Trioxane dimers have potent antimalarial, antiproliferative and antitumor activities in vitro

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 7, 1997, Pages 1257-1265

  Posner, Gary H ^a   Ploypradith, Poonsakdi ^a   Hapangama, Whitney ^a   Wang, Dasong ^a   Cumming, Jared N ^a   Dolan, Patrick ^b   Kensler, Thomas W ^b   Klinedinst, Donna ^c   Shapiro, Theresa A ^c   Zheng, Qun Yi ^d   Murray, Christopher K ^d   Pilkington, Lynn G ^d   Jayasinghe, Lalith R ^d   Bray, Jeff F ^d   Daughenbaugh, Randy ^d  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Hauser Chemical Research Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 TRIOXANE DERIVATIVE; ANTIMALARIAL AGENT; ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; CALCITRIOL; CYTOTOXIC AGENT; DIHYDROARTEMISININ; DIHYDROARTEMISININ DERIVATIVE; POLYCYCLIC HYDROCARBON;

ANIMAL CELL; ANTIMALARIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CULTURE; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLASMODIUM FALCIPARUM; TUMOR CELL;

ANTIMALARIALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; DIMERIZATION; DRUG SCREENING ASSAYS, ANTITUMOR; HETEROCYCLIC COMPOUNDS; HUMANS; TUMOR CELLS, CULTURED;

ANIMALIA; PLASMODIUM FALCIPARUM;

EID: 0030796210     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)00079-5     Document Type: Article

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