Stability of acetal and non acetal-type analogs of artemisinin in simulated stomach acid

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 9, 1998, Pages 1003-1006

  Jung, Mankil ^a   Lee, Seokjoon ^a  

^a Yonsei University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMISININ;

ARTICLE; CHEMICAL BOND; DRUG BIOAVAILABILITY; DRUG CONFORMATION; DRUG STABILITY; MOLECULAR STABILITY; STOMACH ACID SECRETION; STRUCTURE ANALYSIS;

ACETALS; ANTIMALARIALS; ARTEMISININS; DRUG DESIGN; DRUG STABILITY; GASTRIC ACID; HUMANS; HYDROLYSIS; KINETICS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032080612     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00160-7     Document Type: Article

References (10)

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9. r = 4.43 min.) for system 2.
10. 10. Jung, M.; Lee, S., Heterocycles, 1997, 45, 1055.