-
1
-
-
0029584276
-
Substrates of human hepatic cytochrome P450 3A4
-
Li AP, Kaminski DL, Rasmussen A. Substrates of human hepatic cytochrome P450 3A4. Toxicology. 1995;104:1-8.
-
(1995)
Toxicology
, vol.104
, pp. 1-8
-
-
Li, A.P.1
Kaminski, D.L.2
Rasmussen, A.3
-
2
-
-
0033569516
-
Pharmacogenomics: Translating functional genomics into rational therapeutics
-
Evans WE, Relling MV. Pharmacogenomics: translating functional genomics into rational therapeutics. Science. 1999;286:487-491.
-
(1999)
Science
, vol.286
, pp. 487-491
-
-
Evans, W.E.1
Relling, M.V.2
-
3
-
-
0031748173
-
In vitro and in vivo drug interactions involving human CYP3A
-
Thummel KE, Wilkinson GR. In vitro and in vivo drug interactions involving human CYP3A. Annu Rev Pharmacol Toxicol. 1998;38:389-430.
-
(1998)
Annu Rev Pharmacol Toxicol
, vol.38
, pp. 389-430
-
-
Thummel, K.E.1
Wilkinson, G.R.2
-
4
-
-
0030627336
-
Role of cytochrome P450 enzymes in drug-drug interactions
-
Guengerich FP. Role of cytochrome P450 enzymes in drug-drug interactions. Adv Pharmacol. 1997;43:7-35.
-
(1997)
Adv Pharmacol
, vol.43
, pp. 7-35
-
-
Guengerich, F.P.1
-
5
-
-
0030428256
-
Cytochrome P4503A (CYP3A) metabolism: Prediction of in vivo activity in humans
-
Wilkinson GR. Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans. J Pharmacokinet Biopharm. 1996;24:475-490.
-
(1996)
J Pharmacokinet Biopharm
, vol.24
, pp. 475-490
-
-
Wilkinson, G.R.1
-
6
-
-
0033973926
-
Influence of dietary components on the gastrointestinal metabolism and transport of drugs
-
Evans AM. Influence of dietary components on the gastrointestinal metabolism and transport of drugs. Ther Drug Monit. 2000;22:131-136.
-
(2000)
Ther Drug Monit
, vol.22
, pp. 131-136
-
-
Evans, A.M.1
-
7
-
-
0000783041
-
Evaluation of the genetic component of variability in CYP3A4 activity: A repeated drug administration method
-
Ozdemir V, Kalowa W, Tang BK, et al. Evaluation of the genetic component of variability in CYP3A4 activity: a repeated drug administration method. Pharmacogenetics. 2000;10:373-388.
-
(2000)
Pharmacogenetics
, vol.10
, pp. 373-388
-
-
Ozdemir, V.1
Kalowa, W.2
Tang, B.K.3
-
8
-
-
0036515846
-
Receptor-dependent transcriptional activation of cytochrome P4503A genes: Induction mechanisms, species differences and interindividual variation in man
-
Gibson GG, Plant NJ, Swales KE, et al. Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man. Xenobiotica. 2002;32:165-206.
-
(2002)
Xenobiotica
, vol.32
, pp. 165-206
-
-
Gibson, G.G.1
Plant, N.J.2
Swales, K.E.3
-
9
-
-
0021361026
-
Induction of cytochrome P-450 by glucocorticoids in rat liver. II. Evidence that glucocorticoids regulate induction of cytochrome P-450 by a nonclassical receptor mechanism
-
Schuetz EG, Guzelian PS. Induction of cytochrome P-450 by glucocorticoids in rat liver. II. Evidence that glucocorticoids regulate induction of cytochrome P-450 by a nonclassical receptor mechanism. J Biol Chem. 1984;259:2007-2012.
-
(1984)
J Biol Chem
, vol.259
, pp. 2007-2012
-
-
Schuetz, E.G.1
Guzelian, P.S.2
-
10
-
-
0026464616
-
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
-
Kolars JC, Schmiedlin-Ren P, Schuetz JD, et al. Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. J Clin Invest. 1992;90:1871-1878.
-
(1992)
J Clin Invest
, vol.90
, pp. 1871-1878
-
-
Kolars, J.C.1
Schmiedlin-Ren, P.2
Schuetz, J.D.3
-
11
-
-
0025058297
-
Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA
-
Lucey MR, Kolars JC, Merion RM, et al. Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA. Lancet. 1990;335:11-15.
-
(1990)
Lancet
, vol.335
, pp. 11-15
-
-
Lucey, M.R.1
Kolars, J.C.2
Merion, R.M.3
-
12
-
-
0037251643
-
Lopinavir/ritonavir: A review of its use in the management of hiv infection
-
Cvetkovic R, Goa K. Lopinavir/ritonavir: a review of its use in the management of hiv infection. Drugs. 2003;63:769-802.
-
(2003)
Drugs
, vol.63
, pp. 769-802
-
-
Cvetkovic, R.1
Goa, K.2
-
13
-
-
0031959294
-
The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin
-
Backman JT, Kivisto KT, Olkkola KT, et al. The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin. Eur J Clin Pharmacol. 1998;54:53-58.
-
(1998)
Eur J Clin Pharmacol
, vol.54
, pp. 53-58
-
-
Backman, J.T.1
Kivisto, K.T.2
Olkkola, K.T.3
-
14
-
-
0028234586
-
Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily
-
Gorski JC, Hall SD, Jones DR, et al. Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily. Biochem Pharmacol. 1994;47:1643-1653.
