-
1
-
-
0028838971
-
Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signalling
-
T. Hunter Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signalling Cell 80 1995 225 236
-
(1995)
Cell
, vol.80
, pp. 225-236
-
-
Hunter, T.1
-
2
-
-
1842763560
-
Pinning down cell signaling, cancer and Alzheimer's disease
-
K.P. Lu Pinning down cell signaling, cancer and Alzheimer's disease Trends Biol. Sci. 29 2004 200 209
-
(2004)
Trends Biol. Sci.
, vol.29
, pp. 200-209
-
-
Lu, K.P.1
-
3
-
-
0036535975
-
Pinning down proline-directed phosphorylation signaling
-
K.P. Lu, Y.C. Liou, and X.Z. Zhou Pinning down proline-directed phosphorylation signaling Trends Cell Biol. 12 2002 164 172
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 164-172
-
-
Lu, K.P.1
Liou, Y.C.2
Zhou, X.Z.3
-
4
-
-
0033540064
-
Alzheimer's disease. The tangled tale of tau
-
E. Mandelkow Alzheimer's disease. The tangled tale of tau Nature 402 1999 588 589
-
(1999)
Nature
, vol.402
, pp. 588-589
-
-
Mandelkow, E.1
-
5
-
-
0003374626
-
Tau protein pathology in neurodegenerative diseases
-
M.G. Spillantini, and M. Goedert Tau protein pathology in neurodegenerative diseases Trends Neurosci. 21 1998 428 433
-
(1998)
Trends Neurosci.
, vol.21
, pp. 428-433
-
-
Spillantini, M.G.1
Goedert, M.2
-
7
-
-
0034971707
-
Missense and splice site mutations in tau associated with FTDP-17: Multiple pathogenic mechanisms
-
M. Hutton Missense and splice site mutations in tau associated with FTDP-17: multiple pathogenic mechanisms Neurology 56 2001 S21 S25
-
(2001)
Neurology
, vol.56
-
-
Hutton, M.1
-
8
-
-
0032786370
-
Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein
-
K. Spittaels, C. Van den Haute, J. Van Dorpe, K. Bruynseels, K. Vandezande, I. Laenen, H. Geerts, M. Mercken, R. Sciot, A. Van Lommel, R. Loos, and F. Van Leuven Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein Am. J. Pathol. 155 1999 2153 2165
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 2153-2165
-
-
Spittaels, K.1
Van Den Haute, C.2
Van Dorpe, J.3
Bruynseels, K.4
Vandezande, K.5
Laenen, I.6
Geerts, H.7
Mercken, M.8
Sciot, R.9
Van Lommel, A.10
Loos, R.11
Van Leuven, F.12
-
9
-
-
0034426011
-
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
-
J. Lewis, E. McGowan, J. Rockwood, H. Melrose, P. Nacharaju, M. Van Slegtenhorst, K. Gwinn-Hardy, M. Paul Murphy, M. Baker, X. Yu, K. Duff, J. Hardy, A. Corral, W.L. Lin, S.H. Yen, D.W. Dickson, P. Davies, and M. Hutton Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein Nat. Genet. 25 2000 402 405
-
(2000)
Nat. Genet.
, vol.25
, pp. 402-405
-
-
Lewis, J.1
McGowan, E.2
Rockwood, J.3
Melrose, H.4
Nacharaju, P.5
Van Slegtenhorst, M.6
Gwinn-Hardy, K.7
Paul Murphy, M.8
Baker, M.9
Yu, X.10
Duff, K.11
Hardy, J.12
Corral, A.13
Lin, W.L.14
Yen, S.H.15
Dickson, D.W.16
Davies, P.17
Hutton, M.18
-
10
-
-
0033230886
-
Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform
-
T. Ishihara, M. Hong, B. Zhang, Y. Nakagawa, M.K. Lee, J.Q. Trojanowski, and V.M. Lee Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform Neuron 24 1999 751 762
-
(1999)
Neuron
, vol.24
, pp. 751-762
-
-
Ishihara, T.1
Hong, M.2
Zhang, B.3
Nakagawa, Y.4
Lee, M.K.5
Trojanowski, J.Q.6
Lee, V.M.7
-
11
-
-
0035808361
-
Tau filament formation in transgenic mice expressing P301L tau
-
J. Gotz, F. Chen, R. Barmettler, and R.M. Nitsch Tau filament formation in transgenic mice expressing P301L tau J. Biol. Chem. 276 2001 529 534
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 529-534
-
-
Gotz, J.1
Chen, F.2
Barmettler, R.3
Nitsch, R.M.4
-
12
-
-
0028965635
-
Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform
-
J. Gotz, A. Probst, M.G. Spillantini, T. Schafer, R. Jakes, K. Burki, and M. Goedert Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform EMBO J. 14 1995 1304 1313
-
(1995)
EMBO J.
, vol.14
, pp. 1304-1313
-
-
Gotz, J.1
Probst, A.2
Spillantini, M.G.3
Schafer, T.4
Jakes, R.5
Burki, K.6
Goedert, M.7
-
13
-
-
0345580607
-
Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease
-
J.P. Brion, G. Tremp, and J.N. Octave Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease (see comments) Am. J. Pathol. 154 1999 255 270
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 255-270
-
-
Brion, J.P.1
Tremp, G.2
Octave, J.N.3
-
14
-
-
0036138044
-
Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau
-
K. Tanemura, M. Murayama, T. Akagi, T. Hashikawa, T. Tominaga, M. Ichikawa, H. Yamaguchi, and A. Takashima Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau J. Neurosci. 22 2002 133 141
-
(2002)
J. Neurosci.
, vol.22
, pp. 133-141
-
-
Tanemura, K.1
Murayama, M.2
Akagi, T.3
Hashikawa, T.4
Tominaga, T.5
Ichikawa, M.6
Yamaguchi, H.7
Takashima, A.8
-
15
-
-
0028981873
-
Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells
-
B.R. Sperber, S. Leight, M. Goedert, and V.M. Lee Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells Neurosci. Lett. 197 1995 149 153
-
(1995)
Neurosci. Lett.
, vol.197
, pp. 149-153
-
-
Sperber, B.R.1
Leight, S.2
Goedert, M.3
Lee, V.M.4
-
16
-
-
0030461275
-
Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A
-
E. Sontag, V. Nunbhakdi-Craig, G. Lee, G.S. Bloom, and M.C. Mumby Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A Neuron 17 1996 1201 1207
-
(1996)
Neuron
, vol.17
, pp. 1201-1207
-
-
Sontag, E.1
Nunbhakdi-Craig, V.2
Lee, G.3
Bloom, G.S.4
Mumby, M.C.5
-
17
-
-
0034067992
-
Phosphorylation sites on tau identified by nanoelectrospray mass spectrometry: Differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and P38, and glycogen synthase kinase-3beta
-
C.H. Reynolds, J.C. Betts, W.P. Blackstock, A.R. Nebreda, and B.H. Anderton Phosphorylation sites on tau identified by nanoelectrospray mass spectrometry: differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and P38, and glycogen synthase kinase-3beta J. Neurochem. 74 2000 1587 1595
-
(2000)
J. Neurochem.
, vol.74
, pp. 1587-1595
-
-
Reynolds, C.H.1
Betts, J.C.2
Blackstock, W.P.3
Nebreda, A.R.4
Anderton, B.H.5
-
18
-
-
0033957692
-
PD98059 prevents neurite degeneration induced by fibrillar beta-amyloid in mature hippocampal neurons
-
M. Rapoport, and A. Ferreira PD98059 prevents neurite degeneration induced by fibrillar beta-amyloid in mature hippocampal neurons J. Neurochem. 74 2000 125 133
-
(2000)
