-
1
-
-
0038613248
-
Serotonin receptors and drugs affecting serotonergic neurotransmission
-
Williams, D. A., Lemke, T. M., Eds.; Lippincott Williams & Wilkins: Philadelphia, PA
-
Glennon, R. A.; Dukat, M. Serotonin receptors and drugs affecting serotonergic neurotransmission. In Foye's Principles of Medicinal Chemistry; Williams, D. A., Lemke, T. M., Eds.; Lippincott Williams & Wilkins: Philadelphia, PA, 2002; pp 315-337.
-
(2002)
Foye's Principles of Medicinal Chemistry
, pp. 315-337
-
-
Glennon, R.A.1
Dukat, M.2
-
2
-
-
0036119338
-
Molecular, pharmacological and functional diversity of 5-HT receptors
-
Hoyer, D.; Hannon, J. P.; Martin, G. R. Molecular, pharmacological and functional diversity of 5-HT receptors. Pharmacol. Biochem. Behav. 2002, 71, 533-554.
-
(2002)
Pharmacol. Biochem. Behav.
, vol.71
, pp. 533-554
-
-
Hoyer, D.1
Hannon, J.P.2
Martin, G.R.3
-
3
-
-
0036599358
-
Molecular biology of serotonin receptors - Structure and function at the molecular level
-
Kroeze, W. K.; Kristiansen, K.; Roth, B. L. Molecular biology of serotonin receptors - Structure and function at the molecular level. Curr. Top. Med. Chem. 2002, 2, 507-528.
-
(2002)
Curr. Top. Med. Chem.
, vol.2
, pp. 507-528
-
-
Kroeze, W.K.1
Kristiansen, K.2
Roth, B.L.3
-
4
-
-
0027233748
-
A new nomenclature for 5-HT receptors
-
Humphrey, P. P. A.; Hartig, P. R.; Hoyer, D. A new nomenclature for 5-HT receptors. Trends Pharmacol. Sci. 1993, 14, 233-236.
-
(1993)
Trends Pharmacol. Sci.
, vol.14
, pp. 233-236
-
-
Humphrey, P.P.A.1
Hartig, P.R.2
Hoyer, D.3
-
5
-
-
0032970989
-
A review of central 5-HT receptors and their function
-
Barnes, N. M.; Sharp, T. A review of central 5-HT receptors and their function. Neuropharmacology 1999, 38, 1083-1152.
-
(1999)
Neuropharmacology
, vol.38
, pp. 1083-1152
-
-
Barnes, N.M.1
Sharp, T.2
-
7
-
-
0027339423
-
5B receptors define a new family of serotonin receptors: Cloning, functional expression, and chromosomal localization
-
5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization. Mol. Pharmacol. 1993, 43, 313-319.
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 313-319
-
-
Matthes, H.1
Boschert, U.2
Amlaiky, N.3
Grailhe, R.4
Plassat, J.L.5
Muscatelli, F.6
Mattei, M.G.7
Hen, R.8
-
8
-
-
0027417598
-
Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain
-
Erlander, M. G.; Lovenberg, T. W.; Baron, B. M.; deLeccea, L.; Danielson, P. E.; Racke, M.; Slone, A. L.; Siegel, B. W.; Foye, P. E.; Cannon, K.; Burns, J. E.; Sutcliffe, J. G. Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 3452-3456.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A
, vol.90
, pp. 3452-3456
-
-
Erlander, M.G.1
Lovenberg, T.W.2
Baron, B.M.3
DeLeccea, L.4
Danielson, P.E.5
Racke, M.6
Slone, A.L.7
Siegel, B.W.8
Foye, P.E.9
Cannon, K.10
Burns, J.E.11
Sutcliffe, J.G.12
-
9
-
-
0027371568
-
5B receptor
-
5B receptor. FEBS Lett. 1993, 333, 25-31.
-
(1993)
FEBS Lett.
