Combinatorial protein biochemistry for therapeutics and proteomics

Current Pharmaceutical Biotechnology

Volumn 5, Issue 1, 2004, Pages 17-27

  Lowe, David ^a   Jermutus, Lutz ^a  

^a MEDIMMUNE LTD   (United Kingdom)

Author keywords

Alternative frameworks; Directed evolution; Display; Protein engineering; Protein therapeutic

Indexed keywords

ABT 874; ABTHRAX; ACTIVATED PROTEIN C; ADALIMUMAB; ALPHA2A INTERFERON; ALPHA2B INTERFERON; ANTIBODY; BELIMUMAB; BERTILIMUMAB; BETA1A INTERFERON; BONE MORPHOGENETIC PROTEIN 2; DEATH RECEPTOR 5 MONOCLONAL ANTIBODY; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HUMAN GROWTH HORMONE; INSULIN; INTERFERON BETA SERINE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 11; INTERLEUKIN 2; LERDELIMUMAB; METELIMUMAB; MONOCLONAL ANTIBODY; OSTEOGENIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR 2 MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIBODY AFFINITY; ANTIBODY LIBRARY; BIOTECHNOLOGY; COMBINATORIAL CHEMISTRY; DRUG INDICATION; DRUG RESEARCH; DRUG SCREENING; DRUG TARGETING; GENETIC ENGINEERING; GENETIC RECOMBINATION; HIGH THROUGHPUT SCREENING; HUMAN; IMMUNE RESPONSE; IMMUNIZATION; MUTAGENESIS; NONHUMAN; PHAGE DISPLAY; PROTEOMICS; REVIEW; RIBOSOME;

ANIMALS; COMBINATORIAL CHEMISTRY TECHNIQUES; HUMANS; PROTEOMICS; RECOMBINANT PROTEINS;

EID: 1642483468     PISSN: 13892010     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389201043489585     Document Type: Review

References (94)

