Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis

Journal of Neuroscience Research

Volumn 66, Issue 2, 2001, Pages 155-162

  Stanislaus, Romesh ^a   Singh, Avtar K ^b   Singh, Inderjit ^a,c  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

CNS; Cytokines; EAE; Lovastatin; Macrophages; Statins

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MEVINOLIN; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CELL MIGRATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; FEMALE; GENE EXPRESSION REGULATION; MACROPHAGE; MONONUCLEAR CELL; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL ADHESION; CHEMOTAXIS, LEUKOCYTE; CYTOKINES; DEMYELINATING DISEASES; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENDOTHELIUM, VASCULAR; ENZYME INDUCTION; FEMALE; GENE EXPRESSION REGULATION; INTERCELLULAR ADHESION MOLECULE-1; LOVASTATIN; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MONOCYTES; MULTIPLE SCLEROSIS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, INBRED LEW; SPINAL CORD;

EID: 0035888090     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.1207     Document Type: Article

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