Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 6, 2000, Pages 2910-2915

  Ahlijanian, Michael K ^a   Barrezueta, Nestor X ^a   Williams, Robert D ^a   Jakowski, Amy ^a   Kowsz, Kim P ^a   McCarthy, Sheryl ^a   Coskran, Timothy ^a   Carlo, Anthony ^a   Seymour, Patricia A ^a   Burkhardt, John E ^a   Nelson, Robert B ^a   McNeish, John D ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; ENZYME ACTIVATOR; ISOENZYME; NEUROFILAMENT PROTEIN; PROTEIN P25; TAU PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CELL DAMAGE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; CYTOSKELETON; DEGENERATIVE DISEASE; ENZYME ACTIVITY; MOUSE; NEUROFILAMENT; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSGENIC MOUSE;

AGE FACTORS; ALZHEIMER DISEASE; ANIMALS; BRAIN; CYCLIN-DEPENDENT KINASE 5; CYCLIN-DEPENDENT KINASES; CYTOSKELETON; EPITOPES; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON; NERVE TISSUE PROTEINS; NEUROFILAMENT PROTEINS; PHOSPHORYLATION; SEX FACTORS; SILVER STAINING; TAU PROTEINS;

ANIMALIA; MUS MUSCULUS;

EID: 12944268979     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.040577797     Document Type: Article

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