, vol.333
, pp. 25-31
-
-
Wisden, W.1
Parker, E.M.2
Mahle, C.D.3
Grisel, D.A.4
Nowak, H.P.5
Yocca, F.D.6
Felder, C.C.7
Seeburg, P.H.8
Voight, M.M.9
-
10
-
-
0028063557
-
5A serotonin receptor
-
5A serotonin receptor. FEBS Lett. 1994, 355, 242-246.
-
(1994)
FEBS Lett.
, vol.355
, pp. 242-246
-
-
Rees, S.1
Den Daas, I.2
Foord, S.3
Goodson, S.4
Bull, D.5
Kilpatrick, G.6
Lee, M.7
-
12
-
-
0032534320
-
Putative 5-ht5 receptors: Localization in the mouse CNS and lack of effect in the inhibition of dural protein extravasation
-
Waeber, C.; Grailhe, R.; Yu, X. J.; Hen, R.; Moskowitz, M. A. Putative 5-ht5 receptors: localization in the mouse CNS and lack of effect in the inhibition of dural protein extravasation. Ann. N. Y. Acad. Sci. 1998, 861, 85-90.
-
(1998)
Ann. N. Y. Acad. Sci.
, vol.861
, pp. 85-90
-
-
Waeber, C.1
Grailhe, R.2
Yu, X.J.3
Hen, R.4
Moskowitz, M.A.5
-
13
-
-
0029658014
-
-
Carson, M. J.; Thomas, E. J.; Danielson, P. A.; Sutcliffe, J. G. Glia 1996, 17, 317-326.
-
(1996)
Glia
, vol.17
, pp. 317-326
-
-
Carson, M.J.1
Thomas, E.J.2
Danielson, P.A.3
Sutcliffe, J.G.4
-
15
-
-
0033103167
-
5A receptor
-
5A receptor. Neuron 1999, 22, 581-591.
-
(1999)
Neuron
, vol.22
, pp. 581-591
-
-
Grailhe, R.1
Waeber, C.2
Dulawa, S.C.3
Hornung, J.P.4
Zhuang, X.5
Brunner, D.6
Geyer, M.A.7
Hen, R.8
-
16
-
-
0012820694
-
5A gene in depression, psychosis and antipsychotic response
-
5A gene in depression, psychosis and antipsychotic response. NeuroReport 2000, 11, 2017-2020.
-
(2000)
NeuroReport
, vol.11
, pp. 2017-2020
-
-
Birkett, J.T.1
Arranz, M.J.2
Munro, J.3
Osbourn, S.4
Kerwin, R.W.5
Collier, D.A.6
-
17
-
-
0035805385
-
5A receptor gene in patients with bipolar disorder and major depression
-
5A receptor gene in patients with bipolar disorder and major depression. Neurosci. Lett. 2001, 303, 111-114.
-
(2001)
Neurosci. Lett.
, vol.303
, pp. 111-114
-
-
Arias, B.1
Collier, D.A.2
Gasto, C.3
Pintor, L.4
Gutierrez, B.5
Valles, V.6
Fananas, L.7
-
18
-
-
0037937016
-
-
The Psychoactive Drug Screening Program Database can be found at http://pdsp.cwru.edu/pdsp.asp.
-
-
-
-
19
-
-
0000307776
-
5A serotonin receptor binding: A preliminary structure-affinity investigation
-
5A serotonin receptor binding: A preliminary structure-affinity investigation. Med. Chem. Res. 1997, 7, 207-218.
-
(1997)
Med. Chem. Res.
, vol.7
, pp. 207-218
-
-
Teitler, M.1
Scheick, C.2
Howard, P.3
Sullivan, J.E.4
Iwamura, T.5
Glennon, R.A.6
-
21
-
-
0038274305
-
5A receptors
-
Hampton, VA, May 22-24, (abstract in the following: Va. J. Sci. 2002, 53, 98.)
