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Volumn 75, Issue 3, 1997, Pages 174-186

The role of nitric oxide in multiple sclerosis

Author keywords

Astrocytes; Demyelination; Microglia; Multiple sclerosis; Nitric oxide

Indexed keywords

AMINOGUANIDINE; CYTOKINE; N(G) METHYLARGININE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE;

EID: 0030948467     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001090050102     Document Type: Review
Times cited : (136)

References (149)
  • 1
    • 0000590508 scopus 로고
    • Glial cells as nitric oxide sources and targets
    • Vincent S (ed) Academic. San Diego
    • Murphy S, Grzybicki DM, Simmons ML (1995) Glial cells as nitric oxide sources and targets. In: Vincent S (ed) Nitric oxide in the nervous system. Academic. San Diego, pp 164-190
    • (1995) Nitric Oxide in the Nervous System , pp. 164-190
    • Murphy, S.1    Grzybicki, D.M.2    Simmons, M.L.3
  • 2
    • 0028966205 scopus 로고
    • Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: Implications for HIV-associated neurological disease
    • Bukrinsky MI, Nottet HSLM, Schmidtmayerova H, Dubrovsky L, Flanagan CR, Mullins ME, Lipton SA, Gendelman HE (1995) Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease. J Exp Med 181:735-745
    • (1995) J Exp Med , vol.181 , pp. 735-745
    • Bukrinsky, M.I.1    Nottet, H.S.L.M.2    Schmidtmayerova, H.3    Dubrovsky, L.4    Flanagan, C.R.5    Mullins, M.E.6    Lipton, S.A.7    Gendelman, H.E.8
  • 3
    • 0027948094 scopus 로고
    • Triggering of human monocyte activation through CD69, a member of the natural killer cell gene complex family of signal transducing receptors
    • De Maria R, Cifone MG, Trotta R, Rippo MR, Festuccia C, Santoni A, Testi R (1994) Triggering of human monocyte activation through CD69, a member of the natural killer cell gene complex family of signal transducing receptors. J Exp Med 180:1999-2004
    • (1994) J Exp Med , vol.180 , pp. 1999-2004
    • De Maria, R.1    Cifone, M.G.2    Trotta, R.3    Rippo, M.R.4    Festuccia, C.5    Santoni, A.6    Testi, R.7
  • 5
    • 0026766892 scopus 로고
    • Autoimmune disease and the nervous system: Biochemical, molecular, and clinical update
    • Merrill JE, Graves MC, Mulder DG (1992) Autoimmune disease and the nervous system: biochemical, molecular, and clinical update. West J Med 156:639-646
    • (1992) West J Med , vol.156 , pp. 639-646
    • Merrill, J.E.1    Graves, M.C.2    Mulder, D.G.3
  • 6
    • 0024366885 scopus 로고
    • Tumor necrosis factor identified in multiple sclerosis brain
    • Hofman FM, Hinton DR, Johnson K, Merrill JE (1989) Tumor necrosis factor identified in multiple sclerosis brain. J Exp Med 170:607-612
    • (1989) J Exp Med , vol.170 , pp. 607-612
    • Hofman, F.M.1    Hinton, D.R.2    Johnson, K.3    Merrill, J.E.4
  • 9
    • 0025107677 scopus 로고
    • Cytokine accumulations in CSF of multiple sclerosis patients: Frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6
    • Hauser SL, Doolittle DH, Lincoln R, Brown RH, Dinarello CA (1990) Cytokine accumulations in CSF of multiple sclerosis patients: frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6. Neurol 40:1735-1739
    • (1990) Neurol , vol.40 , pp. 1735-1739
    • Hauser, S.L.1    Doolittle, D.H.2    Lincoln, R.3    Brown, R.H.4    Dinarello, C.A.5
  • 10
    • 0028095562 scopus 로고
    • Increased transforming growth factor-β, interleukin-4, and interferon-γ in multiple sclerosis
    • Link J, Soderstrom M, Olsson T, Hojeberg B, Ljungdahl A, Link H (1994) Increased transforming growth factor-β, interleukin-4, and interferon-γ in multiple sclerosis. Ann Neurol 36:379-386
    • (1994) Ann Neurol , vol.36 , pp. 379-386
    • Link, J.1    Soderstrom, M.2    Olsson, T.3    Hojeberg, B.4    Ljungdahl, A.5    Link, H.6
  • 11
    • 0026948591 scopus 로고
    • Tumor necrosis factor a production as a possible predictor of relapse in patients with multiple sclerosis
    • Chofflon M, Juillard C, Juillard P, Gauthier G, Grau GE (1992) Tumor necrosis factor a production as a possible predictor of relapse in patients with multiple sclerosis. Eur Cytokine Netw 316:523-531
    • (1992) Eur Cytokine Netw , vol.316 , pp. 523-531
    • Chofflon, M.1    Juillard, C.2    Juillard, P.3    Gauthier, G.4    Grau, G.E.5
  • 12
    • 0027202071 scopus 로고
    • Decreased IL-3 production by peripheral blood mononuclear cells in patients with multiple sclerosis
    • Huberman M, Shalit F, Roth-Deri I, Gutman B, Kott E, Sredni B (1993) Decreased IL-3 production by peripheral blood mononuclear cells in patients with multiple sclerosis. J Neurol Sci 118:79-82
    • (1993) J Neurol Sci , vol.118 , pp. 79-82
    • Huberman, M.1    Shalit, F.2    Roth-Deri, I.3    Gutman, B.4    Kott, E.5    Sredni, B.6
  • 13
    • 0023794099 scopus 로고
    • Increased production of interferon gamma and tumor necrosis factor precedes clinical manifestation in multiple sclerosis: Do cytokines trigger off exacerbations?