J. Neurochem.
, vol.74
, pp. 125-133
-
-
Rapoport, M.1
Ferreira, A.2
-
19
-
-
0032502829
-
Characterization of tau phosphorylation in glycogen synthase kinase-3beta and cyclin dependent kinase-5 activator (p23) transfected cells
-
G. Michel, M. Mercken, M. Murayama, K. Noguchi, K. Ishiguro, K. Imahori, and A. Takashima Characterization of tau phosphorylation in glycogen synthase kinase-3beta and cyclin dependent kinase-5 activator (p23) transfected cells Biochim. Biophys. Acta 1380 1998 177 182
-
(1998)
Biochim. Biophys. Acta
, vol.1380
, pp. 177-182
-
-
Michel, G.1
Mercken, M.2
Murayama, M.3
Noguchi, K.4
Ishiguro, K.5
Imahori, K.6
Takashima, A.7
-
20
-
-
0035851175
-
Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice
-
S. Kins, A. Crameri, D.R. Evans, B.A. Hemmings, R.M. Nitsch, and J. Gotz Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice J. Biol. Chem. 276 2001 38193 38200
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38193-38200
-
-
Kins, S.1
Crameri, A.2
Evans, D.R.3
Hemmings, B.A.4
Nitsch, R.M.5
Gotz, J.6
-
21
-
-
0034088846
-
Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer's disease
-
C.X. Gong, T. Lidsky, J. Wegiel, L. Zuck, I. Grundke-Iqbal, and K. Iqbal Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer's disease J. Biol. Chem. 275 2000 5535 5544
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 5535-5544
-
-
Gong, C.X.1
Lidsky, T.2
Wegiel, J.3
Zuck, L.4
Grundke-Iqbal, I.5
Iqbal, K.6
-
22
-
-
85062139768
-
Tau phosphorylation in brain slices: Pharmacological evidence for convergent effects of protein phosphatases on tau and mitogen-activated protein kinase
-
T.D. Garver, G.A. Oyler, K.A. Harris, R. Polavarapu, Z. Damuni, R.A. Lehman, and M.L. Billingsley Tau phosphorylation in brain slices: pharmacological evidence for convergent effects of protein phosphatases on tau and mitogen-activated protein kinase Mol. Pharmacol. 47 1995 745 756
-
(1995)
Mol. Pharmacol.
, vol.47
, pp. 745-756
-
-
Garver, T.D.1
Oyler, G.A.2
Harris, K.A.3
Polavarapu, R.4
Damuni, Z.5
Lehman, R.A.6
Billingsley, M.L.7
-
23
-
-
0028937631
-
Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262
-
G. Drewes, B. Trinczek, S. Illenberger, J. Biernat, G. Schmitt-Ulms, H.E. Meyer, E.M. Mandelkow, and E. Mandelkow Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262 J. Biol. Chem. 270 1995 7679 7688
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7679-7688
-
-
Drewes, G.1
Trinczek, B.2
Illenberger, S.3
Biernat, J.4
Schmitt-Ulms, G.5
Meyer, H.E.6
Mandelkow, E.M.7
Mandelkow, E.8
-
24
-
-
12944268979
-
Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5
-
M.K. Ahlijanian, N.X. Barrezueta, R.D. Williams, A. Jakowski, K.P. Kowsz, S. McCarthy, T. Coskran, A. Carlo, P.A. Seymour, J.E. Burkhardt, R.B. Nelson, and J.D. McNeish Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5 Proc. Natl. Acad. Sci. U. S. A. 97 2000 2910 2915
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 2910-2915
-
-
Ahlijanian, M.K.1
Barrezueta, N.X.2
Williams, R.D.3
Jakowski, A.4
Kowsz, K.P.5
McCarthy, S.6
Coskran, T.7
Carlo, A.8
Seymour, P.A.9
Burkhardt, J.E.10
Nelson, R.B.11
McNeish, J.D.12
-
25
-
-
0033788787
-
Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations
-
M. Goedert, S. Satumtira, R. Jakes, M.J. Smith, C. Kamibayashi, C.L. White III, and E. Sontag Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations J. Neurochem. 75 2000 2155 2162
-
(2000)
J. Neurochem.
, vol.75
, pp. 2155-2162
-
-
Goedert, M.1
Satumtira, S.2
Jakes, R.3
Smith, M.J.4
Kamibayashi, C.5
White III, C.L.6
Sontag, E.7
-
26
-
-
0033544963
-
The microtubule binding of Tau and high molecular weight Tau in apoptotic PC12 cells is impaired because of altered phosphorylation
-
P.K. Davis, and G.V. Johnson The microtubule binding of Tau and high molecular weight Tau in apoptotic PC12 cells is impaired because of altered phosphorylation J. Biol. Chem. 274 1999 35686 35692
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 35686-35692
-
-
Davis, P.K.1
Johnson, G.V.2
-
27
-
-
0026551711
-
The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region
-
J. Biernat, E.M. Mandelkow, C. Schroter, B. Lichtenberg-Kraag, B. Steiner, B. Berling, H. Meyer, M. Mercken, A. Vandermeeren, and M. Goedert The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region EMBO J. 11 1992 1593 1597
-
(1992)
EMBO J.
, vol.11
, pp. 1593-1597
-
-
Biernat, J.1
Mandelkow, E.M.2
Schroter, C.3
Lichtenberg-Kraag, B.4
Steiner, B.5
Berling, B.6
Meyer, H.7
Mercken, M.8
Vandermeeren, A.9
Goedert, M.10
-
28
-
-
0034282067
-
Conformational change as one of the earliest alterations of tau in Alzheimer's disease
-
C.L. Weaver, M. Espinoza, Y. Kress, and P. Davies Conformational change as one of the earliest alterations of tau in Alzheimer's disease Neurobiol. Aging 21 2000 719 727
-
(2000)
Neurobiol. Aging
, vol.21
, pp. 719-727
-
-
Weaver, C.L.1
Espinoza, M.2
Kress, Y.3
Davies, P.4
-
29
-
-
0029916122
-
A human peptidyl-prolyl isomerase essential for regulation of mitosis
-
K.P. Lu, S.D. Hanes, and T. Hunter A human peptidyl-prolyl isomerase essential for regulation of mitosis Nature 380 1996 544 547
-
(1996)
Nature
, vol.380
, pp. 544-547
-
-
Lu, K.P.1
Hanes, S.D.2
Hunter, T.3
-
30
-
-
0343177223
-
A structural basis for substrate specificities of protein Ser/Thr-kinases: Primary sequence preference of casein kinase 1 and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1
-
Z. Songyang, K.P. Lu, Y.T. Kwon, L.-H. Tsai, O. Filhol, C. Cochet, D.A. Brickey, T.R. Soderling, C. Bartleson, D.J. Graves, A.J. DeMaggio, M.F. Hoekstra, J. Blenis, T. Hunter, and L.C. Cantley A structural basis for substrate specificities of protein Ser/Thr-kinases: Primary sequence preference of casein kinase 1 and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1 Mol. Cell. Biol. 16 1996 6486 6493
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 6486-6493
-
-
Songyang, Z.1
Lu, K.P.2
Kwon, Y.T.3
Tsai, L.-H.4
Filhol, O.5
Cochet, C.6
Brickey, D.A.7
Soderling, T.R.8
Bartleson, C.9
Graves, D.J.10
Demaggio, A.J.11
Hoekstra, M.F.12
Blenis, J.13
Hunter, T.14
Cantley, L.C.15
-
31
-
-
0031470652
-
The structural basis for 14-3-3:phosphopeptide binding specificity
-
M.B. Yaffe, K. Rittinger, S. Volinia, P.R. Caron, A. Aitken, H. Leffers, S.J. Gamblin, S.J. Smerdon, and L.C. Cantley The structural basis for 14-3-3:phosphopeptide binding specificity Cell 91 1997 961 971
-
(1997)
Cell
, vol.91
, pp. 961-971
-
-
Yaffe, M.B.1
Rittinger, K.2
Volinia, S.3
Caron, P.R.4
Aitken, A.5
Leffers, H.6
Gamblin, S.J.7
Smerdon, S.J.8
Cantley, L.C.9
-
32
-
-
0008233581
-
Structural and functional analysis of the mitotic peptidyl-prolyl isomerase Pin1 suggests that substrate recognition is phosphorylation dependent
-
R. Ranganathan, K.P. Lu, T. Hunter, and J.P. Noel Structural and functional analysis of the mitotic peptidyl-prolyl isomerase Pin1 suggests that substrate recognition is phosphorylation dependent Cell 89 1997 875 886
-
(1997)
Cell
, vol.89
, pp. 875-886
-
-
Ranganathan, R.1
Lu, K.P.2
Hunter, T.3
Noel, J.P.4
-
33
-
-
0036315162
-
Pin1 is an E2F target gene essential for the Neu/Ras-induced transformation of mammary epithelial cells
-
A. Ryo, Y.C. Liou, G. Wulf, N. Nakamura, S.W. Lee, and K.P. Lu Pin1 is an E2F target gene essential for the Neu/Ras-induced transformation of mammary epithelial cells Mol. Cell. Biol. 22 2002 5281 5295
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5281-5295
-
-
Ryo, A.1
Liou, Y.C.2
Wulf, G.3
Nakamura, N.4
Lee, S.W.5
Lu, K.P.6
-
34
-
-
0033600242
-
The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein
-
P.J. Lu, G. Wulf, X.Z. Zhou, P. Davies, and K.P. Lu The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein Nature 399 1999 784 788
-
(1999)
Nature
, vol.399
, pp. 784-788
-
-
Lu, P.J.1
Wulf, G.2
Zhou, X.Z.3
Davies, P.4
Lu, K.P.5
-
35
-
-
0033638180
-
Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins
-
X.Z. Zhou, O. Kops, A. Werner, P.J. Lu, M. Shen, G. Stoller, G. Küllertz, M. Stark, G. Fischer, and K.P. Lu Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins Mol. Cell 6 2000 873 883
-
(2000)
Mol. Cell
, vol.6
, pp. 873-883
-
-
Zhou, X.Z.1
Kops, O.2
Werner, A.3
Lu, P.J.4
Shen, M.5
Stoller, G.6
Küllertz, G.7
Stark, M.8
Fischer, G.9
Lu, K.P.10
-
36
-
-
0043069764
-
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration
-
Y.-C. Liou, A. Sun, A. Ryo, X.Z. Zhou, Z.-X. Yu, H.-K. Huang, R. Bronson, G. Bing, X. Li, T. Hunter, and K.P. Lu Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration Nature 424 2003 556 561
-
(2003)
Nature
, vol.424
, pp. 556-561
-
-
Liou, Y.-C.1
Sun, A.2
Ryo, A.3
Zhou, X.Z.4
Yu, Z.-X.5
Huang, H.-K.6
Bronson, R.7
Bing, G.8
Li, X.9
Hunter, T.10
Lu, K.P.11
-
38
-
-
0021338217
-
Phosphorylation affects the ability of tau protein to promote microtubule assembly
-
G. Lindwall, and R.D. Cole Phosphorylation affects the ability of tau protein to promote microtubule assembly J. Biol. Chem. 259 1984 5301 5305
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 5301-5305
-
-
Lindwall, G.1
Cole, R.D.2
-
39
-
-
0022395021
-
Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors
-
D.G. Drubin, S.C. Feinstein, E.M. Shooter, and M.W. Kirschner Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors J. Cell Biol. 101 1985 1799 1807
-
(1985)