-
(1994)
Biochem Pharmacol
, vol.47
, pp. 1643-1653
-
-
Gorski, J.C.1
Hall, S.D.2
Jones, D.R.3
-
15
-
-
0035071598
-
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
-
Kuehl P, Zhang J, Lin Y, et al. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat Genet. 2001;27:383-391.
-
(2001)
Nat Genet
, vol.27
, pp. 383-391
-
-
Kuehl, P.1
Zhang, J.2
Lin, Y.3
-
16
-
-
0036731724
-
Explaining interindividual variability of docetaxel pharmacokinetics and pharmacodynamics in Asians through phenotyping and genotyping strategies
-
Goh BC, Lee SC, Wang LZ, et al. Explaining interindividual variability of docetaxel pharmacokinetics and pharmacodynamics in Asians through phenotyping and genotyping strategies. J Clin Oncol. 2002;20:3683-3690.
-
(2002)
J Clin Oncol
, vol.20
, pp. 3683-3690
-
-
Goh, B.C.1
Lee, S.C.2
Wang, L.Z.3
-
17
-
-
0036892578
-
Pharmacokinetics of midazolam and 1′-hydroxymidazolam in Chinese with different CYP3A5 genotypes
-
Shih PS, Huang JD. Pharmacokinetics of midazolam and 1′ -hydroxymidazolam in Chinese with different CYP3A5 genotypes. Drug Metab Dispos. 2002;30:1491-1496.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1491-1496
-
-
Shih, P.S.1
Huang, J.D.2
-
18
-
-
0007204117
-
Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A
-
Kinirons MT, O'Shea D, Kim RB, et al. Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A. Clin Pharmacol Ther. 1999;66:224-231.
-
(1999)
Clin Pharmacol Ther
, vol.66
, pp. 224-231
-
-
Kinirons, M.T.1
O'Shea, D.2
Kim, R.B.3
-
19
-
-
0027770062
-
Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men
-
Kinirons MT, O'Shea D, Downing TE, et al. Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men. Clin Pharmacol Ther, 1993;54:621-629.
-
(1993)
Clin Pharmacol Ther
, vol.54
, pp. 621-629
-
-
Kinirons, M.T.1
O'Shea, D.2
Downing, T.E.3
-
20
-
-
0026601064
-
Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol
-
Hunt CM, Watkins PB, Saenger P, et al. Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol. Clin Pharmacol Ther. 1992;51:18-23.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 18-23
-
-
Hunt, C.M.1
Watkins, P.B.2
Saenger, P.3
-
21
-
-
0028608020
-
Metabolism of cytochrome P4503A substrates in vivo administered by the same route: Lack of correlation between alfentanil clearance and erythromycin breath test
-
Krivoruk Y, Kinirons MT, Wood AJ, et al. Metabolism of cytochrome P4503A substrates in vivo administered by the same route: lack of correlation between alfentanil clearance and erythromycin breath test. Clin Pharmacol Ther. 1994;56:608-614.
-
(1994)
Clin Pharmacol Ther
, vol.56
, pp. 608-614
-
-
Krivoruk, Y.1
Kinirons, M.T.2
Wood, A.J.3
-
22
-
-
0030060304
-
Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine
-
Stein CM, Kinirons MT, Pincus T, et al. Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine. Clin Pharmacol Ther. 1996;59:47-51.
-
(1996)
Clin Pharmacol Ther
, vol.59
, pp. 47-51
-
-
Stein, C.M.1
Kinirons, M.T.2
Pincus, T.3
-
23
-
-
0035217180
-
The genetic determinants of the CYP3A5 polymorphism
-
Hustert E, Haberl M, Burk O, et al. The genetic determinants of the CYP3A5 polymorphism. Pharmacogenetics. 2001B;11:773-779.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 773-779
-
-
Hustert, E.1
Haberl, M.2
Burk, O.3
-
24
-
-
0036089341
-
Co-regulation ofCYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism
-
Lin YS, Dowling AL, Quigley SD, et al. Co-regulation ofCYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism. Mol Pharmacol. 2002;62:162-172.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 162-172
-
-
Lin, Y.S.1
Dowling, A.L.2
Quigley, S.D.3
-
25
-
-
0035218021
-
In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration
-
Lin YS, Lockwood GF, Graham MA, et al. In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration. Pharmacogenetics. 2001;11:781-791.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 781-791
-
-
Lin, Y.S.1
Lockwood, G.F.2
Graham, M.A.3
-
26
-
-
0023943652
-
Lack of bimodality in nifedipine plasma kinetics in a large population of healthy subjects
-
Schellens JH, Soons PA, Breimer DD. Lack of bimodality in nifedipine plasma kinetics in a large population of healthy subjects. Biochem Pharmacol. 1988;37:2507-2510.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 2507-2510
-
-
Schellens, J.H.1
Soons, P.A.2
Breimer, D.D.3
-
27
-
-
0034736577
-
The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
-
Finta C, Zaphiropoulos PG. The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons. Gene. 2000;260:13-23.
-
(2000)
Gene
, vol.260
, pp. 13-23
-
-
Finta, C.1
Zaphiropoulos, P.G.2
-
28
-
-
17744397194
-
Genomic organization of the human CYP3A locus: Identification of a new, inducible CYP3A gene
-
Gellner K, Eiselt R, Hustert E, et al. Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene. Pharmacogenetics. 2001;11:111-121.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 111-121
-
-
Gellner, K.1
Eiselt, R.2
Hustert, E.3
-
29
-
-
0345638660
-
Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver
-
Molowa DT, Schuetz EG, Wrighton SA, et al. Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver. Proc Natl Acad Sci U S A. 1986;83:5311-5315.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 5311-5315
-
-
Molowa, D.T.1
Schuetz, E.G.2
Wrighton, S.A.3
-
30
-
-
0037155267
-
Intergenic mRNA molecules resulting from trans-splicing
-
Finta C, Zaphiropoulos PG. Intergenic mRNA molecules resulting from trans-splicing. J Biol Chem. 2002;277:5882-5890.
