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Volumn 48, Issue 2, 2005, Pages 185-195

Macrophages and neurodegeneration

Author keywords

Axonal loss; Blood brain barrier; Experimental allergic encephalomyelitis (EAE); Macrophages; Monocyte migration; Multiple sclerosis; Neurodegeneration

Indexed keywords

AMINOGUANINE; AMYLOID PRECURSOR PROTEIN; ANTIOXIDANT; BILIRUBIN; CALCIUM CHANNEL BLOCKING AGENT; CATALASE; CYTOKINE; FLAVONOID; FREE RADICAL; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; HEMOXYGENASE 1; HYDROGEN PEROXIDE; HYDROXYL RADICAL; INTERLEUKIN 1; INTERLEUKIN 6; LUTEOLIN; METALLOPROTEINASE; METALLOTHIONEIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; OXYGENASE; REACTIVE OXYGEN METABOLITE; SODIUM CHANNEL BLOCKING AGENT; SUPEROXIDE; SUPEROXIDE DISMUTASE; THIOCTIC ACID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; URIC ACID;

EID: 17844381010     PISSN: 01650173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresrev.2004.12.008     Document Type: Conference Paper
Times cited : (222)

References (189)
  • 1
    • 0033992335 scopus 로고    scopus 로고
    • Dexanabinol (HU-211) effect on experimental autoimmune encephalomyelitis: Implications for the treatment of acute relapses of multiple sclerosis
    • A. Achiron, S. Miron, V. Lavie, R. Margalit, and A. Biegon Dexanabinol (HU-211) effect on experimental autoimmune encephalomyelitis: implications for the treatment of acute relapses of multiple sclerosis J. Neuroimmunol. 102 2000 26 31
    • (2000) J. Neuroimmunol. , vol.102 , pp. 26-31
    • Achiron, A.1    Miron, S.2    Lavie, V.3    Margalit, R.4    Biegon, A.5
  • 2
    • 0343750676 scopus 로고    scopus 로고
    • Axonal damage induced by cerebrospinal fluid from patients with relapsing-remitting multiple sclerosis
    • A. Alcazar, I. Regidor, J. Masjuan, M. Salinas, and J.C. Alvarez-Cermeno Axonal damage induced by cerebrospinal fluid from patients with relapsing-remitting multiple sclerosis J. Neuroimmunol. 104 2000 58 67
    • (2000) J. Neuroimmunol. , vol.104 , pp. 58-67
    • Alcazar, A.1    Regidor, I.2    Masjuan, J.3    Salinas, M.4    Alvarez-Cermeno, J.C.5
  • 4
    • 0041589811 scopus 로고    scopus 로고
    • Early damage of sympathetic neurons after co-culture with macrophages: A model of neuronal injury in vitro
    • R.M. Arantes, S. Lourenssen, C.R. Machado, and M.G. Blennerhassett Early damage of sympathetic neurons after co-culture with macrophages: a model of neuronal injury in vitro NeuroReport 11 2000 177 181
    • (2000) NeuroReport , vol.11 , pp. 177-181
    • Arantes, R.M.1    Lourenssen, S.2    MacHado, C.R.3    Blennerhassett, M.G.4
  • 6
    • 0028066844 scopus 로고
    • Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins
    • D. Baker, D. Butler, B.J. Scallon, J.K. ONeill, J.L. Turk, and M. Feldmann Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins Eur. J. Immunol. 24 1994 2040 2048
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2040-2048
    • Baker, D.1    Butler, D.2    Scallon, B.J.3    Oneill, J.K.4    Turk, J.L.5    Feldmann, M.6
  • 8
    • 0038412627 scopus 로고    scopus 로고
    • Lipoprotein oxidation, plasma total antioxidant capacity and homocysteine level in patients with multiple sclerosis
    • H.T. Besler, and S. Comoglu Lipoprotein oxidation, plasma total antioxidant capacity and homocysteine level in patients with multiple sclerosis Nutr. Neurosci. 6 2003 189 196
    • (2003) Nutr. Neurosci. , vol.6 , pp. 189-196
    • Besler, H.T.1    Comoglu, S.2
  • 9
    • 0024325294 scopus 로고
    • N-acetyl-l-aspartic acid: A literature review of a compound prominent in 1H-NMR spectroscopic studies of brain
    • D.L. Birken, and W.H. Oldendorf N-acetyl-l-aspartic acid: a literature review of a compound prominent in 1H-NMR spectroscopic studies of brain Neurosci. Biobehav. Rev. 13 1989 23 31
    • (1989) Neurosci. Biobehav. Rev. , vol.13 , pp. 23-31
    • Birken, D.L.1    Oldendorf, W.H.2
  • 10
    • 0034026912 scopus 로고    scopus 로고
    • Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation
    • A. Bitsch, J. Schuchardt, S. Bunkowski, T. Kuhlmann, and W. Bruck Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation Brain 123 Pt. 6 2000 1174 1183
    • (2000) Brain , vol.123 , Issue.6 PART , pp. 1174-1183
    • Bitsch, A.1    Schuchardt, J.2    Bunkowski, S.3    Kuhlmann, T.4    Bruck, W.5
  • 11
    • 0036136536 scopus 로고    scopus 로고
    • N-acetylaspartate is an axon-specific marker of mature white matter in vivo: A biochemical and immunohistochemical study on the rat optic nerve
    • C. Bjartmar, J. Battistuta, N. Terada, E. Dupree, and B.D. Trapp N-acetylaspartate is an axon-specific marker of mature white matter in vivo: a biochemical and immunohistochemical study on the rat optic nerve Ann. Neurol. 51 2002 51 58
    • (2002) Ann. Neurol. , vol.51 , pp. 51-58
    • Bjartmar, C.1    Battistuta, J.2    Terada, N.3    Dupree, E.4    Trapp, B.D.5
  • 12
    • 0033663894 scopus 로고    scopus 로고
    • Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients
    • C. Bjartmar, G. Kidd, S. Mork, R. Rudick, and B.D. Trapp Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients Ann. Neurol. 48 2000 893 901
    • (2000) Ann. Neurol. , vol.48 , pp. 893-901
    • Bjartmar, C.1    Kidd, G.2    Mork, S.3    Rudick, R.4    Trapp, B.D.5
  • 13
    • 0037200807 scopus 로고    scopus 로고
    • Sodium channel Na(v)1.6 is expressed along nonmyelinated axons and it contributes to conduction
    • J.A. Black, M. Renganathan, and S.G. Waxman Sodium channel Na(v)1.6 is expressed along nonmyelinated axons and it contributes to conduction Brain Res. Mol. Brain Res. 105 2002 19 28
    • (2002) Brain Res. Mol. Brain Res. , vol.105 , pp. 19-28
    • Black, J.A.1    Renganathan, M.2    Waxman, S.G.3
  • 15
    • 0028873068 scopus 로고
    • Interleukin-6 production by Schwann cells and induction in sciatic nerve injury
    • L.M. Bolin, A.N. Verity, J.E. Silver, E.M. Shooter, and J.S. Abrams Interleukin-6 production by Schwann cells and induction in sciatic nerve injury J. Neurochem. 64 1995 850 858
    • (1995) J. Neurochem. , vol.64 , pp. 850-858
    • Bolin, L.M.1    Verity, A.N.2    Silver, J.E.3    Shooter, E.M.4    Abrams, J.S.5
  • 16
    • 0017317639 scopus 로고
    • Continuous conduction in demyelinated mammalian nerve fibers
    • H. Bostock, and T.A. Sears Continuous conduction in demyelinated mammalian nerve fibers Nature 263 1976 786 787
    • (1976) Nature , vol.263 , pp. 786-787
    • Bostock, H.1    Sears, T.A.2
  • 17
    • 0017902740 scopus 로고
    • The internodal axon membrane: Electrical excitability and continuous conduction in segmental demyelination
    • H. Bostock, and T.A. Sears The internodal axon membrane: electrical excitability and continuous conduction in segmental demyelination J. Physiol. 280 1978 273 301
    • (1978) J. Physiol. , vol.280 , pp. 273-301
    • Bostock, H.1    Sears, T.A.2
  • 18
    • 0030984075 scopus 로고    scopus 로고
    • Temporal and regional patterns of axonal damage following traumatic brain injury: A beta-amyloid precursor protein immunocytochemical study in rats
    • H.M. Bramlett, S. Kraydieh, E.J. Green, and W.D. Dietrich Temporal and regional patterns of axonal damage following traumatic brain injury: a beta-amyloid precursor protein immunocytochemical study in rats J. Neuropathol. Exp. Neurol. 56 1997 1132 1141
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 1132-1141
    • Bramlett, H.M.1    Kraydieh, S.2    Green, E.J.3    Dietrich, W.D.4
  • 21
    • 0030780349 scopus 로고    scopus 로고
    • Inflammatory central nervous system demyelination: Correlation of magnetic resonance imaging findings with lesion pathology
    • W. Bruck, A. Bitsch, H. Kolenda, Y. Bruck, M. Stiefel, and H. Lassmann Inflammatory central nervous system demyelination: correlation of magnetic resonance imaging findings with lesion pathology Ann. Neurol. 42 1997 783 793
    • (1997) Ann. Neurol. , vol.42 , pp. 783-793
    • Bruck, W.1    Bitsch, A.2    Kolenda, H.3    Bruck, Y.4    Stiefel, M.5    Lassmann, H.6
  • 22
    • 0037274487 scopus 로고    scopus 로고
    • Evidence of Wallerian degeneration in normal appearing white matter in the early stages of relapsing-remitting multiple sclerosis: A HMRS study
    • B. Casanova, M.C. Martinez-Bisbal, C. Valero, B. Celda, L. Marti-Bonmati, A. Pascual, L. Landente, and F. Coret Evidence of Wallerian degeneration in normal appearing white matter in the early stages of relapsing-remitting multiple sclerosis: a HMRS study J. Neurol. 250 2003 22 28
    • (2003) J. Neurol. , vol.250 , pp. 22-28
    • Casanova, B.1    Martinez-Bisbal, M.C.2    Valero, C.3    Celda, B.4    Marti-Bonmati, L.5    Pascual, A.6    Landente, L.7    Coret, F.8
  • 23
    • 0043125609 scopus 로고    scopus 로고
    • Heme oxygenase-1 in SJL mice with experimental allergic encephalomyelitis
    • A. Chakrabarty, M.R. Emerson, and S.M. LeVine Heme oxygenase-1 in SJL mice with experimental allergic encephalomyelitis Mult. Scler. 9 2003 372 381