-
5A receptors. Presented at the 80th Annual Virginia Academy of Sciences Meeting, Hampton, VA, May 22-24, 2002 (abstract in the following: Va. J. Sci. 2002, 53, 98.).
-
(2002)
80th Annual Virginia Academy of Sciences Meeting
-
-
Khorana, N.1
Dukat, M.2
Teitler, M.3
Glennon, R.A.4
-
22
-
-
0027481384
-
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs
-
Monsma, F. J.; Shen, Y.; Ward, R. P.; Hamblin, M. W.; Sibley, D. R. Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Mol. Pharmacol. 1993, 43, 320-327.
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 320-327
-
-
Monsma, F.J.1
Shen, Y.2
Ward, R.P.3
Hamblin, M.W.4
Sibley, D.R.5
-
23
-
-
0028293526
-
Characterization of a 5-hydroxytryptamine receptor in mouse neuroblastoma N18TG2 cells
-
Unsworth, C. D.; Molinoff, P. B. Characterization of a 5-hydroxytryptamine receptor in mouse neuroblastoma N18TG2 cells. J. Pharmacol. Exp. Ther. 1994, 269, 246-255.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.269
, pp. 246-255
-
-
Unsworth, C.D.1
Molinoff, P.B.2
-
24
-
-
13344275875
-
6 serotonin receptor
-
6 serotonin receptor. J. Neurochem. 1996, 66, 47-56.
-
(1996)
J. Neurochem.
, vol.66
, pp. 47-56
-
-
Kohen, R.1
Metcalf, M.A.2
Khan, N.3
Druck, T.4
Huebner, K.5
Lachowicz, J.E.6
Meltzer, H.Y.7
Sibley, D.R.8
Roth, B.L.9
Hamblin, M.W.10
-
25
-
-
0028261434
-
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors
-
Roth, B. L.; Craigo, S. C.; Choudhary, M. S.; Uluer, A.; Monsma, F. J.; Shen, Y.; Meltzer, H. Y.; Sibley, D. R. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J. Pharmacol. Exp. Ther. 1994, 268, 1403-1410.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.268
, pp. 1403-1410
-
-
Roth, B.L.1
Craigo, S.C.2
Choudhary, M.S.3
Uluer, A.4
Monsma, F.J.5
Shen, Y.6
Meltzer, H.Y.7
Sibley, D.R.8
-
26
-
-
0031748656
-
Characterization of Ro 04-6790 and Ro 63-0563: Potent and selective antagonists at human and rat 5-HT6 receptors
-
Sleight, A. J.; Boess, F. G.; Bös, M.; Levet-Trafit, B.; Riemer, C.; Bourson, A. Characterization of Ro 04-6790 and Ro 63-0563: Potent and selective antagonists at human and rat 5-HT6 receptors. Br. J. Pharmacol. 1998, 124, 556-562.
-
(1998)
Br. J. Pharmacol.
, vol.124
, pp. 556-562
-
-
Sleight, A.J.1
Boess, F.G.2
Bös, M.3
Levet-Trafit, B.4
Riemer, C.5
Bourson, A.6
-
27
-
-
0032960693
-
6 receptor antagonist
-
6 receptor antagonist. J. Med. Chem. 1999, 42, 202-205.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 202-205
-
-
Bromidge, S.M.1
Brown, A.M.2
Clarke, S.E.3
Dodgson, K.4
Gager, T.5
Grassam, H.L.6
Jeffrey, P.M.7
Joiner, G.F.8
King, F.D.9
Middlemiss, D.N.10
Moss, S.F.11
Newman, H.12
Riley, G.13
Routledge, C.14
Wyman, P.15
-
28
-
-
0034675393
-
6 antagonists
-
6 antagonists. Bioorg. Med. Chem. Lett. 2000, 10, 2295-2299.
-
(2000)
Bioorg. Med. Chem. Lett.