-
(2002)
J Biol Chem
, vol.277
, pp. 5882-5890
-
-
Finta, C.1
Zaphiropoulos, P.G.2
-
31
-
-
0037441832
-
Detection and analysis of spliced chimeric mRNAs in sequence databanks
-
Romani A, Guerra E, Trerotola M, et al. Detection and analysis of spliced chimeric mRNAs in sequence databanks. Nucleic Acids Res. 2003;31:e17.
-
(2003)
Nucleic Acids Res
, vol.31
-
-
Romani, A.1
Guerra, E.2
Trerotola, M.3
-
32
-
-
4644229228
-
Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism
-
Westlind-Johnsson A, Malembo S, Johansson A, et al. Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism. Drug Metab Dispos. 2003;31:1-8.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 1-8
-
-
Westlind-Johnsson, A.1
Malembo, S.2
Johansson, A.3
-
33
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
Shimada T, Yamazaki H, Mimura M, et al. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther. 1994;270:414-423.
-
(1994)
J Pharmacol Exp Ther
, vol.270
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
-
34
-
-
0036786382
-
Interindividual variability and tissue-specificity in the expression of cytochrome P450 3A mRNA
-
Koch I, Weil R, Wolbold R, et al. interindividual variability and tissue-specificity in the expression of cytochrome P450 3A mRNA. Drug Metab Dispos. 2002;30:1108-1114.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1108-1114
-
-
Koch, I.1
Weil, R.2
Wolbold, R.3
-
35
-
-
0033561681
-
No ethnic difference between Caucasian and Japanese hepatic samples in the expression frequency of CYP3A5 and CYP3A7 proteins
-
Tateishi T, Watanabe M, Moriya H, et al. No ethnic difference between Caucasian and Japanese hepatic samples in the expression frequency of CYP3A5 and CYP3A7 proteins. Biochem Pharmacol. 1999;57:935-939.
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 935-939
-
-
Tateishi, T.1
Watanabe, M.2
Moriya, H.3
-
36
-
-
0037025341
-
Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine
-
Burk O, Tegude H, Koch I, et al. Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine. J Biol Chem. 2002;277:24280-24288.
-
(2002)
J Biol Chem
, vol.277
, pp. 24280-24288
-
-
Burk, O.1
Tegude, H.2
Koch, I.3
-
37
-
-
0034811058
-
Cloning and tissue distribution of a novel human cytochrome p450 of the CYP3A subfamily, CYP3A43
-
Westlind A, Malmebo S, Johansson I, et al. Cloning and tissue distribution of a novel human cytochrome p450 of the CYP3A subfamily, CYP3A43. Biochem Biophys Res Commun. 2001;281:1349-1355.
-
(2001)
Biochem Biophys Res Commun
, vol.281
, pp. 1349-1355
-
-
Westlind, A.1
Malmebo, S.2
Johansson, I.3
-
38
-
-
0035135258
-
cDNA cloning and initial characterization of CYP3A43, a novel human cytochrome P450
-
Domanski TL, Finta C, Halpert JR, et al. cDNA cloning and initial characterization of CYP3A43, a novel human cytochrome P450. Mol Pharmacol. 2001B;59:386-392.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 386-392
-
-
Domanski, T.L.1
Finta, C.2
Halpert, J.R.3
-
39
-
-
0025161416
-
Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3)
-
Wrighton SA, Brian WR, Sari MA, et al. Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3). Mol Pharmacol. 1990;38:207-213.
-
(1990)
Mol Pharmacol
, vol.38
, pp. 207-213
-
-
Wrighton, S.A.1
Brian, W.R.2
Sari, M.A.3
-
40
-
-
0037349259
-
The distribution and gender difference of CYP3A activity in Chinese subjects
-
Zhu B, Liu ZQ, Chen GL, et al. The distribution and gender difference of CYP3A activity in Chinese subjects. Br J Clin Pharmacol. 2003;55:264-269.
-
(2003)
Br J Clin Pharmacol
, vol.55
, pp. 264-269
-
-
Zhu, B.1
Liu, Z.Q.2
Chen, G.L.3
-
41
-
-
0036377091
-
Modeling of human hepatic CYP3A4 enzyme kinetics, protein, and mRNA indicates deviation from log-normal distribution in CYP3A4 gene expression
-
Sy SK, Ciaccia A, Li W, et al. Modeling of human hepatic CYP3A4 enzyme kinetics, protein, and mRNA indicates deviation from log-normal distribution in CYP3A4 gene expression. Eur J Clin Pharmacol. 2002;58:357-365.
-
(2002)
Eur J Clin Pharmacol
, vol.58
, pp. 357-365
-
-
Sy, S.K.1
Ciaccia, A.2
Li, W.3
-
42
-
-
0033610010
-
Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver
-
Sumida A, Kinoshita K, Fukuda T, et al. Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver. Biochem Biophys Res Commun. 1999;262:499-503.
-
(1999)
Biochem Biophys Res Commun
, vol.262
, pp. 499-503
-
-
Sumida, A.1
Kinoshita, K.2
Fukuda, T.3
-
43
-
-
0023588109
-
Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man
-
Watkins PB, Wrighton SA, Schuetz EG, et al. Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man. J Clin Invest. 1987;80:1029-1036.