    • Beck J, Rondot P, Catinot L, Falcoff E, Kirchner H, Wietzerbin J (1988) Increased production of interferon gamma and tumor necrosis factor precedes clinical manifestation in multiple sclerosis: do cytokines trigger off exacerbations? Acta Neurol Scand 78:318-326
    • (1988) Acta Neurol Scand , vol.78 , pp. 318-326
    • Beck, J.1    Rondot, P.2    Catinot, L.3    Falcoff, E.4    Kirchner, H.5    Wietzerbin, J.6
  • 14
    • 0027418515 scopus 로고
    • Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomised, double-blind, placebo-controlled trial
    • The IFN-beta Multiple Sclerosis Study Group (1993) Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomised, double-blind, placebo-controlled trial. Neurol 43:655-661
    • (1993) Neurol , vol.43 , pp. 655-661
  • 15
    • 0025820499 scopus 로고
    • Interferon-β specifically inhibits interferon-γ-induced class II major histocompatibility complex gene transcription in a human astrocytoma cell line
    • Ransohoff RM, Devajyothi C, Estes ML, Babcock G, Rudick RA (1991) Interferon-β specifically inhibits interferon-γ-induced class II major histocompatibility complex gene transcription in a human astrocytoma cell line. J Neuroimmunol 33:103-112
    • (1991) J Neuroimmunol , vol.33 , pp. 103-112
    • Ransohoff, R.M.1    Devajyothi, C.2    Estes, M.L.3    Babcock, G.4    Rudick, R.A.5
  • 16
    • 0026601932 scopus 로고
    • Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice
    • Merrill JE, Kono DH, Clayton J, Ando DG, Hinton DR, Hofman FM (1992) Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice. Proc Natl Acad Sci USA 89:574-578
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 574-578
    • Merrill, J.E.1    Kono, D.H.2    Clayton, J.3    Ando, D.G.4    Hinton, D.R.5    Hofman, F.M.6
  • 17
    • 0026707402 scopus 로고
    • Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery
    • Kennedy MK, Torrance DS, Picha KS, Mohler KM (1992) Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J Immunol 149:2496-2505
    • (1992) J Immunol , vol.149 , pp. 2496-2505
    • Kennedy, M.K.1    Torrance, D.S.2    Picha, K.S.3    Mohler, K.M.4
  • 18
  • 19
    • 0025015655 scopus 로고
    • Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages
    • Huitinga I, van Rooijen N, de Groot CJA, Uitdehaag BMJ, Dijkstra CD (1990) Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages. J Exp Med 172:1025-1034
    • (1990) J Exp Med , vol.172 , pp. 1025-1034
    • Huitinga, I.1    Van Rooijen, N.2    De Groot, C.J.A.3    Uitdehaag, B.M.J.4    Dijkstra, C.D.5
  • 20
    • 0028960035 scopus 로고
    • Cytokines and murine autoimmune encephalomyelitis: Inhibition or enhancement of disease with antibodies to select cytokines, or by delivery of exogenous cytokines using a recombinant vaccinia virus system
    • Willenborg DO, Fordham SA, Cowden WB, Ramshaw IA (1995) Cytokines and murine autoimmune encephalomyelitis: inhibition or enhancement of disease with antibodies to select cytokines, or by delivery of exogenous cytokines using a recombinant vaccinia virus system. Scand J Immunol 41:31-41
    • (1995) Scand J Immunol , vol.41 , pp. 31-41
    • Willenborg, D.O.1    Fordham, S.A.2    Cowden, W.B.3    Ramshaw, I.A.4
  • 21
    • 0028089802 scopus 로고
    • Macrophage-inactivating IL-13 suppresses experimental autoimmune encephalomyelitis in rats
    • Cash E, Minty A, Ferrara P, Caput D, Fradelizi D, Rott O (1994) Macrophage-inactivating IL-13 suppresses experimental autoimmune encephalomyelitis in rats. J Immunol 153:4258-4267
    • (1994) J Immunol , vol.153 , pp. 4258-4267
    • Cash, E.1    Minty, A.2    Ferrara, P.3    Caput, D.4    Fradelizi, D.5    Rott, O.6
  • 22
    • 0028245010 scopus 로고
    • Interleukin-10 prevents experimental allergic encephalomyelitis in rats
    • Rott O, Fleischer B, Cash E (1994) Interleukin-10 prevents experimental allergic encephalomyelitis in rats. Eur J Immunol 24:1434-1440
    • (1994) Eur J Immunol , vol.24 , pp. 1434-1440
    • Rott, O.1    Fleischer, B.2    Cash, E.3
  • 23
    • 0026713026 scopus 로고
    • Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulution transforming growth factor β, interleukin 4, and prostaglandin e expression in the brain
    • Khoury SJ, Hancock WW, Weiner HL (1992) Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulution transforming growth factor β, interleukin 4, and prostaglandin E expression in the brain. J Exp Med 176:1355-1364
    • (1992) J Exp Med , vol.176 , pp. 1355-1364
    • Khoury, S.J.1    Hancock, W.W.2    Weiner, H.L.3
  • 24
    • 0029155652 scopus 로고
    • Human immunodeficiency virus 1 envelope proteins induce interleukin 1, tumor necrosis factor α, and nitric oxide in glial cultures from fetal, neonatal, and adult human brain
    • Koka P, He K, Zack JA, Kitchen S, Peacock W, Fried I, Tran T, Yashar SS, Merrill JE (1995) Human immunodeficiency virus 1 envelope proteins induce interleukin 1, tumor necrosis factor α, and nitric oxide in glial cultures from fetal, neonatal, and adult human brain. J Exp Med 182:941-952
    • (1995) J Exp Med , vol.182 , pp. 941-952
    • Koka, P.1    He, K.2    Zack, J.A.3    Kitchen, S.4    Peacock, W.5    Fried, I.6    Tran, T.7    Yashar, S.S.8    Merrill, J.E.9
  • 25
    • 0027937121 scopus 로고
    • Nitric oxide synthase: MRNA expression of different isoforms in human monocytes/macrophages
    • Reiling N, Ulmer AJ, Duchrow M, Ernst M, Flad H-D, Hauschildt S (1994) Nitric oxide synthase: mRNA expression of different isoforms in human monocytes/macrophages. Eur J Immunol 24:1941-1944
    • (1994) Eur J Immunol , vol.24 , pp. 1941-1944
    • Reiling, N.1    Ulmer, A.J.2    Duchrow, M.3    Ernst, M.4    Flad, H.-D.5    Hauschildt, S.6
  • 26
    • 0027161216 scopus 로고
    • Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide
    • Merrill JE, Ignarro LJ, Sherman MP, Melinek J, Lane TE (1993) Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J Immunol 151:2132-2141
    • (1993) J Immunol , vol.151 , pp. 2132-2141
    • Merrill, J.E.1    Ignarro, L.J.2    Sherman, M.P.3    Melinek, J.4    Lane, T.E.5
  • 27
    • 0029065301 scopus 로고
    • Direct activation of murine peritoneal macrophages for nitric oxide production and tumor cell killing by interferon-γ
    • Dileepan KN, Page JC, Li Y, Stechschulte DJ (1995) Direct activation of murine peritoneal macrophages for nitric oxide production and tumor cell killing by interferon-γ. J Interfer Cyto Res 15:387-394
    • (1995) J Interfer Cyto Res , vol.15 , pp. 387-394
    • Dileepan, K.N.1    Page, J.C.2    Li, Y.3    Stechschulte, D.J.4
  • 28
    • 0027422993 scopus 로고
    • Induction of nitric oxide synthase activity in human astrocytes by interleukin-1β and interferon γ
