메뉴 건너뛰기




Volumn 10, Issue 3, 2000, Pages 365-377

Axonal damage induced by invading T cells in organotypic central nervous system tissue in vitro: Involvement of microglial cells

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TUMOR NECROSIS FACTOR ALPHA;

EID: 0033917384     PISSN: 10156305     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2000.tb00268.x     Document Type: Article
Times cited : (60)

References (45)
  • 1
    • 0034651767 scopus 로고    scopus 로고
    • Functional maturation of adult mouse resting microglia into an APC is promoted by granulocyte-macrophage colony-stimulating factor and interaction with Th1 Cells
    • Aloisi F, De Simone R, Columba-Cabezas S, Penna G, Adorini L (2000) Functional maturation of adult mouse resting microglia into an APC is promoted by granulocyte-macrophage colony-stimulating factor and interaction with Th1 Cells. J Immunol 164: 1705-1712
    • (2000) J Immunol , vol.164 , pp. 1705-1712
    • Aloisi, F.1    De Simone, R.2    Columba-Cabezas, S.3    Penna, G.4    Adorini, L.5
  • 2
    • 0033370612 scopus 로고    scopus 로고
    • Relative efficiency of microglia, astrocytes, dendritic cells and B cells in naive CD4+ T cell priming and Th1/Th2 cell restimulation
    • Aloisi F, Ria F, Columba CS, Hess H, Penna G, Adorini L (1999) Relative efficiency of microglia, astrocytes, dendritic cells and B cells in naive CD4+ T cell priming and Th1/Th2 cell restimulation. Eur J Immunol 29: 2705-2714
    • (1999) Eur J Immunol , vol.29 , pp. 2705-2714
    • Aloisi, F.1    Ria, F.2    Columba, C.S.3    Hess, H.4    Penna, G.5    Adorini, L.6
  • 3
    • 0031172081 scopus 로고    scopus 로고
    • Astrocytes and microglial cells incorporate degenerating fibers following entorhinal lesion: A light, confocal, and electron microscopical study using a phagocytosis-dependent labeling technique
    • Bechmann I, Nitsch R (1997) Astrocytes and microglial cells incorporate degenerating fibers following entorhinal lesion: a light, confocal, and electron microscopical study using a phagocytosis-dependent labeling technique. Glia 20: 145-154
    • (1997) Glia , vol.20 , pp. 145-154
    • Bechmann, I.1    Nitsch, R.2
  • 4
    • 0030927653 scopus 로고    scopus 로고
    • Identification of phagocytic glial cells after lesion-induced anterograde degeneration using double-fluorescence labeling: Combination of axonal tracing and lectin or immunostaining
    • Bechmann I, Nitsch R (1997) Identification of phagocytic glial cells after lesion-induced anterograde degeneration using double-fluorescence labeling: combination of axonal tracing and lectin or immunostaining. Histochem Cell Biol 107: 391-397
    • (1997) Histochem Cell Biol , vol.107 , pp. 391-397
    • Bechmann, I.1    Nitsch, R.2
  • 5
    • 0031950030 scopus 로고    scopus 로고
    • The perforant path projection from the medial entorhinal cortex layer III to the subiculum in the rat combined hippocampal-entorhinal cortex slice
    • Behr J, Gloveli T, Heinemann U (1998) The perforant path projection from the medial entorhinal cortex layer III to the subiculum in the rat combined hippocampal-entorhinal cortex slice. Eur J Neurosci 10:1011-1018
    • (1998) Eur J Neurosci , vol.10 , pp. 1011-1018
    • Behr, J.1    Gloveli, T.2    Heinemann, U.3
  • 6
    • 0025033649 scopus 로고
    • Cellular immune response in multiple sclerosis plaques
    • Boyle EA, McGeer PL (1990) Cellular immune response in multiple sclerosis plaques. Am J Pathol 137: 575-584
    • (1990) Am J Pathol , vol.137 , pp. 575-584
