, vol.2
, pp. 275-280
-
-
Eastman, A.1
-
8
-
-
0028144364
-
The role of apoptosis in cell killing by cisplatin: A flow cytometric study
-
Ormerod, M. G., Orr, R. M., and Peacock, J. H The role of apoptosis in cell killing by cisplatin: a flow cytometric study. Br. J. Cancer. 69: 93-100, 1994.
-
(1994)
Br. J. Cancer.
, vol.69
, pp. 93-100
-
-
Ormerod, M.G.1
Orr, R.M.2
Peacock, J.H.3
-
9
-
-
0028204160
-
DNA strand breaks: The DNA template alterations that trigger p53-depeadem DNA damage response pathways
-
Nelson, W. G., and Kastan, M B. DNA strand breaks: the DNA template alterations that trigger p53-depeadem DNA damage response pathways. Mol. Cell. Biol., 14: 1815-1823, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1815-1823
-
-
Nelson, W.G.1
Kastan, M.B.2
-
10
-
-
0028456527
-
Relationship of p53 to the control of apoptotic cell death
-
Oren, M. Relationship of p53 to the control of apoptotic cell death. Cancer Biol., 5: 221-227, 1994.
-
(1994)
Cancer Biol.
, vol.5
, pp. 221-227
-
-
Oren, M.1
-
11
-
-
0027210981
-
Gain of function mutations in p53
-
Dittmer, D., Pati, S., Zambetti, G., Chu, S., Teresky, A. K., Moore, M., Finlay, C., and Levine, A. J. Gain of function mutations in p53. Nature Genet., 4: 42-46, 1993.
-
(1993)
Nature Genet.
, vol.4
, pp. 42-46
-
-
Dittmer, D.1
Pati, S.2
Zambetti, G.3
Chu, S.4
Teresky, A.K.5
Moore, M.6
Finlay, C.7
Levine, A.J.8
-
12
-
-
0028025563
-
Apoptosis in cancer therapy: Crossing the threshold
-
Fisher, D. E. Apoptosis in cancer therapy: crossing the threshold. Cell, 78: 539-542, 1994.
-
(1994)
Cell
, vol.78
, pp. 539-542
-
-
Fisher, D.E.1
-
13
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of human bax gene
-
Miyashita, T., and Reed, J C. Tumor suppressor p53 is a direct transcriptional activator of human bax gene. Cell, 80: 293-299, 1995.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
14
-
-
0028040019
-
Bcl-2 and the regulation of programmed cell death
-
Reed, J. C. Bcl-2 and the regulation of programmed cell death. J. Cell Biol , 124: 1-6, 1994.
-
(1994)
J. Cell Biol
, vol.124
, pp. 1-6
-
-
Reed, J.C.1
-
15
-
-
0028017880
-
Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system
-
Sato, T., Hanada, M., Bodrug, S., Irie, S., Iwama, N., Boise, L. H , Thompson, C. B., Golemis, E., Fong, L , Wang, H-G., and Reed, J. C. Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system. Proc. Natl. Acad. Sci. USA, 91: 9238-9242, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9238-9242
-
-
Sato, T.1
Hanada, M.2
Bodrug, S.3
Irie, S.4
Iwama, N.5
Boise, L.H.6
Thompson, C.B.7
Golemis, E.8
Fong, L.9
Wang, H.-G.10
Reed, J.C.11
-
16
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Oltvai, Z. N., Milliman, C. L , and Korsmeyer, S. J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell, 74: 609-619, 1993.
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
17
-
-
0000883719
-
Measurement of strand breaks and cross-links by alkaline elution
-
E. C Freidberg and P. C. Hanawalt (eds.), New York: Marcel Dekker
-
Kohn, K. W., Ewing, R. A., Erickson, L. C., and Zwelling, L. Measurement of strand breaks and cross-links by alkaline elution. In: E. C Freidberg and P. C. Hanawalt (eds.), DNA Repair: A Laboratory Manual of Research Procedures, pp. 379-401. New York: Marcel Dekker, 1981.
-
(1981)
DNA Repair: A Laboratory Manual of Research Procedures
, pp. 379-401
-
-
Kohn, K.W.1
Ewing, R.A.2
Erickson, L.C.3
Zwelling, L.4
-
18
-
-
0027215123
-
Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland
-
Donghi, R., Longoni, A., Pilotti, S., Michieli, P , Della Porta, G., and Pierotti, M A. Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland. J. Clin. Invest., 91. 1753-1760, 1993.
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 1753-1760
-
-
Donghi, R.1
Longoni, A.2
Pilotti, S.3
Michieli, P.4
Della Porta, G.5
Pierotti, M.A.6
-
19
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.), 227: 680-685, 1970.
-
(1970)
Nature (Lond.)