    • (2003) Mult. Scler. , vol.9 , pp. 372-381
    • Chakrabarty, A.1    Emerson, M.R.2    Levine, S.M.3
  • 25
    • 0028577356 scopus 로고
    • Tumor necrosis factor-alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures
    • C.C. Chao, and S. Hu Tumor necrosis factor-alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures Dev. Neurosci. 16 1994 172 179
    • (1994) Dev. Neurosci. , vol.16 , pp. 172-179
    • Chao, C.C.1    Hu, S.2
  • 26
    • 0029620390 scopus 로고
    • Interleukin-1 and tumor necrosis factor-alpha synergistically mediate neurotoxicity: Involvement of nitric oxide and of N-methyl-d-aspartate receptors
    • C.C. Chao, S. Hu, L. Ehrlich, and P.K. Peterson Interleukin-1 and tumor necrosis factor-alpha synergistically mediate neurotoxicity: involvement of nitric oxide and of N-methyl-d-aspartate receptors Brain Behav. Immun. 9 1995 355 365
    • (1995) Brain Behav. Immun. , vol.9 , pp. 355-365
    • Chao, C.C.1    Hu, S.2    Ehrlich, L.3    Peterson, P.K.4
  • 27
    • 0030108525 scopus 로고    scopus 로고
    • Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism
    • C.C. Chao, S. Hu, W.S. Sheng, D. Bu, M.I. Bukrinsky, and P.K. Peterson Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism Glia 16 1996 276 284
    • (1996) Glia , vol.16 , pp. 276-284
    • Chao, C.C.1    Hu, S.2    Sheng, W.S.3    Bu, D.4    Bukrinsky, M.I.5    Peterson, P.K.6
  • 28
    • 0000361150 scopus 로고
    • Histologie de le sclerose en plaques
    • M. Charcot Histologie de le sclerose en plaques Gazette Hopitaux 141 1868 554 558
    • (1868) Gazette Hopitaux , vol.141 , pp. 554-558
    • Charcot, M.1
  • 29
    • 0023870521 scopus 로고
    • Pharmacology of glutamate neurotoxicity in cortical cell culture: Attenuation by NMDA antagonists
    • D.W. Choi, J.Y. Koh, and S. Peters Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists J. Neurosci. 8 1988 185 196
    • (1988) J. Neurosci. , vol.8 , pp. 185-196
    • Choi, D.W.1    Koh, J.Y.2    Peters, S.3
  • 31
    • 0141566748 scopus 로고    scopus 로고
    • Temporal course of upregulation of Na(v)1.8 in Purkinje neurons parallels the progression of clinical deficit in experimental allergic encephalomyelitis
    • M.J. Craner, Y. Kataoka, A.C. Lo, J.A. Black, D. Baker, and S.G. Waxman Temporal course of upregulation of Na(v)1.8 in Purkinje neurons parallels the progression of clinical deficit in experimental allergic encephalomyelitis J. Neuropathol. Exp. Neurol. 62 2003 968 975
    • (2003) J. Neuropathol. Exp. Neurol. , vol.62 , pp. 968-975
    • Craner, M.J.1    Kataoka, Y.2    Lo, A.C.3    Black, J.A.4    Baker, D.5    Waxman, S.G.6
  • 32
    • 0037819578 scopus 로고    scopus 로고
    • Abnormal sodium channel distribution in optic nerve axons in a model of inflammatory demyelination
    • M.J. Craner, A.C. Lo, J.A. Black, and S.G. Waxman Abnormal sodium channel distribution in optic nerve axons in a model of inflammatory demyelination Brain 126 2003 1552 1561
    • (2003) Brain , vol.126 , pp. 1552-1561
    • Craner, M.J.1    Lo, A.C.2    Black, J.A.3    Waxman, S.G.4
  • 33
    • 0742305831 scopus 로고    scopus 로고
    • Co-localization of sodium channel Nav1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE
    • M.J. Craner, B.C. Hains, A.C. Lo, J.A. Black, and S.G. Waxman Co-localization of sodium channel Nav1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE Brain 127 2004 294 303
    • (2004) Brain , vol.127 , pp. 294-303
    • Craner, M.J.1    Hains, B.C.2    Lo, A.C.3    Black, J.A.4    Waxman, S.G.5
  • 34
    • 0029907622 scopus 로고    scopus 로고
    • The expression of tissue-type plasminogen activator, matrix metalloproteases and endogenous inhibitors in the central nervous system in multiple sclerosis: Comparison of stages in lesion evolution
    • M.L. Cuzner, D. Gveric, C. Strand, A.J. Loughlin, L. Paemen, G. Opdenakker, and J. Newcombe The expression of tissue-type plasminogen activator, matrix metalloproteases and endogenous inhibitors in the central nervous system in multiple sclerosis: comparison of stages in lesion evolution J. Neuropathol. Exp. Neurol. 55 1996 1194 1204
    • (1996) J. Neuropathol. Exp. Neurol. , vol.55 , pp. 1194-1204
    • Cuzner, M.L.1    Gveric, D.2    Strand, C.3    Loughlin, A.J.4    Paemen, L.5    Opdenakker, G.6    Newcombe, J.7
  • 37
    • 0029565567 scopus 로고
    • Persistent functional deficit in multiple sclerosis and autosomal dominant cerebellar ataxia is associated with axon loss
    • C.A. Davie, G.J. Barker, S. Webb, P.S. Tofts, A.J. Thompson, A.E. Harding, W.I. McDonald, and D.H. Miller Persistent functional deficit in multiple sclerosis and autosomal dominant cerebellar ataxia is associated with axon loss Brain 118 Pt. 6 1995 1583 1592
    • (1995) Brain , vol.118 , Issue.6 PART , pp. 1583-1592
    • Davie, C.A.1    Barker, G.J.2    Webb, S.3    Tofts, P.S.4    Thompson, A.J.5    Harding, A.E.6    McDonald, W.I.7    Miller, D.H.8
  • 39
    • 0030636128 scopus 로고    scopus 로고
    • Immunocytochemical characterization of the expression of inducible and constitutive isoforms of nitric oxide synthase in demyelinating multiple sclerosis lesions
    • C.J. De Groot, S.R. Ruuls, J.W. Theeuwes, C.D. Dijkstra, and P. van der Valk Immunocytochemical characterization of the expression of inducible and constitutive isoforms of nitric oxide synthase in demyelinating multiple sclerosis lesions J. Neuropathol. Exp. Neurol. 56 1997 10 20
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 10-20
    • De Groot, C.J.1    Ruuls, S.R.2    Theeuwes, J.W.3    Dijkstra, C.D.4    Van Der Valk, P.5
  • 40
    • 0034906715 scopus 로고    scopus 로고
    • Post-mortem MRI-guided sampling of multiple sclerosis brain lesions: Increased yield of active demyelinating and (p)reactive lesions
    • C.J. De Groot, E. Bergers, W. Kamphorst, R. Ravid, C.H. Polman, F. Barkhof, and P. van der Valk Post-mortem MRI-guided sampling of multiple sclerosis brain lesions: increased yield of active demyelinating and (p)reactive lesions Brain 124 2001 1635 1645
    • (2001) Brain , vol.124 , pp. 1635-1645
    • De Groot, C.J.1    Bergers, E.2    Kamphorst, W.3    Ravid, R.4    Polman, C.H.5    Barkhof, F.6    Van Der Valk, P.7
  • 41
    • 0028792005 scopus 로고
    • Reversible decreases in N-acetylaspartate after acute brain injury
    • N. De Stefano, P.M. Matthews, and D.L. Arnold Reversible decreases in N-acetylaspartate after acute brain injury Magn. Reson. Med. 34 1995 721 727
    • (1995) Magn. Reson. Med. , vol.34 , pp. 721-727
    • De Stefano, N.1    Matthews, P.M.2    Arnold, D.L.3
  • 42
    • 0032852674 scopus 로고    scopus 로고
    • In vivo evidence for axonal dysfunction remote from focal cerebral demyelination of the type seen in multiple sclerosis
    • N. De Stefano, S. Narayanan, P.M. Matthews, G.S. Francis, J.P. Antel, and D.L. Arnold In vivo evidence for axonal dysfunction remote from focal cerebral demyelination of the type seen in multiple sclerosis Brain 122 Pt. 10 1999 1933 1939
    • (1999) Brain , vol.122 , Issue.10 PART , pp. 1933-1939
    • De Stefano, N.1    Narayanan, S.2    Matthews, P.M.3    Francis, G.S.4    Antel, J.P.5    Arnold, D.L.6
  • 46
    • 0033773770 scopus 로고    scopus 로고
    • Heme oxygenase-1 and NADPH cytochrome P450 reductase expression in experimental allergic encephalomyelitis: An expanded view of the stress response
    • M.R. Emerson, and S.M. LeVine Heme oxygenase-1 and NADPH cytochrome P450 reductase expression in experimental allergic encephalomyelitis: an expanded view of the stress response J. Neurochem. 75 2000 2555 2562
    • (2000) J. Neurochem. , vol.75 , pp. 2555-2562
    • Emerson, M.R.1    Levine, S.M.2
  • 47
    • 0031773432 scopus 로고    scopus 로고
    • Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture
    • A.G. Estevez, N. Spear, S.M. Manuel, L. Barbeito, R. Radi, and J.S. Beckman Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture Prog. Brain Res. 118 1998 269 280
    • (1998) Prog. Brain Res. , vol.118 , pp. 269-280
    • Estevez, A.G.1    Spear, N.2    Manuel, S.M.3    Barbeito, L.4    Radi, R.5    Beckman, J.S.6
  • 48
    • 0033849266 scopus 로고    scopus 로고
    • Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis
    • N. Evangelou, D. Konz, M.M. Esiri, S. Smith, J. Palace, and P.M. Matthews Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis Brain 123 Pt. 9 2000 1845 1849
    • (2000) Brain , vol.123 , Issue.9 PART , pp. 1845-1849
    • Evangelou, N.1    Konz, D.2    Esiri, M.M.3    Smith, S.4    Palace, J.5    Matthews, P.M.6
  • 49
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • B. Ferguson, M.K. Matyszak, M.M. Esiri, and V.H. Perry Axonal damage in acute multiple sclerosis lesions Brain 120 Pt. 3 1997 393 399
    • (1997) Brain , vol.120 , Issue.3 PART , pp. 393-399
    • Ferguson, B.1    Matyszak, M.K.2    Esiri, M.M.3    Perry, V.H.4
  • 50
    • 0035866558 scopus 로고    scopus 로고
    • Multiple sclerosis: A white matter disease with associated gray matter damage