, vol.10
, pp. 2295-2299
-
-
Tsai, Y.1
Dukat, M.2
Slassi, A.3
MacLean, N.4
Demchyshyn, L.5
Savage, J.E.6
Roth, B.L.7
Hufesein, S.8
Lee, M.9
Glennon, R.A.10
-
29
-
-
0034624773
-
6 serotonin receptors
-
6 serotonin receptors. J. Med. Chem. 2000, 43, 1011-1018.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 1011-1018
-
-
Glennon, R.A.1
Lee, M.2
Rangisetty, J.B.3
Dukat, M.4
Roth, B.L.5
Savage, J.E.6
McBride, A.7
Rauser, L.8
Hufesien, L.9
Lee, D.K.H.10
-
30
-
-
0035246514
-
6 receptor antagonists: Lead optimization and biological evaluation of N-aryl and N-heteroaryl 4-aminobenzene sulfonamides
-
6 receptor antagonists: Lead optimization and biological evaluation of N-aryl and N-heteroaryl 4-aminobenzene sulfonamides. Eur. J. Med. Chem. 2001, 36, 165-178.
-
(2001)
Eur. J. Med. Chem.
, vol.36
, pp. 165-178
-
-
Bös, M.1
Sleight, A.J.2
Godel, T.3
Martin, J.R.4
Riemer, C.5
Stadler, H.6
-
31
-
-
0031595682
-
3H]Ro 63-0563 labels 5-hydroxytryptamine receptor binding sites in rat and porcine striatum
-
3H]Ro 63-0563 labels 5-hydroxytryptamine receptor binding sites in rat and porcine striatum. Mol. Pharmacol. 1998, 54, 577-583.
-
(1998)
Mol. Pharmacol.
, vol.54
, pp. 577-583
-
-
Boess, F.G.1
Riemer, C.2
Bös, M.3
Bentley, J.4
Bourson, A.5
Sleight, A.J.6
-
32
-
-
0035825334
-
Phenyl benzenesulfonamides are novel and selective 5-HT6 antagonists: Identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzene-sulfonamide (SB-357134)
-
Bromidge, S. M.; Clarke, S. E.; Gager, T.; Griffith, K.; Jeffrey, P.; Jennings, A. J.; Joiner, G. F.; King, F. D.; Lovell, P. J.; Moss, S. F.; Newman, H.; Riley, G.; Rogers, D.; Routledge, C.; Serafinowska, H.; Smith, D. R. Phenyl benzenesulfonamides are novel and selective 5-HT6 antagonists: Identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzene-sulfonamide (SB-357134). Bioorg. Med. Chem. Lett. 2001, 11, 55-58.
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 55-58
-
-
Bromidge, S.M.1
Clarke, S.E.2
Gager, T.3
Griffith, K.4
Jeffrey, P.5
Jennings, A.J.6
Joiner, G.F.7
King, F.D.8
Lovell, P.J.9
Moss, S.F.10
Newman, H.11
Riley, G.12
Rogers, D.13
Routledge, C.14
Serafinowska, H.15
Smith, D.R.16
-
33
-
-
18344373999
-
5 receptor antagonists
-
5 receptor antagonists. Bioorg. Med. Chem. Lett. 2002, 12, 1357-1360.
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 1357-1360
-
-
Bromidge, S.M.1
Clarke, S.E.2
King, F.D.3
Lovell, P.J.4
Newman, H.5
Riley, G.6
Routledge, C.7
Serafinowska, H.8
Smith, D.R.9
Thomas, D.R.10
-
34
-
-
0036225559
-
Recent progress in 5-HT6 receptor antagonists for the treatment of CNS diseases
-
Slassi, A.; Isaac, M.; O'Brien, A. Recent progress in 5-HT6 receptor antagonists for the treatment of CNS diseases. Expert Opin. Ther. Pat. 2002, 12, 513-527.
