Prolyl isomerase Pin1: A catalyst for oncogenesis and a potential therapeutic target in cancer

Journal of Cell Science

Volumn 116, Issue 5, 2003, Pages 773-783

  Ryo, Akihide ^a   Liou, Yih Cherng ^a   Lu, Kun Ping ^a   Wulf, Gerburg ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Oncogenesis; Phosphorylation; Pin 1; Post phosphorylation regulation; Prolyl isomerase; Signal transduction

Indexed keywords

ANTINEOPLASTIC AGENT; APC PROTEIN; BETA CATENIN; CIS TRANS ISOMERASE; CYCLIN D1; DNA; JUGLONE; PHOSPHOPROTEIN; PROLINE DERIVATIVE; PROTEIN P53; PROTEIN PIN 1; RAS PROTEIN; SERINE; THREONINE; TRANSCRIPTION FACTOR E2F; UNCLASSIFIED DRUG; WNT PROTEIN;

BREAST CELL; CARCINOGENESIS; CELL GROWTH; CELL TRANSFORMATION; CIS TRANS ISOMERISM; CONFORMATIONAL TRANSITION; DNA DAMAGE; DRUG MECHANISM; DRUG TARGETING; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; MITOGENICITY; NONHUMAN; ONCOGENE NEU; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; BETA CATENIN; CATALYSIS; CYCLIN D1; CYTOSKELETAL PROTEINS; DNA DAMAGE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASMS; PEPTIDYLPROLYL ISOMERASE; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0037351048     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.00276     Document Type: Review

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