    • Lee SC, Dickson DW, Liu W, Brosnan CF (1993) Induction of nitric oxide synthase activity in human astrocytes by interleukin-1β and interferon γ. J Neuroimmunol 46:19-24
    • (1993) J Neuroimmunol , vol.46 , pp. 19-24
    • Lee, S.C.1    Dickson, D.W.2    Liu, W.3    Brosnan, C.F.4
  • 29
    • 0029045806 scopus 로고
    • IL-12 induced protection against blood-stage Plasmodium chabaudi AS requires IFN-γ and TNF-α and occurs via a nitric oxide-dependent mechanism
    • Stevenson MM, Tam MF, Wolf SF, Sher A (1995) IL-12 induced protection against blood-stage Plasmodium chabaudi AS requires IFN-γ and TNF-α and occurs via a nitric oxide-dependent mechanism. J Immunol 155:2545-2556
    • (1995) J Immunol , vol.155 , pp. 2545-2556
    • Stevenson, M.M.1    Tam, M.F.2    Wolf, S.F.3    Sher, A.4
  • 30
    • 0026715051 scopus 로고
    • In vivo induction of nitrite and nitrate by tumor necrosis factor, lymphotoxin, and interleukin-1: Possible roles in malaria
    • Rockett KA, Awburn BMM, Aggarwal BB, Cowden WB, Clark IA (1992) In vivo induction of nitrite and nitrate by tumor necrosis factor, lymphotoxin, and interleukin-1: possible roles in malaria. Infect Immun 60:3725-3730
    • (1992) Infect Immun , vol.60 , pp. 3725-3730
    • Rockett, K.A.1    Awburn, B.M.M.2    Aggarwal, B.B.3    Cowden, W.B.4    Clark, I.A.5
  • 31
    • 0028598750 scopus 로고
    • Reactive gliosis as a consequence of interleukin-6 expression in the brain: Studies in transgenic mice
    • Chiang C-S, Stalder A, Samimi A, Campbell IL (1994) Reactive gliosis as a consequence of interleukin-6 expression in the brain: studies in transgenic mice. Dev Neurosci 16:212-221
    • (1994) Dev Neurosci , vol.16 , pp. 212-221
    • Chiang, C.-S.1    Stalder, A.2    Samimi, A.3    Campbell, I.L.4
  • 34
    • 0027485036 scopus 로고
    • Interferon-gamma, but not interferon-alpha beta, synergizes with tumor necrosis factor-alpha and lipid A in the induction of nitric oxide production by murine L929 cells
    • Fast DJ, Lynch RC, Leu RW (1993) Interferon-gamma, but not interferon-alpha beta, synergizes with tumor necrosis factor-alpha and lipid A in the induction of nitric oxide production by murine L929 cells. J Interferon Res 13:271-277
    • (1993) J Interferon Res , vol.13 , pp. 271-277
    • Fast, D.J.1    Lynch, R.C.2    Leu, R.W.3
  • 35
    • 0028180701 scopus 로고
    • Role of endogenous interferon-beta in lipopolysaccharide-triggered activation of the inducible nitric oxide synthase gene in the mouse macrophage cell line, J774
    • Fujihara M, Ito N, Pace JL, Watanabe Y, Russell SW, Suzuki T (1994) Role of endogenous interferon-beta in lipopolysaccharide-triggered activation of the inducible nitric oxide synthase gene in the mouse macrophage cell line, J774. J Biol Chem 129:12773-12778
    • (1994) J Biol Chem , vol.129 , pp. 12773-12778
    • Fujihara, M.1    Ito, N.2    Pace, J.L.3    Watanabe, Y.4    Russell, S.W.5    Suzuki, T.6
  • 36
    • 0028137726 scopus 로고
    • Necessity and sufficiency of beta interferon for nitric oxide production in mouse peritoneal macrophages
    • Zhang X, Alley EW, Russell SW, Morrison DC (1994) Necessity and sufficiency of beta interferon for nitric oxide production in mouse peritoneal macrophages. Infect Immun 62: 33-40
    • (1994) Infect Immun , vol.62 , pp. 33-40
    • Zhang, X.1    Alley, E.W.2    Russell, S.W.3    Morrison, D.C.4
  • 37
    • 0028243802 scopus 로고
    • Interleukin-13 alters the activation state of murine macrophages in vitro: Comparison with interleukin-4 and interferon-γ
    • Doyle AG, Herbein G, Montener LJ, Minty AJ, Caput D, Ferrara P, Gordon S (1994) Interleukin-13 alters the activation state of murine macrophages in vitro: comparison with interleukin-4 and interferon-γ. Eur J Immunol 24:1441-1445
    • (1994) Eur J Immunol , vol.24 , pp. 1441-1445
    • Doyle, A.G.1    Herbein, G.2    Montener, L.J.3    Minty, A.J.4    Caput, D.5    Ferrara, P.6    Gordon, S.7
  • 38
    • 0025311615 scopus 로고
    • Macrophage deactivating factor and transforming growth factors-β1, -β2,-β3 inhibit induction of macrophage nitrogen oxide synthesis by IFNγ
    • Ding A, Nathan C. F. Graycar J Derynck R Stuehr D. J Srimal S (1990) Macrophage deactivating factor and transforming growth factors-β1, -β2,-β3 inhibit induction of macrophage nitrogen oxide synthesis by IFNγ. J Immunol 145: 940-944
    • (1990) J Immunol , vol.145 , pp. 940-944
    • Ding, A.1    Nathan, C.F.2    Graycar, J.3    Derynck, R.4    Stuehr, D.J.5    Srimal, S.6
  • 39
    • 23444455658 scopus 로고
    • Inactivation of nitric oxide synthase after prolonged incubation of mouse macrophages with IFN-γ and bacterial lipopolysacchardide
    • Vodovotz Y, Kwon NS, Pospischil M, Manning J, Paik J, Nathan C (1994) Inactivation of nitric oxide synthase after prolonged incubation of mouse macrophages with IFN-γ and bacterial lipopolysacchardide. J Immunol 152:4110-4118
    • (1994) J Immunol , vol.152 , pp. 4110-4118
    • Vodovotz, Y.1    Kwon, N.S.2    Pospischil, M.3    Manning, J.4    Paik, J.5    Nathan, C.6
  • 40
    • 0027203305 scopus 로고
    • Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor β
    • Vodovotz Y, Bogdan C, Paik J, Xie Q-W, Nathan C (1993) Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor β. J Exp Med 178: 605-613
    • (1993) J Exp Med , vol.178 , pp. 605-613
    • Vodovotz, Y.1    Bogdan, C.2    Paik, J.3    Xie, Q.-W.4    Nathan, C.5
  • 42
    • 0028133381 scopus 로고
    • Transforming growth factor beta 1 and gamma interferon provide opposing signals to lipopolysaccharide-activated mouse macrophages
    • Hausmann EH, Hao SY, Pace JL, Parmely MJ (1994) Transforming growth factor beta 1 and gamma interferon provide opposing signals to lipopolysaccharide-activated mouse macrophages. Infect Immun 62:3625-3632
    • (1994) Infect Immun , vol.62 , pp. 3625-3632
    • Hausmann, E.H.1    Hao, S.Y.2    Pace, J.L.3    Parmely, M.J.4
  • 43
    • 0028083246 scopus 로고
    • Tumor-induced regulation of suppressor macrophage nitric oxide and TNFD-alpha production. Role of tumor-derived IL-10, TGF-beta, and prostaglandin E2
    • Alleva DG, Burger CJ, Elgert KD (1994) Tumor-induced regulation of suppressor macrophage nitric oxide and TNFD-alpha production. Role of tumor-derived IL-10, TGF-beta, and prostaglandin E2. J Immunol 153:1674-1686
    • (1994) J Immunol , vol.153 , pp. 1674-1686
    • Alleva, D.G.1    Burger, C.J.2    Elgert, K.D.3
  • 44
    • 0028566361 scopus 로고
    • Regulation of inducible nitric oxide synthase gene by interleukin-1 beta in rat vascular endothelial cells