    • Boyle, E.A.1    McGeer, P.L.2
  • 8
    • 0031985336 scopus 로고    scopus 로고
    • Mature microglia resemble immature antigen-presenting cells
    • Carson MJ, Reilly CR, Sutcliffe JG, Lo D (1998) Mature microglia resemble immature antigen-presenting cells. Glia 22: 72-85
    • (1998) Glia , vol.22 , pp. 72-85
    • Carson, M.J.1    Reilly, C.R.2    Sutcliffe, J.G.3    Lo, D.4
  • 9
    • 0032925357 scopus 로고    scopus 로고
    • Microglia stimulate naive T-cell differentiation without stimulating T-cell proliferation
    • Carson MJ, Sutcliffe JG, Campbell IL (1999) Microglia stimulate naive T-cell differentiation without stimulating T-cell proliferation. J Neurosci Res 55: 127-134
    • (1999) J Neurosci Res , vol.55 , pp. 127-134
    • Carson, M.J.1    Sutcliffe, J.G.2    Campbell, I.L.3
  • 10
    • 0027970495 scopus 로고
    • Microglial cells qualify as the stimulators of unprimed CD4+ and CD8+ T lymphocytes in the central nervous system
    • Cash E, Rott O (1994) Microglial cells qualify as the stimulators of unprimed CD4+ and CD8+ T lymphocytes in the central nervous system. Clin Exp Immunol 98: 313-318
    • (1994) Clin Exp Immunol , vol.98 , pp. 313-318
    • Cash, E.1    Rott, O.2
  • 11
    • 0030811129 scopus 로고    scopus 로고
    • Microglial production of TNF-alpha is induced by activated T lymphocytes. Involvement of VLA-4 and inhibition by interferonbeta-1b
    • Chabot S, Williams G, Yong VW (1997) Microglial production of TNF-alpha is induced by activated T lymphocytes. Involvement of VLA-4 and inhibition by interferonbeta-1b. J Clin Invest 100: 604-6-12
    • (1997) J Clin Invest , vol.100 , pp. 604-612
    • Chabot, S.1    Williams, G.2    Yong, V.W.3
  • 12
    • 0029565567 scopus 로고
    • Persistent functional deficit in multiple sclerosis and autosomal dominant cerebellar ataxia is associated with axon loss
    • Davie CA, Barker GJ, Webb S, Tofts PS, Thompson AJ, Harding AE, McDonald WI, Miller DH (1995) Persistent functional deficit in multiple sclerosis and autosomal dominant cerebellar ataxia is associated with axon loss. Brain 118: 1583-1592
    • (1995) Brain , vol.118 , pp. 1583-1592
    • Davie, C.A.1    Barker, G.J.2    Webb, S.3    Tofts, P.S.4    Thompson, A.J.5    Harding, A.E.6    McDonald, W.I.7    Miller, D.H.8
  • 13
    • 0028722028 scopus 로고
    • The organotypic entorhinal-hippocampal complex slice culture of adolescent rats. A model to study transcellular changes in a circuit particularly vulnerable in neurodegenerative disorders
    • Diekmann S, Nitsch R, Ohm TG (1994) The organotypic entorhinal-hippocampal complex slice culture of adolescent rats. A model to study transcellular changes in a circuit particularly vulnerable in neurodegenerative disorders. J Neural Transm Suppl 44: 61-71
    • (1994) J Neural Transm Suppl , vol.44 , pp. 61-71
    • Diekmann, S.1    Nitsch, R.2    Ohm, T.G.3
  • 14
    • 0030587789 scopus 로고    scopus 로고
    • Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals
    • Dubey C, Croft M, Swain SL (1996) Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals. J Immunol 157: 3280-3289
    • (1996) J Immunol , vol.157 , pp. 3280-3289
    • Dubey, C.1    Croft, M.2    Swain, S.L.3
  • 16
    • 0030763726 scopus 로고    scopus 로고
    • Adhesion molecule expression on phagocytic microglial cells following anterograde degeneration of perforant path axons
    • Hailer NP, Bechmann I, Heizmann S, Nitsch R (1997) Adhesion molecule expression on phagocytic microglial cells following anterograde degeneration of perforant path axons. Hippocampus 7: 341-349