J. Cell Biol.
, vol.101
, pp. 1799-1807
-
-
Drubin, D.G.1
Feinstein, S.C.2
Shooter, E.M.3
Kirschner, M.W.4
-
40
-
-
0035067021
-
Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice
-
H.N. Dawson, A. Ferreira, M.V. Eyster, N. Ghoshal, L.I. Binder, and M.P. Vitek Inhibition of neuronal maturation in primary hippocampal neurons from tau deficient mice J. Cell. Sci. 114 2001 1179 1187
-
(2001)
J. Cell. Sci.
, vol.114
, pp. 1179-1187
-
-
Dawson, H.N.1
Ferreira, A.2
Eyster, M.V.3
Ghoshal, N.4
Binder, L.I.5
Vitek, M.P.6
-
41
-
-
0034605045
-
Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes
-
Y. Takei, J. Teng, A. Harada, and N. Hirokawa Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes J. Cell Biol. 150 2000 989 1000
-
(2000)
J. Cell Biol.
, vol.150
, pp. 989-1000
-
-
Takei, Y.1
Teng, J.2
Harada, A.3
Hirokawa, N.4
-
42
-
-
0029999787
-
Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules
-
A.C. Alonso, I. Grundke-Iqbal, and K. Iqbal Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules Nat. Med. 2 1996 783 787
-
(1996)
Nat. Med.
, vol.2
, pp. 783-787
-
-
Alonso, A.C.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
43
-
-
0033070197
-
High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands
-
P. Rizzu, J.C. Van Swieten, M. Joosse, M. Hasegawa, M. Stevens, A. Tibben, M.F. Niermeijer, M. Hillebrand, R. Ravid, B.A. Oostra, M. Goedert, C.M. van Duijn, and P. Heutink High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands Am. J. Hum. Genet. 64 1999 414 421
-
(1999)
Am. J. Hum. Genet.
, vol.64
, pp. 414-421
-
-
Rizzu, P.1
Van Swieten, J.C.2
Joosse, M.3
Hasegawa, M.4
Stevens, M.5
Tibben, A.6
Niermeijer, M.F.7
Hillebrand, M.8
Ravid, R.9
Oostra, B.A.10
Goedert, M.11
Van Duijn, C.M.12
Heutink, P.13
-
44
-
-
0032543684
-
Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17
-
M. Hutton, C.L. Lendon, P. Rizzu, M. Baker, S. Froelich, H. Houlden, S. Pickering-Brown, S. Chakraverty, A. Isaacs, A. Grover, J. Hackett, J. Adamson, S. Lincoln, D. Dickson, P. Davies, R.C. Petersen, M. Stevens, E. de Graaff, E. Wauters, J. van Baren, M. Hillebrand, M. Joosse, J.M. Kwon, P. Nowotny, and P. Heutink Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17 Nature 393 1998 702 705
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
Lendon, C.L.2
Rizzu, P.3
Baker, M.4
Froelich, S.5
Houlden, H.6
Pickering-Brown, S.7
Chakraverty, S.8
Isaacs, A.9
Grover, A.10
Hackett, J.11
Adamson, J.12
Lincoln, S.13
Dickson, D.14
Davies, P.15
Petersen, R.C.16
Stevens, M.17
De Graaff, E.18
Wauters, E.19
Van Baren, J.20
Hillebrand, M.21
Joosse, M.22
Kwon, J.M.23
Nowotny, P.24
Heutink, P.25
more..
-
45
-
-
0032484089
-
Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17
-
M. Hong, V. Zhukareva, V. Vogelsberg-Ragaglia, Z. Wszolek, L. Reed, B.I. Miller, D.H. Geschwind, T.D. Bird, D. McKeel, A. Goate, J.C. Morris, K.C. Wilhelmsen, G.D. Schellenberg, J.Q. Trojanowski, and V.M.Y. Lee Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17 Science 282 1998 1914 1917
-
(1998)
Science
, vol.282
, pp. 1914-1917
-
-
Hong, M.1
Zhukareva, V.2
Vogelsberg-Ragaglia, V.3
Wszolek, Z.4
Reed, L.5
Miller, B.I.6
Geschwind, D.H.7
Bird, T.D.8
McKeel, D.9
Goate, A.10
Morris, J.C.11
Wilhelmsen, K.C.12
Schellenberg, G.D.13
Trojanowski, J.Q.14
Lee, V.M.Y.15
-
46
-
-
0033596946
-
Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments
-
A. Schneider, J. Biernat, M. von Bergen, E. Mandelkow, and E.M. Mandelkow Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments Biochemistry 38 1999 3549 3558
-
(1999)
Biochemistry
, vol.38
, pp. 3549-3558
-
-
Schneider, A.1
Biernat, J.2
Von Bergen, M.3
Mandelkow, E.4
Mandelkow, E.M.5
-
47
-
-
0033963038
-
Conformation of paired helical filaments blocks dephosphorylation of epitopes shared with fetal tau except Ser199/202 and Ser202/Thr205
-
W. Gordon-Krajcer, L. Yang, and H. Ksiezak-Reding Conformation of paired helical filaments blocks dephosphorylation of epitopes shared with fetal tau except Ser199/202 and Ser202/Thr205 Brain Res. 856 2000 163 175
-
(2000)
Brain Res.
, vol.856
, pp. 163-175
-
-
Gordon-Krajcer, W.1
Yang, L.2
Ksiezak-Reding, H.3
-
48
-
-
0026787130
-
Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain
-
M. Hasegawa, M. Morishima-Kawashima, K. Takio, M. Suzuki, K. Titani, and Y. Ihara Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain J. Biol. Chem. 267 1992 17047 17054
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17047-17054
-
-
Hasegawa, M.1
Morishima-Kawashima, M.2
Takio, K.3
Suzuki, M.4
Titani, K.5
Ihara, Y.6
-
49
-
-
0034733918
-
Detection of tau phosphorylated at threonine 231 in cerebrospinal fluid of Alzheimer's disease patients
-
R. Kohnken, K. Buerger, R. Zinkowski, C. Miller, D. Kerkman, J. DeBernardis, J. Shen, H.J. Moller, P. Davies, and H. Hampel Detection of tau phosphorylated at threonine 231 in cerebrospinal fluid of Alzheimer's disease patients Neurosci. Lett. 287 2000 187 190
-
(2000)
Neurosci. Lett.
