Sequence requirements for formation of conformational variants of tau similar to those found in Alzheimer's disease

Journal of Neuroscience Research

Volumn 55, Issue 6, 1999, Pages 713-723

  Jicha, Gregory A ^a   Berenfeld, Benjamin ^a   Davies, Peter ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Conformation; Paired helical filament; Tau

Indexed keywords

EPITOPE; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; DEGENERATIVE DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN CONFORMATION;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ANTIBODY SPECIFICITY; ANTIGENS; BLOTTING, WESTERN; BRAIN; CLONING, MOLECULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOGLOBULIN G; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; TAU PROTEINS; VARIATION (GENETICS);

EID: 0033558929     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19990315)55:6<713::AID-JNR6>3.0.CO;2-G     Document Type: Article

References (36)

1. Brown RH Jr. 1995. Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice. Cell 80:687-692.
2. Carmel G, Mager EM, Binder LI, Kuret J. 1996. The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology. J Biol Chem 271:32789-32795.
3. Crowther RA, Olesen OF, Jakes R, Goedert M. 1992. The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease. FEBS Lett 309:199-202.
4. Crowther RA, Olesen OF, Smith MJ, Jakes R, Goedert M. 1994. Assembly of Alzheimer-like filaments from full-length tau protein. FEBS Lett 337:135-138.
5. DiFiglia M, Sapp E, Chase KO, Davies SW, Bates GP, Vonsattel JP, Aronin N. 1997. Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neuntes in brain. Science 277:1990-1993.
6. Feany MB, Dickson DW. 1996. Neurodegenerative disorders with extensive tau pathology: a comparitive study and review. Ann Neurol 40:139-148.
7. Goedert M, Spillantini MG, Jakes R, Rutherford D, Crowther RA. 1989. Multiple isoforms of human microtubule-associated protein-tau: sequences and localization in neurofibrillary tangles of Alzheimers-disease. Neuron 3:519-526.
8. Goedert M, Spillantini MG, Cairns NJ, Crowther RA. 1992. Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms. Neuron 8:159-168.
9. Goedert M, Jakes R, Spillantini MG, Hasegawa M, Smith MJ, Crowther RA. 1996. Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans. Nature 383:550-553.
10. Gonzalez PJ, Correas I, Avila J. 1992. Solubilization and fractionation of paired helical filaments. Neuroscience 50:491-499.
11. Grundke-Iqbal I, Iqbal K, Tung Y-C, Quinlan M, Wisniewski HM, Binder LI. 1986. Abnormal phosphorylation of the microtubule-associated protein tau in Alzheimer cytoskeletal pathology. Proc Natl Acad Sci USA 83:4913-4917.
12. Hirano K, Dembitzer HM, Kurland LT, Zimmerman HM. 1968. The fine structure of some intraganglionic alterations. Neurofibrillary tangles, granulovacuolar bodies, and "rod-like" structures as seen in Guam amyotrophic lateral sclerosis and parkinsonism-dementia complex. J Neuropath Exp Neurol 27:167-182.
13. Hoffman R, Lee VM-Y. Leight S Varga I, Otvos L Jr. 1997. Unique Alzheimer's disease paired helical filament specific epitopes involve double phosphorylation at specific sites. Biochemistry 36:8114-8124.
14. Hyman BT, Van Hoesen GW, Wolozin BL, Davies P, Kromer LJ, Damasio AR. 1988. Alz-50 antibody recognizes Alzheimer-related neuronal changes. Ann Neurol 23:371-379.
15. Jicha GA, Bowser R, Kazam IG, Davies P. 1997a. Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau. J Neurosci Res 48:128-132.
