p53 and regulation of DNA damage recognition during nucleotide excision repair

DNA Repair

Volumn 2, Issue 9, 2003, Pages 947-954

  Adimoolam, Shanthi ^a   Ford, James M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

DDB2; DNA damage; Global genomic repair; Nucleotide excision repair; p53; XPC

Indexed keywords

BRCA1 PROTEIN; CYCLOBUTANE; GENE PRODUCT; HELICASE; PROTEIN C JUN; PROTEIN P53; PYRIMIDINE DIMER; PYRIMIDINONE DERIVATIVE; TRANSCRIPTION FACTOR;

APOPTOSIS; BINDING AFFINITY; CELL CYCLE; CHROMATIN STRUCTURE; DNA ADDUCT; DNA BINDING; DNA DAMAGE; DNA REPAIR; DNA STRAND; DNA STRUCTURE; ENZYME ACTIVITY; EXCISION REPAIR; FAMILIAL CANCER; FIBROBLAST; GENE CONTROL; GENE EXPRESSION; GENE MUTATION; GENE OVEREXPRESSION; GENOME; HUMAN; MUTAGENESIS; ONCOGENE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SHORT SURVEY; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; ULTRAVIOLET IRRADIATION;

ZIZIPHUS MAURITIANA;

EID: 0042379999     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1568-7864(03)00087-9     Document Type: Short Survey

References (64)

