-
1
-
-
0024541342
-
Evidence for cytochrome P450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver
-
Shimada, T., and F. P. Guengerich. Evidence for cytochrome P450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver. Proc. Natl. Acad. Sci. USA 86:462-465 (1989).
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 462-465
-
-
Shimada, T.1
Guengerich, F.P.2
-
2
-
-
0023588109
-
Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man
-
Watkins, P. B., S. A. Wrighton, E. G. Schuetz, D. T. Molowa, and P. S. Guzelian. Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man. J. Clin. Invest. 80:1029-1036 (1987).
-
(1987)
J. Clin. Invest.
, vol.80
, pp. 1029-1036
-
-
Watkins, P.B.1
Wrighton, S.A.2
Schuetz, E.G.3
Molowa, D.T.4
Guzelian, P.S.5
-
3
-
-
0026464616
-
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
-
Kolars, J. C., P. Schmiedlin-Ren, J. D. Schuetz, C. Fang, and P. B. Watkins. Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. J. Clin. Invest. 90:1871-1878 (1992).
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 1871-1878
-
-
Kolars, J.C.1
Schmiedlin-Ren, P.2
Schuetz, J.D.3
Fang, C.4
Watkins, P.B.5
-
4
-
-
0027954308
-
Catalytic selectivity of human cytochrome P450 enzymes: Relevance to drug metabolism and toxicity
-
Guengerich, F. P. Catalytic selectivity of human cytochrome P450 enzymes: relevance to drug metabolism and toxicity. Toxicol. Lett. 70:133-138 (1994).
-
(1994)
Toxicol. Lett.
, vol.70
, pp. 133-138
-
-
Guengerich, F.P.1
-
5
-
-
0025719746
-
First-pass metabolism of cyclosporin by the gut
-
Kolars, J. C., W. M. Awni, R. M. Merion, and P. B. Watkins. First-pass metabolism of cyclosporin by the gut. Lancet 338:1488-1490 (1991).
-
(1991)
Lancet
, vol.338
, pp. 1488-1490
-
-
Kolars, J.C.1
Awni, W.M.2
Merion, R.M.3
Watkins, P.B.4
-
6
-
-
0026457407
-
Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction
-
Hebert, M. F., J. P. Roberts, T. Prueksaritanont, and L. Z. Benet. Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction. Clin. Pharmacol. Ther. 52:453-457 (1992).
-
(1992)
Clin. Pharmacol. Ther.
, vol.52
, pp. 453-457
-
-
Hebert, M.F.1
Roberts, J.P.2
Prueksaritanont, T.3
Benet, L.Z.4
-
7
-
-
0029123393
-
The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine
-
Gomez, D. Y., V. J. Wacher, S. J. Tomlanovich, M. F. Hebert, and L. Z. Benet. The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine. Clin. Pharmacol. Ther. 58:15-19 (1995).
-
(1995)
Clin. Pharmacol. Ther.
, vol.58
, pp. 15-19
-
-
Gomez, D.Y.1
Wacher, V.J.2
Tomlanovich, S.J.3
Hebert, M.F.4
Benet, L.Z.5
-
8
-
-
0030015297
-
Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism
-
Thummel, K. E., D. O'Shea, M. F. Paine, D. D. Shen, K. L. Kunze, J. D. Perkins, and G. R. Wilkinson. Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism. Clin. Pharmacol. Ther. 59:491-502 (1996).
-
(1996)
Clin. Pharmacol. Ther.
, vol.59
, pp. 491-502
-
-
Thummel, K.E.1
O'Shea, D.2
Paine, M.F.3
Shen, D.D.4
Kunze, K.L.5
Perkins, J.D.6
Wilkinson, G.R.7
-
9
-
-
0029738490
-
First-pass metabolism of midazolam by the human intestine
-
Paine, M. F., D. D. Shen, K. L. Kunze, J. D. Perkins, C. L. Marsh, J. P. McVicar, D. M. Barr, B. S. Gillies, and K. E. Thummel. First-pass metabolism of midazolam by the human intestine. Clin. Pharmacol. Ther. 60: 14-24 (1996).
-
(1996)
Clin. Pharmacol. Ther.
, vol.60
, pp. 14-24
-
-
Paine, M.F.1
Shen, D.D.2
Kunze, K.L.3
Perkins, J.D.4
Marsh, C.L.5
McVicar, J.P.6
Barr, D.M.7
Gillies, B.S.8
Thummel, K.E.9
-
10
-
-
0021067619
-
Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture
-
Pinto, M., S. Rubine-Leon, M.-D. Appay, M. Kedinger, N. Triadou, E. Dussaulx, B. LaCroix, P. Simon-Assmann, K. Haffen, J. Fogh, and A. Zweibaum. Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture. Biol. Cell 47:323-330 (1983).