    • (1997) Hippocampus , vol.7 , pp. 341-349
    • Hailer, N.P.1    Bechmann, I.2    Heizmann, S.3    Nitsch, R.4
  • 17
    • 0030887990 scopus 로고    scopus 로고
    • Fluorescent dye prelabelled microglial cells migrate into organotypic hippocampal slice cultures and ramify
    • Hailer NP, Heppner FL, Haas D, Nitsch R (1997) Fluorescent dye prelabelled microglial cells migrate into organotypic hippocampal slice cultures and ramify. Eur J Neurosci 9: 863-866
    • (1997) Eur J Neurosci , vol.9 , pp. 863-866
    • Hailer, N.P.1    Heppner, F.L.2    Haas, D.3    Nitsch, R.4
  • 18
    • 0030447438 scopus 로고    scopus 로고
    • Resting microglial cells in vitro: Analysis of morphology and adhesion molecule expression in organotypic hippocampal slice cultures
    • Hailer NP, Järhult JD, Nitsch R (1996) Resting microglial cells in vitro: analysis of morphology and adhesion molecule expression in organotypic hippocampal slice cultures. Glia 18: 319-331
    • (1996) Glia , vol.18 , pp. 319-331
    • Hailer, N.P.1    Järhult, J.D.2    Nitsch, R.3
  • 19
    • 0032428177 scopus 로고    scopus 로고
    • Activated microglial cells migrate towards sites of excitotoxic neuronal injury inside organotypic hippocampal slice cultures
    • Heppner FL, Skutella T, Hailer NP, Nitsch R (1998) Activated microglial cells migrate towards sites of excitotoxic neuronal injury inside organotypic hippocampal slice cultures. Eur J Neurosci 10: 3284-3290
    • (1998) Eur J Neurosci , vol.10 , pp. 3284-3290
    • Heppner, F.L.1    Skutella, T.2    Hailer, N.P.3    Nitsch, R.4
  • 20
    • 0030989875 scopus 로고    scopus 로고
    • Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives
    • Hohlfeld R (1997) Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives. Brain 120: 865-916
    • (1997) Brain , vol.120 , pp. 865-916
    • Hohlfeld, R.1
  • 22
  • 23
    • 0022591581 scopus 로고
    • Immunohistochemical analysis of the rat central nervous system during experimental allergic encephalomyelitis, with special reference to la-positive cells with dendritic morphology
    • Matsumoto Y, Hara N, Tanaka R, Fujiwara M (1986) Immunohistochemical analysis of the rat central nervous system during experimental allergic encephalomyelitis, with special reference to la-positive cells with dendritic morphology. J Immunol 136: 3668-3676
    • (1986) J Immunol , vol.136 , pp. 3668-3676
    • Matsumoto, Y.1    Hara, N.2    Tanaka, R.3    Fujiwara, M.4
  • 24
    • 0028021571 scopus 로고
    • Neuroimmune mechanisms in Alzheimer disease pathogenesis
    • McGeer PL, Rogers J, McGeer EG (1994) Neuroimmune mechanisms in Alzheimer disease pathogenesis [see comments]. Alzheimer Dis Assoc Disord 8: 149-158
    • (1994) Alzheimer Dis Assoc Disord , vol.8 , pp. 149-158
    • McGeer, P.L.1    Rogers, J.2    McGeer, E.G.3
  • 25
    • 0028950550 scopus 로고
    • Class II MHC gene expression in microglia. Regulation by the cytokines IFN-gamma, TNF-alpha, and TGF-beta
    • Panek RB, Benveniste EN (1995) Class II MHC gene expression in microglia. Regulation by the cytokines IFN-gamma, TNF-alpha, and TGF-beta. J Immunol 154:2846-2854
    • (1995) J Immunol , vol.154 , pp. 2846-2854
    • Panek, R.B.1    Benveniste, E.N.2
  • 26
    • 0345294457 scopus 로고    scopus 로고
    • A revised view of the central nervous system microenvironment and major histocompatibility complex class II antigen presentation