1. Griffiths, A. D. and Duncan, A. R. (1998) Curr. Opin. Biotechnol. 9, 102-8.
2. Kretzschmar, T. and von Rüden, T. (2002) Curr. Opin. Biotechnol. 13, 598-602.
3. McCafferty, J., Griffiths, A. D., Winter, G. and Chiswell, D. J. (1990) Nature 348, 552-4.
4. O'Connell, D., Becerril, B., Roy-Burman, A., Daws, M. and Marks, J. D. (2002) J. Mol. Biol. 321, 49-56.
5. Vaughan, T. J., Williams, A. J., Pritchard, K., Osbourn, J. K., Pope, A. R., Earnshaw, J. C., McCafferty, J., Hodits, R. A., Wilton, J. and Johnson, K. S. (1996) Nat. Biotechnol. 14, 309-14.
6. de Haard, H. J., van Neer, N., Reurs, A., Hufton, S. E., Roovers, R. C., Henderikx, P., de Bruine, A. P., Arends, J. W. and Hoogenboom, H. R. (1999) J. Biol. Chem. 274, 18218-30.
7. Knappik, A., Ge, L., Honegger, A., Pack, P., Fischer, M., Wellnhofer, G., Hoess, A., Wolle, J., Plückthun, A. and Virnekas, B. (2000) J. Mol. Biol. 296, 57-86.
8. Barbas, C. F., 3rd & Burton, D. R. (1996) Trends. Biotechnol. 14, 230-4.
9. Roben, P., Barbas, S. M., Sandoval, L., Lecerf, J. M., Stollar, B. D., Solomon, A. and Silverman, G. J. (1996) J. Clin. Invest. 98, 2827-37.
10. Roovers, R. C., van der Linden, E., Zijlema, H., de Bruine, A., Arends, J. W. and Hoogenboom, H. R. (2001) Int. J. Cancer 93, 832-40.
11. Soderlind, E., Strandberg, L., Jirholt, P., Kobayashi, N., Alexeiva, V., Aberg, A. M., Nilsson, A., Jansson, B., Ohlin, M., Wingren, C., Danielsson, L., Carlsson, R. and Borrebaeck, C. A. (2000) Nat. Biotechnol. 18, 852-6.
12. Hoogenboom, H. R. and Winter, G. (1992) J. Mol. Biol. 227, 381-8.
13. Griffiths, A. D., Williams, S. C., Hartley, O., Tomlinson, I. M., Waterhouse, P., Crosby, W. L., Kontermann, R. E., Jones, P. T., Low, N. M., Allison, T. J. and et al. (1994) EMBO J. 13, 3245-60.
14. Rauchenberger, R., Borges, E., Thomassen-Wolf, E., Rom, E., Adar, R., Yaniv, Y., Malka, M., Chumakov, I., Kotzer, S., Resnitzky, D., Knappik, A., Reiffert, S., Prassler, J., Jury, K., Waldherr, D., Bauer, S., Kretzschmar, T., Yayon, A. and Rothe, C. (2003) J. Biol. Chem.
15. Hawkins, R. E., Russell, S. J. and Winter, G. (1992) J. Mol. Biol. 226, 889-96.
16. Schier, R., McCall, A., Adams, G. P., Marshall, K. W., Merritt, H., Yim, M., Crawford, R. S., Weiner, L. M., Marks, C. and Marks, J. D. (1996) J. Mol. Biol. 263, 551-67.
17. Glaser, S. M., Yelton, D. E. and Huse, W. D. (1992) J. Immunol. 149, 3903-13.
18. Virnekas, B., Ge, L., Plückthun, A., Schneider, K. C., Wellnhofer, G. and Moroney, S. E. (1994) Nucleic Acids Res. 22, 5600-7.
19. Balint, R. F. and Larrick, J. W. (1993) Gene 137, 109-18.
20. Low, N. M., Holliger, P. H. and Winter, G. (1996) J. Mol. Biol. 260, 359-68.
21. Jespers, L. S., Roberts, A., Mahler, S. M., Winter, G. and Hoogenboom, H. R. (1994) Biotechnology (NY) 12, 899-903.
22. Mattheakis, L. C., Bhatt, R. R. and Dower, W. J. (1994) Proc. Natl. Acad. Sci. USA 91, 9022-6.
23. Hanes, J. and Plückthun, A. (1997) Proc. Natl. Acad. Sci. USA 94, 4937-42.
24. He, M., Menges, M., Groves, M. A., Corps, E., Liu, H., Bruggemann, M. and Taussig, M. J. (1999) J. Immunol. Methods 231, 105-17.
25. Amstutz, P., Forrer, P., Zahnd, C. and Plückthun, A. (2001) Curr. Opin. Biotechnol. 12, 400-5.
26. Hanes, J., Schaffitzel, C., Knappik, A. and Plückthun, A. (2000) Nat. Biotechnol. 18, 1287-92.
27. Jermutus, L., Honegger, A., Schwesinger, F., Hanes, J. and Plückthun, A. (2001) Proc. Natl. Acad. Sci. USA 98, 75-80.
28. Boder, E. T. and Wittrup, K. D. (1997) Nat. Biotechnol. 15, 553-7.
29. Boder, E. T., Midelfort, K. S. and Wittrup, K. D. (2000) Proc. Natl. Acad. Sci. USA 97, 10701-5.