1. Hollstein M., Sidransky D., Vogelstein B., Harris C.C. p53 mutations in human cancers. Science. 253:1991;49-53.
2. Vousden K.H., Lu X. Live or let die: the cell's response to p53. Nat. Rev. Cancer. 2:2002;594-604.
3. Levine A.J. p53, the cellular gatekeeper for growth and division. Cell. 88:1997;323-331.
4. Hainaut P., Hollstein M. p53 and human cancer: the first ten thousand mutations. Adv. Cancer Res. 77:2000;81-137.
5. Zhao R., Gish K., Murphy M., Yin Y., Notterman D., Hoffman W.H., Tom E., Mack D.H., Levine A.J. Analysis of p53-regulated gene expression patterns using oligonucleotide arrays. Genes Dev. 14:2000;981-993.
6. Oren M. Regulation of the p53 tumor suppressor protein. J. Biol. Chem. 274:1999;36031-36034.
7. Harper J.W., Adami G.R., Wei N., Keyomarsi K., Elledge S.J. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell. 75:1993;805-816.
8. Caelles C., Helmberg A., Karin M. p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature. 370:1994;220-223.
9. Dumont P., Leu J.I., Della Pietra A.C., George D.L., Murphy M. The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat. Genet. 33:2003;357-365.
10. Kastan M.B., Onyekwere O., Sidransky D., Vogelstein B., Craig R.W. Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 51:1991;6304-6311.
11. de Laat W.L., Jaspers N.G., Hoeijmakers J.H. Molecular mechanism of nucleotide excision repair. Genes Dev. 13:1999;768-785.
12. Hanawalt P.C. Subpathways of nucleotide excision repair and their regulation. Oncogene. 21:2002;8949-8956.
13. Ford J.M., Hanawalt P.C. Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance. Proc. Natl. Acad. Sci. U.S.A. 92:1995;8876-8880.
14. Smith M.L., Chen I.T., Zhan Q., O'Connor P.M., Fornace A.J. Jr. Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage. Oncogene. 10:1995;1053-1059.
15. Wang X.W., Yeh H., Schaeffer L., Roy R., Moncollin V., Egly J.M., Wang Z., Freidberg E.C., Evans M.K., Taffe B.G., Bohr V.A., Weeda G., Hoeijmakers J.H.J., Forrester K., Harris C.C. p53 modulation of TFIIH-associated nucleotide excision repair activity. Nat. Genet. 10:1995;188-195.
16. Ford J.M., Hanawalt P.C. Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts. J. Biol. Chem. 272:1997;28073-28080.
17. Li G., Ho V.C., Mitchell D.L., Trotter M.J., Tron V.A. Differentiation-dependent p53 regulation of nucleotide excision repair in keratinocytes. Am. J. Pathol. 150:1997;1457-1464.
18. Ford J.M., Baron E.L., Hanawalt P.C. Human fibroblasts expressing the human papillomavirus E6 gene are deficient in global genomic nucleotide excision repair and sensitive to ultraviolet irradiation. Cancer Res. 58:1998;599-603.
19. Therrien J.P., Drouin R., Baril C., Drobetsky E.A. Human cells compromised for p53 function exhibit defective global and transcription-coupled nucleotide excision repair, whereas cells compromised for pRb function are defective only in global repair. Proc. Natl. Acad. Sci. U.S.A. 96:1999;15038-15043.
20. Mahdy M.A.El, Hamada F.M., Wani M.A., Zhu Q., Wani A.A. p53-degradation by HPV-16 E6 preferentially affects the removal of cyclobutane pyrimidine dimers from non-transcribed strand and sensitizes mammary epithelial cells to UV-irradiation. Mutat. Res. 459:2000;135-145.
21. Smith M.L., Ford J.M., Hollander M.C., Bortnick R.A., Amundson S.A., Seo Y.R., Deng C.X., Hanawalt P.C., Fornace A.J. Jr. p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes. Mol. Cell. Biol. 20:2000;3705-3714.
22. Bowman K.K., Sicard D.M., Ford J.M., Hanawalt P.C. Reduced global genomic repair of ultraviolet light-induced cyclobutane pyrimidine dimers in simian virus 40-transformed human cells. Mol. Carcinog. 29:2000;17-24.
23. Adimoolam S., Lin C.X., Ford J.M. The p53-regulated cyclin-dependent kinase inhibitor, p21 (cip1, waf1, sdi1), is not required for global genomic and transcription-coupled nucleotide excision repair of UV-induced DNA photoproducts. J. Biol. Chem. 276:2001;25813-25822.
24. Lloyd D.R., Hanawalt P.C. p53-dependent global genomic repair of benzo[a]pyrene-7,8-diol-9,10-epoxide adducts in human cells. Cancer Res. 60:2000;517-521.
25. Wani M.A., Zhu Q., El Mahdy M., Venkatachalam S., Wani A.A. Enhanced sensitivity to anti-benzo[a]pyrene-diol-epoxide DNA damage correlates with decreased global genomic repair attributable to abrogated p53 function in human cells. Cancer Res. 60:2000;2273-2280.
26. Lloyd D.R., Hanawalt P.C. p53 controls global nucleotide excision repair of low levels of structurally diverse benzo[g]chrysene-DNA adducts in human fibroblasts. Cancer Res. 62:2002;5288-5294.
27. Jayaraman J., Prives C. Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus. Cell. 81:1995;1021-1029.
28. Hwang B.J., Ford J.M., Hanawalt P.C., Chu G. Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair. Proc. Natl. Acad. Sci. U.S.A. 96:1999;424-428.
29. Adimoolam S., Ford J.M. p53 and DNA damage-inducible expression of the xeroderma pigmentosum group C gene. Proc. Natl. Acad. Sci. U.S.A. 99:2002;12985-12990.
30. Amundson S.A., Patterson A., Do K.T., Fornace A.J. A nucleotide excision repair master-switch: p53 regulated coordinate induction of global genomic repair genes. Cancer Biol Ther. 1:2002;145-149.
31. Tang J.Y., Hwang B.J., Ford J.M., Hanawalt P.C., Chu G. Xeroderma pigmentosum p48 gene enhances global genomic repair and suppresses UV-induced mutagenesis. Mol. Cell. 5:2000;737-744.
32. Wakasugi M., Kawashima A., Morioka H., Linn S., Sancar A., Mori T., Nikaido O., Matsunaga T. DDB accumulates at DNA damage sites immediately after UV irradiation and directly stimulates nucleotide excision repair. J. Biol. Chem. 277:2002;1637-1640.
33. Fitch M.E., Cross I.V., Turner S.J., Adimoolam S., Lin C.X., Williams K.G., Ford J.M. The DDB2 nucleotide excision repair gene product p48 enhances global genomic repair in p53 deficient human fibroblasts. DNA Repair. 2:2003;819-826.