-
(2002)
Expert Opin. Ther. Pat.
, vol.12
, pp. 513-527
-
-
Slassi, A.1
Isaac, M.2
O'Brien, A.3
-
35
-
-
0033624158
-
125I]-SB-258585 binding to human recombinant and native 5-HT6 receptors in rat, pig and human brain tissue
-
125I]-SB-258585 binding to human recombinant and native 5-HT6 receptors in rat, pig and human brain tissue. Br. J. Pharmacol. 2000, 130, 1597-1605.
-
(2000)
Br. J. Pharmacol.
, vol.130
, pp. 1597-1605
-
-
Hirst, W.D.1
Minton, J.A.2
Bromidge, S.M.3
Moss, S.F.4
Latter, A.J.5
Riley, G.6
Routledge, C.7
Middlemiss, D.N.8
Price, G.W.9
-
36
-
-
0032912621
-
6 serotonin receptor binding of indolealkylamines: A preliminary structure-affinity investigation
-
6 serotonin receptor binding of indolealkylamines: A preliminary structure-affinity investigation. Med. Chem. Res. 1999, 9, 108-117.
-
(1999)
Med. Chem. Res.
, vol.9
, pp. 108-117
-
-
Glennon, R.A.1
Bondarev, M.2
Roth, B.L.3
-
37
-
-
0034487697
-
6 serotonin receptor binding affinities of N1-benzenesulfonyl and related tryptamines
-
6 serotonin receptor binding affinities of N1-benzenesulfonyl and related tryptamines. Med. Chem. Res. 2000, 10, 230-242.
-
(2000)
Med. Chem. Res.
, vol.10
, pp. 230-242
-
-
Lee, M.1
Rangisetty, J.B.2
Dukat, M.3
Slassi, A.4
MacLean, N.5
Lee, D.K.H.6
Glennon, R.A.7
-
38
-
-
0035829428
-
6 receptor ligands
-
6 receptor ligands. J. Med. Chem. 2001, 44, 3881-3895.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 3881-3895
-
-
Russell, M.G.N.1
Baker, R.J.2
Barden, L.3
Beer, M.S.4
Bristow, L.5
Broughton, H.B.6
Knowles, M.7
McAllister, G.8
Patel, S.9
Castro, J.L.10
-
41
-
-
0034599555
-
6) receptor gene in bipolar affective disorder and schizophrenia
-
6) receptor gene in bipolar affective disorder and schizophrenia. Am. J. Med. Genet. 2000, 96, 217-221.
-
(2000)
Am. J. Med. Genet.
, vol.96
, pp. 217-221
-
-
Vogt, I.R.1
Shimron-Abarbanell, D.2
Neidt, H.3
Erdmann, J.4
Cichon, S.5
Schulze, T.G.6
Muller, D.J.7
Maier, W.8
Albus, M.9
Borrmann-Hassenbach, M.10
Knapp, M.11
Rietschel, M.12
Propping, P.13
Nothen, M.M.14
-
42
-
-
0036119234
-
6 receptor antagonist, SB-271046, in animal models for schizophrenia
-
6 receptor antagonist, SB-271046, in animal models for schizophrenia. Pharmacol. Biochem. Behav. 2002, 71, 635-643.
-
(2002)
Pharmacol. Biochem. Behav.
, vol.71
, pp. 635-643
-
-
Pouzet, B.1
Didriksen, M.2
Arnt, J.3
-
47
-
-
0034740154
-
6 receptor antagonists enhance retention of a water maze task in the rat
-
6 receptor antagonists enhance retention of a water maze task in the rat. Psychopharmacology (Berlin) 2001, 158, 114-119.
-
(2001)
Psychopharmacology (Berlin)
, vol.158
, pp. 114-119
-
-
Rogers, D.C.1
Hagan, J.J.2
-
49
-
-
0034782825
-
6 receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus
-
6 receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus. Neuropsychopharmacology 2001, 25, 662-668.