30. Shusta, E. V., Holler, P. D., Kieke, M. C., Kranz, D. M. and Wittrup, K. D. (2000) Nat. Biotechnol. 18, 754-9.
31. Holler, P. D., Holman, P. O., Shusta, E. V., O'Herrin, S., Wittrup, K. D. and Kranz, D. M. (2000) Proc. Natl. Acad. Sci. USA 97, 5387-92.
32. Feldhaus, M. J., Siegel, R. W., Opresko, L. K., Coleman, J. R., Feldhaus, J. M., Yeung, Y. A., Cochran, J. R., Heinzelman, P., Colby, D., Swers, J., Graff, C., Wiley, H. S. and Wittrup, K. D. (2003) Nat. Biotechnol. 21, 163-70.
33. Lee, S. Y., Choi, J. H. and Xu, Z. (2003) Trends. Biotechnol. 21, 45-52.
34. Chen, G., Hayhurst, A., Thomas, J. G., Harvey, B. R., Iverson, B. L. and Georgiou, G. (2001) Nat. Biotechnol. 19, 537-42.
35. Walsh, G. (2003) Nat. Biotechnol. 21, 865-70.
36. Griffiths, A. D. and Tawfik, D. S. (2000) Curr. Opin. Biotechnol. 11, 338-53.
37. Pedersen, H., Holder, S., Sutherlin, D. P., Schwitter, U., King, D. S. and Schultz, P. G. (1998) Proc. Natl. Acad. Sci. USA 95, 10523-8.
38. Atwell, S. and Wells, J. A. (1999) Proc. Natl. Acad. Sci. USA 96, 9497-502.
39. Demartis, S., Huber, A., Viti, F., Lozzi, L., Giovannoni, L., Neri, P., Winter, G. and Neri, D. (1999) J. Mol. Biol. 286, 617-33.
40. Cesaro-Tadic, S., Lagos, D., Honegger, A., Rickard, J. H., Partridge, L. J., Blackburn, G. M. and Plückthun, A. (2003) Nat. Biotechnol. 21, 679-85.
41. Olsen, M. J., Stephens, D., Griffiths, D., Daugherty, P., Georgiou, G. and Iverson, B. L. (2000) Nat. Biotechnol. 18, 1071-4.
42. Amstutz, P., Pelletier, J. N., Guggisberg, A., Jermutus, L., Cesaro-Tadic, S., Zahnd, C. and Plückthun, A. (2002) J. Am. Chem. Soc. 124, 9396-403.
43. Tawfik, D. S. and Griffiths, A. D. (1998) Nat. Biotechnol. 16, 652-6.
44. Ghadessy, F. J., Ong, J. L. and Holliger, P. (2001) Proc. Natl. Acad. Sci. USA 98, 4552-7.
45. Griffiths, A. D. and Tawfik, D. S. (2003) EMBO J. 22, 24-35.
46. Marshall, S. A., Lazar, G. A., Chirino, A. J. and Desjarlais, J. R. (2003) Drug Discov. Today 8, 212-21.
47. Lowman, H. B., Bass, S. H., Simpson, N. and Wells, J. A. (1991) Biochemistry 30, 10832-8.
48. Lowman, H. B. and Wells, J. A. (1993) J. Mol. Biol. 234, 564-78.
49. Yamamoto, Y., Tsutsumi, Y., Yoshioka, Y., Nishibata, T., Kobayashi, K., Okamoto, T., Mukai, Y., Shimizu, T., Nakagawa, S., Nagata, S. and Mayumi, T. (2003) Nat. Biotechnol. 21, 546-52.
50. Tang, D. C., DeVit, M. and Johnston, S. A. (1992) Nature 356, 152-4.
51. Attanasio, R., Pehler, K. and Scinicariello, F. (1997) FEMS Immunol. Med. MicroBiol. 17, 207-15.
52. Nissim, A., Hoogenboom, H. R., Tomlinson, I. M., Flynn, G., Midgley, C., Lane, D. and Winter, G. (1994) EMBO J. 13, 692-8.
53. Parsons, H. L., Earnshaw, J. C., Wilton, J., Johnson, K. S., Schueler, P. A., Mahoney, W. and McCafferty, J. (1996) Protein Eng 9, 1043-9.
54. Lou, J., Marzari, R., Verzillo, V., Ferrero, F., Pak, D., Sheng, M., Yang, C., Sblattero, D. and Bradbury, A. (2001) J. Immunol. Methods 253, 233-42.
55. Kipriyanov, S. M. (2002) Methods. Mol. Biol. 178, 333-41.
56. Wörn, A. and Plückthun, A. (2001) J. Mol. Biol. 305, 989-1010.
57. Knappik, A. and Plückthun, A. (1995) Protein Eng. 8, 81-9.
58. Wall, J. G. and Plückthun, A. (1999) Protein Eng. 12, 605-11.
59. Lindner, P., Bauer, K., Krebber, A., Nieba, L., Kremmer, E., Krebber, C., Honegger, A., Klinger, B., Mocikat, R. and Plückthun, A. (1997) Biotechniques 22, 140-9.
60. Goletz, S., Christensen, P. A., Kristensen, P., Blohm, D., Tomlinson, I., Winter, G. and Karsten, U. (2002) J. Mol. Biol. 315, 1087-97.