-
(1983)
Biol. Cell
, vol.47
, pp. 323-330
-
-
Pinto, M.1
Rubine-Leon, S.2
Appay, M.-D.3
Kedinger, M.4
Triadou, N.5
Dussaulx, E.6
LaCroix, B.7
Simon-Assmann, P.8
Haffen, K.9
Fogh, J.10
Zweibaum, A.11
-
11
-
-
0024593744
-
Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability
-
Hidalgo, I. J., T. J. Raub, and R. T. Borchardt. Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology 96:736-749 (1989).
-
(1989)
Gastroenterology
, vol.96
, pp. 736-749
-
-
Hidalgo, I.J.1
Raub, T.J.2
Borchardt, R.T.3
-
12
-
-
0025189818
-
Transport and permeability properties of human Caco-2 cells: An in vitro model of the intestinal epithelial cell barrier
-
Wilson, G., I. F. Hassan, C. J. Dix, I. Williamson, R. Shah, M. Mackay, and P. Artursson. Transport and permeability properties of human Caco-2 cells: an in vitro model of the intestinal epithelial cell barrier. J. Control. Rel. 11:25-40 (1990).
-
(1990)
J. Control. Rel.
, vol.11
, pp. 25-40
-
-
Wilson, G.1
Hassan, I.F.2
Dix, C.J.3
Williamson, I.4
Shah, R.5
Mackay, M.6
Artursson, P.7
-
13
-
-
0027146389
-
Transport of celiprolol across human intestinal epithelial (Caco-2) cells: Mediation of secretion by multiple transporters including P-glycoprotein
-
Karlsson, J., S.-M. Kuo, J. Ziemniak, and P. Artursson. Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein. Br. J. Pharmacol. 110:1009-1016 (1993).
-
(1993)
Br. J. Pharmacol.
, vol.110
, pp. 1009-1016
-
-
Karlsson, J.1
Kuo, S.-M.2
Ziemniak, J.3
Artursson, P.4
-
14
-
-
0027181852
-
Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells
-
Hunter, J., M. A. Jepson, T. Tsuruo, N. L. Simmons, and B. H. Hirst. Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. J. Biol. Chem. 268:14991-14997 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 14991-14997
-
-
Hunter, J.1
Jepson, M.A.2
Tsuruo, T.3
Simmons, N.L.4
Hirst, B.H.5
-
15
-
-
0027730961
-
Evidence for a polarized efflux system in Caco-2 cells capable of modulating cyclosporin a transport
-
Augustijns, P. F., T. P. Bradshaw, L.-S. L. Gan, R. W. Hendren, and D. R. Thakker. Evidence for a polarized efflux system in Caco-2 cells capable of modulating cyclosporin A transport. Biochem. Biophys. Res. Commun. 197:360-365 (1993).
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.197
, pp. 360-365
-
-
Augustijns, P.F.1
Bradshaw, T.P.2
Gan, L.-S.L.3
Hendren, R.W.4
Thakker, D.R.5
-
16
-
-
0028905095
-
Angiotensin-converting enzyme (ACE) inhibitor transport in human intestinal epithelial (Caco-2) cells
-
Thwaites, D. T., M. Cavet, B. H. Hirst, and N. L. Simmons. Angiotensin-converting enzyme (ACE) inhibitor transport in human intestinal epithelial (Caco-2) cells. Br. J. Pharmacol. 114:981-986 (1995).
-
(1995)
Br. J. Pharmacol.
, vol.114
, pp. 981-986
-
-
Thwaites, D.T.1
Cavet, M.2
Hirst, B.H.3
Simmons, N.L.4
-
17
-
-
0028110184
-
Expression of cytochrome P-450 3A in HT29-MTX cells and Caco-2 clone TC7
-
Published erratum in FEBS Lett. 362:99 (1995)
-
Carriere, V., T. Lesuffleur, A. Barbat, M. Rousset, E. Dussaulx, P. Costet, I. deWaziers, P. Beaune, and A. Zweibaum. Expression of cytochrome P-450 3A in HT29-MTX cells and Caco-2 clone TC7 [Published erratum in FEBS Lett. 362:99 (1995).] FEBS Lett. 355:247-250 (1994).
-
(1994)
FEBS Lett.