    • M. Filippi Multiple sclerosis: a white matter disease with associated gray matter damage J. Neurol. Sci. 185 2001 3 4
    • (2001) J. Neurol. Sci. , vol.185 , pp. 3-4
    • Filippi, M.1
  • 51
    • 0029943301 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia
    • S.M. Fine, R.A. Angel, S.W. Perry, L.G. Epstein, J.D. Rothstein, S. Dewhurst, and H.A. Gelbard Tumor necrosis factor alpha inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia J. Biol. Chem. 271 1996 15303 15306
    • (1996) J. Biol. Chem. , vol.271 , pp. 15303-15306
    • Fine, S.M.1    Angel, R.A.2    Perry, S.W.3    Epstein, L.G.4    Rothstein, J.D.5    Dewhurst, S.6    Gelbard, H.A.7
  • 52
    • 0030860260 scopus 로고    scopus 로고
    • Soluble macrophage factors trigger apoptosis in cultured hippocampal neurons
    • M.P. Flavin, K. Coughlin, and L.T. Ho Soluble macrophage factors trigger apoptosis in cultured hippocampal neurons Neuroscience 80 1997 437 448
    • (1997) Neuroscience , vol.80 , pp. 437-448
    • Flavin, M.P.1    Coughlin, K.2    Ho, L.T.3
  • 53
    • 0034652701 scopus 로고    scopus 로고
    • Microglial tissue plasminogen activator (tPA) triggers neuronal apoptosis in vitro
    • M.P. Flavin, G. Zhao, and L.T. Ho Microglial tissue plasminogen activator (tPA) triggers neuronal apoptosis in vitro Glia 29 2000 347 354
    • (2000) Glia , vol.29 , pp. 347-354
    • Flavin, M.P.1    Zhao, G.2    Ho, L.T.3
  • 55
    • 0019160539 scopus 로고
    • Reorganization of the axon membrane in demyelinated peripheral nerve fibers: Morphological evidence
    • R.E. Foster, C.C. Whalen, and S.G. Waxman Reorganization of the axon membrane in demyelinated peripheral nerve fibers: morphological evidence Science 210 1980 661 663
    • (1980) Science , vol.210 , pp. 661-663
    • Foster, R.E.1    Whalen, C.C.2    Waxman, S.G.3
  • 57
    • 0030964023 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6)-a molecule with both beneficial and destructive potentials
    • R.A. Gadient, and U.H. Otten Interleukin-6 (IL-6)-a molecule with both beneficial and destructive potentials Prog. Neurobiol. 52 1997 379 390
    • (1997) Prog. Neurobiol. , vol.52 , pp. 379-390
    • Gadient, R.A.1    Otten, U.H.2
  • 58
    • 0036143998 scopus 로고    scopus 로고
    • Soluble guanylyl cyclase activator YC-1 protects white matter axons from nitric oxide toxicity and metabolic stress, probably through Na(+) channel inhibition
    • G. Garthwaite, D.A. Goodwin, S. Neale, D. Riddall, and J. Garthwaite Soluble guanylyl cyclase activator YC-1 protects white matter axons from nitric oxide toxicity and metabolic stress, probably through Na(+) channel inhibition Mol. Pharmacol. 61 2002 97 104
    • (2002) Mol. Pharmacol. , vol.61 , pp. 97-104
    • Garthwaite, G.1    Goodwin, D.A.2    Neale, S.3    Riddall, D.4    Garthwaite, J.5
  • 59
    • 0027482350 scopus 로고
    • Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury
    • S.M. Gentleman, M.J. Nash, C.J. Sweeting, D.I. Graham, and G.W. Roberts Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury Neurosci. Lett. 160 1993 139 144
    • (1993) Neurosci. Lett. , vol.160 , pp. 139-144
    • Gentleman, S.M.1    Nash, M.J.2    Sweeting, C.J.3    Graham, D.I.4    Roberts, G.W.5
  • 60
    • 0042266373 scopus 로고    scopus 로고
    • Altered expression patterns of group I and II metabotropic glutamate receptors in multiple sclerosis
    • J.J. Geurts, G. Wolswijk, L. Bo, P. van der Valk, C.H. Polman, D. Troost, and E. Aronica Altered expression patterns of group I and II metabotropic glutamate receptors in multiple sclerosis Brain 126 2003 1755 1766
    • (2003) Brain , vol.126 , pp. 1755-1766
    • Geurts, J.J.1    Wolswijk, G.2    Bo, L.3    Van Der Valk, P.4    Polman, C.H.5    Troost, D.6    Aronica, E.7
  • 61
    • 0035719745 scopus 로고    scopus 로고
    • Tumor necrosis factor and motoneuronal degeneration: An open problem
    • P. Ghezzi, and T. Mennini Tumor necrosis factor and motoneuronal degeneration: an open problem Neuroimmunomodulation 9 2001 178 182
    • (2001) Neuroimmunomodulation , vol.9 , pp. 178-182
    • Ghezzi, P.1    Mennini, T.2
  • 62
    • 0027368518 scopus 로고
    • Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein
    • K. Gijbels, P. Proost, S. Masure, H. Carton, A. Billiau, and G. Opdenakker Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein J. Neurosci. Res. 36 1993 432 440
    • (1993) J. Neurosci. Res. , vol.36 , pp. 432-440
    • Gijbels, K.1    Proost, P.2    Masure, S.3    Carton, H.4    Billiau, A.5    Opdenakker, G.6
  • 63
    • 0141861944 scopus 로고    scopus 로고
    • Riluzole suppresses experimental autoimmune encephalomyelitis: Implications for the treatment of multiple sclerosis
    • Y. Gilgun-Sherki, H. Panet, E. Melamed, and D. Offen Riluzole suppresses experimental autoimmune encephalomyelitis: implications for the treatment of multiple sclerosis Brain Res. 989 2003 196 204
    • (2003) Brain Res. , vol.989 , pp. 196-204
    • Gilgun-Sherki, Y.1    Panet, H.2    Melamed, E.3    Offen, D.4
  • 64
    • 1642264093 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathogenesis of multiple sclerosis: The need for effective antioxidant therapy
    • Y. Gilgun-Sherki, E. Melamed, and D. Offen The role of oxidative stress in the pathogenesis of multiple sclerosis: the need for effective antioxidant therapy J. Neurol. 251 2004 261 268
    • (2004) J. Neurol. , vol.251 , pp. 261-268
    • Gilgun-Sherki, Y.1    Melamed, E.2    Offen, D.3
  • 65
    • 0033917384 scopus 로고    scopus 로고
    • Axonal damage induced by invading T cells in organotypic central nervous system tissue in vitro: Involvement of microglial cells
    • U. Gimsa, S.V. Peter, K. Lehmann, I. Bechmann, and R. Nitsch Axonal damage induced by invading T cells in organotypic central nervous system tissue in vitro: involvement of microglial cells Brain Pathol. 10 2000 365 377
    • (2000) Brain Pathol. , vol.10 , pp. 365-377
    • Gimsa, U.1    Peter, S.V.2    Lehmann, K.3    Bechmann, I.4    Nitsch, R.5
  • 66
    • 0031910336 scopus 로고    scopus 로고
    • Cerebrospinal fluid and serum nitric oxide metabolites in patients with multiple sclerosis
    • G. Giovannoni Cerebrospinal fluid and serum nitric oxide metabolites in patients with multiple sclerosis Mult. Scler. 4 1998 27 30
    • (1998) Mult. Scler. , vol.4 , pp. 27-30
    • Giovannoni, G.1
  • 67
    • 0027377147 scopus 로고
    • Increased generation of superoxide radicals in the blood of MS patients
    • A. Glabinski, N.S. Tawsek, and G. Bartosz Increased generation of superoxide radicals in the blood of MS patients Acta Neurol. Scand. 88 1993 174 177
    • (1993) Acta Neurol. Scand. , vol.88 , pp. 174-177
    • Glabinski, A.1    Tawsek, N.S.2    Bartosz, G.3
  • 68
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • S. Gordon Alternative activation of macrophages Nat. Rev., Immunol. 3 2003 23 35
    • (2003) Nat. Rev., Immunol. , vol.3 , pp. 23-35
    • Gordon, S.1
  • 69
    • 0000905255 scopus 로고
    • Observations on the histopathology of the cerebral lesions in disseminated sclerosis
    • J.G. Greenfield, and L.S. King Observations on the histopathology of the cerebral lesions in disseminated sclerosis. Brain 59 1936 445 458
    • (1936) Brain , vol.59 , pp. 445-458
    • Greenfield, J.G.1    King, L.S.2
  • 71
    • 0031301027 scopus 로고    scopus 로고
    • Physiological and pathological roles of interleukin-6 in the central nervous system
    • D.L. Gruol, and T.E. Nelson Physiological and pathological roles of interleukin-6 in the central nervous system Mol. Neurobiol. 15 1997 307 339
    • (1997) Mol. Neurobiol. , vol.15 , pp. 307-339
    • Gruol, D.L.1    Nelson, T.E.2
  • 72
    • 0034774402 scopus 로고    scopus 로고
    • Plasminogen activators in multiple sclerosis lesions: Implications for the inflammatory response and axonal damage
    • D. Gveric, R. Hanemaaijer, J. Newcombe, N.A. van Lent, C.F. Sier, and M.L. Cuzner Plasminogen activators in multiple sclerosis lesions: implications for the inflammatory response and axonal damage Brain 124 2001 1978 1988
    • (2001) Brain , vol.124 , pp. 1978-1988
    • Gveric, D.1    Hanemaaijer, R.2    Newcombe, J.3    Van Lent, N.A.4    Sier, C.F.5    Cuzner, M.L.6
  • 73
    • 0031148953 scopus 로고    scopus 로고
    • Glutamate metabolism is down-regulated in astrocytes during experimental allergic encephalomyelitis
    • H. Hardin-Pouzet, M. Krakowski, L. Bourbonniere, M. Didier-Bazes, E. Tran, and T. Owens Glutamate metabolism is down-regulated in astrocytes during experimental allergic encephalomyelitis Glia 20 1997 79 85
    • (1997) Glia , vol.20 , pp. 79-85
    • Hardin-Pouzet, H.1    Krakowski, M.2    Bourbonniere, L.3    Didier-Bazes, M.4    Tran, E.5    Owens, T.6
  • 74
    • 0023950687 scopus 로고
    • Suppression of experimental autoimmune neuritis by the oxygen radical scavengers superoxide dismutase and catalase
    • H.P. Hartung, B. Schafer, K. Heininger, and K.V. Toyka Suppression of experimental autoimmune neuritis by the oxygen radical scavengers superoxide dismutase and catalase Ann. Neurol. 23 1988 453 460
