Induction of CYP3A4 by 1α,25-dihydroxyvitamin D3 is human cell linespecific and is unlikely to involve pregnane X receptor

Drug Metabolism and Disposition

Volumn 29, Issue 11, 2001, Pages 1446-1453

  Schmiedlin Ren, Phyllissa ^a   Thummel, Kenneth E ^b   Fisher, Jeannine M ^b,d   Paine, Mary F ^c   Watkins, Paul B ^c,e  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d PFIZER INC   (United States)

^e UNIVERSITY OF NORTH CAROLINA HOSPITALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; CYTOCHROME P450 3A4; DEXAMETHASONE; DEXAMETHASONE DERIVATIVE; DEXAMETHASONE TERT BUTYL ACETATE; LIGAND; PREGNANE X RECEPTOR; RETINOIC ACID; RETINOIC ACID RECEPTOR; RIFAMPICIN; STEROID RECEPTOR; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

ARTICLE; CATALYSIS; CELL CULTURE; CELL LINE; CELL STRAIN CACO 2; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; ENZYME ACTIVITY; ENZYME INDUCTION; HUMAN; HUMAN CELL; LIVER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CACO-2 CELLS; CALCITRIOL; CALCIUM CHANNEL AGONISTS; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; HEPATOCYTES; HUMANS; MIXED FUNCTION OXYGENASES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID;

EID: 0034776256     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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