    • Perry VH (1998) A revised view of the central nervous system microenvironment and major histocompatibility complex class II antigen presentation. J Neuroimmunol 90: 113-121
    • (1998) J Neuroimmunol , vol.90 , pp. 113-121
    • Perry, V.H.1
  • 27
    • 0028983573 scopus 로고
    • TNF-alpha expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines
    • Renno T, Krakowski M, Piccirillo C, Lin JY, Owens T (1995) TNF-alpha expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines. J Immunol 154: 944-953
    • (1995) J Immunol , vol.154 , pp. 944-953
    • Renno, T.1    Krakowski, M.2    Piccirillo, C.3    Lin, J.Y.4    Owens, T.5
  • 29
    • 0032103936 scopus 로고    scopus 로고
    • Central nervous system microglial cell activation and proliferation follows direct interaction with tissue-infiltrating T cell blasts
    • Sedgwick JD, Ford AL, Foulcher E, Airriess R (1998) Central nervous system microglial cell activation and proliferation follows direct interaction with tissue-infiltrating T cell blasts. J Immunol 160: 5320-5330
    • (1998) J Immunol , vol.160 , pp. 5320-5330
    • Sedgwick, J.D.1    Ford, A.L.2    Foulcher, E.3    Airriess, R.4
  • 30
    • 0025852567 scopus 로고
    • Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions
    • Selmaj K, Raine CS, Cannella B, Brosnan CF (1991) Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin Invest 87: 949-954
    • (1991) J Clin Invest , vol.87 , pp. 949-954
    • Selmaj, K.1    Raine, C.S.2    Cannella, B.3    Brosnan, C.F.4
  • 31
    • 0023904746 scopus 로고
    • Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro
    • Selmaj KW, Raine CS (1988) Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann Neurol 23: 339-346
    • (1988) Ann Neurol , vol.23 , pp. 339-346
    • Selmaj, K.W.1    Raine, C.S.2
  • 32
    • 0031863689 scopus 로고    scopus 로고
    • Neuronal apoptosis induced by HIV-1 Tat protein and TNF-alpha: Potentiation of neurotoxicity mediated by oxidative stress and implications for HIV-1 dementia
    • Shi B, Raina J, Lorenzo A, Busciglio J, Gabuzda D (1998) Neuronal apoptosis induced by HIV-1 Tat protein and TNF-alpha: potentiation of neurotoxicity mediated by oxidative stress and implications for HIV-1 dementia. J Neurovirol 4: 281-290
    • (1998) J Neurovirol , vol.4 , pp. 281-290
    • Shi, B.1    Raina, J.2    Lorenzo, A.3    Busciglio, J.4    Gabuzda, D.5
  • 33
    • 0029965137 scopus 로고    scopus 로고
    • A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: A tale of smart bombs and the infantry
    • Steinman L (1996) A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: a tale of smart bombs and the infantry. Proc Natl Acad Sci USA 93: 2253-2256
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2253-2256
    • Steinman, L.1
  • 34
    • 0027356664 scopus 로고
    • Heterogeneity of microglial and perivascular cell populations: Insights gained from the facial nucleus paradigm
    • Streit WJ, Graeber MB (1993) Heterogeneity of microglial and perivascular cell populations: insights gained from the facial nucleus paradigm. Glia 7: 68-74
    • (1993) Glia , vol.7 , pp. 68-74
    • Streit, W.J.1    Graeber, M.B.2
  • 35
    • 0025077080 scopus 로고
    • Molecular, cellular, and pathologic characterization of HLA-DR immunoreactivity in normal elderly and Alzheimer's disease brain
    • Styren SD, Civin WH, Rogers J (1990) Molecular, cellular, and pathologic characterization of HLA-DR immunoreactivity in normal elderly and Alzheimer's disease brain. Exp Neurol 110: 93-104
    • (1990) Exp Neurol , vol.110 , pp. 93-104
    • Styren, S.D.1    Civin, W.H.2    Rogers, J.3
