Macrophages in multiple sclerosis

Immunobiology

Volumn 195, Issue 4-5, 1996, Pages 588-600

  Brück, Wolfgang ^a,e   Sommermeier, Nicole ^a   Bergmann, Markus ^b   Zettl, Uwe ^c   Goebel, Hans H ^c   Kretzschmar, Hans A ^a   Lassmann, Hans ^d  

^a Institute of Neuropathology   (Germany)

^b Bremen   (Germany)

^c Department of Neuropathology ^*  (Germany)

^d ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^e Institut fur Neuropathologie   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CELL MARKER; MYELIN;

CELL DIFFERENTIATION; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; DEMYELINATION; EFFECTOR CELL; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; INFLAMMATION; MACROPHAGE; MULTIPLE SCLEROSIS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REMYELINIZATION;

EID: 0029828534     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0171-2985(96)80024-6     Document Type: Conference Paper

References (40)

1. LASSMANN, H. 1983. Comparative neuropathology of chronic experimental allergic encephalomyelitis and multiple sclerosis. Springer-Verlag, Berlin Heidelberg.
2. PRINEAS, J. W. 1985. The neuropathology of multiple sclerosis. In: Koetsier, J. C. (ed.) Handbook of clinical neurology, Vol. 3 (47): Demyelinating diseases. Elsevier Science Publishers, Amsterdam, p. 213.
3. HAUSER, S. L., A. K. BHAN, F. GILLES, M. KEMP, C. KERR, and H. L. WEINER. 1986. Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions. Ann. Neurol. 19: 578.
4. ADAMS, C. W. M., R. N. POSTON, and S. J. BUK. 1989. Pathology, histochemistry and immunocytochemistry of lesions in acute multiple sclerosis. J. Neurol. Sci. 92: 291.
5. ESIRI, M. M., and M. C. READING. 1987. Macrophage populations associated with multiple sclerosis plaques. Neuropathol. Appl. Neurobiol. 13: 451.
6. ESIRI, M. M., and C. S. MORRIS. 1991. Immunocytochemical study of macrophages and microglial cells and extracellular matrix components in human CNS disease 2. Non-neoplastic diseases. J. Neurol. Sci. 101: 59.
7. BOYLE, E. A. and P. L. MCGEER. 1990. Cellular immune response in multiple sclerosis plaques. Am. J. Pathol. 137: 575.
8. CUZNER, M. L., G. M. HAYES, J. NEWCOMBE, and M. N. WOODROOFE. 1988. The nature of inflammatory components during demyelination in multiple sclerosis. J. Neuroimmunol. 20: 203.
9. BRÜCK, W., P. PORADA, S. POSER, P. RIECKMANN, F. HANEFELD, H. A. KRETZSCHMAR, and H. LASSMANN. 1995. Monocyte/macrophage differentiation in early multiple sclerosis lesions. Ann. Neurol. 38: 788.
10. POSER, S., W. LÜER, H. BRUHN, J. FRAHM, Y. BRÜCK, and K. FELGENHAUER. 1992. Acute demyelinating disease. Classification and non-invasive diagnosis. Acta Neurol. Scand. 86: 579.
11. LASSMANN, H., G. SUCHANEK, and K. OZAWA. 1994. Histopathology and the blood-cerebrospinal fluid barrier in Multiple Sclerosis. Ann. Neurol. 36: S42.
12. MARBURG, O. 1906. Die sogenannte akute multiple sklerose (Encephalomyelitis periaxialis scleroticans). Jahrb. Psychiat. Neurol. 27: 213.
13. BRÜCK, W., M. SCHMIED, G. SUCHANEK, Y. BRÜCK, H. BRETTSCHOPF, S. POSER, S. PIDDLESDEN, and H. LASSMANN. 1994. Oligodendrocytes in the early course of multiple sclerosis. Ann. Neurol. 35: 65.
14. PIDDLESDEN, S. J., H. LASSMANN, F. ZIMPRICH, B. P. MORGAN, and C. LININGTON. 1993. The demyelinating potential of antibodies to myelin oligodendrocyte glycoprotein is related to their ability to fix complement. Am. J. Pathol. 143: 555.
15. RADZUN, H. J., M. L. HANSMANN, H. J. HEIDEBRECHT, S. BÖDEWADT-RADZUN, H. H. WACKER, H. KREIPE, H. LUMBECK, C. HERNANDEZ, C. KUHN, and M. R. PARWARESCH. 1991. Detection of a monocyte/macrophage differentiation antigen in routinely processed paraffin-embedded tissues by monoclonal antibody Ki-M1P. Lab. Invest. 65: 306.
16. PARWARESCH, M. R., H. J. RADZUN, M. L. HANSMANN, and K. P. PETERS. 1983. Monoclonal antibody Ki-M4 specifically recognizes human dendritic reticulum cells (follicular cendritic cells) and their possible precursors in blood. Blood 62: 585.
17. ZWADLO, G., R. SCHLEGEL, and C. SORG. 1986. A monoclonal antibody to a subset of human monocytes found only in the peripheral blood and inflammatory tissues. J. Immunol. 137: 512.
18. BHARDWAJ, R. S., C. ZOTZ, G. ZWADLO-KLARWASSER, J. ROTH, M. GOEBELER, K. MAHNKE, M. FALK, G. MEINARDUS-HAGER, and C. SORG. 1992. The calcium-binding proteins MRP8 and MRP14 form a membrane-associated heterodimer in a subset of monocytes/macrophages present in acute but absent in chronic inflammatory lesions. Eur. J. Immunol. 22: 1891.