, vol.355
, pp. 247-250
-
-
Carriere, V.1
Lesuffleur, T.2
Barbat, A.3
Rousset, M.4
Dussaulx, E.5
Costet, P.6
DeWaziers, I.7
Beaune, P.8
Zweibaum, A.9
-
18
-
-
9044252313
-
CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells
-
Gan, L.-S. L., M. A. Moseley, B. Khosla, P. F. Augustijns, T. P. Bradshaw, R. W. Hendren, and D. R. Thakker. CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells. Drug Metab. Dispos. 24:344-349 (1996).
-
(1996)
Drug Metab. Dispos.
, vol.24
, pp. 344-349
-
-
Gan, L.-S.L.1
Moseley, M.A.2
Khosla, B.3
Augustijns, P.F.4
Bradshaw, T.P.5
Hendren, R.W.6
Thakker, D.R.7
-
19
-
-
0026981085
-
Regulation of cytochrome P450IA1 gene expression in a human intestinal cell line, Caco-2
-
Boulenc, X., M. Bourrie, I. Fabre, C. Roque, H. Joyeux, Y. Berger, and G. Fahre. Regulation of cytochrome P450IA1 gene expression in a human intestinal cell line, Caco-2. J. Pharmacol. Exp. Ther. 263:1471-1478 (1992).
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.263
, pp. 1471-1478
-
-
Boulenc, X.1
Bourrie, M.2
Fabre, I.3
Roque, C.4
Joyeux, H.5
Berger, Y.6
Fahre, G.7
-
20
-
-
0038985073
-
Cell culture on a microscopically transparent microporous membrane
-
Pitt, A. M., J. E. Gabriels, F. Badmington, J. McDowell, L. Gonzales, and M. E. Waugh. Cell culture on a microscopically transparent microporous membrane. Biotechniques 5:162-171 (1987).
-
(1987)
Biotechniques
, vol.5
, pp. 162-171
-
-
Pitt, A.M.1
Gabriels, J.E.2
Badmington, F.3
McDowell, J.4
Gonzales, L.5
Waugh, M.E.6
-
21
-
-
0023490564
-
Polarized secretion of newly synthesized lipoproteins by the Caco-2 human intestinal cell line
-
Traber, M. G., H. J. Kayden, and M. J. Rindler. Polarized secretion of newly synthesized lipoproteins by the Caco-2 human intestinal cell line. J. Lipid Res. 28:1350-1363 (1987).
-
(1987)
J. Lipid Res.
, vol.28
, pp. 1350-1363
-
-
Traber, M.G.1
Kayden, H.J.2
Rindler, M.J.3
-
22
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254 (1976).
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
23
-
-
0028113492
-
Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel
-
published erratum appears in Drug Metab. Dispos. 23(3) (1995).
-
Lown, K. S., J. C. Kolars, K. E. Thummel, J. L. Barnett, K. L. Kunze, S. A. Wrighton, and P. B. Watkins. Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Drug Metab. Dispos. 22:947-955 (1994) [published erratum appears in Drug Metab. Dispos. 23(3) (1995).].
-
(1994)
Drug Metab. Dispos.
, vol.22
, pp. 947-955
-
-
Lown, K.S.1
Kolars, J.C.2
Thummel, K.E.3
Barnett, J.L.4
Kunze, K.L.5
Wrighton, S.A.6
Watkins, P.B.7
-
24
-
-
0022220067
-
Monoclonal antibodies against human liver cytochrome P-450
-
Beaune, P., P. Kremers, F. Letawe-Goujon, and J. E. Gielen. Monoclonal antibodies against human liver cytochrome P-450. Biochem. Pharmacol. 34:3547-3552 (1985).
-
(1985)
Biochem. Pharmacol.
, vol.34
, pp. 3547-3552
-
-
Beaune, P.1
Kremers, P.2
Letawe-Goujon, F.3
Gielen, J.E.4
-
25
-
-
0025161416
-
Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3)
-
Wrighton, S. A., W. R. Brian, M.-A. Sari, M. Iwasaki, F. P. Guengerich, J. L. Raucy, D. T. Molowa, and M. Vandenbranden. Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3). Mol. Pharmacol. 38:207-213 (1990).
-
(1990)
Mol. Pharmacol.
, vol.38
, pp. 207-213
-
-
Wrighton, S.A.1
Brian, W.R.2
Sari, M.-A.3
Iwasaki, M.4
Guengerich, F.P.5
Raucy, J.L.6
Molowa, D.T.7
Vandenbranden, M.8
-
26
-
-
0029073965
-
Antipeptide antibodies against overlapping sequences differentially inhibit human CYP2D6
-
Cribb, A., C. Nuss, and R. Wang. Antipeptide antibodies against overlapping sequences differentially inhibit human CYP2D6. Drug Metab. Dispos. 23:671-675 (1995).