-
(1987)
J Clin Invest
, vol.80
, pp. 1029-1036
-
-
Watkins, P.B.1
Wrighton, S.A.2
Schuetz, E.G.3
-
44
-
-
0028801964
-
Characterisation of CYP3A gene subfamily expression in human gastrointestinal tissues
-
McKinnon RA, Burgess WM, Hall PM, et al. Characterisation of CYP3A gene subfamily expression in human gastrointestinal tissues. Gut. 1995;36:259-267.
-
(1995)
Gut
, vol.36
, pp. 259-267
-
-
McKinnon, R.A.1
Burgess, W.M.2
Hall, P.M.3
-
46
-
-
0032976876
-
Immunohistochemical study of cytochrome P450 2C and 3A in human non-neoplastic and neoplastic tissues
-
Yokose T, Doy M, Taniguchi T, et al. Immunohistochemical study of cytochrome P450 2C and 3A in human non-neoplastic and neoplastic tissues. Virchows Arch. 1999;434:401-411.
-
(1999)
Virchows Arch
, vol.434
, pp. 401-411
-
-
Yokose, T.1
Doy, M.2
Taniguchi, T.3
-
47
-
-
0023898817
-
The immunocytochemical localisation and distribution of cytochrome P-450 in normal human hepatic and extrahepatic tissues with a monoclonal antibody to human cytochrome P-450
-
Murray GI, Barnes TS, Sewell HF, et al. The immunocytochemical localisation and distribution of cytochrome P-450 in normal human hepatic and extrahepatic tissues with a monoclonal antibody to human cytochrome P-450. Br J Clin Pharmacol. 1988;25:465-475.
-
(1988)
Br J Clin Pharmacol
, vol.25
, pp. 465-475
-
-
Murray, G.I.1
Barnes, T.S.2
Sewell, H.F.3
-
48
-
-
0033042397
-
Cytochrome P450 CYP3A in human renal cell cancer
-
Murray GI, McFadyen MC, Mitchell RT, et al. Cytochrome P450 CYP3A in human renal cell cancer. Br J Cancer. 1999;79:1836-1842.
-
(1999)
Br J Cancer
, vol.79
, pp. 1836-1842
-
-
Murray, G.I.1
McFadyen, M.C.2
Mitchell, R.T.3
-
49
-
-
0030006845
-
Bimodal distribution of renal cytochrome P450 3A activity in humans
-
Haehner BD, Gorski JC, Vandenbranden M, et al. Bimodal distribution of renal cytochrome P450 3A activity in humans. Mol Pharmacol. 1996;50:52-59.
-
(1996)
Mol Pharmacol
, vol.50
, pp. 52-59
-
-
Haehner, B.D.1
Gorski, J.C.2
Vandenbranden, M.3
-
50
-
-
0033086126
-
Mechanisms and significance of inhibitory drug interactions involving cytochrome P450 enzymes
-
Murray M. Mechanisms and significance of inhibitory drug interactions involving cytochrome P450 enzymes (review). Int J Mol Med. 1999;3:227-238.
-
(1999)
Int J Mol Med
, vol.3
, pp. 227-238
-
-
Murray, M.1
-
51
-
-
0032498303
-
An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway
-
Kliewer SA, Moore JT, Wade L, et al. An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway. Cell. 1998;92:73-82.
-
(1998)
Cell
, vol.92
, pp. 73-82
-
-
Kliewer, S.A.1
Moore, J.T.2
Wade, L.3
-
52
-
-
0032169485
-
The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
-
Lehmann JM, McKee DD, Watson MA, et al. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J Clin Invest. 1998;102:1016-1023.
-
(1998)
J Clin Invest
, vol.102
, pp. 1016-1023
-
-
Lehmann, J.M.1
McKee, D.D.2
Watson, M.A.3
-
53
-
-
13144260727
-
Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction
-
Bertilsson G, Heidrich J, Svensson K, et al. Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction. Proc Natl Acad Sci USA. 1998;95:12208-12213.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 12208-12213
-
-
Bertilsson, G.1
Heidrich, J.2
Svensson, K.3
-
54
-
-
0032532134
-
SXR, a novel steroid and xenobiotic-sensing nuclear receptor
-
Blumberg B, Sabbagh W Jr, Juguilon H, et al. SXR, a novel steroid and xenobiotic-sensing nuclear receptor. Genes Dev. 1998;12:3195-3205.
-
(1998)
Genes Dev
, vol.12
, pp. 3195-3205
-
-
Blumberg, B.1
Sabbagh Jr., W.2
Juguilon, H.3
-
55
-
-
17744375160
-
The pregnane X receptor: A promiscuous xenobiotic receptor that has diverged during evolution
-
Jones SA, Moore LB, Shenk JL, et al. The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution. Mol Endocrinol. 2000;14:27-39.
-
(2000)
Mol Endocrinol
, vol.14
, pp. 27-39
-
-
Jones, S.A.1
Moore, L.B.2
Shenk, J.L.3
-
56
-
-
0034721159
-
Humanized xenobiotic response in mice expressing nuclear receptor SXR
-
Xie W, Barwick JL, Downes M, et al. Humanized xenobiotic response in mice expressing nuclear receptor SXR. Nature. 2000;406:435-439.
-
(2000)
Nature
, vol.406
, pp. 435-439
-
-
Xie, W.1
Barwick, J.L.2
Downes, M.3
-
57
-
-
0033638960
-
Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR
-
Xie W, Barwick JL, Simon CM, et al. Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR. Genes Dev. 2000;14:3014-3023.