19. ZWADLO, G., E. B. BRÖCKER, D. B. VON BASSEWITZ, U. FEIGE, and C. SORG. 1985. A monoclonal antibody to a differentiation antigen present on mature human macrophages and absent from monocytes. J. Immunol. 134: 1487.
20. ADAMS, C. W. M., and R. N. POSTON. 1990. Macrophage histology in paraffin-embedded multiple sclerosis plaques is demonstrated by the monoclonal panmacrophage marker HAM-56: correlation with chronicity of the lesion. Acta Neuropathol. (Berl.) 80: 208.
21. OZAWA, K., G. SUCHANEK, H. BREITSCHOPF, W. BRÜCK, H. BUDKA, K. JELLINGER, and H. LASSMANN. 1994. Patterns of oligodendroglia pathology in multiple sclerosis. Brain 117: 1311.
22. PAULUS, W., W. ROGGENDORF, and T. KIRCHNER. 1992. Ki-M1P as a marker for microglia and brain macrophages in routinely processed human tissues. Acta Neuropathol. (Berl.) 84: 538.
23. DIJKSTRA, C. D., C. J. A. DE GROOT, and I. HUTTINGA. 1992. The role of macrophages in demyelination. J. Neuroimmunol. 40: 183.
24. HUITINGA, I., N. VAN ROOIJEN, C. J. A. DE GROOT, B. M. J. UITDEHAAG, and C. D. DIJKSTRA. 1990. Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages. J. Exp. Med. 172: 1025.
25. WOODROOFE, M. N., A. S. BELLAMY, M. FELDMANN, A. N. DAVISON, and M. L. CUZNER. 1986. Immunocytochemical characterisation of the immune reaction in the central nervous system in multiple sclerosis. Possible role for microglia in lesion growth. J. Neurol. Sci. 74: 135.
26. BÖ, L., S. MÖRK, P. A. KONG, H. NYLAND, C. A. PARDO, and B. D. TRAPP. 1994. Detection of MHC class II-antigens on macrophages and microglia, but not on astrocytes and endothelia in active multiple sclerosis lesions. J. Neuroimmunol. 51: 135.
27. NEWCOMBE, J., H. LI, and M. L. CUZNER. 1994. Low density lipoprotein uptake by macrophages in multiple sclerosis plaques: implications for pathogenesis. Neuropathol. Appl. Neurobiol. 20: 152.
28. WOODROOFE, M. N., and M. L. CUZNER. 1993. Cytokine mRNA expression in inflammatory multiple sclerosis lesions: detection by non-radioactive in situ hybridization. Cytokine 5: 583.
29. BANIK, N. L. 1992. Pathogenesis of myelin breakdown in demyelinating diseases: role of proteolytic enzymes. Neurobiology 16: 257.
30. BÖ, L., T. M. DAWSON, S. WESSELINGH, S. MÖRK, S. CHOI, P. N. KONG, D. HANLEY, and B. D. TRAPP. 1994. Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains. Ann. Neurol. 36: 778.
31. RUULS, S. R., J. BAUER, K. SONTROP, I. HUITINGA, B. A. T'HART, and C. D. DIJKSTRA. 1995. Reactive oxygen species are involved in the pathogenesis of experimental allergic encephalomyelitis in Lewis rats. J. Neuroimmunol. 56: 207.
32. LASSMANN, H., M. SCHMIED, K. VASS, and W. F. HICKEY. 1993. Bone marrow-derived elements and resident microglia in brain inflammation. Glia 7: 19.
33. ULVESTAD, E., K. WILLIAMS, S. MORK, J. ANTEL, and H. NYLAND. 1994. Phenotypic differences between human monocytes/macrophages and microglial cells studied in situ and in vitro. J. Neuropathol. Exp. Neurol. 53: 492.
34. HESSIAN, P. A., J. EDGEWORTH, and N. HOGG. 1993. MRP-8 and MRP-14, two abundant Ca2+-binding proteins of neutrophils and monocytes. J. Leukocyte Biol. 53: 197.
35. MURAO, S. 1994. Review: two calcium-binding proteins, MRP8 and MRP14: a protein complex associated with neutrophil and monocyte activation. Acta Histochem. Cytochem. 27: 107.
36. ODINK, K., N. CERLETTI, J. BRÜGGEN, R. G. CLERC, L. TARCSAY, G. ZWADLO, G. GERHARDS, R. SCHLEGEL, and C. SORG. 1987. Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis. Nature 330: 80.
37. AKIYAMA, H., K. IKEDA, M. KATOH, E. G. MCGEER, and P. L. MCGEER. 1994. Expression of MRP14, 27E10, interferon-a and leukocyte common antigen by reactive microglia in postmortem human brain tissue. J. Neuroimmunol. 50: 195.
38. GUSEO, A., and K. JELLINGER. 1975. The significance of perivascular infiltrations in multiple sclerosis. Neurology 211: 51.
39. REVESZ, T., D. KIDD, A. J. THOMPSON, R. O. BARNARD, and W. I. MCDONALD. 1994. A comparison of the pathology of primary and secondary progressive multiple sclerosis. Brain 117: 759.
40. HUITINGA, I., S. R. RUULS, S. JUNG, N. VAN ROOIJEN, H.-P. HARTUNG, and C. D. DIJKSTRA. 1995. Macrophages in T cell-mediated, demyelinating, and chronic relapsing experimental autoimmune encephalomyelitis in Lewis rats. Clin. Exp. Immunol. 100: 344.