1,25-Dihydroxyvitamin D3 treatment decreases macrophage accumulation in the CNS of mice with experimental autoimmune encephalomyelitis

Journal of Neuroimmunology

Volumn 103, Issue 2, 2000, Pages 171-179

  Nashold, Faye E ^a   Miller, David J ^b   Hayes, Colleen E ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b University of Wisconsin Health   (United States)

Author keywords

Autoimmunity; EAE; Macrophages; Multiple sclerosis; Vitamin D

Indexed keywords

CALCITRIOL;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; INFLAMMATION; MACROPHAGE; MENINGITIS; MICROGLIA; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD; T LYMPHOCYTE;

ANIMALS; APOPTOSIS; B-LYMPHOCYTES; CALCITRIOL; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL COUNT; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; FLOW CYTOMETRY; HINDLIMB; LYMPH NODES; MACROPHAGE-1 ANTIGEN; MACROPHAGES; MALE; MICE; PARALYSIS; SPINAL CORD;

EID: 0033965231     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(99)00247-7     Document Type: Article

References (46)

1. Acheson E.D., Bachrach C.A., Wright F.M. Some comments on the relationship of the distribution of multiple sclerosis to latitude, solar radiation and other variables. Acta Psychiatr. Scand. 35:1960;132-147. Suppl. 147.
2. Bauer J., Huitinga I., Zhao W., Lassmann H., Hickey W.F., Kijkstra C.D. The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis. Glia. 15:1995;437-446.
3. Bellingan G.J., Caldwell H., Howie S.E.M., Dransfield I., Haslett C. In vivo fate of the inflammatory macrophage during the resolution of inflammation. J. Immunol. 157:1996;2577-2585.
4. Benveniste E.N. Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis. J. Mol. Med. 75:1997;165-173.
5. 3 in human peripheral blood mononuclear cells: presence in monocytes and induction in T lymphocytes following activation. J. Clin. Endocrinol. Metab. 570:1983;1308-1310.
6. 3. J. Neuroimmunol. 61:1995;151-160.
7. 3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis. Proc. Natl. Acad. Sci. U.S.A. 93:1996;7861-7864.
8. 3 is a positive regulator for the two anti-encephalitogenic cytokines TGF-β1 and IL-4. J. Immunol. 160:1998;5314-5319.
9. Cobbold S., Waldmann H. Infectious tolerance. Curr. Opin. Immunol. 10:1998;518-524.
10. Cosman F., Nieves J., Komar L., Ferrer G., Herbert J., Formica C., Shen V., Lindsay R. Fracture history and bone loss in patients with MS. Neurology. 51:1998;1161-1165.
11. Diebler G.E., Martenson R.E., Kies M.W. Large scale preparation of myelin basic protein from central nervous tissue of several mammalian species. Prep. Biochem. 2:1972;139-165.
12. Ebers G.C., Sadovnick A.D. The role of genetic factors in multiple sclerosis susceptibility. J. Neuroimmunol. 54:1994;1-17.
13. Gehrmann J., Matsumoto Y., Kreutzberg G.W. Microglia: intrinsic immuneffector cell of the brain. Brain Res. Rev. 20:1995;269-287.
14. Glabinski A.R., Tani M., Strieter R.M., Tuohy V.K., Ransohoff R.M. Synchronous synthesis of α- and β-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis. Am. J. Pathol. 150:1998;617-630.
15. Goldberg P. Multiple sclerosis: vitamin D and calcium as environmental determinants of prevalence (A viewpoint): Part 1. Sunlight, dietary factors and epidemiology. Int. J. Environ. Stud. 6:1974;19-27.
16. Gordon E.J., Myers K.J., Dougherty J.P., Rosen H., Ron Y. Both anti-CD11a (LFA-1) and anti-CD11b (Mac-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis. J. Neuroimmunol. 62:1995;153-160.
17. Griffiths I.R., Duncan I.D., McCulloch M. Shaking pups: a disorder of central myelination in the spaniel dog: II. Ultrastructural observations on the white matter of the cervical spinal cord. Journal of Neurocytology. 10:1981;847-858.
18. Haussler M.R., Haussler C.A., Jurutka P.W., Thompson P.D., Hsieh J.C., Remus L.S., Selznick S.H., Whitfield G.K. The vitamin D hormone and its nuclear receptor: molecular actions and disease states. J. Endocrinol. 154:1997;557-573.
19. Hayes C.E., Cantorna M.T., DeLuca H.F. Vitamin D and multiple sclerosis. Proc. Soc. Exp. Biol. Med. 216:1997;21-27.
20. Holick M.F. Environmental factors that influence the cutaneous production of vitamin D. Am. J. Clin. Nutr. 61:1995;638S-645S. suppl.