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
20
-
-
0028596574
-
A role for the human DNA repair enzyme HAPI in cellular protection against DNA damaging agents and hypoxic stress
-
Walker, L. J., Craig, R. B., Harris, A. L., and Hickson, D. A role for the human DNA repair enzyme HAPI in cellular protection against DNA damaging agents and hypoxic stress. Nucleic Acids Res., 22: 4884-4889, 1994.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 4884-4889
-
-
Walker, L.J.1
Craig, R.B.2
Harris, A.L.3
Hickson, D.4
-
21
-
-
0028335717
-
Tumor suppressor p53 is a regulator of bcl-2 and box gene expression in vitro and in vivo
-
Miyashita, T., Krajewski, S., Krajewska, M., Wang, H. G., Lin, H. K., Liebermann, D. A., Hoffman, B., and Reed, J. C. Tumor suppressor p53 is a regulator of bcl-2 and box gene expression in vitro and in vivo. Oncogene, 9: 1799-1805, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 1799-1805
-
-
Miyashita, T.1
Krajewski, S.2
Krajewska, M.3
Wang, H.G.4
Lin, H.K.5
Liebermann, D.A.6
Hoffman, B.7
Reed, J.C.8
-
22
-
-
0026776342
-
Specific repression of granulocyte-macrophage and granulocyte colony-stimulating factor gene expression in interleukin-1-stimulated endothelial cells with antisense oligodeoxynucleotides
-
Segal, G. M., Smith, T. D., Heinrich, M. C., Ey, F. S., and Bagby, G. C. Jr. Specific repression of granulocyte-macrophage and granulocyte colony-stimulating factor gene expression in interleukin-1-stimulated endothelial cells with antisense oligodeoxynucleotides. Blood, 80: 609-616, 1992
-
(1992)
Blood
, vol.80
, pp. 609-616
-
-
Segal, G.M.1
Smith, T.D.2
Heinrich, M.C.3
Ey, F.S.4
Bagby Jr., G.C.5
-
23
-
-
0026535237
-
Functional domains of wild-type and mutant p53 proteins involved in transcriptional regulation transdominant inhibition, and transformation suppression
-
Unger, T., Nau, M. M., Segal, S., and Minna, J. D Functional domains of wild-type and mutant p53 proteins involved in transcriptional regulation transdominant inhibition, and transformation suppression. EMBO J., 11: 1383-1390, 1992.
-
(1992)
EMBO J.
, vol.11
, pp. 1383-1390
-
-
Unger, T.1
Nau, M.M.2
Segal, S.3
Minna, J.D.4
-
24
-
-
0028292480
-
Identification of a p53-dependent negative response element in the bcl-2 gene
-
Miyashita, T , Harigai, M., Hanada, M., and Reed, J. C. Identification of a p53-dependent negative response element in the bcl-2 gene. Cancer Res., 54: 3131-3135, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 3131-3135
-
-
Miyashita, T.1
Harigai, M.2
Hanada, M.3
Reed, J.C.4
-
25
-
-
0025606976
-
Nuclear retinoic acid receptors: Cloning, analysis, and function
-
Phahl, M., Tzukerman, M., Zhang, X., Lehmann, J., Hermann, T., Wills, K. N., and Graupne, G. Nuclear retinoic acid receptors: cloning, analysis, and function Methods Enzymol., 189: 256-270, 1990.
-
(1990)
Methods Enzymol.
, vol.189
, pp. 256-270
-
-
Phahl, M.1
Tzukerman, M.2
Zhang, X.3
Lehmann, J.4
Hermann, T.5
Wills, K.N.6
Graupne, G.7
-
26
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt, M. S , Bennett, W. P., Hollstein, M., and Harris, C. C Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res., 54: 4855-4878, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Harris, C.C.4
-
27
-
-
0028453472
-
The role of p53 in tumor progression
-
Blondal, J. A., and Benchimol, S. The role of p53 in tumor progression. Semin. Cancer Biol , 5: 177-186, 1994.
-
(1994)
Semin. Cancer Biol
, vol.5
, pp. 177-186
-
-
Blondal, J.A.1
Benchimol, S.2
-
28
-
-
0026702212
-
Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element
-
Zambetti, G. P., Bargonetti, J., and Walker. J Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element. Genes & Dev., 6: 1143-1152, 1992.
-
(1992)
Genes & Dev.
, vol.6
, pp. 1143-1152
-
-
Zambetti, G.P.1
Bargonetti, J.2
Walker, J.3
-
29
-
-
0027439174
-
p53: A target for new anticancer drugs or a target for old drugs?
-
Brown, R. p53: a target for new anticancer drugs or a target for old drugs? Ann. Oncol., 4: 623-629, 1993.
-
(1993)
Ann. Oncol.
, vol.4
, pp. 623-629
-
-
Brown, R.1
-
30
-
-
0026523778
-
Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line
-
Shaw, P., Bovey, R., Tardy, S., Sahli, R., Sordat, B., and Costa, J. Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line. Proc. Natl. Acad Sci. USA, 89. 4495-4499, 1992.