-
(1995)
Drug Metab. Dispos.
, vol.23
, pp. 671-675
-
-
Cribb, A.1
Nuss, C.2
Wang, R.3
-
27
-
-
0026020325
-
Inhibition and activation of acetaminophen reactive metabolite formation by caffeine: Roles of cytochromes P-450 IA1 and IIIA2
-
Lee, C. A., K. E. Thummel, T. F. Kalhorn, S. D. Nelson, and J. T. Slattery. Inhibition and activation of acetaminophen reactive metabolite formation by caffeine: roles of cytochromes P-450 IA1 and IIIA2. Drug Metab. Dispos. 19:348-353 (1991).
-
(1991)
Drug Metab. Dispos.
, vol.19
, pp. 348-353
-
-
Lee, C.A.1
Thummel, K.E.2
Kalhorn, T.F.3
Nelson, S.D.4
Slattery, J.T.5
-
28
-
-
0027253615
-
Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4
-
Thummel, K. E., C. A. Lee, K. L. Kunze, S. D. Nelson, and J. T. Slattery. Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4. Biochem. Pharmacol. 45:1563-1569 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 1563-1569
-
-
Thummel, K.E.1
Lee, C.A.2
Kunze, K.L.3
Nelson, S.D.4
Slattery, J.T.5
-
29
-
-
0027241257
-
Human alfentanil metabolism by cytochrome P450 3A3/4. An explanation for the interindividual variability in alfentanil clearance?
-
Kharasch, E. D., and K. E. Thummel. Human alfentanil metabolism by cytochrome P450 3A3/4. An explanation for the interindividual variability in alfentanil clearance? Anesth. Analg. 76:1033-1039 (1993).
-
(1993)
Anesth. Analg.
, vol.76
, pp. 1033-1039
-
-
Kharasch, E.D.1
Thummel, K.E.2
-
30
-
-
0025242834
-
Liver fatty acid-binding protein: A cellular marker for studying cellular differentiation in gut epithelial neoplasms
-
Carroll, S. L., K. A. Roth, and J. I. Gordon. Liver fatty acid-binding protein: a cellular marker for studying cellular differentiation in gut epithelial neoplasms. Gastroenterology 99:1727-1735 (1990).
-
(1990)
Gastroenterology
, vol.99
, pp. 1727-1735
-
-
Carroll, S.L.1
Roth, K.A.2
Gordon, J.I.3
-
31
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159 (1987).
-
(1987)
Anal. Biochem.
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
32
-
-
0027282761
-
Cultured adult rat jejunal explants as a model for studying regulation of CYP3A
-
Schmiedlin-Ren, P., P. E. Benedict, W. O. III Dobbins, M. Ghosh, J. C. Kolars, and P. B. Watkins. Cultured adult rat jejunal explants as a model for studying regulation of CYP3A. Biochem. Pharmacol. 46:905-918 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 905-918
-
-
Schmiedlin-Ren, P.1
Benedict, P.E.2
Dobbins III, W.O.3
Ghosh, M.4
Kolars, J.C.5
Watkins, P.B.6
-
33
-
-
0028063131
-
CYP3A gene expression in human gut epithelium
-
Kolars, J. C., K. S. Lown, P. Schmiedlin-Ren, M. Ghosh, C. Fang, S. A. Wrighton, R. M. Merion, and P. B. Watkins. CYP3A gene expression in human gut epithelium. Pharmacogenetics 4:247-259 (1994).
-
(1994)
Pharmacogenetics
, vol.4
, pp. 247-259
-
-
Kolars, J.C.1
Lown, K.S.2
Schmiedlin-Ren, P.3
Ghosh, M.4
Fang, C.5
Wrighton, S.A.6
Merion, R.M.7
Watkins, P.B.8
-
34
-
-
0025191307
-
Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins
-
Chen, C., D. Clark, K. Ueda, I. Pastan, M. M. Gottesman, and I. B. Roninson. Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins. J. Biol. Chem. 265:506-514 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 506-514
-
-
Chen, C.1
Clark, D.2
Ueda, K.3
Pastan, I.4
Gottesman, M.M.5
Roninson, I.B.6
-
35
-
-
0023620236
-
The human and rodent intestinal fatty acid binding protein genes
-
Sweetser, D. A., E. H. Birkenmeier, I. J. Klisak, S. Zollman, R. S. Sparkes, T. Mohandas, A. J. Lusis, and J. I. Gordon. The human and rodent intestinal fatty acid binding protein genes. J. Biol. Chem. 262:16060-16071 (1987).