    • Kanno K, Hirata Y, Imai T, Iwashina M, Marumo F (1994) Regulation of inducible nitric oxide synthase gene by interleukin-1 beta in rat vascular endothelial cells. Am J Physiol 267:H2318-2324
    • (1994) Am J Physiol , vol.267
    • Kanno, K.1    Hirata, Y.2    Imai, T.3    Iwashina, M.4    Marumo, F.5
  • 45
    • 0028236275 scopus 로고
    • Regulation of inducible nitric oxide synthase mRNA levels by LPS, IFNγ, TGFβ, and IL-10 in murine macrophage cell lines und rut peritoneal macrophages
    • Chesrown SE, Monnier J, Visner G, Nick HS (1994) Regulation of inducible nitric oxide synthase mRNA levels by LPS, IFNγ, TGFβ, and IL-10 in murine macrophage cell lines und rut peritoneal macrophages. Biochem Biophys Res Commun 200:126-134
    • (1994) Biochem Biophys Res Commun , vol.200 , pp. 126-134
    • Chesrown, S.E.1    Monnier, J.2    Visner, G.3    Nick, H.S.4
  • 46
    • 0026529405 scopus 로고
    • IL-10 inhibits parasite killing and nitrogen oxide production by IFNγ-activated macrophages
    • Gazzinelli RT, Oswald IP, James SL, Sher A (1992) IL-10 inhibits parasite killing and nitrogen oxide production by IFNγ-activated macrophages. J Immunol 148:1792-1796
    • (1992) J Immunol , vol.148 , pp. 1792-1796
    • Gazzinelli, R.T.1    Oswald, I.P.2    James, S.L.3    Sher, A.4
  • 47
    • 0028297672 scopus 로고
    • Neutralization of IL-10 upregulates nitric oxide production and protects susceptible mice from challenge with Candida albicans
    • Romani L, Puccetti P, Menacci A, Cenci E, Spaccapelo R, Tonnetti L, Grohmann U, Bistoni F (1994) Neutralization of IL-10 upregulates nitric oxide production and protects susceptible mice from challenge with Candida albicans. J Immunol 152:3514-3521
    • (1994) J Immunol , vol.152 , pp. 3514-3521
    • Romani, L.1    Puccetti, P.2    Menacci, A.3    Cenci, E.4    Spaccapelo, R.5    Tonnetti, L.6    Grohmann, U.7    Bistoni, F.8
  • 48
    • 0026559756 scopus 로고
    • IL-10 synergizes with IL-4 and transforming growth factor-β to inhibit macrophage cytotoxic activity
    • Oswald IP, Gazzinelli RT, Sher A, James SL (1992) IL-10 synergizes with IL-4 and transforming growth factor-β to inhibit macrophage cytotoxic activity. J Immunol 148:3578-3582
    • (1992) J Immunol , vol.148 , pp. 3578-3582
    • Oswald, I.P.1    Gazzinelli, R.T.2    Sher, A.3    James, S.L.4
  • 49
    • 0026510069 scopus 로고
    • Interleukin-10 (IL-10) inhibits the induction of nitric oxide synthase by interferon-γ in murine macrophages
    • Cunha FQ, Moncada S, Liew FY (1992) Interleukin-10 (IL-10) inhibits the induction of nitric oxide synthase by interferon-γ in murine macrophages. Biochem Biophys Res Commun 182:1155-1159
    • (1992) Biochem Biophys Res Commun , vol.182 , pp. 1155-1159
    • Cunha, F.Q.1    Moncada, S.2    Liew, F.Y.3
  • 50
    • 0029034333 scopus 로고
    • Opposing effects of interleukin-10 on mouse macrophage functions
    • Appelberg R (1995) Opposing effects of interleukin-10 on mouse macrophage functions. Scand J Immunol 41:539-544
    • (1995) Scand J Immunol , vol.41 , pp. 539-544
    • Appelberg, R.1
  • 51
    • 0027197996 scopus 로고
    • Neuroprotective role of IL-4 against activated microglia
    • Chao CC, Molitor TW, Hu S (1993) Neuroprotective role of IL-4 against activated microglia. J Immunol 151:1473-1481
    • (1993) J Immunol , vol.151 , pp. 1473-1481
    • Chao, C.C.1    Molitor, T.W.2    Hu, S.3
  • 52
    • 0027980203 scopus 로고
    • Mechanisms of suppression of nitric oxide synthase expression by interleukin-4 in primary mouse macrophages
    • Bogdan C, Vodovotz Y, Paik J, Xie Q-W, Nathan C (1994) Mechanisms of suppression of nitric oxide synthase expression by interleukin-4 in primary mouse macrophages. J Leuko Biol 55:227-233
    • (1994) J Leuko Biol , vol.55 , pp. 227-233
    • Bogdan, C.1    Vodovotz, Y.2    Paik, J.3    Xie, Q.-W.4    Nathan, C.5
  • 54
    • 0026042191 scopus 로고
    • A possible novel pathway of regulation by murine T helper type-2 (Th2) cells of a Th1 cell activity via the modulation of the induction of nitric oxide synthase on macrophages
    • Liew FY, Li Y, Severn A, Millott S, Schmidt J, Salter M, Moncada S (1991) A possible novel pathway of regulation by murine T helper type-2 (Th2) cells of a Th1 cell activity via the modulation of the induction of nitric oxide synthase on macrophages. Eur J Immunol 21:2489-2494
    • (1991) Eur J Immunol , vol.21 , pp. 2489-2494
    • Liew, F.Y.1    Li, Y.2    Severn, A.3    Millott, S.4    Schmidt, J.5    Salter, M.6    Moncada, S.7
  • 55
    • 0026712298 scopus 로고
    • Immunosuppression induced by nitric oxide and its inhibition by interleukin-4
    • Al Ramadi BK, Meissler JJ, Huang D, Eisenstein TK (1992) Immunosuppression induced by nitric oxide and its inhibition by interleukin-4. Eur J Immunol 22:2249-2254
    • (1992) Eur J Immunol , vol.22 , pp. 2249-2254
    • Al Ramadi, B.K.1    Meissler, J.J.2    Huang, D.3    Eisenstein, T.K.4
  • 56
    • 0027991932 scopus 로고
    • Inhibition of nitric oxide synthase by interleukin-4 may involve inhibiting the activation of protein kinase C e
    • Sands WA, Bulut V, Severn A, Xu D, Liew FY (1994) Inhibition of nitric oxide synthase by interleukin-4 may involve inhibiting the activation of protein kinase C e. Eur J Immunol 24:2345-2350
    • (1994) Eur J Immunol , vol.24 , pp. 2345-2350
    • Sands, W.A.1    Bulut, V.2    Severn, A.3    Xu, D.4    Liew, F.Y.5
  • 57
    • 0027418013 scopus 로고
    • Immunovascular communication: Activation and deactivation of murine endothelial cell nitric oxide synthase by cytokines
    • Schneemann M, Schoedon G, Frei K, Schaffner A (1993) Immunovascular communication: activation and deactivation of murine endothelial cell nitric oxide synthase by cytokines. Immunol Lett 35:159-162
    • (1993) Immunol Lett , vol.35 , pp. 159-162
    • Schneemann, M.1    Schoedon, G.2    Frei, K.3    Schaffner, A.4
  • 58
    • 0026805989 scopus 로고
    • The microbicidal activity activity of interferon-γ-treated macrophages against Trypansoma cruzi involves L-arginine-dependent nitrogen-oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-β
    • Gazzinelli RT, Oswald IP, Hieny S, James SL, Sher A (1992) The microbicidal activity activity of interferon-γ-treated macrophages against Trypansoma cruzi involves L-arginine-dependent nitrogen-oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-β. Eur J Immunol 22:2501-2512
    • (1992) Eur J Immunol , vol.22 , pp. 2501-2512
    • Gazzinelli, R.T.1    Oswald, I.P.2    Hieny, S.3    James, S.L.4    Sher, A.5
  • 64
    • 0027968254 scopus 로고
    • Heterogeneous nitrite production by IL-4 stimulated human monocytes and peripheral blood mononucleur cells