    • (1988) Ann. Neurol. , vol.23 , pp. 453-460
    • Hartung, H.P.1    Schafer, B.2    Heininger, K.3    Toyka, K.V.4
  • 75
    • 0022459287 scopus 로고
    • Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions
    • S.L. Hauser, A.K. Bhan, F. Gilles, M. Kemp, C. Kerr, and H.L. Weiner Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions Ann. Neurol. 19 1986 578 587
    • (1986) Ann. Neurol. , vol.19 , pp. 578-587
    • Hauser, S.L.1    Bhan, A.K.2    Gilles, F.3    Kemp, M.4    Kerr, C.5    Weiner, H.L.6
  • 76
    • 0036295559 scopus 로고    scopus 로고
    • Activated microglia (BV-2) facilitation of TNF-alpha-mediated motor neuron death in vitro
    • B.P. He, W. Wen, and M.J. Strong Activated microglia (BV-2) facilitation of TNF-alpha-mediated motor neuron death in vitro J. Neuroimmunol. 128 2002 31 38
    • (2002) J. Neuroimmunol. , vol.128 , pp. 31-38
    • He, B.P.1    Wen, W.2    Strong, M.J.3
  • 79
    • 0029835160 scopus 로고    scopus 로고
    • Myelin-stimulated macrophages release neurotrophic factors for adult dorsal root ganglion neurons in culture
    • N. Hikawa, and T. Takenaka Myelin-stimulated macrophages release neurotrophic factors for adult dorsal root ganglion neurons in culture Cell Mol. Neurobiol. 16 1996 517 528
    • (1996) Cell Mol. Neurobiol. , vol.16 , pp. 517-528
    • Hikawa, N.1    Takenaka, T.2
  • 80
    • 0002213362 scopus 로고    scopus 로고
    • Glutamate in health and disease: The role of inhibitors
    • P.R. Bär L. Flint Beal Marcel Dekker Inc New York
    • W.F. Holt Glutamate in health and disease: the role of inhibitors P.R. Bär L. Flint Beal Neuroprotection in CNS Diseases 1997 Marcel Dekker Inc New York 87 119
    • (1997) Neuroprotection in CNS Diseases , pp. 87-119
    • Holt, W.F.1
  • 82
    • 0034038044 scopus 로고    scopus 로고
    • Uric acid, a peroxynitrite scavenger, inhibits CNS inflammation, blood-CNS barrier permeability changes, and tissue damage in a mouse model of multiple sclerosis
    • D.C. Hooper, G.S. Scott, A. Zborek, T. Mikheeva, R.B. Kean, H. Koprowski, and S.V. Spitsin Uric acid, a peroxynitrite scavenger, inhibits CNS inflammation, blood-CNS barrier permeability changes, and tissue damage in a mouse model of multiple sclerosis FASEB J. 14 2000 691 698
    • (2000) FASEB J. , vol.14 , pp. 691-698
    • Hooper, D.C.1    Scott, G.S.2    Zborek, A.3    Mikheeva, T.4    Kean, R.B.5    Koprowski, H.6    Spitsin, S.V.7
  • 83
    • 0025015655 scopus 로고
    • Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages
    • I. Huitinga, N. van Rooijen, C.J. De Groot, B.M. Uitdehaag, and C.D. Dijkstra Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages J. Exp. Med. 172 1990 1025 1033
    • (1990) J. Exp. Med. , vol.172 , pp. 1025-1033
    • Huitinga, I.1    Van Rooijen, N.2    De Groot, C.J.3    Uitdehaag, B.M.4    Dijkstra, C.D.5
  • 84
    • 0022372317 scopus 로고
    • Lipid peroxidation products and antioxidant proteins in plasma and cerebrospinal fluid from multiple sclerosis patients
    • M.I. Hunter, B.C. Nlemadim, and D.L. Davidson Lipid peroxidation products and antioxidant proteins in plasma and cerebrospinal fluid from multiple sclerosis patients Neurochem. Res. 10 1985 1645 1652
    • (1985) Neurochem. Res. , vol.10 , pp. 1645-1652
    • Hunter, M.I.1    Nlemadim, B.C.2    Davidson, D.L.3
  • 85
    • 0032077890 scopus 로고    scopus 로고
    • Synergistic neurotoxic effects of combined treatments with cytokines in murine primary mixed neuron/glia cultures
    • G.H. Jeohn, L.Y. Kong, B. Wilson, P. Hudson, and J.S. Hong Synergistic neurotoxic effects of combined treatments with cytokines in murine primary mixed neuron/glia cultures J. Neuroimmunol. 85 1998 1 10
    • (1998) J. Neuroimmunol. , vol.85 , pp. 1-10
    • Jeohn, G.H.1    Kong, L.Y.2    Wilson, B.3    Hudson, P.4    Hong, J.S.5
  • 86
    • 0037309442 scopus 로고    scopus 로고
    • Blockers of sodium and calcium entry protect axons from nitric oxide-mediated degeneration
    • R. Kapoor, M. Davies, P.A. Blaker, S.M. Hall, and K.J. Smith Blockers of sodium and calcium entry protect axons from nitric oxide-mediated degeneration Ann. Neurol. 53 2003 174 180
    • (2003) Ann. Neurol. , vol.53 , pp. 174-180
    • Kapoor, R.1    Davies, M.2    Blaker, P.A.3    Hall, S.M.4    Smith, K.J.5
  • 87
    • 0034548047 scopus 로고    scopus 로고
    • The peroxynitrite scavenger uric acid prevents inflammatory cell invasion into the central nervous system in experimental allergic encephalomyelitis through maintenance of blood-central nervous system barrier integrity
    • R.B. Kean, S.V. Spitsin, T. Mikheeva, G.S. Scott, and D.C. Hooper The peroxynitrite scavenger uric acid prevents inflammatory cell invasion into the central nervous system in experimental allergic encephalomyelitis through maintenance of blood-central nervous system barrier integrity J. Immunol. 165 2000 6511 6518
    • (2000) J. Immunol. , vol.165 , pp. 6511-6518
    • Kean, R.B.1    Spitsin, S.V.2    Mikheeva, T.3    Scott, G.S.4    Hooper, D.C.5
  • 90
    • 0033870097 scopus 로고    scopus 로고
    • Multiple sclerosis and chronic autoimmune encephalomyelitis: A comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions
    • B. Kornek, M.K. Storch, R. Weissert, E. Wallstroem, A. Stefferl, T. Olsson, C. Linington, M. Schmidbauer, and H. Lassmann Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions Am. J. Pathol. 157 2000 267 276
    • (2000) Am. J. Pathol. , vol.157 , pp. 267-276
    • Kornek, B.1    Storch, M.K.2    Weissert, R.3    Wallstroem, E.4    Stefferl, A.5    Olsson, T.6    Linington, C.7    Schmidbauer, M.8    Lassmann, H.9
  • 93
    • 0025731835 scopus 로고
    • Nitric oxide: An endogenous modulator of leukocyte adhesion
    • P. Kubes, M. Suzuki, and D.N. Granger Nitric oxide: an endogenous modulator of leukocyte adhesion Proc. Natl. Acad. Sci. U. S. A 88 1991 4651 4655
    • (1991) Proc. Natl. Acad. Sci. U. S. a , vol.88 , pp. 4651-4655
    • Kubes, P.1    Suzuki, M.2    Granger, D.N.3
  • 94
    • 0036788406 scopus 로고    scopus 로고
    • Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time
    • T. Kuhlmann, G. Lingfeld, A. Bitsch, J. Schuchardt, and W. Bruck Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time Brain 125 2002 2202 2212
    • (2002) Brain , vol.125 , pp. 2202-2212
    • Kuhlmann, T.1    Lingfeld, G.2    Bitsch, A.3    Schuchardt, J.4    Bruck, W.5
  • 95
    • 0034749944 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis
    • D. Leppert, R.L. Lindberg, L. Kappos, and S.L. Leib Matrix metalloproteinases: multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis Brain Res. Brain Res. Rev. 36 2001 249 257
    • (2001) Brain Res. Brain Res. Rev. , vol.36 , pp. 249-257
    • Leppert, D.1    Lindberg, R.L.2    Kappos, L.3    Leib, S.L.4
  • 96
    • 0034143360 scopus 로고    scopus 로고
    • Mechanisms of ionotropic glutamate receptor-mediated excitotoxicity in isolated spinal cord white matter
    • S. Li, and P.K. Stys Mechanisms of ionotropic glutamate receptor-mediated excitotoxicity in isolated spinal cord white matter J. Neurosci. 20 2000 1190 1198
    • (2000) J. Neurosci. , vol.20 , pp. 1190-1198
    • Li, S.1    Stys, P.K.2
  • 97
    • 0029132999 scopus 로고
    • Changes of beta-amyloid precursor protein after compression trauma to the spinal cord: An experimental study in the rat using immunohistochemistry
    • G.L. Li, M. Farooque, A. Holtz, and Y. Olsson Changes of beta-amyloid precursor protein after compression trauma to the spinal cord: an experimental study in the rat using immunohistochemistry J. Neurotrauma 12 1995 269 277
    • (1995) J. Neurotrauma , vol.12 , pp. 269-277
    • Li, G.L.1    Farooque, M.2    Holtz, A.3    Olsson, Y.4
  • 98
    • 0034842248 scopus 로고    scopus 로고
    • The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosis
    • R.L. Lindberg, C.J. De Groot, L. Montagne, P. Freitag, P. van der Valk, L. Kappos, and D. Leppert The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosis Brain 124 2001 1743 1753
    • (2001) Brain , vol.124 , pp. 1743-1753
    • Lindberg, R.L.1    De Groot, C.J.2    Montagne, L.3    Freitag, P.4    Van Der Valk, P.5    Kappos, L.6    Leppert, D.7
  • 99
    • 0037532741 scopus 로고    scopus 로고
    • Bilirubin as a potent antioxidant suppresses experimental autoimmune encephalomyelitis: Implications for the role of oxidative stress in the development of multiple sclerosis
    • Y. Liu, B. Zhu, X. Wang, L. Luo, P. Li, D.W. Paty, and M.S. Cynader Bilirubin as a potent antioxidant suppresses experimental autoimmune encephalomyelitis: implications for the role of oxidative stress in the development of multiple sclerosis J. Neuroimmunol. 139 2003 27 35
    • (2003) J. Neuroimmunol. , vol.139 , pp. 27-35
    • Liu, Y.1    Zhu, B.2    Wang, X.3    Luo, L.4    Li, P.5    Paty, D.W.6    Cynader, M.S.7
  • 100
    • 0030072651 scopus 로고    scopus 로고