-
(2000)
Genes Dev
, vol.14
, pp. 3014-3023
-
-
Xie, W.1
Barwick, J.L.2
Simon, C.M.3
-
58
-
-
0035918186
-
Orphan receptor promiscuity in the induction of cytochromes p450 by xenobiotics
-
Smirlis D, Muangmoonchai R, Edwards M, et al. Orphan receptor promiscuity in the induction of cytochromes p450 by xenobiotics. J Biol Chem. 2001;276:12822-12826.
-
(2001)
J Biol Chem
, vol.276
, pp. 12822-12826
-
-
Smirlis, D.1
Muangmoonchai, R.2
Edwards, M.3
-
59
-
-
0036070955
-
Transcriptional regulation of the human CYP3A4 gene by the constitutive androstane receptor
-
Goodwin B, Hodgson E, D'Costa DJ, et al. Transcriptional regulation of the human CYP3A4 gene by the constitutive androstane receptor. Mol Pharmacol. 2002;62:359-365.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 359-365
-
-
Goodwin, B.1
Hodgson, E.2
D'Costa, D.J.3
-
60
-
-
0031682988
-
The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene
-
Honkakoski P, Zelko I, Sueyoshi T, et al. The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene. Mol Cell Biol. 1998;18:5652-5658.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5652-5658
-
-
Honkakoski, P.1
Zelko, I.2
Sueyoshi, T.3
-
61
-
-
0030945754
-
Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxy-vitamin D3
-
Schmiedlin-Ren P, Thummel KE, Fisher JM, et al. Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxy-vitamin D3. Mol Pharmacol. 1997;51:741-754.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 741-754
-
-
Schmiedlin-Ren, P.1
Thummel, K.E.2
Fisher, J.M.3
-
62
-
-
0034776256
-
Induction of cyp3a4 by 1alpha,25-dihydroxyvitamin d(3) is human cell line-specific and is unlikely to involve pregnane x receptor
-
Schmiedlin-Ren P, Thummel KE, Fisher JM, et al. Induction of cyp3a4 by 1alpha,25-dihydroxyvitamin d(3) is human cell line-specific and is unlikely to involve pregnane x receptor. Drug Metab Dispos. 2001;29:1446-1453.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 1446-1453
-
-
Schmiedlin-Ren, P.1
Thummel, K.E.2
Fisher, J.M.3
-
63
-
-
0035206829
-
Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3
-
Thummel KE, Brimer C, Yasuda K, et al. Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3. Mol Pharmacol. 2001;60:1399-1406.
-
(2001)
Mol Pharmacol
, vol.60
, pp. 1399-1406
-
-
Thummel, K.E.1
Brimer, C.2
Yasuda, K.3
-
64
-
-
0029992789
-
Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes
-
Barwick JL, Quattrochi LC, Mills AS, et al. Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes. Mol Pharmacol. 1996;50:10-16.
-
(1996)
Mol Pharmacol
, vol.50
, pp. 10-16
-
-
Barwick, J.L.1
Quattrochi, L.C.2
Mills, A.S.3
-
65
-
-
0032702726
-
The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module
-
Goodwin B, Hodgson E, Liddle C. The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module. Mol Pharmacol. 1999;56:1329-1339.
-
(1999)
Mol Pharmacol
, vol.56
, pp. 1329-1339
-
-
Goodwin, B.1
Hodgson, E.2
Liddle, C.3
-
66
-
-
0037327003
-
The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4
-
Tirona RG, Lee W, Leake BF, et al. The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4. Nature Med. 2003;9:220-224.
-
(2003)
Nature Med
, vol.9
, pp. 220-224
-
-
Tirona, R.G.1
Lee, W.2
Leake, B.F.3
-
67
-
-
0034811083
-
Functionally conserved xenobiotic responsive enhancer in cytochrome P450 3A7
-
Bertilsson G, Berkenstam A, Blomquist P. Functionally conserved xenobiotic responsive enhancer in cytochrome P450 3A7. Biochem Biophys Res Commun. 2001;280:139-144.
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 139-144
-
-
Bertilsson, G.1
Berkenstam, A.2
Blomquist, P.3
-
68
-
-
0028585920
-
Sequence of the 5′-flanking region of CYP3A5: Comparative analysis with CYP3A4 and CYP3A7
-
Jounaidi Y, Guzelian PS, Maurel P, et al. Sequence of the 5′-flanking region of CYP3A5: comparative analysis with CYP3A4 and CYP3A7. Biochem Biophys Res Commun. 1994;205:1741-1747.
-
(1994)
Biochem Biophys Res Commun
, vol.205
, pp. 1741-1747
-
-
Jounaidi, Y.1
Guzelian, P.S.2
Maurel, P.3
-
69
-
-
0030059885
-
Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells
-
Schuetz JD, Schuetz EG, Thottassery JV, et al. Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells. Mol Pharmacol. 1996;49:63-72.
-
(1996)
Mol Pharmacol
, vol.49
, pp. 63-72
-
-
Schuetz, J.D.1
Schuetz, E.G.2
Thottassery, J.V.3
-
70
-
-
0037308012
-
Regulation of CYP3A5 by glucocorticoids and cigarette smoke in human lung-derived cells
-
Hukkanen J, Vaisanen T, Lassila A, et al. Regulation of CYP3A5 by glucocorticoids and cigarette smoke in human lung-derived cells. J Pharmacol Exp Ther. 2003;304:745-752.