, vol.287
, pp. 187-190
-
-
Kohnken, R.1
Buerger, K.2
Zinkowski, R.3
Miller, C.4
Kerkman, D.5
Debernardis, J.6
Shen, J.7
Moller, H.J.8
Davies, P.9
Hampel, H.10
-
50
-
-
1542358895
-
PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila
-
I. Nishimura, Y. Yang, and B. Lu PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila Cell 116 2004 671 682
-
(2004)
Cell
, vol.116
, pp. 671-682
-
-
Nishimura, I.1
Yang, Y.2
Lu, B.3
-
51
-
-
0041827252
-
The role of PAR-1 in regulating the polarised microtubule cytoskeleton in the Drosophila follicular epithelium
-
H. Doerflinger, R. Benton, J.M. Shulman, and D. St Johnston The role of PAR-1 in regulating the polarised microtubule cytoskeleton in the Drosophila follicular epithelium Development 130 2003 3965 3975
-
(2003)
Development
, vol.130
, pp. 3965-3975
-
-
Doerflinger, H.1
Benton, R.2
Shulman, J.M.3
St Johnston, D.4
-
52
-
-
0032521599
-
Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase a at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation
-
Q. Zheng-Fischhofer, J. Biernat, E.M. Mandelkow, S. Illenberger, R. Godemann, and E. Mandelkow Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical- filament-like conformation Eur. J. Biochem. 252 1998 542 552
-
(1998)
Eur. J. Biochem.
, vol.252
, pp. 542-552
-
-
Zheng-Fischhofer, Q.1
Biernat, J.2
Mandelkow, E.M.3
Illenberger, S.4
Godemann, R.5
Mandelkow, E.6
-
53
-
-
0035933621
-
Involvement of cyclin dependent kinase5 activator p25 on tau phosphorylation in mouse brain
-
A. Takashima, M. Murayama, K. Yasutake, H. Takahashi, M. Yokoyama, and K. Ishiguro Involvement of cyclin dependent kinase5 activator p25 on tau phosphorylation in mouse brain Neurosci. Lett. 306 2001 37 40
-
(2001)
Neurosci. Lett.
, vol.306
, pp. 37-40
-
-
Takashima, A.1
Murayama, M.2
Yasutake, K.3
Takahashi, H.4
Yokoyama, M.5
Ishiguro, K.6
-
54
-
-
0027255817
-
Glycogen synthase kinase 3 beta is identical to tau protein kinase I generating several epitopes of paired helical filaments
-
K. Ishiguro, A. Shiratsuchi, S. Sato, A. Omori, M. Arioka, S. Kobayashi, T. Uchida, and K. Imahori Glycogen synthase kinase 3 beta is identical to tau protein kinase I generating several epitopes of paired helical filaments FEBS Lett. 325 1993 167 172
-
(1993)
FEBS Lett.
, vol.325
, pp. 167-172
-
-
Ishiguro, K.1
Shiratsuchi, A.2
Sato, S.3
Omori, A.4
Arioka, M.5
Kobayashi, S.6
Uchida, T.7
Imahori, K.8
-
55
-
-
0032951956
-
Hierarchical phosphorylation of recombinant tau by the paired-helical filament-associated protein kinase is dependent on cyclic AMP-dependent protein kinase
-
G.A. Jicha, A. O'Donnell, C. Weaver, R. Angeletti, and P. Davies Hierarchical phosphorylation of recombinant tau by the paired-helical filament-associated protein kinase is dependent on cyclic AMP-dependent protein kinase J. Neurochem. 72 1999 214 224
-
(1999)
J. Neurochem.
, vol.72
, pp. 214-224
-
-
Jicha, G.A.1
O'Donnell, A.2
Weaver, C.3
Angeletti, R.4
Davies, P.5
-
56
-
-
0035863188
-
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
-
J.J. Lucas, F. Hernandez, P. Gomez-Ramos, M.A. Moran, R. Hen, and J. Avila Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice EMBO J. 20 2001 27 39
-
(2001)
EMBO J.
, vol.20
, pp. 27-39
-
-
Lucas, J.J.1
Hernandez, F.2
Gomez-Ramos, P.3
Moran, M.A.4
Hen, R.5
Avila, J.6
-
57
-
-
0038689162
-
Cdk5 is a key factor in tau aggregation and tangle formation in vivo
-
W. Noble, V. Olm, K. Takata, E. Casey, O. Mary, J. Meyerson, K. Gaynor, J. LaFrancois, L. Wang, T. Kondo, P. Davies, M. Burns, Veeranna, R. Nixon, D. Dickson, Y. Matsuoka, M. Ahlijanian, L.F. Lau, and K. Duff Cdk5 is a key factor in tau aggregation and tangle formation in vivo Neuron 38 2003 555 565
-
(2003)
Neuron
, vol.38
, pp. 555-565
-
-
Noble, W.1
Olm, V.2
Takata, K.3
Casey, E.4
Mary, O.5
Meyerson, J.6
Gaynor, K.7
Lafrancois, J.8
Wang, L.9
Kondo, T.10
Davies, P.11
Burns, M.12
Veeranna13
Nixon, R.14
Dickson, D.15
Matsuoka, Y.16
Ahlijanian, M.17
Lau, L.F.18
Duff, K.19
-
58
-
-
0038187674
-
GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides
-
C.J. Phiel, C.A. Wilson, V.M. Lee, and P.S. Klein GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides Nature 423 2003 435 439
-
(2003)
Nature
, vol.423
, pp. 435-439
-
-
Phiel, C.J.1
Wilson, C.A.2
Lee, V.M.3
Klein, P.S.4
-
59
-
-
0345405447
-
Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles
-
J.C. Cruz, H.C. Tseng, J.A. Goldman, H. Shih, and L.H. Tsai Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles Neuron 40 2003 471 483
-
(2003)
Neuron
, vol.40
, pp. 471-483
-
-
Cruz, J.C.1
Tseng, H.C.2
Goldman, J.A.3
Shih, H.4
Tsai, L.H.5
-
60
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
J. Kang, H.G. Lemaire, A. Unterbeck, J.M. Salbaum, C.L. Masters, K.H. Grzeschik, G. Multhaup, K. Beyreuther, and B. Muller-Hill The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor Nature 325 1987 733 736
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.G.2
Unterbeck, A.3
Salbaum, J.M.4
Masters, C.L.5
Grzeschik, K.H.6
Multhaup, G.7
Beyreuther, K.8
Muller-Hill, B.9
-
61
-
-
0029933153
-
The role of APP processing and trafficking pathways in the formation of amyloid beta-protein
-
D.J. Selkoe, T. Yamazaki, M. Citron, M.B. Podlisny, E.H. Koo, D.B. Teplow, and C. Haass The role of APP processing and trafficking pathways in the formation of amyloid beta-protein Ann. N.Y. Acad. Sci. 777 1996 57 64
-
(1996)
Ann. N.Y. Acad. Sci.
, vol.777
, pp. 57-64
-
-
Selkoe, D.J.1
Yamazaki, T.2
Citron, M.3
Podlisny, M.B.4
Koo, E.H.5
Teplow, D.B.6
Haass, C.7
-
62
-
-
0032211830
-
The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease
-
D.J. Selkoe The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease Trends Cell Biol. 8 1998 447 453
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 447-453
-
-
Selkoe, D.J.1
-
63
-
-
0023109592
-
Amyloid beta protein gene: CDNA, mRNA distribution, and genetic linkage near the Alzheimer locus
-
R.E. Tanzi, J.F. Gusella, P.C. Watkins, G.A. Bruns, P. St George-Hyslop, M.L. Van Keuren, D. Patterson, S. Pagan, D.M. Kurnit, and R.L. Neve Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus Science 235 1987 880 884
-
(1987)
Science
, vol.235
, pp. 880-884
-
-
Tanzi, R.E.1
Gusella, J.F.2
Watkins, P.C.3
Bruns, G.A.4
St George-Hyslop, P.5
Van Keuren, M.L.6
Patterson, D.7
Pagan, S.8
Kurnit, D.M.9
Neve, R.L.10
-
64
-
-
0033784099
-
Modeling Alzheimer's disease in transgenic mice: Effect of age and of presenilin1 on amyloid biochemistry and pathology in APP/London mice
-
I. Dewachter, J. van Dorpe, K. Spittaels, I. Tesseur, C. Van Den Haute, D. Moechars, and F. Van Leuven Modeling Alzheimer's disease in transgenic mice: effect of age and of presenilin1 on amyloid biochemistry and pathology in APP/London mice Exp. Gerontol. 35 2000 831 841
-
(2000)
Exp. Gerontol.