    • Paul-Eugene N, Kolb JP, Damais C, Dugas B (1994) Heterogeneous nitrite production by IL-4 stimulated human monocytes and peripheral blood mononucleur cells. Immunol Lett 42:31-34
    • (1994) Immunol Lett , vol.42 , pp. 31-34
    • Paul-Eugene, N.1    Kolb, J.P.2    Damais, C.3    Dugas, B.4
  • 66
    • 0029064329 scopus 로고
    • Lead induces nitric oxide production in vitro by murine spenic macrophages
    • Tian L, Lawrence DA (1995) Lead induces nitric oxide production in vitro by murine spenic macrophages. Toxicol Appl Pharmacol 132:156-163
    • (1995) Toxicol Appl Pharmacol , vol.132 , pp. 156-163
    • Tian, L.1    Lawrence, D.A.2
  • 67
    • 0028948852 scopus 로고
    • Role of cyclic nucleotides and nitric oxide in blood mononucleur cell IgE production stimulated by IL-4
    • Paul-Eugene N, Pene J, Bousquet J, Dugas B (1995) Role of cyclic nucleotides and nitric oxide in blood mononucleur cell IgE production stimulated by IL-4. Cytokine 7:64-69
    • (1995) Cytokine , vol.7 , pp. 64-69
    • Paul-Eugene, N.1    Pene, J.2    Bousquet, J.3    Dugas, B.4
  • 68
    • 0028139055 scopus 로고
    • Regulatory role of nitric oxide in the IL-4-Induced IgE production by normal human peripheral blood mononuclear cells
    • Paul-Eugene N Kolb J-P, Damais C, Yamaoka K, Dugas B (1994) Regulatory role of nitric oxide in the IL-4-Induced IgE production by normal human peripheral blood mononuclear cells. Lymphokine Cytokine Res 13:287-293
    • (1994) Lymphokine Cytokine Res , vol.13 , pp. 287-293
    • Paul-Eugene, N.1    Kolb, J.-P.2    Damais, C.3    Yamaoka, K.4    Dugas, B.5
  • 70
    • 0029066664 scopus 로고
    • Nitric oxide synthesis in rat peritoneal macrophages is induced by IgE/DNP complexes and cyclic AMP analogues. Evidence in favor of a common signaling mechanism
    • Alonso A, Carvalho J, Alonso-Torre SR, Nunez L, Bosca L, Crespo M, S (1995) Nitric oxide synthesis in rat peritoneal macrophages is induced by IgE/DNP complexes and cyclic AMP analogues. Evidence in favor of a common signaling mechanism. J Immunol 154:6475-6483
    • (1995) J Immunol , vol.154 , pp. 6475-6483
    • Alonso, A.1    Carvalho, J.2    Alonso-Torre, S.R.3    Nunez, L.4    Bosca, L.5    Crespo, M.S.6
  • 71
    • 0027155514 scopus 로고
    • Norepinephrine suppresses inducible nitric oxide synthase activity in rat astroglial cultures
    • Feinstein DL, Galea E, Reis DJ (1993) Norepinephrine suppresses inducible nitric oxide synthase activity in rat astroglial cultures J Neurochem 60:1945-1948
    • (1993) J Neurochem , vol.60 , pp. 1945-1948
    • Feinstein, D.L.1    Galea, E.2    Reis, D.J.3
  • 72
    • 0027317414 scopus 로고
    • Nitric oxide production by murine macrophages is inhibited by prolonged elevation of cyclic AMP
    • Bulut V, Severn A, Liew FY (1993) Nitric oxide production by murine macrophages is inhibited by prolonged elevation of cyclic AMP. Biochem Biophys Res Comm 195:1134-1138
    • (1993) Biochem Biophys Res Comm , vol.195 , pp. 1134-1138
    • Bulut, V.1    Severn, A.2    Liew, F.Y.3
  • 73
    • 0026806044 scopus 로고
    • Modulation of the induction of nitric oxide synthase by eicosanoids in the murine macrophage cell line J774
    • Marotta P, Sautebin L, DiRosa M (1992) Modulation of the induction of nitric oxide synthase by eicosanoids in the murine macrophage cell line J774. Br J Pharmacol 107:640-641
    • (1992) Br J Pharmacol , vol.107 , pp. 640-641
    • Marotta, P.1    Sautebin, L.2    DiRosa, M.3
  • 74
    • 0027733724 scopus 로고
    • Pentoxifylline inhibits production of superoxide anion and tumor necrosis factor by kupffer cells in rat liver preservation
    • Kozaki K, Egawa H, Bernudes L, Feduska NJ, So S, Esquivel CO (1993) Pentoxifylline inhibits production of superoxide anion and tumor necrosis factor by kupffer cells in rat liver preservation. Transplant Proc 25:3025-3026
    • (1993) Transplant Proc , vol.25 , pp. 3025-3026
    • Kozaki, K.1    Egawa, H.2    Bernudes, L.3    Feduska, N.J.4    So, S.5    Esquivel, C.O.6
  • 76
    • 0027294597 scopus 로고
    • Pentoxifylline inhibits HIV-1 LTR-driven gene expression by blocking NF-κB action
    • Biswas DK, Dezube BJ, Ahlers CM, Pardee AB (1993) Pentoxifylline inhibits HIV-1 LTR-driven gene expression by blocking NF-κB action. J AIDS 6:778-786
    • (1993) J AIDS , vol.6 , pp. 778-786
    • Biswas, D.K.1    Dezube, B.J.2    Ahlers, C.M.3    Pardee, A.B.4
  • 79
    • 0027273042 scopus 로고
    • Phosphodiesterase inhibitor pentoxifylline, a selective suppressor of T helper type1 - But not type 2-associated lymphokine production, prevents induction of experimental autoimmune encephalomyelitis in Lewis rats
    • Rott O, Cash E, Fleischer B (1993) Phosphodiesterase inhibitor pentoxifylline, a selective suppressor of T helper type1 - but not type 2-associated lymphokine production, prevents induction of experimental autoimmune encephalomyelitis in Lewis rats. Eur J Immunol 23:1745-1751
    • (1993) Eur J Immunol , vol.23 , pp. 1745-1751
    • Rott, O.1    Cash, E.2    Fleischer, B.3
  • 80
    • 0027190721 scopus 로고
    • Activation of human peripheral blood mononuclear cells by nitric-oxide generating compounds
    • Lander HM, Sehajpal PK, Levine DM, Novogordsky A (1993) Activation of human peripheral blood mononuclear cells by nitric-oxide generating compounds. J Immunol 150: 1509-1516
    • (1993) J Immunol , vol.150 , pp. 1509-1516
    • Lander, H.M.1    Sehajpal, P.K.2    Levine, D.M.3    Novogordsky, A.4
  • 81
    • 0027133499 scopus 로고
    • Nitric oxide signaling: A possible role for G proteins
    • Lander HM, Sehajpal PK, Novogrodsky A (1993) Nitric oxide signaling: a possible role for G proteins. J Immunol 151: 7182-7187
    • (1993) J Immunol , vol.151 , pp. 7182-7187
    • Lander, H.M.1    Sehajpal, P.K.2    Novogrodsky, A.3
  • 82
    • 0026786241 scopus 로고
    • Nitric oxide modulation of human leukemia cell differentiation and gene expression
    • Magrinat G, Mason SN, Shami PJ, Weinberg JB (1992) Nitric oxide modulation of human leukemia cell differentiation and gene expression. Blood 80:1880-1884
    • (1992) Blood , vol.80 , pp. 1880-1884
    • Magrinat, G.1    Mason, S.N.2    Shami, P.J.3    Weinberg, J.B.4
  • 83
    • 0028903598 scopus 로고
    • Nitric oxide upregulates the release of inflammatory mediators by mouse macrophages
    • Marcinkiewicz J, Grabowska A, Chain B (1995) Nitric oxide upregulates the release of inflammatory mediators by mouse macrophages. Eur J Immunol 25:947-951
    • (1995) Eur J Immunol , vol.25 , pp. 947-951
    • Marcinkiewicz, J.1    Grabowska, A.2    Chain, B.3
  • 84
    • 0028881129 scopus 로고
    • Nitric oxide regulates 1L-8 expression in melanoma cells at the transcriptional level