    • Clinical and magnetic resonance imaging predictors of disability in primary and secondary progressive multiple sclerosis
    • N.A. Losseff, D.P. Kingsley, W.I. McDonald, D.H. Miller, and A.J. Thompson Clinical and magnetic resonance imaging predictors of disability in primary and secondary progressive multiple sclerosis Mult. Scler. 1 1996 218 222
    • (1996) Mult. Scler. , vol.1 , pp. 218-222
    • Losseff, N.A.1    Kingsley, D.P.2    McDonald, W.I.3    Miller, D.H.4    Thompson, A.J.5
  • 101
    • 0034662806 scopus 로고    scopus 로고
    • Oxidative damage to mitochondrial DNA and activity of mitochondrial enzymes in chronic active lesions of multiple sclerosis
    • F. Lu, M. Selak, J. OConnor, S. Croul, C. Lorenzana, C. Butunoi, and B. Kalman Oxidative damage to mitochondrial DNA and activity of mitochondrial enzymes in chronic active lesions of multiple sclerosis J. Neurol. Sci. 177 2000 95 103
    • (2000) J. Neurol. Sci. , vol.177 , pp. 95-103
    • Lu, F.1    Selak, M.2    Oconnor, J.3    Croul, S.4    Lorenzana, C.5    Butunoi, C.6    Kalman, B.7
  • 102
    • 0037115099 scopus 로고    scopus 로고
    • Involvement of tissue plasminogen activator in onset and effector phases of experimental allergic encephalomyelitis
    • W. Lu, M. Bhasin, and S.E. Tsirka Involvement of tissue plasminogen activator in onset and effector phases of experimental allergic encephalomyelitis J. Neurosci. 22 2002 10781 10789
    • (2002) J. Neurosci. , vol.22 , pp. 10781-10789
    • Lu, W.1    Bhasin, M.2    Tsirka, S.E.3
  • 103
    • 0026751291 scopus 로고
    • Elevated secretion of reactive nitrogen and oxygen intermediates by inflammatory leukocytes in hyperacute experimental autoimmune encephalomyelitis: Enhancement by the soluble products of encephalitogenic T cells
    • J.D. MacMicking, D.O. Willenborg, M.J. Weidemann, K.A. Rockett, and W.B. Cowden Elevated secretion of reactive nitrogen and oxygen intermediates by inflammatory leukocytes in hyperacute experimental autoimmune encephalomyelitis: enhancement by the soluble products of encephalitogenic T cells J. Exp. Med. 176 1992 303 307
    • (1992) J. Exp. Med. , vol.176 , pp. 303-307
    • MacMicking, J.D.1    Willenborg, D.O.2    Weidemann, M.J.3    Rockett, K.A.4    Cowden, W.B.5
  • 105
    • 0346996608 scopus 로고    scopus 로고
    • Tumor-associated macrophages and dendritic cells as prototypic type II polarized myeloid populations
    • A. Mantovani, T. Schioppa, S.K. Biswas, F. Marchesi, P. Allavena, and A. Sica Tumor-associated macrophages and dendritic cells as prototypic type II polarized myeloid populations Tumori 89 2003 459 468
    • (2003) Tumori , vol.89 , pp. 459-468
    • Mantovani, A.1    Schioppa, T.2    Biswas, S.K.3    Marchesi, F.4    Allavena, P.5    Sica, A.6
  • 106
    • 0036790853 scopus 로고    scopus 로고
    • Alpha lipoic acid inhibits T cell migration into the spinal cord and suppresses and treats experimental autoimmune encephalomyelitis
    • G.H. Marracci, R.E. Jones, G.P. McKeon, and D.N. Bourdette Alpha lipoic acid inhibits T cell migration into the spinal cord and suppresses and treats experimental autoimmune encephalomyelitis J. Neuroimmunol. 131 2002 104 114
    • (2002) J. Neuroimmunol. , vol.131 , pp. 104-114
    • Marracci, G.H.1    Jones, R.E.2    McKeon, G.P.3    Bourdette, D.N.4
  • 107
    • 0029943953 scopus 로고    scopus 로고
    • Assessment of lesion pathology in multiple sclerosis using quantitative MRI morphometry and magnetic resonance spectroscopy
    • P.M. Matthews, E. Pioro, S. Narayanan, N. De Stefano, L. Fu, G. Francis, J. Antel, C. Wolfson, and D.L. Arnold Assessment of lesion pathology in multiple sclerosis using quantitative MRI morphometry and magnetic resonance spectroscopy Brain 119 Pt. 3 1996 715 722
    • (1996) Brain , vol.119 , Issue.3 PART , pp. 715-722
    • Matthews, P.M.1    Pioro, E.2    Narayanan, S.3    De Stefano, N.4    Fu, L.5    Francis, G.6    Antel, J.7    Wolfson, C.8    Arnold, D.L.9
  • 110
    • 0031952612 scopus 로고    scopus 로고
    • Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity
    • J.W. McDonald, S.P. Althomsons, K.L. Hyrc, D.W. Choi, and M.P. Goldberg Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity Nat. Med. 4 1998 291 297
    • (1998) Nat. Med. , vol.4 , pp. 291-297
    • McDonald, J.W.1    Althomsons, S.P.2    Hyrc, K.L.3    Choi, D.W.4    Goldberg, M.P.5
  • 111
    • 0034529401 scopus 로고    scopus 로고
    • MHC class I-restricted killing of neurons by virus-specific CD8+ T lymphocytes is effected through the Fas/FasL, but not the perforin pathway
    • I.M. Medana, A. Gallimore, A. Oxenius, M.M. Martinic, H. Wekerle, and H. Neumann MHC class I-restricted killing of neurons by virus-specific CD8+ T lymphocytes is effected through the Fas/FasL, but not the perforin pathway Eur. J. Immunol. 30 2000 3623 3633
    • (2000) Eur. J. Immunol. , vol.30 , pp. 3623-3633
    • Medana, I.M.1    Gallimore, A.2    Oxenius, A.3    Martinic, M.M.4    Wekerle, H.5    Neumann, H.6
  • 112
    • 0028181805 scopus 로고
    • Dibutyryl cAMP, interleukin-1 beta, and macrophage conditioned medium enhance the ability of astrocytes to promote neurite growth
    • C. Miller, O. Tsatas, and S. David Dibutyryl cAMP, interleukin-1 beta, and macrophage conditioned medium enhance the ability of astrocytes to promote neurite growth J. Neurosci. Res. 38 1994 56 63
    • (1994) J. Neurosci. Res. , vol.38 , pp. 56-63
    • Miller, C.1    Tsatas, O.2    David, S.3
  • 113
    • 0344157469 scopus 로고    scopus 로고
    • The role of tumour necrosis factor, interleukin 6, interferon-gamma and inducible nitric oxide synthase in the development and pathology of the nervous system
    • M.A. Munoz-Fernandez, and M. Fresno The role of tumour necrosis factor, interleukin 6, interferon-gamma and inducible nitric oxide synthase in the development and pathology of the nervous system Prog. Neurobiol. 56 1998 307 340
    • (1998) Prog. Neurobiol. , vol.56 , pp. 307-340
    • Munoz-Fernandez, M.A.1    Fresno, M.2
  • 115
    • 0027068020 scopus 로고
    • Studies of lipid peroxidation products in cerebrospinal fluid and serum in multiple sclerosis and other conditions
    • R. Naidoo, and M.L. Knapp Studies of lipid peroxidation products in cerebrospinal fluid and serum in multiple sclerosis and other conditions Clin. Chem. 38 1992 2449 2454
    • (1992) Clin. Chem. , vol.38 , pp. 2449-2454
    • Naidoo, R.1    Knapp, M.L.2
  • 116
    • 0033965231 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3 treatment decreases macrophage accumulation in the CNS of mice with experimental autoimmune encephalomyelitis
    • F.E. Nashold, D.J. Miller, and C.E. Hayes 1,25-dihydroxyvitamin D3 treatment decreases macrophage accumulation in the CNS of mice with experimental autoimmune encephalomyelitis J. Neuroimmunol. 103 2000 171 179
    • (2000) J. Neuroimmunol. , vol.103 , pp. 171-179
    • Nashold, F.E.1    Miller, D.J.2    Hayes, C.E.3
  • 117
    • 0033624426 scopus 로고    scopus 로고
    • The immunological microenvironment in the CNS: Implications on neuronal cell death and survival
    • H. Neumann The immunological microenvironment in the CNS: implications on neuronal cell death and survival J. Neural Transm., Suppl. 59 2000 59 68
    • (2000) J. Neural Transm., Suppl. , vol.59 , pp. 59-68
    • Neumann, H.1
  • 118
  • 119
    • 0031054508 scopus 로고    scopus 로고
    • Major histocompatibility complex (MHC) class I gene expression in single neurons of the central nervous system: Differential regulation by interferon (IFN)-gamma and tumor necrosis factor (TNF)-alpha
    • H. Neumann, H. Schmidt, A. Cavalie, D. Jenne, and H. Wekerle Major histocompatibility complex (MHC) class I gene expression in single neurons of the central nervous system: differential regulation by interferon (IFN)-gamma and tumor necrosis factor (TNF)-alpha J. Exp. Med. 185 1997 305 316
    • (1997) J. Exp. Med. , vol.185 , pp. 305-316
    • Neumann, H.1    Schmidt, H.2    Cavalie, A.3    Jenne, D.4    Wekerle, H.5
  • 120
    • 0021972753 scopus 로고
    • Serum antibodies against central nervous system proteins in human demyelinating disease
    • J. Newcombe, S. Gahan, and M.L. Cuzner Serum antibodies against central nervous system proteins in human demyelinating disease Clin. Exp. Immunol. 59 1985 383 390
    • (1985) Clin. Exp. Immunol. , vol.59 , pp. 383-390
    • Newcombe, J.1    Gahan, S.2    Cuzner, M.L.3
  • 121
    • 0035170589 scopus 로고    scopus 로고
    • T-cell- and macrophage-mediated axon damage in the absence of a CNS-specific immune response: Involvement of metalloproteinases
    • T.A. Newman, S.T. Woolley, P.M. Hughes, N.R. Sibson, D.C. Anthony, and V.H. Perry T-cell- and macrophage-mediated axon damage in the absence of a CNS-specific immune response: involvement of metalloproteinases Brain 124 2001 2203 2214
    • (2001) Brain , vol.124 , pp. 2203-2214
    • Newman, T.A.1    Woolley, S.T.2    Hughes, P.M.3    Sibson, N.R.4    Anthony, D.C.5    Perry, V.H.6
  • 122
    • 0037312562 scopus 로고    scopus 로고