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 16060-16071
-
-
Sweetser, D.A.1
Birkenmeier, E.H.2
Klisak, I.J.3
Zollman, S.4
Sparkes, R.S.5
Mohandas, T.6
Lusis, A.J.7
Gordon, J.I.8
-
36
-
-
0023812318
-
Sequence of human villin: A large duplicated domain homologous with other actin-severing proteins and a unique small carboxy-terminal domain related to villin specificity
-
Arpin, M., E. Pringault, J. Finidori, A. Garcia, J.-M. Jeltsch, J. Vandekerckhove, and D. Louvard. Sequence of human villin: a large duplicated domain homologous with other actin-severing proteins and a unique small carboxy-terminal domain related to villin specificity. J. Cell Biol. 107: 1759-1766 (1988).
-
(1988)
J. Cell Biol.
, vol.107
, pp. 1759-1766
-
-
Arpin, M.1
Pringault, E.2
Finidori, J.3
Garcia, A.4
Jeltsch, J.-M.5
Vandekerckhove, J.6
Louvard, D.7
-
38
-
-
0027137429
-
Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers, and its transcriptional control
-
Hashimoto, H., K. Toide, R. Kitamura, M. Fujita, S. Tagawa, S. Itoh, and T. Kamataki. Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers, and its transcriptional control. Eur. J. Biochem. 218:585-595 (1993).
-
(1993)
Eur. J. Biochem.
, vol.218
, pp. 585-595
-
-
Hashimoto, H.1
Toide, K.2
Kitamura, R.3
Fujita, M.4
Tagawa, S.5
Itoh, S.6
Kamataki, T.7
-
39
-
-
0026538997
-
Genomic organization of human fetal specific P-450 IIIA7 (cytochrome P-450HFLa)-related gene(s) and interaction of transcriptional regulatory factor with its DNA element in the 5′ flanking region
-
Itoh, S., T. Yanagimoto, S. Tagawa, H. Hashimoto, R. Kitamura, Y. Nakajima, T. Okochi, S. Fujimoto, J. Uchino, and T. Kamataki. Genomic organization of human fetal specific P-450 IIIA7 (cytochrome P-450HFLa)-related gene(s) and interaction of transcriptional regulatory factor with its DNA element in the 5′ flanking region. Biochim. Biophys. Acta 1130:133-138 (1992).
-
(1992)
Biochim. Biophys. Acta
, vol.1130
, pp. 133-138
-
-
Itoh, S.1
Yanagimoto, T.2
Tagawa, S.3
Hashimoto, H.4
Kitamura, R.5
Nakajima, Y.6
Okochi, T.7
Fujimoto, S.8
Uchino, J.9
Kamataki, T.10
-
41
-
-
0024352638
-
Absolute mRNa quantification using the polymerase chain reaction (PCR): A novel approach by a PCR aided transcript titration assay (PATTY)
-
Becker-Andre, M., and K. Hahlbrock. Absolute mRNA quantification using the polymerase chain reaction (PCR): a novel approach by a PCR aided transcript titration assay (PATTY). Nucleic Acids Res. 17:9437-9446 (1989).
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 9437-9446
-
-
Becker-Andre, M.1
Hahlbrock, K.2
-
42
-
-
0025355882
-
Analysis of cytokine mRNA and DNA: Detection and quantitation by competitive polymerase chain reaction
-
Gilliland, G., S. Perrin, K. Blanchard, and H. F. Bunn. Analysis of cytokine mRNA and DNA: Detection and quantitation by competitive polymerase chain reaction. Proc. Natl. Acad. Sci. USA 87:2725-2729 (1990).
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 2725-2729
-
-
Gilliland, G.1
Perrin, S.2
Blanchard, K.3
Bunn, H.F.4
-
43
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
Lowry, O. H., N. J. Rosebrough, A. L. Farr, and R. J. Randall. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265-275 (1951).
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
44
-
-
9044254525
-
P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
-
Nelson, D. R., L. Koymans, T. Kamataki, J. J. Stegeman, R. Feyereisen, D. J. Waxman, M. R. Waterman, O. Gotoh, M. J. Coon, R. W. Estabrook, I. C. Gunsalus, and D. W. Nebert. P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics 6:1-42 (1996).
