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Journal of Medicinal Chemistry

Volumn 44, Issue 19, 2001, Pages 3054-3058

Antimalarial simplified 3-aryltrioxanes: Synthesis and preclinical efficacy/toxicity testing in rodents

(6) Posner, G H a Heung Bae Jeon, a Parker, M H a Krasavin, M a Paik, I H a Shapiro, T A b

a JOHNS HOPKINS UNIVERSITY (United States)

b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ARTELINIC ACID; CARBOXYLIC ACID DERIVATIVE; OXYGEN; PEROXIDE; TRIOXANE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIMALARIAL ACTIVITY; ARTICLE; BLOOD TOXICITY; CONTROLLED STUDY; DIASTEREOISOMER; DRUG EFFICACY; DRUG SAFETY; DRUG STABILITY; DRUG SYNTHESIS; HISTOPATHOLOGY; HYDROLYSIS; HYDROPHILICITY; LIVER TOXICITY; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; THERMOSTABILITY; WEIGHT REDUCTION;

ANIMALS; ANTIMALARIALS; BENZOIC ACIDS; BICYCLO COMPOUNDS, HETEROCYCLIC; DRUG EVALUATION, PRECLINICAL; DRUG STORAGE; HETEROCYCLIC COMPOUNDS, 3-RING; MALE; MICE; PLASMODIUM BERGHEI; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035855920 PISSN: 00222623 EISSN: None Source Type: Journal
DOI: 10.1021/jm0102396 Document Type: Article

Times cited : (65)

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