21. Huitinga I., van Rooijen N., de Groot C.J.A., Uitdehaag B.M.J., Diikstra C.D. Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages. J. Exp. Med. 172:1990;1025-1033.
22. Karpus W.J., Lukacs N.W., McRae B.L., Strieter R.M., Kunkel S.L., Miller S.D. An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis. J. Immunol. 155:1995;5003-5010.
23. Kurtzke J.F. On the fine structure of the distribution of multiple sclerosis. Acta Neurol. Scand. 43:1976;257-282.
24. Lawson L.J., Perry V.H., Gordon S. Turnover of resident microglia in the normal adult mouse brain. Neuroscience. 48:1992;405-415.
25. 3 suppresses the in vivo induction of murine experimental autoimmune encephalomyelitis. J. Clin. Invest. 87:1991;1103-1107.
26. Lieb E. Erichrome (solochrome cyanine RS): a superior substitute for hematoxylin in nuclear and myelin sheath staining techniques. Lab. Med. 9:1978;13.
27. Mcmanus C., Berman J.W., Brett F.M., Staunton H., Farrell M., Brosnan C.F. MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions - an immunohistochemical and in situ hybridization study. J. Neuroimmunol. 86:1998;20-29.
28. Miller D.J., Hayes C.E. Phenotypic and genetic characterization of a unique B lymphocyte deficiency in strain A/WySnJ mice. Eur. J. Immunol. 21:1991;1123-1130.
29. Miller D.J., Rodriguez M. Spontaneous central nervous system remyelination in strain A mice after infection with the Daniel's (DA) strain of Theiler's virus. Acta Neuropathologica. 91:1996;559-595.
30. Miller D.J., Njenga M.K., Murray P.D., Leibowitz J., Rodriguez M. A monoclonal natural autoantibody that promotes remyelination suppresses central nervous system inflammation and increases virus expression after Theiler's virus-induced demyelination. Int. Immunol. 8:1996;131-141.
31. Miller D.J., Bright J.J., Sriram S., Rodriguez M. Successful treatment of established chronic relapsing experimental autoimmune encephalomyelitis in mice with a monoclonal natural autoantibody. J. Neuroimmunol. 75:1997;204-209.
32. Nieves J., Cosman F., Herbert J., Shen V., Lindsay R. High prevalence of vitamin D deficiency and reduced bone mass in multiple sclerosis. Neurology. 44:1994;1687-1692.
33. Parkinson J.F., Mitrovic B., Merrill J.E. The role of nitric oxide in multiple sclerosis. J. Mol. Med. 75:1997;174-186.
34. Pierce M., Rodriguez M. Erichrome stain for myelin on osmicated tissue embedded in glycol methacrylate plastic. J. Histotechnol. 12:1989;35-36.
35. Pope J.G., Karpus W.J., VanderLugt C., Miller S.D. Flow cytometric and functional analyses of central nervous system-infiltrating cells in SJL/J mice with Theiler's virus-induced demyelinating disease. J. Immunol. 156:1996;4050-4058.
36. Presthus J. Report on the multiple sclerosis investigations in West Norway. Acta Psychiatr. Neurol. Scand., Suppl. 147:1960;88-92.
37. 3 receptors in human leukocytes. Science. 221:1983;1181-1183.
38. Rodriguez M., Leibowitz J., David C.S. Susceptibility to Theiler's virus-induced demyelination: Mapping of the gene within the H-2D region. J. Exp. Med. 163:1986;620-631.
39. Schefler, W.C., 1979. Statistics for the Biological Sciences, 2nd edn. Addison-Wesley Publishing, Reading, MA, pp. 214-216.
40. Simpson J.E., Newcombe J., Cuzner M.L., Woodroofe M.N. Expression of monocyte chemoattractant protein-1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions. J. Neuroimmunol. 84:1998;238-249.
41. Smith S.M., Hayes C.E. Contrasting impairments in IgM and IgG responses in vitamin A-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 84:1987;5878-5882.
42. Springer T.A. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 76:1994;301-314.
43. Steinman L. Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell. 85:1996;299-302.
44. Tran E.H., Hoekstra K., van Rooijen N., Dijkstra C.D., Owens T. Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice. J. Immunol. 161:1998;3767-3775.
45. Ulvestad E., Williams K., Bjerkvig R., Tiekotter K., Antel J., Matre R. Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen-presenting cells. J. Leukocyte Biol. 56:1994;732-740.
46. Westlund K. Distribution and mortality time trend of multiple sclerosis and some other diseases of Norway. Acta Neurol. Scand. 46:1970;455-483.