High-throughput generation and engineering of recombinant human antibodies

Journal of Immunological Methods

Volumn 254, Issue 1-2, 2001, Pages 67-84

  Krebs, Barbara ^a   Rauchenberger, Robert ^a   Reiffert, Silke ^a   Rothe, Christine ^a   Tesar, Michael ^a   Thomassen, Elisabeth ^a   Cao, Manqiu ^b   Dreier, Torsten ^c   Fischer, David ^d   Höß, Adolf ^a   Inge, Landon ^b   Knappik, Achim ^a   Marget, Matthias ^e   Pack, Peter ^a   Meng, Xian Qin ^b   Schier, Robert ^a   Söhlemann, Peter ^a   Winter, Jill ^b   Wölle, Joachim ^a   Kretzschmar, Titus ^a  

^a MORPHOSYS AG   (Germany)

^b NOVARTIS PHARMA AG   (Switzerland)

^c MICROMET AG   (Germany)

^d PFIZER INC   (United States)

^e UNIVERSITY OF KIEL   (Germany)

Author keywords

Automation; Human antibodies; Phage display library; Whole cell panning

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN;

ANTIBODY DETECTION; ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; GENE LIBRARY; GENE SEQUENCE; GENETIC ENGINEERING; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN TARGETING;

ANIMALS; ANTIBODY AFFINITY; ANTIBODY FORMATION; ANTIGENS, NEOPLASM; AUTOMATION; BLOTTING, WESTERN; CELL ADHESION MOLECULES; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; FLOW CYTOMETRY; HL-60 CELLS; HLA-C ANTIGENS; HT29 CELLS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOHISTOCHEMISTRY; INTERCELLULAR ADHESION MOLECULE-1; MACROPHAGE-1 ANTIGEN; PEPTIDE LIBRARY; PRECIPITIN TESTS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECOMBINANT PROTEINS; SURFACE PLASMON RESONANCE;

ESCHERICHIA COLI;

EID: 0035427605     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(01)00398-2     Document Type: Article

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