Ferryl-oxo heme intermediate in the antimalarial mode of action of artemisinin

FEBS Letters

Volumn 474, Issue 2-3, 2000, Pages 238-241

  Kapetanaki, Sofia ^a   Varotsis, Constantinos ^a  

^a UNIVERSITY OF CRETE   (Greece)

Author keywords

Antimalarial; Ferryl oxo; Fourier transform infrared; Resonance Raman

Indexed keywords

ANTIMALARIAL AGENT; ARTEMISININ; CYTOCHROME P450; DIMER; ENDOPEROXIDE; HEME; HEMIN; IRON; OXYGEN; OXYGEN 18; TRIOXANE ALCOHOL; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG MECHANISM; FOURIER TRANSFORMATION; INFRARED SPECTROPHOTOMETRY; PRIORITY JOURNAL; RAMAN SPECTROMETRY; REACTION ANALYSIS;

ANTIMALARIALS; ARTEMISININS; DIMERIZATION; HEME; HEMIN; HETEROCYCLIC COMPOUNDS, 3-RING; IRON; KINETICS; OXIDATION-REDUCTION; OXYGEN; OXYGEN ISOTOPES; SESQUITERPENES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SPECTRUM ANALYSIS, RAMAN; VIBRATION;

EID: 0034595893     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(00)01592-1     Document Type: Article

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