    • Andrew PJ, Harant H, Lindley IJD (1995) Nitric oxide regulates 1L-8 expression in melanoma cells at the transcriptional level. Biochem Biophys Res Commun 214:949-956
    • (1995) Biochem Biophys Res Commun , vol.214 , pp. 949-956
    • Andrew, P.J.1    Harant, H.2    Lindley, I.J.D.3
  • 85
    • 0027442227 scopus 로고
    • Nitric oxide-releasing agents enhance cytokine-induced tumor necrosis factor synthesis in human mononuclear cells
    • Eigler A, Sinha B, Endres S (1993) Nitric oxide-releasing agents enhance cytokine-induced tumor necrosis factor synthesis in human mononuclear cells. Biochem Biophys Res Comm 196:494-501
    • (1993) Biochem Biophys Res Comm , vol.196 , pp. 494-501
    • Eigler, A.1    Sinha, B.2    Endres, S.3
  • 87
    • 0029011129 scopus 로고
    • Induction and stabilisation of IκBa by nitric oxide mediates inhibition of NF-κB
    • Peng H-B, Libby P, Liao JK (1995) Induction and stabilisation of IκBa by nitric oxide mediates inhibition of NF-κB. J Biol Chem 270:14214-14219
    • (1995) J Biol Chem , vol.270 , pp. 14214-14219
    • Peng, H.-B.1    Libby, P.2    Liao, J.K.3
  • 88
    • 0029159779 scopus 로고
    • Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
    • De Caterina R, Libby P, Peng H-B, Thannickal VJ, Rajavashisth TB, Gimbrone MA, Shin WS, Liao JK (1995) Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest 96:60-68
    • (1995) J Clin Invest , vol.96 , pp. 60-68
    • De Caterina, R.1    Libby, P.2    Peng, H.-B.3    Thannickal, V.J.4    Rajavashisth, T.B.5    Gimbrone, M.A.6    Shin, W.S.7    Liao, J.K.8
  • 90
    • 0028642293 scopus 로고
    • Physiological and pathophysiological roles of nitric oxide
    • Stewart AG, Phan LH, Grigoriadis G (1994) Physiological and pathophysiological roles of nitric oxide. Microsurg 15: 693-702
    • (1994) Microsurg , vol.15 , pp. 693-702
    • Stewart, A.G.1    Phan, L.H.2    Grigoriadis, G.3
  • 91
    • 0028952756 scopus 로고
    • Nitric oxide suppresses IFN- G production in the spleen of mercuric chloride-exposed brown Norway rats
    • Van der Meide PH, De Labie MCDC, Botman CAD, Aten J, Weening JJ (1995) Nitric oxide suppresses IFN- g production in the spleen of mercuric chloride-exposed brown Norway rats. Cell Immunol 161:195-206
    • (1995) Cell Immunol , vol.161 , pp. 195-206
    • Van Der Meide, P.H.1    De Labie, M.C.D.C.2    Botman, C.A.D.3    Aten, J.4    Weening, J.J.5
  • 92
    • 0029043151 scopus 로고
    • IL-1-induced nitric oxide inhibits chondrocyte proliferation via PGE2
    • Blanco FJ, Lotz M (1995) IL-1-induced nitric oxide inhibits chondrocyte proliferation via PGE2. Exp Cell Res 218: 319-325
    • (1995) Exp Cell Res , vol.218 , pp. 319-325
    • Blanco, F.J.1    Lotz, M.2
  • 94
    • 0029098769 scopus 로고
    • Natural resistance and nitric oxide
    • Nathan C (1995) Natural resistance and nitric oxide. Cell 82: 873-876
    • (1995) Cell , vol.82 , pp. 873-876
    • Nathan, C.1
  • 95
    • 0025731835 scopus 로고
    • Nitric oxide: An endogenous modulator of leukocyte adhesion
    • Kubes P, Suzuki M, Granger DN (1991) Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 88:4651-4654
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4651-4654
    • Kubes, P.1    Suzuki, M.2    Granger, D.N.3
  • 96
    • 0028243659 scopus 로고
    • Inhibition of macrophage Ia expression by nitric oxide
    • Sicher SC, Vazquez MA, Lu CY (1994) Inhibition of macrophage Ia expression by nitric oxide. J Immunol 153: 1293-1300
    • (1994) J Immunol , vol.153 , pp. 1293-1300
    • Sicher, S.C.1    Vazquez, M.A.2    Lu, C.Y.3
  • 97
    • 0026751291 scopus 로고
    • Elevated secretion of reactive nitrogen and oxygen intermediates by inflammatory leukocytes in hyperacute experimental autoimmune encephalitis: Enhancement by the soluble products of encephalitogenic T cells
    • MacMicking JD, Willenborg DO, Weidemann MJ, Rockett KA, Cowden WB (1992) Elevated secretion of reactive nitrogen and oxygen intermediates by inflammatory leukocytes in hyperacute experimental autoimmune encephalitis: enhancement by the soluble products of encephalitogenic T cells. J Exp Med 176:303-307
    • (1992) J Exp Med , vol.176 , pp. 303-307
    • MacMicking, J.D.1    Willenborg, D.O.2    Weidemann, M.J.3    Rockett, K.A.4    Cowden, W.B.5
  • 99
    • 0027197645 scopus 로고
    • Severity of neurologic signs and degree of inflammatory lesions in the brains of rats with Borna disease correlate with the induction of nitric oxide synthase
    • Zheng YM, Schäfer MK-H, Weihe E, Sheng H, Corisdeo S, Fu ZF, Koprowski H, Dietzschold B (1993) Severity of neurologic signs and degree of inflammatory lesions in the brains of rats with Borna disease correlate with the induction of nitric oxide synthase. J Virol 67:5786-5791
    • (1993) J Virol , vol.67 , pp. 5786-5791
    • Zheng, Y.M.1    Schäfer, M.K.-H.2    Weihe, E.3    Sheng, H.4    Corisdeo, S.5    Fu, Z.F.6    Koprowski, H.7    Dietzschold, B.8
  • 100
    • 0027220214 scopus 로고
    • Nitric oxide localized to spinal cords of mice with experimental allergic encephalitis: An electron paramagnetic resonance study
    • Lin RF, Lin T-S, Tilton RG, Cross AH (1993) Nitric oxide localized to spinal cords of mice with experimental allergic encephalitis: an electron paramagnetic resonance study. J Exp Med 178:643-648
    • (1993) J Exp Med , vol.178 , pp. 643-648
    • Lin, R.F.1    Lin, T.-S.2    Tilton, R.G.3    Cross, A.H.4
  • 102
    • 0026579380 scopus 로고
    • EPR evidence for nitric oxide production from guanidino nitrogens of L-arginine in animal tissues in vivo
    • Kubrina LN, Caldwell WS, Mordvintcev PI, Malenkova IV, Vanin AF (1992) EPR evidence for nitric oxide production from guanidino nitrogens of L-arginine in animal tissues in vivo. Biochem Biophys Acta 1099:233-237
    • (1992) Biochem Biophys Acta , vol.1099 , pp. 233-237
    • Kubrina, L.N.1    Caldwell, W.S.2    Mordvintcev, P.I.3    Malenkova, I.V.4    Vanin, A.F.5
  • 103
    • 0028360840 scopus 로고
    • Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalitis in SJL mice
    • Cross AH, Misko TP, Lin RF, Hickey WF, Trotter JL, Tilton RG (1994) Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalitis in SJL mice. J Clin Invest 93:2684-2690
    • (1994) J Clin Invest , vol.93 , pp. 2684-2690
    • Cross, A.H.1    Misko, T.P.2    Lin, R.F.3    Hickey, W.F.4    Trotter, J.L.5    Tilton, R.G.6
  • 104
    • 0028941990 scopus 로고
    • Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autoimmune encephalitis
    • Zielasek J, Jung S, Gold R, Liew FY, Toyka KV, Hartung HP (1995) Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autoimmune encephalitis. J Neuroimmunol 58:81-88.