    • Regulation of gene expression in experimental autoimmune encephalomyelitis indicates early neuronal dysfunction
    • A. Nicot, P.V. Ratnakar, Y. Ron, C.C. Chen, and S. Elkabes Regulation of gene expression in experimental autoimmune encephalomyelitis indicates early neuronal dysfunction Brain 126 2003 398 412
    • (2003) Brain , vol.126 , pp. 398-412
    • Nicot, A.1    Ratnakar, P.V.2    Ron, Y.3    Chen, C.C.4    Elkabes, S.5
  • 124
    • 0035889960 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthase initiates relapsing remitting experimental autoimmune encephalomyelitis in rats, yet nitric oxide appears to be essential for clinical expression of disease
    • N.C. OBrien, B. Charlton, W.B. Cowden, and D.O. Willenborg Inhibition of nitric oxide synthase initiates relapsing remitting experimental autoimmune encephalomyelitis in rats, yet nitric oxide appears to be essential for clinical expression of disease J. Immunol. 167 2001 5904 5912
    • (2001) J. Immunol. , vol.167 , pp. 5904-5912
    • Obrien, N.C.1    Charlton, B.2    Cowden, W.B.3    Willenborg, D.O.4
  • 126
    • 0027468201 scopus 로고
    • Vulnerability of oligodendroglia to glutamate: Pharmacology, mechanisms, and prevention
    • A. Oka, M.J. Belliveau, P.A. Rosenberg, and J.J. Volpe Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms, and prevention J. Neurosci. 13 1993 1441 1453
    • (1993) J. Neurosci. , vol.13 , pp. 1441-1453
    • Oka, A.1    Belliveau, M.J.2    Rosenberg, P.A.3    Volpe, J.J.4
  • 127
    • 0031859370 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase and nitrotyrosine are found in monocytes/macrophages and/or astrocytes in acute, but not in chronic, multiple sclerosis
    • E.L. Oleszak, E. Zaczynska, M. Bhattacharjee, C. Butunoi, A. Legido, and C.D. Katsetos Inducible nitric oxide synthase and nitrotyrosine are found in monocytes/macrophages and/or astrocytes in acute, but not in chronic, multiple sclerosis Clin. Diagn. Lab. Immunol. 5 1998 438 445
    • (1998) Clin. Diagn. Lab. Immunol. , vol.5 , pp. 438-445
    • Oleszak, E.L.1    Zaczynska, E.2    Bhattacharjee, M.3    Butunoi, C.4    Legido, A.5    Katsetos, C.D.6
  • 128
    • 0033249811 scopus 로고    scopus 로고
    • Elevated plasma level of plasminogen activator inhibitor-1 (PAI-1) in patients with relapsing-remitting multiple sclerosis
    • H. Onodera, I. Nakashima, K. Fujihara, T. Nagata, and Y. Itoyama Elevated plasma level of plasminogen activator inhibitor-1 (PAI-1) in patients with relapsing-remitting multiple sclerosis Tohoku J. Exp. Med. 189 1999 259 265
    • (1999) Tohoku J. Exp. Med. , vol.189 , pp. 259-265
    • Onodera, H.1    Nakashima, I.2    Fujihara, K.3    Nagata, T.4    Itoyama, Y.5
  • 130
    • 0030948467 scopus 로고    scopus 로고
    • The role of nitric oxide in multiple sclerosis
    • J.F. Parkinson, B. Mitrovic, and J.E. Merrill The role of nitric oxide in multiple sclerosis J. Mol. Med. 75 1997 174 186
    • (1997) J. Mol. Med. , vol.75 , pp. 174-186
    • Parkinson, J.F.1    Mitrovic, B.2    Merrill, J.E.3
  • 131
    • 0023114078 scopus 로고
    • Demyelination and neurological signs in experimental allergic encephalomyelitis
    • M.P. Pender Demyelination and neurological signs in experimental allergic encephalomyelitis J. Neuroimmunol. 15 1987 11 24
    • (1987) J. Neuroimmunol. , vol.15 , pp. 11-24
    • Pender, M.P.1
  • 132
    • 0037911433 scopus 로고    scopus 로고
    • Treatment with metallothionein prevents demyelination and axonal damage and increases oligodendrocyte precursors and tissue repair during experimental autoimmune encephalomyelitis
    • M. Penkowa, and J. Hidalgo Treatment with metallothionein prevents demyelination and axonal damage and increases oligodendrocyte precursors and tissue repair during experimental autoimmune encephalomyelitis J. Neurosci. Res. 72 2003 574 586
    • (2003) J. Neurosci. Res. , vol.72 , pp. 574-586
    • Penkowa, M.1    Hidalgo, J.2
  • 133
    • 0035479008 scopus 로고    scopus 로고
    • Altered inflammatory response and increased neurodegeneration in metallothionein I+II deficient mice during experimental autoimmune encephalomyelitis
    • M. Penkowa, C. Espejo, E.M. Martinez-Caceres, C.B. Poulsen, X. Montalban, and J. Hidalgo Altered inflammatory response and increased neurodegeneration in metallothionein I+II deficient mice during experimental autoimmune encephalomyelitis J. Neuroimmunol. 119 2001 248 260
    • (2001) J. Neuroimmunol. , vol.119 , pp. 248-260
    • Penkowa, M.1    Espejo, C.2    Martinez-Caceres, E.M.3    Poulsen, C.B.4    Montalban, X.5    Hidalgo, J.6
  • 134
    • 0028297676 scopus 로고
    • Involvement of the cystine transport system xc- in the macrophage-induced glutamate-dependent cytotoxicity to neurons
    • D. Piani, and A. Fontana Involvement of the cystine transport system xc- in the macrophage-induced glutamate-dependent cytotoxicity to neurons J. Immunol. 152 1994 3578 3585
    • (1994) J. Immunol. , vol.152 , pp. 3578-3585
    • Piani, D.1    Fontana, A.2
  • 135
    • 0025720505 scopus 로고
    • Murine brain macrophages induced NMDA receptor mediated neurotoxicity in vitro by secreting glutamate
    • D. Piani, K. Frei, K.Q. Do, M. Cuenod, and A. Fontana Murine brain macrophages induced NMDA receptor mediated neurotoxicity in vitro by secreting glutamate Neurosci. Lett. 133 1991 159 162
    • (1991) Neurosci. Lett. , vol.133 , pp. 159-162
    • Piani, D.1    Frei, K.2    Do, K.Q.3    Cuenod, M.4    Fontana, A.5
  • 136
    • 0027369531 scopus 로고
    • Glutamate uptake by astrocytes is inhibited by reactive oxygen intermediates but not by other macrophage-derived molecules including cytokines, leukotrienes or platelet-activating factor
    • D. Piani, K. Frei, H.W. Pfister, and A. Fontana Glutamate uptake by astrocytes is inhibited by reactive oxygen intermediates but not by other macrophage-derived molecules including cytokines, leukotrienes or platelet-activating factor J. Neuroimmunol. 48 1993 99 104
    • (1993) J. Neuroimmunol. , vol.48 , pp. 99-104
    • Piani, D.1    Frei, K.2    Pfister, H.W.3    Fontana, A.4
  • 137
    • 0030006010 scopus 로고    scopus 로고
    • Immunohistochemical characterization of alterations in the distribution of amyloid precursor proteins and beta-amyloid peptide after experimental brain injury in the rat
    • J.E. Pierce, J.Q. Trojanowski, D.I. Graham, D.H. Smith, and T.K. McIntosh Immunohistochemical characterization of alterations in the distribution of amyloid precursor proteins and beta-amyloid peptide after experimental brain injury in the rat J. Neurosci. 16 1996 1083 1090
    • (1996) J. Neurosci. , vol.16 , pp. 1083-1090
    • Pierce, J.E.1    Trojanowski, J.Q.2    Graham, D.I.3    Smith, D.H.4    McIntosh, T.K.5
  • 138
    • 0033958462 scopus 로고    scopus 로고
    • Glutamate excitotoxicity in a model of multiple sclerosis
    • D. Pitt, P. Werner, and C.S. Raine Glutamate excitotoxicity in a model of multiple sclerosis Nat. Med. 6 2000 67 70
    • (2000) Nat. Med. , vol.6 , pp. 67-70
    • Pitt, D.1    Werner, P.2    Raine, C.S.3
  • 139
    • 0345327739 scopus 로고    scopus 로고
    • Glutamate uptake by oligodendrocytes: Implications for excitotoxicity in multiple sclerosis
    • D. Pitt, I.E. Nagelmeier, H.C. Wilson, and C.S. Raine Glutamate uptake by oligodendrocytes: implications for excitotoxicity in multiple sclerosis Neurology 61 2003 1113 1120
    • (2003) Neurology , vol.61 , pp. 1113-1120
    • Pitt, D.1    Nagelmeier, I.E.2    Wilson, H.C.3    Raine, C.S.4
  • 140
    • 0032535026 scopus 로고    scopus 로고
    • Chronic interleukin-6 alters NMDA receptor-mediated membrane responses and enhances neurotoxicity in developing CNS neurons
    • Z. Qiu, D.D. Sweeney, J.G. Netzeband, and D.L. Gruol Chronic interleukin-6 alters NMDA receptor-mediated membrane responses and enhances neurotoxicity in developing CNS neurons J. Neurosci. 18 1998 10445 10456
    • (1998) J. Neurosci. , vol.18 , pp. 10445-10456
    • Qiu, Z.1    Sweeney, D.D.2    Netzeband, J.G.3    Gruol, D.L.4
  • 141
    • 0043123387 scopus 로고    scopus 로고
    • Dysregulation of axonal sodium channel isoforms after adult-onset chronic demyelination
    • M.N. Rasband, T. Kagawa, E.W. Park, K. Ikenaka, and J.S. Trimmer Dysregulation of axonal sodium channel isoforms after adult-onset chronic demyelination J. Neurosci. Res. 73 2003 465 470
    • (2003) J. Neurosci. Res. , vol.73 , pp. 465-470
    • Rasband, M.N.1    Kagawa, T.2    Park, E.W.3    Ikenaka, K.4    Trimmer, J.S.5
  • 142
    • 0031474719 scopus 로고    scopus 로고
    • Antibodies to the axolemma-enriched fraction in the cerebrospinal fluid and serum of patients with multiple sclerosis and other neurological diseases
    • J.A. Rawes, V.P. Calabrese, O.A. Khan, and G.H. DeVries Antibodies to the axolemma-enriched fraction in the cerebrospinal fluid and serum of patients with multiple sclerosis and other neurological diseases Mult. Scler. 3 1997 363 369
    • (1997) Mult. Scler. , vol.3 , pp. 363-369