16. Jicha GA, Lane E, Vincent I, Otvos L Jr, Hoffman R, Davies P. 1997b. A conformation- and phosphorylation-dependent antibody recognizing the paired helical filaments of Alzheimer's disease. J Neurochem 69:2087-2095.
17. Kalra S, Bergeron C, Lang AE. 1996. Lewy body disease and dementia: a review. Arch Int Med 156:487-493.
18. Kanemaru K, Takio K, Mirua R, Titani K, Ihara Y. 1992. Fetal-type phosphorylation of the tau in paired helical filaments. J Neurochem 58:1667-1675.
19. Khachaturian ZS. 1985. Diagnosis of Alzheimer's disease. Arch Neurol 42:1097-1106.
20. Kosik K, Orecchio LD, Binder LI, Trojanowski JQ, Lee VM-Y, Lee G. 1988. Epitopes that span the tau molecule are shared with paired helical filaments. Neuron 1:817-825.
21. Ksiezak-Reding H, Morgan K, Mattiace LA, Davies P, Liu W-K, Yen S-H, Weidenheim K, Dickson DW. 1994. Ultrastructure and biochemical composition of paired helical filaments in cortico-basal degeneration. Am J Pathol 145:1496-1508.
22. Lee VM-Y, Balin B, Otvos L Jr, Trojanowski JQ. 1991. A68: a major subunit of paired helical filaments of derivatized forms of normal tau. Science 451:675-678.
23. McKenzie JE, Roberts GW, Royston MC. 1996. Comparative investigation of neurofibrillary damage in the temporal lobe in Alzheimer's disease, Down's syndrome, and dementia pugilistica. Neurodegeneration 5:259-264.
24. Morishima-Kawashima M, Hasegawa M, Takio K, Suzuki M, Yoshida H, Titani K, Ihara Y. 1995. Proline-directed and nonproline-directed phosphorylation of PHF-tau. J Biol Chem 270:823-829.
25. Murayama S, Mori H, Ihara Y, Tomonaga. 1990. Immunocytochemical and ultrastructural studies of Pick's disease. Ann Neurol 27:394-405.
26. Paulson HL, Perez MK, Trottier Y, Trojanowski JQ, Subramony SH, Das SS, Vig P, Mandel J-L, Fishbeck KH, and Pittman RN. 1997. Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3. Neuron 19:333-344.
27. Perez M, Valpuesta JM, Medina M, Montejo de Garcini E, Avila J. 1996. Polymerization of τ into filaments in the presence of heparin: the minimal sequence required for τ-τ interaction. J Neurochem 67:1183-1190.
28. Prusiner SB. 1996. Human prion diseases and neurodegeneration. Curr Top Microbiol Immunol 207:1-17.
29. Rouleau GA, Clark AW, Rooke K, Pramatarova A, Krizus A, Suchowersky O, Julien JP, Figliewicz, D. 1996. SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis. Ann Neurol 39:128-131.
30. Schweers O, Schonbrunn-Haneheck E, Marx A, Mandelkow E. 1994. Structural studies of tau protein and Alzheimer paired helical filaments show no evidence for β-structure. J Biol Chem 269:24290-24297.
31. Schweers O, Mandelkow E-M, Biernat J, Mandelkow E. 1995. Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein τ controls the in vitro assembly of paired helical filaments. Proc Natl Acad Sci USA 92:8463-8467.
32. Trojanowski JQ, Lee V M-Y. 1994. Paired helical filament τ in Alzheimer's disease: the kinase connection. Am J Pathol 144:449-453.
33. Trojanowski JQ, Lee VM-Y. 1995. Phosphorylation of paired helical filament tau in Alzheimer's disease neurofibrillary lesions: focusing on phosphatases. FASEB J 9:1570-1576.
34. Wille H, Drewes G, Biernat J, Mandelkow EM, Mandelkow E. 1992. Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro. J Cell Biol 118:573-584.
35. Wolozin BL, Davies P. 1987. Alzheimer-related neuronal protein A68: specificity and distribution. Ann Neurol 22:521-526.
36. Wood JG, Mirra S, Pollock NJ, Binder LI. 1986. Neurofibrillary tangles of Alzheimer's disease share antigenic determinants with the axonal microtubule-associated protein tau. Proc Natl Acad Sci USA 83:4040-4043.