34. Tan T., Chu G. p53 binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice. Mol. Cell. Biol. 22:2002;3247-3254.
35. Sugasawa K., Okamoto T., Shimizu Y., Masutani C., Iwai S., Hanaoka F. A multistep damage recognition mechanism for global genomic nucleotide excision repair. Genes Dev. 15:2001;507-521.
36. Venema J., van Hoffen A., Karcagi V., Natarajan A.T., van Zeeland A.A., Mullenders L.H. Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes. Mol. Cell. Biol. 11:1991;4128-4134.
37. Venema J., van Hoffen A., Natarajan A.T., van Zeeland A.A., Mullenders L.H. The residual repair capacity of xeroderma pigmentosum complementation group C fibroblasts is highly specific for transcriptionally active DNA. Nucleic Acids Res. 18:1990;443-448.
38. Emmert S., Kobayashi N., Khan S.G., Kraemer K.H. The xeroderma pigmentosum group C gene leads to selective repair of cyclobutane pyrimidine dimers rather than 6-4 photoproducts. Proc. Natl. Acad. Sci. U.S.A. 97:2000;2151-2156.
39. Batty D., Rapic'-Otrin V., Levine A.S., Wood R.D. Stable binding of human XPC complex to irradiated DNA confers strong discrimination for damaged sites. J. Mol. Biol. 300:2000;275-290.
40. Kusumoto R., Masutani C., Sugasawa K., Iwai S., Araki M., Uchida A., Mizukoshi T., Hanaoka F. Diversity of the damage recognition step in the global genomic nucleotide excision repair in vitro. Mutat. Res. 485:2001;219-227.
41. Sweder K., Madura K. Regulation of repair by the 26S proteasome. J. Biomed. Biotechnol. 2:2002;94-105.
42. Lommel L., Ortolan T., Chen L., Madura K., Sweder K.S. Proteolysis of a nucleotide excision repair protein by the 26S proteasome. Curr. Genet. 42:2002;9-20.
43. You J.S., Wang M., Lee S.H. Biochemical analysis of the damage recognition process in nucleotide excision repair. J. Biol. Chem. 278:2003;7476-7485.
44. Fujiwara Y., Masutani C., Mizukoshi T., Kondo J., Hanaoka F., Iwai S. Characterization of DNA recognition by the human UV-damaged DNA-binding protein. J. Biol. Chem. 274:1999;20027-20033.
45. Rapic-Otrin V., McLenigan M.P., Bisi D.C., Gonzalez M., Levine A.S. Sequential binding of UV DNA damage binding factor and degradation of the p48 subunit as early events after UV irradiation. Nucleic Acids Res. 30:2002;2588-2598.
46. Fitch M.E., Cross I.V., Ford J.M. p53 responsive nucleotide excision repair gene products p48 and XPC, but not p53, localize to sites of UV-irradiation induced DNA damage, in vivo. Carcinogenesis. 24:2003;843-850.
47. Volker M., Mone M.J., Karmakar P., van Hoffen A., Schul W., Vermeulen W., Hoeijmakers J.H., van Driel R., van Zeeland A.A., Mullenders L.H. Sequential assembly of the nucleotide excision repair factors in vivo. Mol. Cell. 8:2001;213-224.
48. Lakhani S.R., van de Vijver M.J., Jacquemier J., Anderson T.J., Osin P.P., McGuffog L., Easton D.F. The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2. J. Clin. Oncol. 20:2002;2310-2318.
49. Crook T., Brooks L.A., Crossland S., Osin P., Barker K.T., Waller J., Philp E., Smith P.D., Yulug I., Peto J., Parker G., Allday M.J., Crompton M.R., Gusterson B.A. p53 mutation with frequent novel condons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours. Oncogene. 17:1998;1681-1689.
50. Hakem R., de la Pompa J.L., Elia A., Potter J., Mak T.W. Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation. Nat. Genet. 16:1997;298-302.
51. Arizti P., Fang L., Park I., Yin Y., Solomon E., Ouchi T., Aaronson S.A., Lee S.W. Tumor suppressor p53 is required to modulate BRCA1 expression. Mol. Cell. Biol. 20:2000;7450-7459.
52. MacLachlan T.K., Dash B.C., Dicker D.T., El Deiry W.S. Repression of BRCA1 through a feedback loop involving p53. J. Biol. Chem. 275:2000; 31869-31875.
53. Hartman A.R., Ford J.M. BRCA1 induces DNA damage recognition factors and enhances nucleotide excision repair. Nat. Genet. 32:2002;180-184.
54. Mathonnet G., Leger C., Desnoyers J., Drouin R., Therrien J.P., Drobetsky E.A. UV wavelength-dependent regulation of transcription-coupled nucleotide excision repair in p53-deficient human cells. Proc. Natl. Acad. Sci. U.S.A. 100:2003;7219-7224.
55. Rubbi C.P., Milner J. p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage. EMBO J. 22:2003;975-986.
56. Otrin V.R., Kuraoka I., Nardo T., McLenigan M., Eker A.P., Stefanini M., Levine A.S., Wood R.D. Relationship of the xeroderma pigmentosum group E DNA repair defect to the chromatin and DNA binding proteins UV-DDB and replication protein A. Mol. Cell. Biol. 18:1998;3182-3190.
57. Smith M.L., Seo Y.R. p53 regulation of DNA excision repair pathways. Mutagenesis. 17:2002;149-156.
58. Offer H., Erez N., Zurer I., Tang X., Milyavsky M., Goldfinger N., Rotter V. The onset of p53-dependent DNA repair or apoptosis is determined by the level of accumulated damaged DNA. Carcinogenesis. 23:2002;1025-1032.
59. Offer H., Wolkowicz R., Matas D., Blumenstein S., Livneh Z., Rotter V. Direct involvement of p53 in the base excision repair pathway of the DNA repair machinery. FEBS Lett. 450:1999;197-204.
60. Offer H., Zurer I., Banfalvi G., Reha'k M., Falcovitz A., Milyavsky M., Goldfinger N., Rotter V. p53 modulates base excision repair activity in a cell cycle-specific manner after genotoxic stress. Cancer Res. 61:2001;88-96.
61. Offer H., Milyavsky M., Erez N., Matas D., Zurer I., Harris C.C., Rotter V. Structural and functional involvement of p53 in BER in vitro and in vivo. Oncogene. 20:2001;581-589.
62. Zhou J., Ahn J., Wilson S.H., Prives C. A role for p53 in base excision repair. EMBO J. 20:2001;914-923.
63. Seo Y.R., Fishel M.L., Amundson S., Kelley M.R., Smith M.L. Implication of p53 in base excision DNA repair: in vivo evidence. Oncogene. 21:2002;731-737.
64. Fornace A.J. Jr., Zmudzka B., Hollander M.C., Wilson S.H. Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells. Mol. Cell. Biol. 9:1989;851-853.