    • Rawes, J.A.1    Calabrese, V.P.2    Khan, O.A.3    Devries, G.H.4
  • 143
    • 0031439343 scopus 로고    scopus 로고
    • Nitric oxide donors reversibly block axonal conduction: Demyelinated axons are especially susceptible
    • E.J. Redford, R. Kapoor, and K.J. Smith Nitric oxide donors reversibly block axonal conduction: demyelinated axons are especially susceptible Brain 120 Pt. 12 1997 2149 2157
    • (1997) Brain , vol.120 , Issue.12 PART , pp. 2149-2157
    • Redford, E.J.1    Kapoor, R.2    Smith, K.J.3
  • 144
    • 0029816768 scopus 로고    scopus 로고
    • Neurons induced to express major histocompatibility complex class I antigen are killed via the perforin and not the Fas (APO-1/CD95) pathway
    • A. Rensing-Ehl, U. Malipiero, M. Irmler, J. Tschopp, D. Constam, and A. Fontana Neurons induced to express major histocompatibility complex class I antigen are killed via the perforin and not the Fas (APO-1/CD95) pathway Eur. J. Immunol. 26 1996 2271 2274
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2271-2274
    • Rensing-Ehl, A.1    Malipiero, U.2    Irmler, M.3    Tschopp, J.4    Constam, D.5    Fontana, A.6
  • 145
    • 0345432117 scopus 로고    scopus 로고
    • Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis
    • C. Rivera-Quinones, D. McGavern, J.D. Schmelzer, S.F. Hunter, P.A. Low, and M. Rodriguez Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis Nat. Med. 4 1998 187 193
    • (1998) Nat. Med. , vol.4 , pp. 187-193
    • Rivera-Quinones, C.1    McGavern, D.2    Schmelzer, J.D.3    Hunter, S.F.4    Low, P.A.5    Rodriguez, M.6
  • 146
    • 0031809195 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibitor, aminoguanidine, reduces inflammation and demyelination produced by Theilers virus infection
    • J.W. Rose, K.E. Hill, Y. Wada, C.I. Kurtz, I. Tsunoda, R.S. Fujinami, and A.H. Cross Nitric oxide synthase inhibitor, aminoguanidine, reduces inflammation and demyelination produced by Theilers virus infection J. Neuroimmunol. 81 1998 82 89
    • (1998) J. Neuroimmunol. , vol.81 , pp. 82-89
    • Rose, J.W.1    Hill, K.E.2    Wada, Y.3    Kurtz, C.I.4    Tsunoda, I.5    Fujinami, R.S.6    Cross, A.H.7
  • 147
    • 0031438499 scopus 로고    scopus 로고
    • The role of interleukin 1 in acute neurodegeneration and stroke: Pathophysiological and therapeutic implications
    • N. Rothwell, S. Allan, and S. Toulmond The role of interleukin 1 in acute neurodegeneration and stroke: pathophysiological and therapeutic implications J. Clin. Invest. 100 1997 2648 2652
    • (1997) J. Clin. Invest. , vol.100 , pp. 2648-2652
    • Rothwell, N.1    Allan, S.2    Toulmond, S.3
  • 148
    • 0028872327 scopus 로고
    • Reactive oxygen species are involved in the pathogenesis of experimental allergic encephalomyelitis in Lewis rats
    • S.R. Ruuls, J. Bauer, K. Sontrop, I. Huitinga, B.A. t Hart, and C.D. Dijkstra Reactive oxygen species are involved in the pathogenesis of experimental allergic encephalomyelitis in Lewis rats J. Neuroimmunol. 56 1995 207 217
    • (1995) J. Neuroimmunol. , vol.56 , pp. 207-217
    • Ruuls, S.R.1    Bauer, J.2    Sontrop, K.3    Huitinga, I.4    Hart, B.A.T.5    Dijkstra, C.D.6
  • 149
    • 0029873759 scopus 로고    scopus 로고
    • Aggravation of experimental allergic encephalomyelitis (EAE) by administration of nitric oxide (NO) synthase inhibitors
    • S.R. Ruuls, L.S. Van Der, K. Sontrop, I. Huitinga, and C.D. Dijkstra Aggravation of experimental allergic encephalomyelitis (EAE) by administration of nitric oxide (NO) synthase inhibitors Clin. Exp. Immunol. 103 1996 467 474
    • (1996) Clin. Exp. Immunol. , vol.103 , pp. 467-474
    • Ruuls, S.R.1    Van Der, L.S.2    Sontrop, K.3    Huitinga, I.4    Dijkstra, C.D.5
  • 150
    • 0034703186 scopus 로고    scopus 로고
    • In vivo and in vitro treatment with the synthetic cannabinoid CP55, 940 decreases the in vitro migration of macrophages in the rat: Involvement of both CB1 and CB2 receptors
    • P. Sacerdote, P. Massi, A.E. Panerai, and D. Parolaro In vivo and in vitro treatment with the synthetic cannabinoid CP55, 940 decreases the in vitro migration of macrophages in the rat: involvement of both CB1 and CB2 receptors J. Neuroimmunol. 109 2000 155 163
    • (2000) J. Neuroimmunol. , vol.109 , pp. 155-163
    • Sacerdote, P.1    Massi, P.2    Panerai, A.E.3    Parolaro, D.4
  • 151
    • 0031789948 scopus 로고    scopus 로고
    • Increased circulating antiganglioside antibodies in primary and secondary progressive multiple sclerosis
    • B.T. Sadatipour, J.M. Greer, and M.P. Pender Increased circulating antiganglioside antibodies in primary and secondary progressive multiple sclerosis Ann. Neurol. 44 1998 980 983
    • (1998) Ann. Neurol. , vol.44 , pp. 980-983
    • Sadatipour, B.T.1    Greer, J.M.2    Pender, M.P.3
  • 152
    • 0043025561 scopus 로고    scopus 로고
    • Excitatory amino acids and multiple sclerosis: Evidence from cerebrospinal fluid
    • P. Sarchielli, L. Greco, A. Floridi, A. Floridi, and V. Gallai Excitatory amino acids and multiple sclerosis: evidence from cerebrospinal fluid Arch. Neurol. 60 2003 1082 1088
    • (2003) Arch. Neurol. , vol.60 , pp. 1082-1088
    • Sarchielli, P.1    Greco, L.2    Floridi, A.3    Floridi, A.4    Gallai, V.5
  • 153
    • 0023904746 scopus 로고
    • Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro
    • K.W. Selmaj, and C.S. Raine Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro Ann. Neurol. 23 1988 339 346
    • (1988) Ann. Neurol. , vol.23 , pp. 339-346
    • Selmaj, K.W.1    Raine, C.S.2
  • 154
    • 0037092441 scopus 로고    scopus 로고
    • The cytokine network of Wallerian degeneration: Tumor necrosis factor-alpha, interleukin-1alpha, and interleukin-1beta
    • S. Shamash, F. Reichert, and S. Rotshenker The cytokine network of Wallerian degeneration: tumor necrosis factor-alpha, interleukin-1alpha, and interleukin-1beta J. Neurosci. 22 2002 3052 3060
    • (2002) J. Neurosci. , vol.22 , pp. 3052-3060
    • Shamash, S.1    Reichert, F.2    Rotshenker, S.3
  • 155
    • 0028047176 scopus 로고
    • Early detection of axonal injury after human head trauma using immunocytochemistry for beta-amyloid precursor protein
    • F.E. Sherriff, L.R. Bridges, and S. Sivaloganathan Early detection of axonal injury after human head trauma using immunocytochemistry for beta-amyloid precursor protein Acta Neuropathol. (Berl) 87 1994 55 62
    • (1994) Acta Neuropathol. (Berl) , vol.87 , pp. 55-62
    • Sherriff, F.E.1    Bridges, L.R.2    Sivaloganathan, S.3
  • 156
    • 0037449429 scopus 로고    scopus 로고
    • The role of cytokines and adhesion molecules in axon degeneration after peripheral nerve axotomy: A study in different knockout mice
    • H. Siebert, and W. Bruck The role of cytokines and adhesion molecules in axon degeneration after peripheral nerve axotomy: a study in different knockout mice Brain Res. 960 2003 152 156
    • (2003) Brain Res. , vol.960 , pp. 152-156
    • Siebert, H.1    Bruck, W.2
  • 157
    • 0026000851 scopus 로고
    • Immunocytochemical localization of N-acetyl-aspartate with monoclonal antibodies
    • M.L. Simmons, C.G. Frondoza, and J.T. Coyle Immunocytochemical localization of N-acetyl-aspartate with monoclonal antibodies Neuroscience 45 1991 37 45
    • (1991) Neuroscience , vol.45 , pp. 37-45
    • Simmons, M.L.1    Frondoza, C.G.2    Coyle, J.T.3
  • 158
    • 0033963231 scopus 로고    scopus 로고
    • Autoimmune encephalomyelitis ameliorated by AMPA antagonists
    • T. Smith, A. Groom, B. Zhu, and L. Turski Autoimmune encephalomyelitis ameliorated by AMPA antagonists Nat. Med. 6 2000 62 66
    • (2000) Nat. Med. , vol.6 , pp. 62-66
    • Smith, T.1    Groom, A.2    Zhu, B.3    Turski, L.4
  • 159
    • 0035067635 scopus 로고    scopus 로고
    • Electrically active axons degenerate when exposed to nitric oxide
    • K.J. Smith, R. Kapoor, S.M. Hall, and M. Davies Electrically active axons degenerate when exposed to nitric oxide Ann. Neurol. 49 2001 470 476
    • (2001) Ann. Neurol. , vol.49 , pp. 470-476
    • Smith, K.J.1    Kapoor, R.2    Hall, S.M.3    Davies, M.4
  • 161
    • 0035888090 scopus 로고    scopus 로고
    • Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis
    • R. Stanislaus, A.K. Singh, and I. Singh Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis J. Neurosci. Res. 66 2001 155 162
    • (2001) J. Neurosci. Res. , vol.66 , pp. 155-162
    • Stanislaus, R.1    Singh, A.K.2    Singh, I.3
  • 162
    • 0002918293 scopus 로고
    • Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ
    • L.A. Sternberger, and N.H. Sternberger Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ Proc. Natl. Acad. Sci. U. S. A. 80 1983 6126 6130
    • (1983) Proc. Natl. Acad. Sci. U. S. A. , vol.80 , pp. 6126-6130
    • Sternberger, L.A.1    Sternberger, N.H.2
  • 163
    • 0031972780 scopus 로고    scopus 로고
    • Pretreatment of astrocytes with interferon-alpha/beta prevents neuronal mitochondrial respiratory chain damage