-
(1996)
Pharmacogenetics
, vol.6
, pp. 1-42
-
-
Nelson, D.R.1
Koymans, L.2
Kamataki, T.3
Stegeman, J.J.4
Feyereisen, R.5
Waxman, D.J.6
Waterman, M.R.7
Gotoh, O.8
Coon, M.J.9
Estabrook, R.W.10
Gunsalus, I.C.11
Nebert, D.W.12
-
45
-
-
0024373348
-
Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4
-
Kronbach, T., D. Mathys, M. Umeno, F. J. Gonzalez, and U. A. Meyer. Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4. Mol. Pharmacol. 36:89-96 (1989).
-
(1989)
Mol. Pharmacol.
, vol.36
, pp. 89-96
-
-
Kronbach, T.1
Mathys, D.2
Umeno, M.3
Gonzalez, F.J.4
Meyer, U.A.5
-
46
-
-
0029028792
-
Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
-
Wacher, V. J., C.-Y. Wu, and L. Z. Benet. Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy. Mol. Carcinog. 13:129-134 (1995).
-
(1995)
Mol. Carcinog.
, vol.13
, pp. 129-134
-
-
Wacher, V.J.1
Wu, C.-Y.2
Benet, L.Z.3
-
47
-
-
0030059953
-
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells
-
Schuetz, E. G., W. T. Beck, and J. D. Schuetz. Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. Mol. Pharmacol. 49:311-318 (1996).
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 311-318
-
-
Schuetz, E.G.1
Beck, W.T.2
Schuetz, J.D.3
-
48
-
-
0028294978
-
Effects of 1,25-dihydroxyvitamin D3 on proliferation and differentiation of Caco-2 cells
-
Halline, A. G., N. O. Davidson, S. F. Skarosi, M. D. Sitrin, C. Tietze, D. H. Alpers, and T. A. Brasitus. Effects of 1,25-dihydroxyvitamin D3 on proliferation and differentiation of Caco-2 cells. Endocrinology 134:1710-1717 (1994).
-
(1994)
Endocrinology
, vol.134
, pp. 1710-1717
-
-
Halline, A.G.1
Davidson, N.O.2
Skarosi, S.F.3
Sitrin, M.D.4
Tietze, C.5
Alpers, D.H.6
Brasitus, T.A.7
-
49
-
-
0028234586
-
Regioselective biotransformation of midazolam by members of the human P450 3A (CYP3A) subfamily
-
Gorski, J. C., S. D. Hall, D. R. Jones, M. Vandenbranden, and S. A. Wrighton. Regioselective biotransformation of midazolam by members of the human P450 3A (CYP3A) subfamily. Biochem. Pharmacol. 47:1643-1653 (1994).
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 1643-1653
-
-
Gorski, J.C.1
Hall, S.D.2
Jones, D.R.3
Vandenbranden, M.4
Wrighton, S.A.5
-
50
-
-
0027306831
-
Extracellular matrix regulation of multidrug resistance in primary monolayer cultures of adult rat hepatocytes
-
Schuetz, J. D., and E. G. Schuetz. Extracellular matrix regulation of multidrug resistance in primary monolayer cultures of adult rat hepatocytes. Cell Growth Differ. 4:31-40 (1993).
-
(1993)
Cell Growth Differ.
, vol.4
, pp. 31-40
-
-
Schuetz, J.D.1
Schuetz, E.G.2
-
51
-
-
0029998275
-
Comparative studies of drug-metabolizing enzymes in dog, monkey, and human small intestines, and in Caco-2 cells
-
Prueksaritanont, T., L. M. Gorham, J. H. Hochman, L. O. Tran, and K. P. Vyas. Comparative studies of drug-metabolizing enzymes in dog, monkey, and human small intestines, and in Caco-2 cells. Drug Metab. Dispos. 24:634-642 (1996).
-
(1996)
Drug Metab. Dispos.
, vol.24
, pp. 634-642
-
-
Prueksaritanont, T.1
Gorham, L.M.2
Hochman, J.H.3
Tran, L.O.4
Vyas, K.P.5
-
52
-
-
0026575081
-
Trafficking of exogenous fatty acids within Caco-2 cells
-
Levin, M. S., V. D. Talkad, J. I. Gordon, and W. F. Stenson. Trafficking of exogenous fatty acids within Caco-2 cells. J. Lipid Res. 33:9-19 (1992).
-
(1992)
J. Lipid Res.
, vol.33
, pp. 9-19
-
-
Levin, M.S.1
Talkad, V.D.2
Gordon, J.I.3
Stenson, W.F.4
-
53
-
-
0027050850
-
Newly identified actions of the vitamin D endocrine system
-
Walters, M. W. Newly identified actions of the vitamin D endocrine system. Endocr. Rev. 13:719-764 (1992).
-
(1992)
Endocr. Rev.