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 745-752
-
-
Hukkanen, J.1
Vaisanen, T.2
Lassila, A.3
-
71
-
-
0033931266
-
Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: Synergistic increase of CYP3A4 induction by pregnane X receptor activators
-
Pascussi JM, Drocourt L, Fabre JM, et al. Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators. Mol Pharmacol. 2000A;58:361-372.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 361-372
-
-
Pascussi, J.M.1
Drocourt, L.2
Fabre, J.M.3
-
72
-
-
0033664347
-
Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: Consequences on cytochrome P450 gene regulation
-
Pascussi JM, Gerbal-Chaloin S, Fabre JM, et al. Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: consequences on cytochrome P450 gene regulation. Mol Pharmacol. 2000B;58:1441-1450.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 1441-1450
-
-
Pascussi, J.M.1
Gerbal-Chaloin, S.2
Fabre, J.M.3
-
73
-
-
0032547341
-
Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4
-
Rebbeck TR, Jaffe JM, Walker AH, et al. Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4 [published erratum appears in J Natl Cancer Inst 1999;91:1082]. J Natl Cancer Inst. 1998;90:1225-1229.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1225-1229
-
-
Rebbeck, T.R.1
Jaffe, J.M.2
Walker, A.H.3
-
74
-
-
0033575065
-
-
published erratum appears in
-
Rebbeck TR, Jaffe JM, Walker AH, et al. Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4 [published erratum appears in J Natl Cancer Inst 1999;91:1082]. J Natl Cancer Inst. 1998;90:1225-1229.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1082
-
-
-
75
-
-
0037139169
-
Mutation analysis of the human CYP3A4 gene 5′ regulatory region: Population screening using non-radioactive SSCP
-
Hamzeiy H, Vahdati-Mashhadian N, Edwards HJ, et al. Mutation analysis of the human CYP3A4 gene 5′ regulatory region: population screening using non-radioactive SSCP. Mutat Res. 2002;500:103-110.
-
(2002)
Mutat Res
, vol.500
, pp. 103-110
-
-
Hamzeiy, H.1
Vahdati-Mashhadian, N.2
Edwards, H.J.3
-
76
-
-
0033632228
-
CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: Evidence for an allelic variant with altered catalytic activity
-
Sata F, Sapone A, Elizondo G, et al. CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: evidence for an allelic variant with altered catalytic activity. Clin Pharmacol Ther. 2000;67:48-56.
-
(2000)
Clin Pharmacol Ther
, vol.67
, pp. 48-56
-
-
Sata, F.1
Sapone, A.2
Elizondo, G.3
-
77
-
-
0034959461
-
Identification and functional characterization of eight CYP3A4 protein variants
-
Eiselt R, Domanski TL, Zibat A, et al. Identification and functional characterization of eight CYP3A4 protein variants. Pharmacogenetics. 2001;11:447-458.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 447-458
-
-
Eiselt, R.1
Domanski, T.L.2
Zibat, A.3
-
78
-
-
0036219998
-
Common allelic variants of cytochrome P4503A4 and their prevalence in different populations
-
Lamba JK, Lin YS, Thummel K, et al. Common allelic variants of cytochrome P4503A4 and their prevalence in different populations. Pharmacogenetics. 2002;12:121-132.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 121-132
-
-
Lamba, J.K.1
Lin, Y.S.2
Thummel, K.3
-
79
-
-
0035197548
-
Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos
-
Dai D, Tang J, Rose R, et al. Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos. J Pharmacol Exp Ther. 2001;299:825-831.
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 825-831
-
-
Dai, D.1
Tang, J.2
Rose, R.3
-
81
-
-
0036582834
-
CYP3A4 promoter variant is associated with prostate cancer risk in men with benign prostate hyperplasia
-
Tayeb MT, Clark C, Sharp L, et al. CYP3A4 promoter variant is associated with prostate cancer risk in men with benign prostate hyperplasia. Oncol Rep. 2002;9:653-655.
-
(2002)
Oncol Rep
, vol.9
, pp. 653-655
-
-
Tayeb, M.T.1
Clark, C.2
Sharp, L.3
-
82
-
-
0032756477
-
Association between a CYP3A4 genetic variant and clinical presentation in African-American prostate cancer patients
-
Paris PL, Kupelian PA, Hall JM, et al. Association between a CYP3A4 genetic variant and clinical presentation in African-American prostate cancer patients. Cancer Epidemiol Biomarkers Prev. 1999;8:901-905.
-
(1999)
Cancer Epidemiol Biomarkers Prev
, vol.8
, pp. 901-905
-
-
Paris, P.L.1
Kupelian, P.A.2
Hall, J.M.3
-
83
-
-
13144282667
-
Association of CYP3A4 genotype with treatment-related leukemia
-
Felix CA, Walker AH, Lange BJ, et al. Association of CYP3A4 genotype with treatment-related leukemia. Proc Natl Acad Sci U S A. 1998;95:13176-13181.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13176-13181
-
-
Felix, C.A.1
Walker, A.H.2
Lange, B.J.3
-
84
-
-
12244252803
-
Genetic polymorphisms in CYP3A5, CYP3A4 and NQO1 in children who developed therapy-related myeloid malignancies
-
Blanco JG, Edick MJ, Hancock ML, et al. Genetic polymorphisms in CYP3A5, CYP3A4 and NQO1 in children who developed therapy-related myeloid malignancies. Pharmacogenetics. 2002;12:605-611.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 605-611
-
-
Blanco, J.G.1
Edick, M.J.2
Hancock, M.L.3
-
85
-
-
0036221255
-
CYP3A4 variant alleles in white individuals with low CYP3A4 enzyme activity
-
Garcia-Martin E, Martinez C, Pizarro RM, et al. CYP3A4 variant alleles in white individuals with low CYP3A4 enzyme activity. Clin Pharmacol Ther. 2002;71:196-204.