  • 36
    • 0025732220 scopus 로고
    • Specific transcellular carbocyanine-labelling of rat retinal microgl a during injury-induced neuronal degeneration
    • Thanos S (1991) Specific transcellular carbocyanine-labelling of rat retinal microgl a during injury-induced neuronal degeneration. Neurosci Lett 127: 108-112
    • (1991) Neurosci Lett , vol.127 , pp. 108-112
    • Thanos, S.1
  • 37
    • 0012205849 scopus 로고
    • Old dyes for new scopes: The phagocytosis-dependent long-term fluorescence labelling of microglial cells in vivo
    • Thanos S, Kacza J, Seeger J, Mey J (1994) Old dyes for new scopes: the phagocytosis-dependent long-term fluorescence labelling of microglial cells in vivo. Trends Neurosci 17: 177-182
    • (1994) Trends Neurosci , vol.17 , pp. 177-182
    • Thanos, S.1    Kacza, J.2    Seeger, J.3    Mey, J.4
  • 38
    • 0032193213 scopus 로고    scopus 로고
    • Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice
    • Iran EH, Hoekstra K, van Rooijen N, Dijkstra CD, Owens T (1998) Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice. J Immunol 161: 3767-3775
    • (1998) J Immunol , vol.161 , pp. 3767-3775
    • Iran, E.H.1    Hoekstra, K.2    Van Rooijen, N.3    Dijkstra, C.D.4    Owens, T.5
  • 40
    • 0032796747 scopus 로고    scopus 로고
    • Axonal pathology in multiple sclerosis: Relationship to neurological disability
    • Trapp BD, Ransohoff R, Rudick R (1999) Axonal pathology in multiple sclerosis: relationship to neurological disability. Curr Opin Neurol 12: 295-302
    • (1999) Curr Opin Neurol , vol.12 , pp. 295-302
    • Trapp, B.D.1    Ransohoff, R.2    Rudick, R.3
  • 41
    • 0032915309 scopus 로고    scopus 로고
    • Neurodegeneration in multiple sclerosis: Relationship to neurological disability
    • Trapp BD, Ransohoff RM, Fisher E, Rudick RA (1999) Neurodegeneration in multiple sclerosis: relationship to neurological disability. Neuroscientist 5: 48-57
    • (1999) Neuroscientist , vol.5 , pp. 48-57
    • Trapp, B.D.1    Ransohoff, R.M.2    Fisher, E.3    Rudick, R.A.4
  • 42
    • 0025942859 scopus 로고
    • Analysis of T cell stimulation by superantigen plus major hislocompatibility complex class II molecules or by CD3 monoclonal antibody: Costimulation by purified adhesion ligands VCAM-1, ICAM-1, but not ELAM-1
    • van Seventer GA, Newman W, Shimizu Y, Nutman TB, Tanaka Y, Horgan KJ, Gopal TV, Ennis E, O'Sullivan D, Grey H, et al (1991) Analysis of T cell stimulation by superantigen plus major hislocompatibility complex class II molecules or by CD3 monoclonal antibody: costimulation by purified adhesion ligands VCAM-1, ICAM-1, but not ELAM-1. J Exp Med 174: 901-913
    • (1991) J Exp Med , vol.174 , pp. 901-913
    • Van Seventer, G.A.1    Newman, W.2    Shimizu, Y.3    Nutman, T.B.4    Tanaka, Y.5    Horgan, K.J.6    Gopal, T.V.7    Ennis, E.8    O'Sullivan, D.9    Grey, H.10
  • 45
    • 0022644493 scopus 로고
    • Immunocytochemical characterisation of the immune reaction in the central nervous system in multiple sclerosis. Possible role for microglia in lesion growth
    • Woodroofe MN, Bellamy AS, Feldmann M, Davison AN, Cuzner ML (1986) Immunocytochemical characterisation of the immune reaction in the central nervous system in multiple sclerosis. Possible role for microglia in lesion growth. J Neurol Sci 74: 135-152
    • (1986) J Neurol Sci , vol.74 , pp. 135-152
    • Woodroofe, M.N.1    Bellamy, A.S.2    Feldmann, M.3    Davison, A.N.4    Cuzner, M.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.