Orally active antimalarial 3-substituted trioxanes: New synthetic methodology and biological evaluation

Journal of Medicinal Chemistry

Volumn 41, Issue 6, 1998, Pages 940-951

  Posner, Gary H ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 TRIOXANE DERIVATIVE; ANTIMALARIAL AGENT; IRON DERIVATIVE;

ANIMAL CELL; ANTIMALARIAL ACTIVITY; ARTICLE; DRUG DEGRADATION; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; ANIMALS; ANTIMALARIALS; BICYCLO COMPOUNDS, HETEROCYCLIC; DRUG EVALUATION, PRECLINICAL; MICE; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032510451     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970686e     Document Type: Article

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