-
(2002)
Clin Pharmacol Ther
, vol.71
, pp. 196-204
-
-
Garcia-Martin, E.1
Martinez, C.2
Pizarro, R.M.3
-
86
-
-
0033568497
-
Re: Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4
-
Ando Y, Tateishi T, Sekido Y, et al. Re: Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4. J Natl Cancer Inst. 1999;91:1587-1590.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1587-1590
-
-
Ando, Y.1
Tateishi, T.2
Sekido, Y.3
-
87
-
-
0345643389
-
Interindividual differences in hepatic expression of CYP3A4: Relationship to genetic polymorphism in the 5′-upstream regulatory region
-
Westlind A, Lofberg L, Tindberg N, et al. Interindividual differences in hepatic expression of CYP3A4: relationship to genetic polymorphism in the 5′-upstream regulatory region. Biochem Biophys Res Commun. 1999;259:201-205.
-
(1999)
Biochem Biophys Res Commun
, vol.259
, pp. 201-205
-
-
Westlind, A.1
Lofberg, L.2
Tindberg, N.3
-
88
-
-
0000576297
-
RESPONSE: Re: Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4
-
Amirimani B, Walker AH, Weber BL, et al. RESPONSE: re: modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4. J Natl Cancer Inst. 1999;91:1588-1590.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1588-1590
-
-
Amirimani, B.1
Walker, A.H.2
Weber, B.L.3
-
89
-
-
0036020978
-
The CYP3A4*1B polymorphism has no functional significance and is not associated with risk of breast or ovarian cancer
-
Spurdle AB, Goodwin B, Hodgson E, et al. The CYP3A4*1B polymorphism has no functional significance and is not associated with risk of breast or ovarian cancer. Pharmacogenetics. 2002;12:355-366.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 355-366
-
-
Spurdle, A.B.1
Goodwin, B.2
Hodgson, E.3
-
90
-
-
0037123351
-
Re: Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4
-
Wojnowski L, Hustert E, Klein K, et al. Re: Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4. J Natl Cancer Inst. 2002;94:630-631.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 630-631
-
-
Wojnowski, L.1
Hustert, E.2
Klein, K.3
-
91
-
-
0034785945
-
The human pregnane X receptor: Genomic structure and identification and functional characterization of natural allelic variants
-
Zhang J, Kuehl P, Green ED, et al. The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants. Pharmacogenetics. 2001;11:555-572.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 555-572
-
-
Zhang, J.1
Kuehl, P.2
Green, E.D.3
-
92
-
-
0034777488
-
Natural protein variants of pregnane x receptor with altered transactivation activity toward cyp3a4
-
Hustert E, Zibat A, Presecan-Siedel E, et al. Natural protein variants of pregnane x receptor with altered transactivation activity toward cyp3a4. Drug Metab Dispos. 2001A;29:1454-1459.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 1454-1459
-
-
Hustert, E.1
Zibat, A.2
Presecan-Siedel, E.3
-
93
-
-
0035659943
-
Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor
-
Pascussi JM, Drocourt L, Gerbal-Chaloin S, et al. Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor. Eur J Biochem. 2001;268:6346-6358.
-
(2001)
Eur J Biochem
, vol.268
, pp. 6346-6358
-
-
Pascussi, J.M.1
Drocourt, L.2
Gerbal-Chaloin, S.3
-
94
-
-
0038128342
-
Constitutive Androstane Receptor and Pregnane X Receptor Gene Expression in Human Liver: Interindividual Variability and Correlation with CYP2B6 mRNA Levels
-
Chang TK, Bandiera SM, Chen J. Constitutive Androstane Receptor and Pregnane X Receptor Gene Expression in Human Liver: Interindividual Variability and Correlation with CYP2B6 mRNA Levels. Drug Metab Dispos. 2003;31:7-10.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 7-10
-
-
Chang, T.K.1
Bandiera, S.M.2
Chen, J.3
-
95
-
-
0034090310
-
Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha
-
Li J, Ning G, Duncan SA. Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. Genes Dev. 2000;14:464-474.
-
(2000)
Genes Dev
, vol.14
, pp. 464-474
-
-
Li, J.1
Ning, G.2
Duncan, S.A.3
-
96
-
-
0035141324
-
Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis
-
Hayhurst GP, Lee YH, Lambert G, et al. Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis. Mol Cell Biol. 2001;21:1393-1403.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1393-1403
-
-
Hayhurst, G.P.1
Lee, Y.H.2
Lambert, G.3
-
97
-
-
0033932053
-
Two linked mutations in transcriptional regulatory elements of the CYP3A5 gene constitute the major genetic determinant of polymorphic activity in humans
-
Paulussen A, Lavrijsen K, Bohets H, et al. Two linked mutations in transcriptional regulatory elements of the CYP3A5 gene constitute the major genetic determinant of polymorphic activity in humans. Pharmacogenetics. 2000;10:415-424.
-
(2000)
Pharmacogenetics
, vol.10
, pp. 415-424
-
-
Paulussen, A.1
Lavrijsen, K.2
Bohets, H.3
-
98
-
-
0036016319
-
Novel detection assay by PCR-RFLP and frequency of the CYP3A5 SNPs, CYP3A5*3 and *6, in a Japanese population
-
Fukuen S, Fukuda T, Maune H, et al. Novel detection assay by PCR-RFLP and frequency of the CYP3A5 SNPs, CYP3A5*3 and *6, in a Japanese population. Pharmacogenetics. 2002;12:331-334.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 331-334
-
-
Fukuen, S.1
Fukuda, T.2
Maune, H.3
-
100
-
-
0034874776
-
Genetic polymorphism of cytochrome P450 3A5 in Chinese
-
Chou FC, Tzeng SJ, Huang JD. Genetic polymorphism of cytochrome P450 3A5 in Chinese. Drug Metab Dispos. 2001;29:1205-1209.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 1205-1209
-
-
Chou, F.C.1
Tzeng, S.J.2
Huang, J.D.3
-
101
-
-
0041881985
-
Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups
-
Lee SJ, Usmani KA, Chanas B, et al. Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups. Pharmacogenetics. 2003;13:461-472.
