Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1

EMBO Journal

Volumn 20, Issue 13, 2001, Pages 3459-3472

  Wulf, Gerburg M ^a   Ryo, Akihide ^a   Wulf, Gerald G ^b   Lee, Sam W ^a   Niu, Tianhua ^c   Petkova, Victoria ^a   Lu, Kun Ping ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

c Jun; Cancer; Cyclin D1; Pin1; Ras signaling

Indexed keywords

ACTIN; CYCLIN D1; ESTROGEN RECEPTOR; ISOMERASE; MESSENGER RNA; PEPTIDYLPROLYL ISOMERASE PIN1; PROLINE; PROLYL ISOMERASE; RAS PROTEIN; SERINE; THREONINE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CONTROLLED STUDY; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; ONCOGENE C JUN; ONCOGENE H RAS; ONCOGENE NEU; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; TUMOR GROWTH;

ADULT; AGED; AGED, 80 AND OVER; BREAST; BREAST NEOPLASMS; CARCINOMA IN SITU; CELLS, CULTURED; CYCLIN D1; FEMALE; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDYLPROLYL ISOMERASE; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-JUN; RAS PROTEINS; RECEPTOR, ERBB-2; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 0035796405     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.13.3459     Document Type: Article

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