, vol.13
, pp. 719-764
-
-
Walters, M.W.1
-
54
-
-
0026583522
-
3, a steroid hormone that produces biologic effects via both genomic and nongenomic pathways
-
3, a steroid hormone that produces biologic effects via both genomic and nongenomic pathways. J. Steroid Biochem. Mol. Biol. 41:231-240 (1992).
-
(1992)
J. Steroid Biochem. Mol. Biol.
, vol.41
, pp. 231-240
-
-
Norman, A.W.1
Nemere, I.2
Zhou, L.-X.3
Bishop, J.E.4
Lowe, K.E.5
Maiyar, A.C.6
Collins, E.D.7
Taoka, T.8
Sergeev, I.9
Farach-Carson, M.C.10
-
55
-
-
0027230170
-
Regulation of development and differentiation by the extracellular matrix
-
Adams, J. C., and F. M. Watt. Regulation of development and differentiation by the extracellular matrix. Development 117:1183-1198 (1993).
-
(1993)
Development
, vol.117
, pp. 1183-1198
-
-
Adams, J.C.1
Watt, F.M.2
-
56
-
-
0029899741
-
Regulation of human (Caco-2) intestinal epithelial cell differentiation by extracellular matrix proteins
-
Basson, M. D., G. Turowski, and N. J. Emenaker. Regulation of human (Caco-2) intestinal epithelial cell differentiation by extracellular matrix proteins. Exp. Cell Res. 225:301-305 (1996).
-
(1996)
Exp. Cell Res.
, vol.225
, pp. 301-305
-
-
Basson, M.D.1
Turowski, G.2
Emenaker, N.J.3
-
57
-
-
0026731712
-
Apolipoprotein expression and cellular differentiation in Caco-2 intestinal cells
-
Wagner, R. D., E. S. Krul, J. B. Moberly, D. H. Alpers, and G. Schonfeld. Apolipoprotein expression and cellular differentiation in Caco-2 intestinal cells. Am. J. Physiol. 263 (2 Part 1) :E374-E382 (1992).
-
(1992)
Am. J. Physiol.
, vol.263
, Issue.2 PART 1
-
-
Wagner, R.D.1
Krul, E.S.2
Moberly, J.B.3
Alpers, D.H.4
Schonfeld, G.5
-
58
-
-
0025897379
-
Characterization of the vitamin D receptor from the Caco-2 human colon carcinoma cell line: Effect of cellular differentiation
-
Giuliano, A. R., R. T. Franceschi, and R. J. Wood. Characterization of the vitamin D receptor from the Caco-2 human colon carcinoma cell line: effect of cellular differentiation. Arch. Biochem. Biophys. 285:261-269 (1991).
-
(1991)
Arch. Biochem. Biophys.
, vol.285
, pp. 261-269
-
-
Giuliano, A.R.1
Franceschi, R.T.2
Wood, R.J.3
-
59
-
-
0028982622
-
Cloning of the human 1alpha,25-dihydroxyvitamin D-3 24-hydroxylase gene promoter and identification of two vitamin D-responsive elements
-
Chen, K.-S., and H. F. DeLuca. Cloning of the human 1alpha,25-dihydroxyvitamin D-3 24-hydroxylase gene promoter and identification of two vitamin D-responsive elements. Biochim. Biophys. Acta 1263:1-9 (1995).
-
(1995)
Biochim. Biophys. Acta
, vol.1263
, pp. 1-9
-
-
Chen, K.-S.1
DeLuca, H.F.2
-
60
-
-
0025678705
-
The vitamin D-responsive element in the human osteocalcin gene
-
Ozono, K., J. Liao, S. A. Kerner, R. A. Scott, and J. W. Pike. The vitamin D-responsive element in the human osteocalcin gene. J. Biol. Chem. 265: 21881-21888 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 21881-21888
-
-
Ozono, K.1
Liao, J.2
Kerner, S.A.3
Scott, R.A.4
Pike, J.W.5
-
61
-
-
0242566968
-
Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3
-
Kerner, S. A., R. A. Scott, and J. W. Pike. Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3. Proc. Natl. Acad. Sci. USA 86:4455-1459 (1989).
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 4455-11459
-
-
Kerner, S.A.1
Scott, R.A.2
Pike, J.W.3
-
62
-
-
0024351706
-
1,25-Dihydroxyvitamin D-responsive element and glucocorticoid repression in the osteocalcin gene
-
Morrison, N. A., J. Shine, J.-C. Fragonas, V. Verkest, M. L. McMenemy, and J. A. Eisman. 1,25-Dihydroxyvitamin D-responsive element and glucocorticoid repression in the osteocalcin gene. Science (Washington D. C.) 246:1158-1161 (1989).