, vol.35
, pp. 831-841
-
-
Dewachter, I.1
Van Dorpe, J.2
Spittaels, K.3
Tesseur, I.4
Van Den Haute, C.5
Moechars, D.6
Van Leuven, F.7
-
65
-
-
9044239670
-
Familial and sporadic Alzheimer's disease: Neuropathology cannot exclude a final common pathway
-
C.F. Lippa, A.M. Saunders, T.W. Smith, J.M. Swearer, D.A. Drachman, B. Ghetti, L. Nee, D. Pulaski-Salo, D. Dickson, Y. Robitaille, C. Bergeron, B. Crain, M.D. Benson, M. Farlow, B.T. Hyman, S.P. George-Hyslop, A.D. Roses, and D.A. Pollen Familial and sporadic Alzheimer's disease: neuropathology cannot exclude a final common pathway Neurology 46 1996 406 412
-
(1996)
Neurology
, vol.46
, pp. 406-412
-
-
Lippa, C.F.1
Saunders, A.M.2
Smith, T.W.3
Swearer, J.M.4
Drachman, D.A.5
Ghetti, B.6
Nee, L.7
Pulaski-Salo, D.8
Dickson, D.9
Robitaille, Y.10
Bergeron, C.11
Crain, B.12
Benson, M.D.13
Farlow, M.14
Hyman, B.T.15
George-Hyslop, S.P.16
Roses, A.D.17
Pollen, D.A.18
-
66
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
D.R. Borchelt, T. Ratovitski, J. van Lare, M.K. Lee, V. Gonzales, N.A. Jenkins, N.G. Copeland, D.L. Price, and S.S. Sisodia Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins Neuron 19 1997 939 945
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
Lee, M.K.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Price, D.L.8
Sisodia, S.S.9
-
67
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo
-
D.R. Borchelt, G. Thinakaran, C.B. Eckman, M.K. Lee, F. Davenport, T. Ratovitsky, C.M. Prada, G. Kim, S. Seekins, D. Yager, H.H. Slunt, R. Wang, M. Seeger, A.I. Levey, S.E. Gandy, N.G. Copeland, N.A. Jenkins, D.L. Price, S.G. Younkin, and S.S. Sisodia Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo Neuron 17 1996 1005 1013
-
(1996)
Neuron
, vol.17
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Ratovitsky, T.6
Prada, C.M.7
Kim, G.8
Seekins, S.9
Yager, D.10
Slunt, H.H.11
Wang, R.12
Seeger, M.13
Levey, A.I.14
Gandy, S.E.15
Copeland, N.G.16
Jenkins, N.A.17
Price, D.L.18
Younkin, S.G.19
Sisodia, S.S.20
more..
-
68
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
L. Holcomb, M.N. Gordon, E. McGowan, X. Yu, S. Benkovic, P. Jantzen, K. Wright, I. Saad, R. Mueller, D. Morgan, S. Sanders, C. Zehr, K. O'Campo, J. Hardy, C.M. Prada, C. Eckman, S. Younkin, K. Hsiao, and K. Duff Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes Nat. Med. 4 1998 97 100
-
(1998)
Nat. Med.
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
Wright, K.7
Saad, I.8
Mueller, R.9
Morgan, D.10
Sanders, S.11
Zehr, C.12
O'Campo, K.13
Hardy, J.14
Prada, C.M.15
Eckman, C.16
Younkin, S.17
Hsiao, K.18
Duff, K.19
-
69
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
-
D. Games, D. Adams, R. Alessandrini, R. Barbour, P. Berthelette, C. Blackwell, T. Carr, J. Clemens, T. Donaldson, and F. Gillespie Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein Nature 373 1995 523 527
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
-
70
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
K. Hsiao, P. Chapman, S. Nilsen, C. Eckman, Y. Harigaya, S. Younkin, F. Yang, and G. Cole Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice Science 274 1996 99 102
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
71
-
-
0035943436
-
Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils
-
J. Gotz, F. Chen, J. van Dorpe, and R.M. Nitsch Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils Science 293 2001 1491 1495
-
(2001)
Science
, vol.293
, pp. 1491-1495
-
-
Gotz, J.1
Chen, F.2
Van Dorpe, J.3
Nitsch, R.M.4
-
72
-
-
17944382037
-
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
-
J. Lewis, D.W. Dickson, W.L. Lin, L. Chisholm, A. Corral, G. Jones, S.H. Yen, N. Sahara, L. Skipper, D. Yager, C. Eckman, J. Hardy, M. Hutton, and E. McGowan Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP Science 293 2001 1487 1491
-
(2001)
Science
, vol.293
, pp. 1487-1491
-
-
Lewis, J.1
Dickson, D.W.2
Lin, W.L.3
Chisholm, L.4
Corral, A.5
Jones, G.6
Yen, S.H.7
Sahara, N.8
Skipper, L.9
Yager, D.10
Eckman, C.11
Hardy, J.12
Hutton, M.13
McGowan, E.14
-
73
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction
-
S. Oddo, A. Caccamo, J.D. Shepherd, M.P. Murphy, T.E. Golde, R. Kayed, R. Metherate, M.P. Mattson, Y. Akbari, and F.M. LaFerla Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction Neuron 39 2003 409 421
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
Laferla, F.M.10
-
74
-
-
1242292029
-
Regulation of peptide bond cis/transisomerization by enzyme catalysis and its implication in physiological processes
-
G. Fischer, and T. Aumuller Regulation of peptide bond cis/transisomerization by enzyme catalysis and its implication in physiological processes Rev. Physiol. Biochem. Pharmacol. 148 2003 105 150
-
(2003)
Rev. Physiol. Biochem. Pharmacol.
, vol.148
, pp. 105-150
-
-
Fischer, G.1
Aumuller, T.2
-
75
-
-
0025035782
-
Substrate specificity for the human rotamerase FKBP: A view of FK506 and rapamycin as leucine-(twisted amide)-proline mimics
-
M.W. Albers, S.L. Schreiber, and C.T. Walsh Substrate specificity for the human rotamerase FKBP: a view of FK506 and rapamycin as leucine-(twisted amide)-proline mimics J. Org. Chem. 55 1990 4984 4986
-
(1990)
J. Org. Chem.
, vol.55
, pp. 4984-4986
-
-
Albers, M.W.1
Schreiber, S.L.2
Walsh, C.T.3
-
76
-
-
0025373627
-
Substrate specificities of the peptidyl prolyl cis-trans isomerase activities of cyclophilin and FK-506 binding protein: Evidence for the existence of a family of distinct enzymes
-
R.K. Harrison, and R.L. Stein Substrate specificities of the peptidyl prolyl cis-trans isomerase activities of cyclophilin and FK-506 binding protein: evidence for the existence of a family of distinct enzymes Biochemistry 29 1990 3813 3816
-
(1990)
Biochemistry
, vol.29
, pp. 3813-3816
-
-
Harrison, R.K.1
Stein, R.L.2
-
77
-
-
0026466860
-
A yeast cyclophilin gene essential for lactate metabolism at high temperature
-
E.S. Davis, A. Becker, J. Heitman, M.N. Hall, and M.B. Brennan A yeast cyclophilin gene essential for lactate metabolism at high temperature Proc. Natl. Acad. Sci. U. S. A. 89 1992 11169 11173
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 11169-11173
-
-
Davis, E.S.1
Becker, A.2
Heitman, J.3
Hall, M.N.4
Brennan, M.B.5
-
78
-
-
0035957915
-
Functional replacement of the essential ESS1 in yeast by the plant parvulin DlPar13
-
M. Metzner, G. Stoller, K.P. Rucknagel, K.P. Lu, G. Fischer, M. Luckner, and G. Kullertz Functional replacement of the essential ESS1 in yeast by the plant parvulin DlPar13 J. Biol. Chem. 276 2001 13524 13529
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 13524-13529
-
-
Metzner, M.1
Stoller, G.2
Rucknagel, K.P.3
Lu, K.P.4
Fischer, G.5
Luckner, M.6
Kullertz, G.7
-
79
-
-
0028124244
-
Confirmation of the existence of a third family among peptidyl-prolyl cis/trans isomerases. Amino acid sequence and recombinant production of parvulin
-
J.U. Rahfeld, K.P. Rucknagel, B. Schelbert, B. Ludwig, J. Hacker, K. Mann, and G. Fischer Confirmation of the existence of a third family among peptidyl-prolyl cis/trans isomerases. Amino acid sequence and recombinant production of parvulin FEBS Lett. 352 1994 180 184
-
(1994)
FEBS Lett.