    • (1995) J Neuroimmunol , vol.58 , pp. 81-88
    • Zielasek, J.1    Jung, S.2    Gold, R.3    Liew, F.Y.4    Toyka, K.V.5    Hartung, H.P.6
  • 106
    • 0029121001 scopus 로고
    • Potential role of nitric oxide in the pathophysiology of experimental bacterial meningitis in rats
    • Buster BL, Weintrob AC, Townsend GC, Scheid WM (1995) Potential role of nitric oxide in the pathophysiology of experimental bacterial meningitis in rats. Infect Immun 63: 3835-3839
    • (1995) Infect Immun , vol.63 , pp. 3835-3839
    • Buster, B.L.1    Weintrob, A.C.2    Townsend, G.C.3    Scheid, W.M.4
  • 107
    • 0028891365 scopus 로고
    • Inhibition of nitric oxide synthase partially attenuates alterations in the blood-cerebrospinal fluid barrier during experimental memningitis in rats
    • Boje KMK (1995) Inhibition of nitric oxide synthase partially attenuates alterations in the blood-cerebrospinal fluid barrier during experimental memningitis in rats Eur J Pharmacol 272:297-300
    • (1995) Eur J Pharmacol , vol.272 , pp. 297-300
    • Boje, K.M.K.1
  • 108
    • 0028803845 scopus 로고
    • An important role for the chemokine macrophage inflammatory protein-1a in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalitis
    • Karpus WJ, Lukacs NW, McRAe BL, Strieter RM, Kunkel SL, Miller SD (1995) An important role for the chemokine macrophage inflammatory protein-1a in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalitis. J Immunol 155:5003-5010
    • (1995) J Immunol , vol.155 , pp. 5003-5010
    • Karpus, W.J.1    Lukacs, N.W.2    McRae, B.L.3    Strieter, R.M.4    Kunkel, S.L.5    Miller, S.D.6
  • 109
    • 0030221758 scopus 로고    scopus 로고
    • Cytokines in inflammatory brain lesions: Helpful and harmful
    • Merrill JE, Benveniste EN (1996) Cytokines in inflammatory brain lesions: helpful and harmful. Trends Neurosci 19:331-338
    • (1996) Trends Neurosci , vol.19 , pp. 331-338
    • Merrill, J.E.1    Benveniste, E.N.2
  • 110
    • 0028061167 scopus 로고
    • Nitric oxide as a potential pathological mechanism in demyelination: Its differential effects on primary glial cells in vitro
    • Mitrovic B, Ignarro JL, Montestruque S, Smoll A, Merrill JE (1994) Nitric oxide as a potential pathological mechanism in demyelination: its differential effects on primary glial cells in vitro. Neurosci 61:575-585
    • (1994) Neurosci , vol.61 , pp. 575-585
    • Mitrovic, B.1    Ignarro, J.L.2    Montestruque, S.3    Smoll, A.4    Merrill, J.E.5
  • 113
    • 0029128265 scopus 로고
    • Inhibition of inducible nitric oxide synthase mRNA expression by basic fibroblast growth factor in human microglial cells
    • Colasanti M, Di Pucchio T, Perschini T, Sogos V, Preste M, Lauro G (1995) Inhibition of inducible nitric oxide synthase mRNA expression by basic fibroblast growth factor in human microglial cells. Neurosci Lett 195:45-48
    • (1995) Neurosci Lett , vol.195 , pp. 45-48
    • Colasanti, M.1    Di Pucchio, T.2    Perschini, T.3    Sogos, V.4    Preste, M.5    Lauro, G.6
  • 114
    • 0029438640 scopus 로고
    • A study on tumor necrosis factor, tumor necrosis factor receptors, and nitric oxide in human fetal glial cultures
    • St. Pierre BA, Granger DA, Wong J, Merrill JE (1995) A study on tumor necrosis factor, tumor necrosis factor receptors, and nitric oxide in human fetal glial cultures. Adv Pharmacol 34:415-438
    • (1995) Adv Pharmacol , vol.34 , pp. 415-438
    • St. Pierre, B.A.1    Granger, D.A.2    Wong, J.3    Merrill, J.E.4
  • 117
    • 0029143806 scopus 로고
    • Indirect evidence for nitric oxide involvment in multiple sclerosis by characterization of circulating antibodies directed against conjugated S-nitrocysteine
    • Boullerne AI, Petry KG, Meynard M, Geffard M (1995) Indirect evidence for nitric oxide involvment in multiple sclerosis by characterization of circulating antibodies directed against conjugated S-nitrocysteine. J Neuroimmunol 60:117-124
    • (1995) J Neuroimmunol , vol.60 , pp. 117-124
    • Boullerne, A.I.1    Petry, K.G.2    Meynard, M.3    Geffard, M.4
  • 122
    • 0026591114 scopus 로고
    • Different receptors mediate stimulation of nitric oxide-dependent cyclic GMP formation in neurons and astrocytes in culture
    • Agullo L, Garcia A (1992) Different receptors mediate stimulation of nitric oxide-dependent cyclic GMP formation in neurons and astrocytes in culture. Biochem Biophys Res Commun 182:1362-1368
    • (1992) Biochem Biophys Res Commun , vol.182 , pp. 1362-1368
    • Agullo, L.1    Garcia, A.2
  • 123
    • 0028835450 scopus 로고
    • Dexamethasone upregulates a constitutive nitric oxide synthase in cerebellar astrocytes but not in granule cells in culture
    • Baltrons MA, Agullo L, Garcia A (1995) Dexamethasone upregulates a constitutive nitric oxide synthase in cerebellar astrocytes but not in granule cells in culture. J Neurochem 654: 447-450
    • (1995) J Neurochem , vol.654 , pp. 447-450
    • Baltrons, M.A.1    Agullo, L.2    Garcia, A.3
  • 124
    • 0026774797 scopus 로고
    • Induction of nitric oxide synthase in glial cells
    • Simmons ML, Murphy S (1992) Induction of nitric oxide synthase in glial cells. J Neurochem 59:897-905
    • (1992) J Neurochem , vol.59 , pp. 897-905
    • Simmons, M.L.1    Murphy, S.2
  • 125
    • 0026486613 scopus 로고
    • Induction of calcium-independent nitricoxide synthase activity in primary rat glial cultures
    • Galea E, Feinstein DL, Reis DJ (1992) Induction of calcium-independent nitricoxide synthase activity in primary rat glial cultures. Proc Natl Acad Sci USA 89:10945-10949
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10945-10949
    • Galea, E.1    Feinstein, D.L.2    Reis, D.J.3
  • 126
    • 0028211176 scopus 로고
    • Cloning and expression of inducible nitric oxide synthase from rat astrocytes
    • Galea E, Reis DJ, Feinstein DL (1994) Cloning and expression of inducible nitric oxide synthase from rat astrocytes. J Neurosci Res 37:406-414
    • (1994) J Neurosci Res , vol.37 , pp. 406-414