    • V.C. Stewart, J.M. Land, J.B. Clark, and S.J. Heales Pretreatment of astrocytes with interferon-alpha/beta prevents neuronal mitochondrial respiratory chain damage J. Neurochem. 70 1998 432 434
    • (1998) J. Neurochem. , vol.70 , pp. 432-434
    • Stewart, V.C.1    Land, J.M.2    Clark, J.B.3    Heales, S.J.4
  • 164
    • 0030773332 scopus 로고    scopus 로고
    • Characterization of MRI response to treatment with interferon beta-1b: Contrast-enhancing MRI lesion frequency as a primary outcome measure
    • L.A. Stone, J.A. Frank, P.S. Albert, C.N. Bash, P.A. Calabresi, H. Maloni, and H.F. McFarland Characterization of MRI response to treatment with interferon beta-1b: contrast-enhancing MRI lesion frequency as a primary outcome measure Neurology 49 1997 862 869
    • (1997) Neurology , vol.49 , pp. 862-869
    • Stone, L.A.1    Frank, J.A.2    Albert, P.S.3    Bash, C.N.4    Calabresi, P.A.5    Maloni, H.6    McFarland, H.F.7
  • 165
    • 0031442231 scopus 로고    scopus 로고
    • Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases
    • J.F. Stover, K. Lowitzsch, and O.S. Kempski Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases Neurosci. Lett. 238 1997 25 28
    • (1997) Neurosci. Lett. , vol.238 , pp. 25-28
    • Stover, J.F.1    Lowitzsch, K.2    Kempski, O.S.3
  • 166
    • 0030042661 scopus 로고    scopus 로고
    • Correlation between electrophysiological effects of mexiletine and ischemic protection in central nervous system white matter
    • P.K. Stys, and H. Lesiuk Correlation between electrophysiological effects of mexiletine and ischemic protection in central nervous system white matter Neuroscience 71 1996 27 36
    • (1996) Neuroscience , vol.71 , pp. 27-36
    • Stys, P.K.1    Lesiuk, H.2
  • 167
    • 0026599820 scopus 로고
    • Tertiary and quaternary local anesthetics protect CNS white matter from anoxic injury at concentrations that do not block excitability
    • P.K. Stys, B.R. Ransom, and S.G. Waxman Tertiary and quaternary local anesthetics protect CNS white matter from anoxic injury at concentrations that do not block excitability J. Neurophysiol. 67 1992 236 240
    • (1992) J. Neurophysiol. , vol.67 , pp. 236-240
    • Stys, P.K.1    Ransom, B.R.2    Waxman, S.G.3
  • 168
    • 0038416100 scopus 로고    scopus 로고
    • Interleukin-1beta promotes oligodendrocyte death through glutamate excitotoxicity
    • J.L. Takahashi, F. Giuliani, C. Power, Y. Imai, and V.W. Yong Interleukin-1beta promotes oligodendrocyte death through glutamate excitotoxicity Ann. Neurol. 53 2003 588 595
    • (2003) Ann. Neurol. , vol.53 , pp. 588-595
    • Takahashi, J.L.1    Giuliani, F.2    Power, C.3    Imai, Y.4    Yong, V.W.5
  • 171
    • 0035184313 scopus 로고    scopus 로고
    • Coordinated induction of extracellular proteolysis systems during experimental autoimmune encephalomyelitis in mice
    • T. Teesalu, A.E. Hinkkanen, and A. Vaheri Coordinated induction of extracellular proteolysis systems during experimental autoimmune encephalomyelitis in mice Am. J. Pathol. 159 2001 2227 2237
    • (2001) Am. J. Pathol. , vol.159 , pp. 2227-2237
    • Teesalu, T.1    Hinkkanen, A.E.2    Vaheri, A.3
  • 173
    • 0026781413 scopus 로고
    • Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurons
    • S. Toulmond, X. Vige, D. Fage, and J. Benavides Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurons Neurosci. Lett. 144 1992 49 52
    • (1992) Neurosci. Lett. , vol.144 , pp. 49-52
    • Toulmond, S.1    Vige, X.2    Fage, D.3    Benavides, J.4
  • 175
    • 0034062423 scopus 로고    scopus 로고
    • Staging of multiple sclerosis (MS) lesions: Pathology of the time frame of MS
    • P. van der Valk, and C.J. De Groot Staging of multiple sclerosis (MS) lesions: pathology of the time frame of MS Neuropathol. Appl. Neurobiol. 26 2000 2 10
    • (2000) Neuropathol. Appl. Neurobiol. , vol.26 , pp. 2-10
    • Van Der Valk, P.1    De Groot, C.J.2
  • 176
    • 0030787471 scopus 로고    scopus 로고
    • Extensive peroxynitrite activity during progressive stages of central nervous system inflammation
    • R.C. van der Veen, D.R. Hinton, F. Incardonna, and F.M. Hofman Extensive peroxynitrite activity during progressive stages of central nervous system inflammation J. Neuroimmunol. 77 1997 1 7
    • (1997) J. Neuroimmunol. , vol.77 , pp. 1-7
    • Van Der Veen, R.C.1    Hinton, D.R.2    Incardonna, F.3    Hofman, F.M.4
  • 179
    • 0032806532 scopus 로고    scopus 로고
    • The activation of protein kinase C induces higher production of reactive oxygen species by mononuclear cells in patients with multiple sclerosis than in controls
    • O. Vladimirova, F.M. Lu, L. Shawver, and B. Kalman The activation of protein kinase C induces higher production of reactive oxygen species by mononuclear cells in patients with multiple sclerosis than in controls Inflammation Res. 48 1999 412 416
    • (1999) Inflammation Res. , vol.48 , pp. 412-416
    • Vladimirova, O.1    Lu, F.M.2    Shawver, L.3    Kalman, B.4
  • 180
    • 0028208495 scopus 로고
    • Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes
    • A. Volterra, D. Trotti, C. Tromba, S. Floridi, and G. Racagni Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes J. Neurosci. 14 1994 2924 2932
    • (1994) J. Neurosci. , vol.14 , pp. 2924-2932
    • Volterra, A.1    Trotti, D.2    Tromba, C.3    Floridi, S.4    Racagni, G.5
  • 181
    • 0034911054 scopus 로고    scopus 로고
    • Multiple sclerosis: Altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage
    • P. Werner, D. Pitt, and C.S. Raine Multiple sclerosis: altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage Ann. Neurol. 50 2001 169 180
    • (2001) Ann. Neurol. , vol.50 , pp. 169-180
    • Werner, P.1    Pitt, D.2    Raine, C.S.3
  • 182
    • 0033400628 scopus 로고    scopus 로고
    • Our shifting understanding of the role of nitric oxide in autoimmune encephalomyelitis: A review
    • D.O. Willenborg, M.A. Staykova, and W.B. Cowden Our shifting understanding of the role of nitric oxide in autoimmune encephalomyelitis: a review J. Neuroimmunol. 100 1999 21 35
    • (1999) J. Neuroimmunol. , vol.100 , pp. 21-35
    • Willenborg, D.O.1    Staykova, M.A.2    Cowden, W.B.3
  • 184
    • 0035339875 scopus 로고    scopus 로고
    • SIN-1, a nitric oxide donor, ameliorates experimental allergic encephalomyelitis in Lewis rats in the incipient phase: The importance of the time window
    • L.Y. Xu, J.S. Yang, H. Link, and B.G. Xiao SIN-1, a nitric oxide donor, ameliorates experimental allergic encephalomyelitis in Lewis rats in the incipient phase: the importance of the time window J. Immunol. 166 2001 5810 5816
    • (2001) J. Immunol. , vol.166 , pp. 5810-5816
    • Xu, L.Y.1    Yang, J.S.2    Link, H.3    Xiao, B.G.4
  • 185
    • 0031780040 scopus 로고    scopus 로고
    • Topographical and quantitative assessment of white matter injury following a focal ischaemic lesion in the rat brain
    • P.S. Yam, J. Patterson, D.I. Graham, T. Takasago, D. Dewar, and J. McCulloch Topographical and quantitative assessment of white matter injury following a focal ischaemic lesion in the rat brain Brain Res. Brain Res. Protoc. 2 1998 315 322
    • (1998) Brain Res. Brain Res. Protoc. , vol.2 , pp. 315-322
    • Yam, P.S.1    Patterson, J.2    Graham, D.I.3    Takasago, T.4    Dewar, D.5    McCulloch, J.6
  • 186
    • 0035405886 scopus 로고    scopus 로고
    • Metalloproteinases in biology and pathology of the nervous system
    • V.W. Yong, C. Power, P. Forsyth, and D.R. Edwards Metalloproteinases in biology and pathology of the nervous system Nat. Rev., Neurosci. 2 2001 502 511
    • (2001) Nat. Rev., Neurosci. , vol.2 , pp. 502-511
    • Yong, V.W.1    Power, C.2    Forsyth, P.3    Edwards, D.R.4
  • 187
    • 0028911077 scopus 로고
    • Differential modulation of human glutamate transporter subtypes by arachidonic acid
    • N. Zerangue, J.L. Arriza, S.G. Amara, and M.P. Kavanaugh Differential modulation of human glutamate transporter subtypes by arachidonic acid J. Biol. Chem. 270 1995 6433 6435
    • (1995) J. Biol. Chem. , vol.270 , pp. 6433-6435
    • Zerangue, N.1    Arriza, J.L.2    Amara, S.G.3    Kavanaugh, M.P.4
  • 188
    • 0034021267 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors in the pathogenesis of multiple sclerosis
    • G.X. Zhang, C.M. Baker, D.L. Kolson, and A.M. Rostami Chemokines and chemokine receptors in the pathogenesis of multiple sclerosis Mult. Scler. 6 2000 3 13
    • (2000) Mult. Scler. , vol.6 , pp. 3-13
    • Zhang, G.X.1    Baker, C.M.2    Kolson, D.L.3    Rostami, A.M.4
  • 189
    • 0037407910 scopus 로고    scopus 로고
    • Dendritic and synaptic pathology in experimental autoimmune encephalomyelitis
    • B. Zhu, L. Luo, G.R. Moore, D.W. Paty, and M.S. Cynader Dendritic and synaptic pathology in experimental autoimmune encephalomyelitis Am. J. Pathol. 162 2003 1639 1650
    • (2003) Am. J. Pathol. , vol.162 , pp. 1639-1650
    • Zhu, B.1    Luo, L.2    Moore, G.R.3    Paty, D.W.4    Cynader, M.S.5


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