, vol.352
, pp. 180-184
-
-
Rahfeld, J.U.1
Rucknagel, K.P.2
Schelbert, B.3
Ludwig, B.4
Hacker, J.5
Mann, K.6
Fischer, G.7
-
80
-
-
0026575932
-
The mechanism of action of cyclosporin a and FK506
-
S.L. Schreiber, and G.R. Crabtree The mechanism of action of cyclosporin A and FK506 Immunol. Today 13 1992 136 142
-
(1992)
Immunol. Today
, vol.13
, pp. 136-142
-
-
Schreiber, S.L.1
Crabtree, G.R.2
-
81
-
-
0029317904
-
Cyclin-dependent protein kinases: Key regulators of the eukaryote cell cycle
-
E.A. Nigg Cyclin-dependent protein kinases: key regulators of the eukaryote cell cycle BioEssays 17 1995 471 480
-
(1995)
BioEssays
, vol.17
, pp. 471-480
-
-
Nigg, E.A.1
-
82
-
-
0029043582
-
How MAP kinases are regulated
-
M.H. Cobb, and E.J. Goldsmith How MAP kinases are regulated J. Biol. Chem. 270 1995 14843 14846
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14843-14846
-
-
Cobb, M.H.1
Goldsmith, E.J.2
-
83
-
-
0031438929
-
Sequence-specific and phosphorylation-dependent proline isomerization: A potential mitotic regulatory mechanism
-
M.B. Yaffe, M. Schutkowski, M. Shen, X.Z. Zhou, P.T. Stukenberg, J. Rahfeld, J. Xu, J. Kuang, M.W. Kirschner, G. Fischer, L.C. Cantley, and K.P. Lu Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism Science 278 1997 1957 1960
-
(1997)
Science
, vol.278
, pp. 1957-1960
-
-
Yaffe, M.B.1
Schutkowski, M.2
Shen, M.3
Zhou, X.Z.4
Stukenberg, P.T.5
Rahfeld, J.6
Xu, J.7
Kuang, J.8
Kirschner, M.W.9
Fischer, G.10
Cantley, L.C.11
Lu, K.P.12
-
84
-
-
0032031634
-
The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins
-
M. Shen, P.T. Stukenberg, M.W. Kirschner, and K.P. Lu The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins Genes Dev. 12 1998 706 720
-
(1998)
Genes Dev.
, vol.12
, pp. 706-720
-
-
Shen, M.1
Stukenberg, P.T.2
Kirschner, M.W.3
Lu, K.P.4
-
85
-
-
0040017910
-
A function of WW domains as phosphoserine- or phosphothreonine-binding modules
-
P.J. Lu, X.Z. Zhou, M. Shen, and K.P. Lu A function of WW domains as phosphoserine- or phosphothreonine-binding modules Science 283 1999 1325 1328
-
(1999)
Science
, vol.283
, pp. 1325-1328
-
-
Lu, P.J.1
Zhou, X.Z.2
Shen, M.3
Lu, K.P.4
-
86
-
-
0034840950
-
Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC
-
A. Ryo, N. Nakamura, G. Wulf, Y.C. Liou, and K.P. Lu Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC Nat. Cell Biol. 3 2001 793 801
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 793-801
-
-
Ryo, A.1
Nakamura, N.2
Wulf, G.3
Liou, Y.C.4
Lu, K.P.5
-
87
-
-
0035796405
-
Pin1 is overexpressed in breast cancer and potentiates the transcriptional activity of phosphorylated c-Jun towards the cyclin D1 gene
-
G.M. Wulf, A. Ryo, G.G. Wulf, S.W. Lee, T. Niu, and K.P. Lu Pin1 is overexpressed in breast cancer and potentiates the transcriptional activity of phosphorylated c-Jun towards the cyclin D1 gene. EMBO J. 20 2001 3459 3472
-
(2001)
EMBO J.
, vol.20
, pp. 3459-3472
-
-
Wulf, G.M.1
Ryo, A.2
Wulf, G.G.3
Lee, S.W.4
Niu, T.5
Lu, K.P.6
-
88
-
-
0037169479
-
Critical role of WW domain phosphorylation in regulating its phosphoserine-binding activity and the Pin1 function
-
P.J. Lu, X.Z. Zhou, Y.C. Liou, J.P. Noel, and K.P. Lu Critical role of WW domain phosphorylation in regulating its phosphoserine-binding activity and the Pin1 function J. Biol. Chem. 277 2002 2381 2384
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2381-2384
-
-
Lu, P.J.1
Zhou, X.Z.2
Liou, Y.C.3
Noel, J.P.4
Lu, K.P.5
-
89
-
-
0037022355
-
Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes
-
Y.C. Liou, R. Ryo, H.K. Huang, P.J. Lu, R. Bronson, F. Fujimori, U. Uchidap, T. Hunter, and K.P. Lu Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes Proc. Natl. Acad. Sci. U. S. A. 99 2002 1335 1340
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 1335-1340
-
-
Liou, Y.C.1
Ryo, R.2
Huang, H.K.3
Lu, P.J.4
Bronson, R.5
Fujimori, F.6
Uchidap, U.7
Hunter, T.8
Lu, K.P.9
-
90
-
-
0037351048
-
Prolyl isomerase Pin1: A catalyst for oncogenesis and a potential therapeutic target in cancer
-
A. Ryo, Y.C. Liou, K.P. Lu, and G. Wulf Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer. J. Cell. Sci. 116 2003 773 783
-
(2003)
J. Cell. Sci.
, vol.116
, pp. 773-783
-
-
Ryo, A.1
Liou, Y.C.2
Lu, K.P.3
Wulf, G.4
-
91
-
-
0042476570
-
Pin1 regulates the timing of mammalian primordial germ cell proliferation
-
F.W. Atchison, B. Capel, and A.R. Means Pin1 regulates the timing of mammalian primordial germ cell proliferation Development 130 2003 3579 3586
-
(2003)
Development
, vol.130
, pp. 3579-3586
-
-
Atchison, F.W.1
Capel, B.2
Means, A.R.3
-
92
-
-
10944240265
-
Spermatogonial depletion in adult Pin1-deficient mice: Pin1 regulates the timing of mammalian primordial germ cell proliferation
-
F.W. Atchison, A.R. Means, and B. Capel Spermatogonial depletion in adult Pin1-deficient mice: Pin1 regulates the timing of mammalian primordial germ cell proliferation Biol. Reprod. 20 2003 20
-
(2003)
Biol. Reprod.
, vol.20
, pp. 20
-
-
Atchison, F.W.1
Means, A.R.2
Capel, B.3
-
93
-
-
0141885095
-
Pin1 is a novel prognostic marker in prostate cancer
-
G. Ayala, D. Wang, G. Wulf, A. Frolov, R. Le, T. Wheeler, J.M. Sowadski, K.P. Lu, and L. Bao Pin1 is a novel prognostic marker in prostate cancer Cancer Res. 63 2003 6244 6251
-
(2003)
Cancer Res.
, vol.63
, pp. 6244-6251
-
-
Ayala, G.1
Wang, D.2
Wulf, G.3
Frolov, A.4
Le, R.5
Wheeler, T.6
Sowadski, J.M.7
Lu, K.P.8
Bao, L.9
-
94
-
-
0033854422
-
Phosphorylation-dependent proline isomerization catalyzed by Pin1 is essential for tumor cell survival and entry into mitosis
-
J.F. Rippmann, S. Hobbie, C. Daiber, B. Guilliard, M. Bauer, J. Birk, H. Nar, P. Garin-Chesa, W.J. Rettig, and A. Schnapp Phosphorylation-dependent proline isomerization catalyzed by Pin1 is essential for tumor cell survival and entry into mitosis Cell Growth Differ. 11 2000 409 416
-
(2000)
Cell Growth Differ.
, vol.11
, pp. 409-416
-
-
Rippmann, J.F.1
Hobbie, S.2
Daiber, C.3
Guilliard, B.4
Bauer, M.5
Birk, J.6
Nar, H.7
Garin-Chesa, P.8
Rettig, W.J.9
Schnapp, A.10
-
95
-
-
0030062245
-
Mitotic mechanisms in Alzheimer's disease?