-
(1989)
Science (Washington D. C.)
, vol.246
, pp. 1158-1161
-
-
Morrison, N.A.1
Shine, J.2
Fragonas, J.-C.3
Verkest, V.4
McMenemy, M.L.5
Eisman, J.A.6
-
63
-
-
0026693809
-
Sequences in the human parathyroid gene that bind the 1,25-dihydroxyvitamin D3 receptor and mediate transcriptional repression in response to 1,25-dihydroxyvitamin D3
-
Demay, M. B., M. S. Kiernan, H. F. DeLuca, and H. M. Kronenberg. Sequences in the human parathyroid gene that bind the 1,25-dihydroxyvitamin D3 receptor and mediate transcriptional repression in response to 1,25-dihydroxyvitamin D3. Proc. Natl. Acad. Sci. USA 89:8097-8101 (1992).
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 8097-8101
-
-
Demay, M.B.1
Kiernan, M.S.2
DeLuca, H.F.3
Kronenberg, H.M.4
-
64
-
-
0029906308
-
Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif
-
Huss, J. M., S. I. Wang, A. Astrom, P. McQuiddy, and C. B. Kasper. Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif. Proc. Natl. Acad. Sci. USA 93:4666-4670 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4666-4670
-
-
Huss, J.M.1
Wang, S.I.2
Astrom, A.3
McQuiddy, P.4
Kasper, C.B.5
-
65
-
-
0029992789
-
Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes
-
Barwick, J. L., L. C. Quattrochi, A. S. Mills, C. Potenza, R. H. Tukey, and P. S. Guzelian. Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes. Mol. Pharmacol. 50:10-16 (1996).
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 10-16
-
-
Barwick, J.L.1
Quattrochi, L.C.2
Mills, A.S.3
Potenza, C.4
Tukey, R.H.5
Guzelian, P.S.6
-
66
-
-
1842363019
-
-
Deleted in proof
-
Deleted in proof.
-
-
-
-
67
-
-
0026650170
-
Polarized efflux of 2′,7′-bis(2-carboxyethyl)-5(6)-carboxyfluorescein from cultured epithelial cell monolayers
-
Collington, G. K., J. Hunter, C. N. Allen, N. L. Simmons, and B. H. Hirst. Polarized efflux of 2′,7′-bis(2-carboxyethyl)-5(6)-carboxyfluorescein from cultured epithelial cell monolayers. Biochem. Pharmacol. 44:417-424 (1992).
-
(1992)
Biochem. Pharmacol.
, vol.44
, pp. 417-424
-
-
Collington, G.K.1
Hunter, J.2
Allen, C.N.3
Simmons, N.L.4
Hirst, B.H.5
-
68
-
-
0025134337
-
Cyclosporin a drug interactions: Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin a oxidase) in primary cultures of human hepatocytes and in liver microsomes
-
Pichard, L., I. Fabre, G. Fabre, J. Domergue, B. Saint Aubert, G. Mourad, and P. Maurel. Cyclosporin A drug interactions: screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes. Drug Metab. Dispos. 18: 595-606 (1990).
-
(1990)
Drug Metab. Dispos.
, vol.18
, pp. 595-606
-
-
Pichard, L.1
Fabre, I.2
Fabre, G.3
Domergue, J.4
Saint Aubert, B.5
Mourad, G.6
Maurel, P.7
-
69
-
-
0028001350
-
The high-level expression in Escherichia coli of the membrane-bound form of human and rat cytochrome b5 and studies on their mechanism and function
-
Holmans, P. L., M. S. Shet, C. A. Martin-Wixtrom, C. W. Fisher, and R. W. Estabrook. The high-level expression in Escherichia coli of the membrane-bound form of human and rat cytochrome b5 and studies on their mechanism and function. Arch. Biochem. Biophys. 312:554-565 (1994).
-
(1994)
Arch. Biochem. Biophys.
, vol.312
, pp. 554-565
-
-
Holmans, P.L.1
Shet, M.S.2
Martin-Wixtrom, C.A.3
Fisher, C.W.4
Estabrook, R.W.5
-
70
-
-
0026612528
-
Expression of cytochrome b5 in yeast and characterization of mutants of the membrane-anchoring domain
-
Vergeres, G., and L. Waskell. Expression of cytochrome b5 in yeast and characterization of mutants of the membrane-anchoring domain. J. Biol. Chem. 267:12583-12591 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 12583-12591
-
-
Vergeres, G.1
Waskell, L.2
|