61. Krebs, B., Rauchenberger, R., Reiffert, S., Rothe, C., Tesar, M., Thomassen, E., Cao, M., Dreier, T., Fischer, D., Hoss, A., Inge, L., Knappik, A., Marget, M., Pack, P., Meng, X. Q., Schier, R., Sohlemann, P., Winter, J., Wolle, J. and Kretzschmar, T. (2001) J. Immunol. Methods 254, 67-84.
62. Edwards, B. Barash, S.C., Main, S.H., Choi, G.H., Minter, R., Ullrich, S., Williams, E., Du Fou, L., Wilton, J., Albert, V.R., Ruben, S.M., & Vaughan, T.J. (2003) J. Mol. Biol. in press.
63. Ewert, S., Huber, T., Honegger, A. and Plückthun, A. (2003) J. Mol. Biol. 325, 531-53.
64. Ewert, S., Honegger, A. and Plückthun, A. (2003) Biochemistry 42, 1517-28.
65. Visintin, M., Settanni, G., Maritan, A., Graziosi, S., Marks, J. D. and Cattaneo, A. (2002) J. Mol. Biol. 317, 73-83.
66. Mossner, E., Koch, H. and Plückthun, A. (2001) J. Mol. Biol. 308, 115-22.
67. Tanaka, T., Chung, G. T., Forster, A., Lobato, M. N. and Rabbitts, T. H. (2003) Nucleic Acids Res 31, e23.
68. Tse, E., Lobato, M. N., Forster, A., Tanaka, T., Chung, G. T. and Rabbitts, T. H. (2002) J. Mol. Biol. 317, 85-94.
69. Visintin, M., Tse, E., Axelson, H., Rabbitts, T. H. and Cattaneo, A. (1999) Proc. Natl. Acad. Sci. USA 96, 11723-8.
70. Auf der Maur, A., Escher, D. and Barberis, A. (2001) FEBS Lett. 508, 407-12.
71. Beck, S., Sakurai, T., Eustace, B. K., Beste, G., Schier, R., Rudert, F. and Jay, D. G. (2002) Proteomics 2, 247-55.
72. Schwalbach, G., Sibler, A. P., Choulier, L., Deryckere, F. and Weiss, E. (2000) Protein Expr. Purif. 18, 121-32.
73. Nizak, C., Monier, S., del Nery, E., Moutel, S., Goud, B. and Perez, F. (2003) Science 300, 984-7.
74. Renard, M., Belkadi, L., Hugo, N., England, P., Altschuh, D. and Bedouelle, H. (2002) J. Mol. Biol. 318, 429-42.
75. Renard, M., Belkadi, L. and Bedouelle, H. (2003) J. Mol. Biol. 326, 167-75.
76. Dooley, H., Flajnik, M. F. and Porter, A. J. (2003) Mol. Immunol. 40, 25-33.
77. Heyd, B., Pecorari, F., Collinet, B., Adjadj, E., Desmadril, M. and Minard, P. (2003) Biochemistry 42, 5674-83.
78. Skerra, A. (2001) J. Biotechnol. 74, 257-75.
79. Ewert, S., Cambillau, C., Conrath, K. and Plückthun, A. (2002) Biochemistry 41, 3628-36.
80. Binz, H. K., Stumpp, M. T., Forrer, P., Amstutz, P. and Plückthun, A. (2003) J. Mol. Biol. 332, 489-503.
81. Stumpp, M. T., Forrer, P., Binz, H. K. and Plückthun, A. (2003) J. Mol. Biol. 332, 471-87.
82. Forrer, P., Stumpp, M. T., Binz, H. K. and Plückthun, A. (2003) FEBS Lett. 539, 2-6.
83. Kohl, A., Binz, H. K., Forrer, P., Stumpp, M. T., Plückthun, A. and Grutter, M. G. (2003) Proc. Natl. Acad. Sci. USA 100, 1700-5.
84. Jermutus, L. and Pelletier, J. (2001) Curr. Opin. Biotechnol. 12, 331-3.
85. Wittrup, K. D. (2001) Curr. Opin. Biotechnol. 12, 395-9.
86. Fu, A. Y., Spence, C., Scherer, A., Arnold, F. H. and Quake, S. R. (1999) Nat. Biotechnol. 17, 1109-11.
87. Lagerkvist, A. C., Földes-Papp, Z., Persson, M. A. and Rigler, R. (2001) Protein Sci. 10, 1522-8.
88. Jermutus, L., Kolly, R., Foldes-Papp, Z., Hanes, J., Rigler, R. and Plückthun, A. (2002) Eur. Biophys. J. 31, 179-84.
89. Forster, A. C., Tan, Z., Nalam, M. N., Lin, H., Qu, H., Cornish, V. W. and Blacklow, S. C. (2003) Proc. Natl. Acad. Sci. USA 100, 6353-7.
90. Forster, A. C., Weissbach, H. and Blacklow, S. C. (2001) Anal. BioChem. 297, 60-70.
91. Shimizu, Y., Inoue, A., Tomari, Y., Suzuki, T., Yokogawa, T., Nishikawa, K. and Ueda, T. (2001) Nat. Biotechnol. 19, 751-5.
92. Gartner, Z. J., Kanan, M. W. and Liu, D. R. (2002) J. Am. Chem. Soc. 124, 10304-6.
93. Gartner, Z. J. and Liu, D. R. (2001) J. Am. Chem. Soc. 123, 6961-3.
94. Calderone, C. T., Puckett, J. W., Gartner, Z. J. and Liu, D. R. (2002) Angew. Chem. Int. Ed. Engl. 41, 4104-8.