-
I. Vincent, M. Rosado, and P. Davies Mitotic mechanisms in Alzheimer's disease? J. Cell Biol. 132 1996 413 425
-
(1996)
J. Cell Biol.
, vol.132
, pp. 413-425
-
-
Vincent, I.1
Rosado, M.2
Davies, P.3
-
96
-
-
0031006939
-
Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain
-
I. Vincent, G. Jicha, M. Rosado, and D.W. Dickson Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain J. Neurosci. 17 1997 3588 3598
-
(1997)
J. Neurosci.
, vol.17
, pp. 3588-3598
-
-
Vincent, I.1
Jicha, G.2
Rosado, M.3
Dickson, D.W.4
-
97
-
-
0029824877
-
Alzheimer's disease neurofibrillary tangles contain mitosis-specific phosphoepitopes
-
C.M. Kondratick, and D.D. Vandre Alzheimer's disease neurofibrillary tangles contain mitosis-specific phosphoepitopes J. Neurochem. 67 1996 2405 2416
-
(1996)
J. Neurochem.
, vol.67
, pp. 2405-2416
-
-
Kondratick, C.M.1
Vandre, D.D.2
-
98
-
-
0031685160
-
Mitotic phosphoepitopes precede paired helical filaments in Alzheimer's disease
-
I. Vincent, J.H. Zheng, D.W. Dickson, Y. Kress, and P. Davies Mitotic phosphoepitopes precede paired helical filaments in Alzheimer's disease Neurobiol. Aging 19 1998 287 296
-
(1998)
Neurobiol. Aging
, vol.19
, pp. 287-296
-
-
Vincent, I.1
Zheng, J.H.2
Dickson, D.W.3
Kress, Y.4
Davies, P.5
-
99
-
-
0031928259
-
Mitotic phosphorylation of tau protein in neuronal cell lines resembles phosphorylation in Alzheimer's disease
-
U. Preuss, and E.M. Mandelkow Mitotic phosphorylation of tau protein in neuronal cell lines resembles phosphorylation in Alzheimer's disease Eur. J. Cell Biol. 76 1998 176 184
-
(1998)
Eur. J. Cell Biol.
, vol.76
, pp. 176-184
-
-
Preuss, U.1
Mandelkow, E.M.2
-
100
-
-
17044461433
-
The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: Implications for Alzheimer's disease
-
S. Illenberger, Q. Zheng-Fischhofer, U. Preuss, K. Stamer, K. Baumann, B. Trinczek, J. Biernat, R. Godemann, E.M. Mandelkow, and E. Mandelkow The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: implications for Alzheimer's disease Mol. Biol. Cell 9 1998 1495 1512
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 1495-1512
-
-
Illenberger, S.1
Zheng-Fischhofer, Q.2
Preuss, U.3
Stamer, K.4
Baumann, K.5
Trinczek, B.6
Biernat, J.7
Godemann, R.8
Mandelkow, E.M.9
Mandelkow, E.10
-
101
-
-
0035066999
-
Tracking of Alzheimer's disease progression with cerebrospinal fluid tau protein phosphorylated at threonine 231
-
H. Hampel, K. Buerger, R. Kohnken, S.J. Teipel, R. Zinkowski, H.J. Moeller, S.I. Rapoport, and P. Davies Tracking of Alzheimer's disease progression with cerebrospinal fluid tau protein phosphorylated at threonine 231 Ann. Neurol. 49 2001 545 546
-
(2001)
Ann. Neurol.
, vol.49
, pp. 545-546
-
-
Hampel, H.1
Buerger, K.2
Kohnken, R.3
Teipel, S.J.4
Zinkowski, R.5
Moeller, H.J.6
Rapoport, S.I.7
Davies, P.8
-
102
-
-
1242307774
-
The peptidyl prolyl cis/trans-isomerase Pin1 recognizes the phospho-Thr212-Pro213 site on Tau
-
C. Smet, A.V. Sambo, J.M. Wieruszeski, A. Leroy, I. Landrieu, L. Buee, and G. Lippens The peptidyl prolyl cis/trans-isomerase Pin1 recognizes the phospho-Thr212-Pro213 site on Tau Biochemistry 43 2004 2032 2040
-
(2004)
Biochemistry
, vol.43
, pp. 2032-2040
-
-
Smet, C.1
Sambo, A.V.2
Wieruszeski, J.M.3
Leroy, A.4
Landrieu, I.5
Buee, L.6
Lippens, G.7
-
103
-
-
0033558929
-
Sequence requirements for formation of conformational variants of tau similar to those found in Alzheimer's disease
-
G.A. Jicha, B. Berenfeld, and P. Davies Sequence requirements for formation of conformational variants of tau similar to those found in Alzheimer's disease J. Neurosci. Res. 55 1999 713 723
-
(1999)
J. Neurosci. Res.
, vol.55
, pp. 713-723
-
-
Jicha, G.A.1
Berenfeld, B.2
Davies, P.3
-
104
-
-
0030936599
-
Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau
-
G.A. Jicha, R. Bowser, I.G. Kazam, and P. Davies Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau J. Neurosci. Res. 48 1997 128 132
-
(1997)
J. Neurosci. Res.
, vol.48
, pp. 128-132
-
-
Jicha, G.A.1
Bowser, R.2
Kazam, I.G.3
Davies, P.4
-
105
-
-
0034254722
-
Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's disease
-
N.L. Daly, R. Hoffmann, L. Otvos Jr., and D.J. Craik Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's disease Biochemistry 39 2000 9039 9046
-
(2000)
Biochemistry
, vol.39
, pp. 9039-9046
-
-
Daly, N.L.1
Hoffmann, R.2
Otvos Jr., L.3
Craik, D.J.4
-
107
-
-
0034050649
-
Requirement of the prolyl isomerase Pin1 for the replication checkpoint
-
K.E. Winkler, K.I. Swenson, S. Kornbluth, and A.R. Means Requirement of the prolyl isomerase Pin1 for the replication checkpoint Science 287 2000 1644 1647
-
(2000)
Science
, vol.287
, pp. 1644-1647
-
-
Winkler, K.E.1
Swenson, K.I.2
Kornbluth, S.3
Means, A.R.4
-
108
-
-
0030462914
-
Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes
-
H.A. Lane, and E.A. Nigg Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes J. Cell Biol. 135 1996 1701 1713
-
(1996)
J. Cell Biol.
, vol.135
, pp. 1701-1713
-
-
Lane, H.A.1
Nigg, E.A.2
-
109
-
-
0032705499
-
The C-terminal domain of the Cdc2 inhibitory kinase Myt1 interacts with Cdc2 complexes and is required for inhibition of G(2)/M progression
-
N.J. Wells, N. Watanabe, T. Tokusumi, W. Jiang, M.A. Verdecia, and T. Hunter The C-terminal domain of the Cdc2 inhibitory kinase Myt1 interacts with Cdc2 complexes and is required for inhibition of G(2)/M progression J. Cell. Sci. 112 1999 3361 3371
-
(1999)
J. Cell. Sci.
, vol.112
, pp. 3361-3371
-
-
Wells, N.J.1
Watanabe, N.2
Tokusumi, T.3
Jiang, W.4
Verdecia, M.A.5
Hunter, T.6
-
110
-
-
0033635191
-
The cell cycle Cdc25A tyrosine phosphatase is activated in degenerating postmitotic neurons in Alzheimer's disease
-
X.L. Ding, J. Husseman, A. Tomashevski, D. Nochlin, L.W. Jin, and I. Vincent The cell cycle Cdc25A tyrosine phosphatase is activated in degenerating postmitotic neurons in Alzheimer's disease Am. J. Pathol. 157 2000 1983 1990
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 1983-1990
-
-
Ding, X.L.1
Husseman, J.2
Tomashevski, A.3
Nochlin, D.4
Jin, L.W.5
Vincent, I.6
-
111
-
-
0028924295
-
A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle
-
E. Sontag, V. Nunbhakdi-Craig, G.S. Bloom, and M.C. Mumby A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle J. Cell Biol. 128 1995 1131 1144
-
(1995)
J. Cell Biol.
, vol.128
, pp. 1131-1144
-
-
Sontag, E.1
Nunbhakdi-Craig, V.2
Bloom, G.S.3
Mumby, M.C.4
-
112
-
-
0029074207
-
The role of Saccharomyces cerevisiae type 2A phosphatase in the actin cytoskeleton and in entry into mitosis
-
F.C. Lin, and K.T. Arndt The role of Saccharomyces cerevisiae type 2A phosphatase in the actin cytoskeleton and in entry into mitosis EMBO J. 14 1995 2745 2759
-
(1995)
EMBO J.
, vol.14
, pp. 2745-2759
-
-
Lin, F.C.1
Arndt, K.T.2
-
113
-
-
0029348268
-
The role of protein phosphatase type-2A in the Xenopus cell cycle: Initiation of the G2/M transition
-
T.H. Lee The role of protein phosphatase type-2A in the Xenopus cell cycle: initiation of the G2/M transition Semin. Cancer Biol. 6 1995 203 209
-
(1995)
Semin. Cancer Biol.