-
(2003)
Pharmacogenetics
, vol.13
, pp. 461-472
-
-
Lee, S.J.1
Usmani, K.A.2
Chanas, B.3
-
102
-
-
17444443721
-
Metabolism of irinotecan (CPT-11) by CYP3A4 and CYP3A5 in humans
-
Santos A, Zanetta S, Cresteil T, et al. Metabolism of irinotecan (CPT-11) by CYP3A4 and CYP3A5 in humans. Clin Cancer Res. 2000;6:2012-2020.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2012-2020
-
-
Santos, A.1
Zanetta, S.2
Cresteil, T.3
-
103
-
-
0028912205
-
Expression of cytochrome P450 3A5 in Escherichia coli: Effects of 5′ modification, purification, spectral characterization, reconstitution conditions, and catalytic activities
-
Gillam EM, Guo Z, Ueng YF, et al. Expression of cytochrome P450 3A5 in Escherichia coli: effects of 5′ modification, purification, spectral characterization, reconstitution conditions, and catalytic activities [published erratum appears in Arch Biochem Biophys. 1995;318:498] Arch Biochem Biophys. 1995;317:374-384.
-
(1995)
Arch Biochem Biophys
, vol.317
, pp. 374-384
-
-
Gillam, E.M.1
Guo, Z.2
Ueng, Y.F.3
-
104
-
-
0028946799
-
-
published erratum appears
-
Gillam EM, Guo Z, Ueng YF, et al. Expression of cytochrome P450 3A5 in Escherichia coli: effects of 5′ modification, purification, spectral characterization, reconstitution conditions, and catalytic activities [published erratum appears in Arch Biochem Biophys. 1995;318:498] Arch Biochem Biophys. 1995;317:374-384.
-
(1995)
Arch Biochem Biophys
, vol.318
, pp. 498
-
-
-
105
-
-
0032497361
-
Structure-function relationships of human liver cytochromes P450 3A: Aflatoxin B1 metabolism as a probe
-
Wang H, Dick R, Yin H, et al. Structure-function relationships of human liver cytochromes P450 3A: aflatoxin B1 metabolism as a probe. Biochemistry (Mosc). 1998;37:12536-12545.
-
(1998)
Biochemistry (Mosc)
, vol.37
, pp. 12536-12545
-
-
Wang, H.1
Dick, R.2
Yin, H.3
-
106
-
-
0024412071
-
Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine
-
Aoyama T, Yamano S, Waxman DJ, et al. Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine. J Biol Chem. 1989;264:10388-10395.
-
(1989)
J Biol Chem
, vol.264
, pp. 10388-10395
-
-
Aoyama, T.1
Yamano, S.2
Waxman, D.J.3
-
107
-
-
0037693831
-
Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms
-
Zheng H, Webber S, Zeevi A, et al. Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms. Am J Transplant. 2003;3:477-483.
-
(2003)
Am J Transplant
, vol.3
, pp. 477-483
-
-
Zheng, H.1
Webber, S.2
Zeevi, A.3
-
108
-
-
0037115210
-
Tacrolimus pharmacogenetics: Polymorphisms associated with expression of cytochrome p4503A5 and P-glycoprotein correlate with dose requirement
-
Macphee IA, Fredericks S, Tai T, et al. Tacrolimus pharmacogenetics: polymorphisms associated with expression of cytochrome p4503A5 and P-glycoprotein correlate with dose requirement. Transplantation. 2002;74:1486-1489.
-
(2002)
Transplantation
, vol.74
, pp. 1486-1489
-
-
Macphee, I.A.1
Fredericks, S.2
Tai, T.3
-
109
-
-
0036320872
-
Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7
-
Williams JA, Ring BJ, Cantrell VE, et al. Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7. Drug Metab Dispos. 2002;30:883-891.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 883-891
-
-
Williams, J.A.1
Ring, B.J.2
Cantrell, V.E.3
-
110
-
-
0033674630
-
Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites
-
Marill J, Cresteil T, Lanotte M, et al. Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites. Mol Pharmacol. 2000;58:1341-1348.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 1341-1348
-
-
Marill, J.1
Cresteil, T.2
Lanotte, M.3
-
111
-
-
0031779718
-
Steroid hydroxylation by human fetal CYP3A7 and human NADPH-cytochrome P450 reductase coexpressed in insect cells using baculovirus
-
Ohmori S, Fujiki N, Nakasa H, et al. Steroid hydroxylation by human fetal CYP3A7 and human NADPH-cytochrome P450 reductase coexpressed in insect cells using baculovirus. Res Commun Mol Pathol Pharmacol. 1998;100:15-28.
-
(1998)
Res Commun Mol Pathol Pharmacol
, vol.100
, pp. 15-28
-
-
Ohmori, S.1
Fujiki, N.2
Nakasa, H.3
-
112
-
-
0032496311
-
Differential catalytic properties in metabolism of endogenous and exogenous substrates among CYP3A enzymes expressed in COS-7 cells
-
Ohmori S, Nakasa H, Asanome K, et al. Differential catalytic properties in metabolism of endogenous and exogenous substrates among CYP3A enzymes expressed in COS-7 cells. Biochim Biophys Acta. 1998;1380:297-304.
-
(1998)
Biochim Biophys Acta
, vol.1380
, pp. 297-304
-
-
Ohmori, S.1
Nakasa, H.2
Asanome, K.3
|