-
(1992)
Proc. Natl. Acad Sci. USA
, vol.89
, pp. 4495-4499
-
-
Shaw, P.1
Bovey, R.2
Tardy, S.3
Sahli, R.4
Sordat, B.5
Costa, J.6
-
31
-
-
0027369120
-
Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines
-
Brown, R., Clugston, C , Burns, P., Edlin, A., Vasey, P., Vojtesek, B., Kaye, S. B. Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines Int. J Cancer, 55: 678-684, 1993.
-
(1993)
Int. J Cancer
, vol.55
, pp. 678-684
-
-
Brown, R.1
Clugston, C.2
Burns, P.3
Edlin, A.4
Vasey, P.5
Vojtesek, B.6
Kaye, S.B.7
-
32
-
-
0028319289
-
Concomitant p53 gene mutation and increased radiosensitivity in rat lung embryo epithelial cells during neoplastic development
-
Biard, D S. F , Martin, M., Le Rhum, Y., Duthu, A., Lefaix, J L., May, E., and May, P. Concomitant p53 gene mutation and increased radiosensitivity in rat lung embryo epithelial cells during neoplastic development. Cancer Res., 54: 3361-3364, 1994
-
(1994)
Cancer Res.
, vol.54
, pp. 3361-3364
-
-
Biard, D.S.F.1
Martin, M.2
Le Rhum, Y.3
Duthu, A.4
Lefaix, J.L.5
May, E.6
May, P.7
-
33
-
-
0028171454
-
p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents
-
Fan, S , El-Deiry, W S., Bae, I., Freeman, J., Jondle, D., Bhatia, K., Fornace, A. J , Magrath, I., Kohn, K. W , and O'Connor, M. p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents. Cancer Res., 54: 5824-5830, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 5824-5830
-
-
Fan, S.1
El-Deiry, W.S.2
Bae, I.3
Freeman, J.4
Jondle, D.5
Bhatia, K.6
Fornace, A.J.7
Magrath, I.8
Kohn, K.W.9
O'Connor, M.10
-
34
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
Washington DC
-
Lowe, S. W., Bodis, S , McClatchey, A., Remington, L., Ruley, H. E., Fisher, D. E., Housman, D. E., and Jacks, T. p53 status and the efficacy of cancer therapy in vivo Science (Washington DC), 266: 807-810, 1994.
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
Remington, L.4
Ruley, H.E.5
Fisher, D.E.6
Housman, D.E.7
Jacks, T.8
-
36
-
-
0025367297
-
Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines
-
Bartek, J., Iggo, R., and Lane, D P. Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines. Oncogene, 5: 893-899, 1990.
-
(1990)
Oncogene
, vol.5
, pp. 893-899
-
-
Bartek, J.1
Iggo, R.2
Lane, D.P.3
-
37
-
-
0026708148
-
Mutant conformation of p53. Precise epitope mapping using a filamentous phage epitope library
-
Stephen, C. W., and Lane, D. P. Mutant conformation of p53. Precise epitope mapping using a filamentous phage epitope library. J. Mol Biol., 225: 577-583, 1992
-
(1992)
J. Mol Biol.
, vol.225
, pp. 577-583
-
-
Stephen, C.W.1
Lane, D.P.2
-
38
-
-
0028294605
-
1 arrest and apoptosis
-
1 arrest and apoptosis Cancer Res , 54: 1169-1174, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 1169-1174
-
-
El-Deiry, W.S.1
Harper, J.W.2
O'Connor, P.M.3
Velculescu, V.E.4
Canman, C.E.5
Jackman, J.6
Pietenpol, J.A.7
Burrell, M.8
Hill, D.E.9
Wang, Y.10
Wiman, K.G.11
Mercer, W.E.12
Kastan, M.B.13
Kohn, K.W.14
Elledge, S.J.15
Kinzler, K.W.16
Volgestein, B.17
-
39
-
-
0027944228
-
Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis
-
Zhan, Q., Fan, S., Bae, I , Guillouf, C., Liebermann, D. A., O'Connor P. M , and Fornace, A J. Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis. Oncogene, 9, 3743-3751, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 3743-3751
-
-
Zhan, Q.1
Fan, S.2
Bae, I.3
Guillouf, C.4
Liebermann, D.A.5
O'Connor, P.M.6
Fornace, A.J.7
-
40
-
-
0028335717
-
Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
-
Miyashita, T , Krajewski, S., Krajewska, M., Wang, H. G., Lin, H. K., Liebermann, D. A., Hoffman, B , and Reed, J. C. Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo Oncogene, 9: 1799-1805, 1994
-
(1994)
Oncogene
, vol.9
, pp. 1799-1805
-
-
Miyashita, T.1
Krajewski, S.2
Krajewska, M.3
Wang, H.G.4
Lin, H.K.5
Liebermann, D.A.6
Hoffman, B.7
Reed, J.C.8
|