Evidence for the importance of high-valent Fe=O and of a diketone in the molecular mechanism of action of antimalarial trioxane analogs of artemisinin

Journal of the American Chemical Society

Volumn 118, Issue 14, 1996, Pages 3537-3538

  Posner, Gary H ^a   Park, Sheldon B ^a   González, Lluïsa ^a   Wang, Dasong ^a   Cumming, Jared N ^a,d   Klinedinst, Donna ^b   Shapiro, Theresa A ^b   Bachi, Mario D ^c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^d AMERICAN CHEMICAL SOCIETY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ARTEETHER; ARTEMISININ; ARTEMISININ DERIVATIVE; CHLOROQUINE;

ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG RESISTANCE; DRUG SYNTHESIS; PLASMODIUM FALCIPARUM;

EID: 0029995163     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja954131p     Document Type: Article

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