    • Galea, E.1    Reis, D.J.2    Feinstein, D.L.3
  • 127
    • 0028145462 scopus 로고
    • Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes
    • Bolano JP, Peuchen S, Heales SJ, Land M, Clark JB (1994) Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes. J Neurochem 63:910-916
    • (1994) J Neurochem , vol.63 , pp. 910-916
    • Bolano, J.P.1    Peuchen, S.2    Heales, S.J.3    Land, M.4    Clark, J.B.5
  • 128
    • 0028089896 scopus 로고
    • Expression of inducible nitric oxide synthase causes delayed neurotoxicity in prmary mixed neuronal-glial cortical cultures
    • Dawson VL, Brahmbhatt HP, Mong JA, Dawson TM (1994) expression of inducible nitric oxide synthase causes delayed neurotoxicity in prmary mixed neuronal-glial cortical cultures. Neuropharmacol 33:1425-1430
    • (1994) Neuropharmacol , vol.33 , pp. 1425-1430
    • Dawson, V.L.1    Brahmbhatt, H.P.2    Mong, J.A.3    Dawson, T.M.4
  • 129
  • 130
    • 0029671449 scopus 로고    scopus 로고
    • S100 beta stimulates inducible nitric oxide synthase activity and mRNA levels in rat cortical astrocytes
    • Hu J, Castets F, Guevara JL, Vun-eldik L J (1996) S100 beta stimulates inducible nitric oxide synthase activity and mRNA levels in rat cortical astrocytes. J Biol Chem 271:2543-2547
    • (1996) J Biol Chem , vol.271 , pp. 2543-2547
    • Hu, J.1    Castets, F.2    Guevara, J.L.3    Vun-eldik, L.J.4
  • 132
    • 0029115029 scopus 로고
    • Parallel induction of nitric oxide amd tetrahydrobiopterin synthesis by cytokines in rat glial cells
    • Sakai N, Kaufman S, Milstien S (1995) Parallel induction of nitric oxide amd tetrahydrobiopterin synthesis by cytokines in rat glial cells. J Neurochem 65:895-902
    • (1995) J Neurochem , vol.65 , pp. 895-902
    • Sakai, N.1    Kaufman, S.2    Milstien, S.3
  • 133
    • 0029087650 scopus 로고
    • Microglial release of nitric oxide by the synergisit action of beta-amyloid and IFN-γ
    • Goodwill JL, Uemera E, Cunnick JE (1995) Microglial release of nitric oxide by the synergisit action of beta-amyloid and IFN-γ. Brain Res 692:207-214
    • (1995) Brain Res , vol.692 , pp. 207-214
    • Goodwill, J.L.1    Uemera, E.2    Cunnick, J.E.3
  • 134
    • 0027236605 scopus 로고
    • Cytokines regulate L-arginine-dependent cyclic GMP production in rat glial cells
    • Simmons ML, Murphy S (1993) Cytokines regulate L-arginine-dependent cyclic GMP production in rat glial cells. Eur J Neurosci 5:825-831
    • (1993) Eur J Neurosci , vol.5 , pp. 825-831
    • Simmons, M.L.1    Murphy, S.2
  • 136
    • 0028144361 scopus 로고
    • Nitric oxide synthase expression in glial cells: Suppression by tyrosine kinase inhibitors
    • Feinsten DL, Galea E, Cermak J, Chugh P, Lyandvert L, Reis DJ (1994) Nitric oxide synthase expression in glial cells: suppression by tyrosine kinase inhibitors. J Neurochem 62: 811-814
    • (1994) J Neurochem , vol.62 , pp. 811-814
    • Feinsten, D.L.1    Galea, E.2    Cermak, J.3    Chugh, P.4    Lyandvert, L.5    Reis, D.J.6
  • 137
    • 0028130266 scopus 로고
    • Duration of inducible nitric oxide synthase in glial cells
    • Park SK, Murphy S (1994) Duration of inducible nitric oxide synthase in glial cells. J Neurosci Res 39:405-411
    • (1994) J Neurosci Res , vol.39 , pp. 405-411
    • Park, S.K.1    Murphy, S.2
  • 138
    • 0027787430 scopus 로고
    • Interferon-γ and interleukin-1b induce nitric oxide formation from primary mouse astrocytes
    • Hewett SJ, Corbett JA, McDaniel ML, Choi DW (1993) Interferon-γ and interleukin-1b induce nitric oxide formation from primary mouse astrocytes. Neurosci Lett 164:229-232
    • (1993) Neurosci Lett , vol.164 , pp. 229-232
    • Hewett, S.J.1    Corbett, J.A.2    McDaniel, M.L.3    Choi, D.W.4
  • 139
    • 0027932457 scopus 로고
    • Selective potentiation of NMDA-induced neuronal injury folowing induction of astrocytic i-NOS
    • Hewett SJ, Csernansky CA, Choi DW (1994) Selective potentiation of NMDA-induced neuronal injury folowing induction of astrocytic i-NOS. Neuron 13:487-494
    • (1994) Neuron , vol.13 , pp. 487-494
    • Hewett, S.J.1    Csernansky, C.A.2    Choi, D.W.3
  • 140
    • 0026738695 scopus 로고
    • Activated microglia mediate neuronal injury via a nitric oxide mechanism
    • Chao CC, Hu S, Molitor TW, Shaskan EG, Peterson PK (1992) Activated microglia mediate neuronal injury via a nitric oxide mechanism. J Immunol 149:2736-2741
    • (1992) J Immunol , vol.149 , pp. 2736-2741
    • Chao, C.C.1    Hu, S.2    Molitor, T.W.3    Shaskan, E.G.4    Peterson, P.K.5
  • 142
    • 0028342494 scopus 로고
    • Nitric oxide production and neurotoxicity mediated by activated microglia from human versus mouse brain
    • Peterson PK, Hu S, Anderson WR, Chao CC (1994) Nitric oxide production and neurotoxicity mediated by activated microglia from human versus mouse brain J Infect Dis 170: 457-460
    • (1994) J Infect Dis , vol.170 , pp. 457-460
    • Peterson, P.K.1    Hu, S.2    Anderson, W.R.3    Chao, C.C.4
  • 144
    • 0028864234 scopus 로고
    • Human ramified microglial cells produce nitric oxide upon Escherichia coli lipopolysacharide and tumor necrosis factor alpha stimulation
    • Colasanti M, Persechini T, Di-Pucchio T, Gremo F, Lauro GM (1995) Human ramified microglial cells produce nitric oxide upon Escherichia coli lipopolysacharide and tumor necrosis factor alpha stimulation. Neurosci Lett 200:144-146
    • (1995) Neurosci Lett , vol.200 , pp. 144-146
    • Colasanti, M.1    Persechini, T.2    Di-Pucchio, T.3    Gremo, F.4    Lauro, G.M.5
  • 148
    • 0028016430 scopus 로고
    • Cloning and functional expression of human inducible nitric oxide synthase (NOS) cDNA from a glioblastoma cell line A-172
    • Hokari A, Zeniya M, Esumi H (1994) Cloning and functional expression of human inducible nitric oxide synthase (NOS) cDNA from a glioblastoma cell line A-172. J Biochem Tokyo 116:575-581
    • (1994) J Biochem Tokyo , vol.116 , pp. 575-581
    • Hokari, A.1    Zeniya, M.2    Esumi, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.