, vol.6
, pp. 203-209
-
-
Lee, T.H.1
-
114
-
-
0024996931
-
Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle
-
N. Kinoshita, H. Ohkura, and M. Yanagida Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle Cell 63 1990 405 415
-
(1990)
Cell
, vol.63
, pp. 405-415
-
-
Kinoshita, N.1
Ohkura, H.2
Yanagida, M.3
-
115
-
-
0031031397
-
HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint
-
T. Kawabe, A.J. Muslin, and S.J. Korsmeyer HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint Nature 385 1997 454 458
-
(1997)
Nature
, vol.385
, pp. 454-458
-
-
Kawabe, T.1
Muslin, A.J.2
Korsmeyer, S.J.3
-
116
-
-
0031014433
-
Mutations in the Saccharomyces cerevisiae type 2A protein phosphatase catalytic subunit reveal roles in cell wall integrity, actin cytoskeleton organization and mitosis
-
D.R. Evans, and M.J. Stark Mutations in the Saccharomyces cerevisiae type 2A protein phosphatase catalytic subunit reveal roles in cell wall integrity, actin cytoskeleton organization and mitosis Genetics 145 1997 227 241
-
(1997)
Genetics
, vol.145
, pp. 227-241
-
-
Evans, D.R.1
Stark, M.J.2
-
117
-
-
0030444680
-
MHP1, an essential gene in Saccharomyces cerevisiae required for microtubule function
-
I. Irminger-Finger, E. Hurt, A. Roebuck, M.A. Collart, and S.J. Edelstein MHP1, an essential gene in Saccharomyces cerevisiae required for microtubule function J. Cell Biol. 135 1996 1323 1339
-
(1996)
J. Cell Biol.
, vol.135
, pp. 1323-1339
-
-
Irminger-Finger, I.1
Hurt, E.2
Roebuck, A.3
Collart, M.A.4
Edelstein, S.J.5
-
118
-
-
0031790436
-
Effect of microtubule-associated protein MHP1 on microtubule assembly and cell cycle progression in Saccharomyces cerevisiae
-
I. Irminger-Finger, and N. Mathis Effect of microtubule-associated protein MHP1 on microtubule assembly and cell cycle progression in Saccharomyces cerevisiae Cell Struct. Funct. 23 1998 209 219
-
(1998)
Cell Struct. Funct.
, vol.23
, pp. 209-219
-
-
Irminger-Finger, I.1
Mathis, N.2
-
119
-
-
0036938198
-
Inverse association of Pin1 and tau accumulation in Alzheimer's disease hippocampus
-
M. Holzer, U. Gartner, A. Stobe, W. Hartig, H. Gruschka, M.K. Bruckner, and T. Arendt Inverse association of Pin1 and tau accumulation in Alzheimer's disease hippocampus Acta Neuropathol. (Berl.) 104 2002 471 481
-
(2002)
Acta Neuropathol. (Berl.)
, vol.104
, pp. 471-481
-
-
Holzer, M.1
Gartner, U.2
Stobe, A.3
Hartig, W.4
Gruschka, H.5
Bruckner, M.K.6
Arendt, T.7
-
120
-
-
0026544937
-
The effect of age and Alzheimer's disease on pyramidal neuron density in the individual fields of the hippocampal formation
-
D.C. Davies, N. Horwood, S.L. Isaacs, and D.M. Mann The effect of age and Alzheimer's disease on pyramidal neuron density in the individual fields of the hippocampal formation Acta Neuropathol. (Berl.) 83 1992 510 517
-
(1992)
Acta Neuropathol. (Berl.)
, vol.83
, pp. 510-517
-
-
Davies, D.C.1
Horwood, N.2
Isaacs, S.L.3
Mann, D.M.4
-
121
-
-
0026743110
-
Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease
-
P.V. Arriagada, K. Marzloff, and B.T. Hyman Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease [see comments] Neurology 42 1992 1681 1688
-
(1992)
Neurology
, vol.42
, pp. 1681-1688
-
-
Arriagada, P.V.1
Marzloff, K.2
Hyman, B.T.3
-
122
-
-
0345512210
-
Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease
-
R.C. Pearson, M.M. Esiri, R.W. Hiorns, G.K. Wilcock, and T.P. Powell Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease Proc. Natl. Acad. Sci. U. S. A. 82 1985 4531 4534
-
(1985)
Proc. Natl. Acad. Sci. U. S. A.
, vol.82
, pp. 4531-4534
-
-
Pearson, R.C.1
Esiri, M.M.2
Hiorns, R.W.3
Wilcock, G.K.4
Powell, T.P.5
-
123
-
-
0025969656
-
Neocortical neuronal subpopulations labeled by a monoclonal antibody to calbindin exhibit differential vulnerability in Alzheimer's disease
-
P.R. Hof, and J.H. Morrison Neocortical neuronal subpopulations labeled by a monoclonal antibody to calbindin exhibit differential vulnerability in Alzheimer's disease Exp. Neurol. 111 1991 293 301
-
(1991)
Exp. Neurol.
, vol.111
, pp. 293-301
-
-
Hof, P.R.1
Morrison, J.H.2
-
124
-
-
0142157635
-
Pin1 colocalization with phosphorylated tau in Alzheimer's disease and other tauopathies
-
P. Ramakrishnan, D.W. Dickson, and P. Davies Pin1 colocalization with phosphorylated tau in Alzheimer's disease and other tauopathies Neurobiol. Dis. 14 2003 251 264
-
(2003)
Neurobiol. Dis.
, vol.14
, pp. 251-264
-
-
Ramakrishnan, P.1
Dickson, D.W.2
Davies, P.3
-
125
-
-
0036850725
-
Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein
-
B. Allen, E. Ingram, M. Takao, M.J. Smith, R. Jakes, K. Virdee, H. Yoshida, M. Holzer, M. Craxton, P.C. Emson, C. Atzori, A. Migheli, R.A. Crowther, B. Ghetti, M.G. Spillantini, and M. Goedert Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein J. Neurosci. 22 2002 9340 9351
-
(2002)
J. Neurosci.
, vol.22
, pp. 9340-9351
-
-
Allen, B.1
Ingram, E.2
Takao, M.3
Smith, M.J.4
Jakes, R.5
Virdee, K.6
Yoshida, H.7
Holzer, M.8
Craxton, M.9
Emson, P.C.10
Atzori, C.11
Migheli, A.12
Crowther, R.A.13
Ghetti, B.14
Spillantini, M.G.15
Goedert, M.16
-
126
-
-
0035680685
-
FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and Tau filaments in forebrain
-
F. Lim, F. Hernandez, J.J. Lucas, P. Gomez-Ramos, M.A. Moran, and J. Avila FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and Tau filaments in forebrain Mol. Cell. Neurosci. 18 2001 702 714
-
(2001)
Mol. Cell. Neurosci.
, vol.18
, pp. 702-714
-
-
Lim, F.1
Hernandez, F.2
Lucas, J.J.3
Gomez-Ramos, P.4
Moran, M.A.5
Avila, J.6
-
127
-
-
0038448924
-
Structural analysis of the mitotic regulator hPin1 in solution: Insights into domain architecture and substrate binding
-
E. Bayer, S. Goettsch, J.W. Mueller, B. Griewel, E. Guiberman, L.M. Mayr, and P. Bayer Structural analysis of the mitotic regulator hPin1 in solution: insights into domain architecture and substrate binding J. Biol. Chem. 278 2003 26183 26193
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26183-26193
-
-
Bayer, E.1
Goettsch, S.2
Mueller, J.W.3
Griewel, B.4
Guiberman, E.5
Mayr, L.M.6
Bayer, P.7
-
128
-
-
0028086441
-
Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion
-
L. Luo, Y.J. Liao, L.Y. Jan, and Y.N. Jan Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion Genes Dev. 8 1994 1787 1802
-
(1994)
Genes Dev.
, vol.8
, pp. 1787-1802
-
-
Luo, L.1
Liao, Y.J.2
Jan, L.Y.3
Jan, Y.N.4
-
129
-
-
0030026182
-
Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines
-
L. Luo, T.K. Hensch, L. Ackerman, S. Barbel, L.Y. Jan, and Y.N. Jan Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines Nature 379 1996 837 840
-
(1996)
Nature
, vol.379
, pp. 837-840
-
-
Luo, L.1
Hensch, T.K.2
Ackerman, L.3
Barbel, S.4
Jan, L.Y.5
Jan, Y.N.6
-
130
-
-
0034661746
-
Small GTPases Rac and Rho in the maintenance of dendritic spines and branches in hippocampal pyramidal neurons
-
A.Y. Nakayama, M.B. Harms, and L. Luo Small GTPases Rac and Rho in the maintenance of dendritic spines and branches in hippocampal pyramidal neurons J. Neurosci. 20 2000 5329 5338
-
(2000)
J. Neurosci.
, vol.20
, pp. 5329-5338
-
-
Nakayama, A.Y.1
Harms, M.B.2
Luo, L.3
|