Synthesis, stability, and antimalarial activity of new hydrolytically stable and water-soluble (+)-deoxoartelinic acid

Journal of Medicinal Chemistry

Volumn 45, Issue 22, 2002, Pages 4940-4944

  Jung, Mankil ^a   Lee, Kyunghoon ^a   Kendrick, Howard ^b   Robinson, Brian L ^c   Croft, Simon L ^b  

^a Yonsei University   (South Korea)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c NORTHWICK PARK INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ARTEETHER; ARTELINIC ACID; ARTEMISINIC ACID; ARTEMISININ; CHLOROQUINE; DEOXOARTELINIC ACID; DEOXOARTEMISININ; SULFUR DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYCLIZATION; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG POTENCY; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; FEMALE; MOUSE; NONHUMAN; PLASMODIUM CHABAUDI; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; CHLOROQUINE; DRUG RESISTANCE; HETEROCYCLIC COMPOUNDS, 3-RING; HYDROLYSIS; MALARIA; MICE; PLASMODIUM; SOLUBILITY; STEREOISOMERISM;

EID: 0037168048     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020244p     Document Type: Article

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