-
(2001)
Neuropsychopharmacology
, vol.25
, pp. 662-668
-
-
Dawson, L.A.1
Nguyen, H.Q.2
Li, P.3
-
50
-
-
0036125527
-
6 receptor antagonist
-
6 receptor antagonist. Pharmacol. Biochem. Behav. 2002, 71, 645-654.
-
(2002)
Pharmacol. Biochem. Behav.
, vol.71
, pp. 645-654
-
-
Stean, T.O.1
Hirst, W.D.2
Thomas, D.R.3
Price, G.W.4
Rogers, D.5
Riley, G.6
Bromidge, S.M.7
Serafinowska, H.T.8
Smith, D.R.9
Bartlett, S.10
Deeks, N.11
Duxon, M.12
Upton, N.13
-
51
-
-
0033854822
-
6 receptor antagonist
-
6 receptor antagonist. Br. J. Pharmacol. 2000, 130, 1606-1612.
-
(2000)
Br. J. Pharmacol.
, vol.130
, pp. 1606-1612
-
-
Routledge, C.1
Bromidge, S.M.2
Moss, S.F.3
Price, G.W.4
Hirst, W.5
Newman, H.6
Riley, G.7
Gager, T.8
Stean, T.9
Upton, N.10
Clarke, S.E.11
Brown, A.M.12
Middlemiss, D.N.13
-
54
-
-
0027282204
-
7 serotonin receptor subtype
-
7 serotonin receptor subtype. J. Biol. Chem. 1993, 268, 18200-18204.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 18200-18204
-
-
Shen, Y.1
Monsma F.J., Jr.2
Metcalf, M.A.3
Jose, P.A.4
Hamblin, M.W.5
Sibley, D.R.6
-
55
-
-
0027368668
-
7) implicated in the regulation of mammalian circadian rhythms
-
7) implicated in the regulation of mammalian circadian rhythms. Neuron 1993, 11, 449-458.
-
(1993)
Neuron
, vol.11
, pp. 449-458
-
-
Lovenberg, T.W.1
Baron, B.M.2
De Lecea, L.3
Miller, J.D.4
Prosser, R.A.5
Rea, M.A.6
Foye, P.E.7
Racke, M.8
Slone, A.L.9
Siegel, B.W.10
Danielson, P.E.11
Sutcliffe, J.G.12
Erlander, M.G.13
-
56
-
-
0027183389
-
7) activating cAMP formation
-
7) activating cAMP formation. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 8547-8551.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 8547-8551
-
-
Ruat, M.1
Traiffort, E.2
Leurs, R.3
Tardivel-Lacombe, J.4
Diaz, J.5
Arrang, J.M.6
Schwartz, J.C.7
-
57
-
-
0027186438
-
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase
-
Plassat, J.-L.; Amlaiky, N.; Hen, R. Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Mol. Pharmacol. 1993, 44, 229-236.
-
(1993)
Mol. Pharmacol.
, vol.44
, pp. 229-236
-
-
Plassat, J.-L.1
Amlaiky, N.2
Hen, R.3
-
58
-
-
0028168584
-
7 receptor positively coupled to adenylyl cyclase
-
7 receptor positively coupled to adenylyl cyclase. J. Neurochem. 1994, 63, 456-464.
-
(1994)
J. Neurochem.
, vol.63
, pp. 456-464
-
-
Tsou, A.P.1
Kosaka, A.2
Bach, C.3
Zuppan, P.4
Yee, C.5
Tom, L.6
Alvarez, R.7
Ramsey, S.8
Bonhaus, D.W.9
Stefanich, E.10
Jakeman, E.11
Eglen, R.M.12
Chan, H.W.13
-
60
-
-
0027421620
-
7) positively linked to adenylate cyclase
-
7) positively linked to adenylate cyclase. J. Biol. Chem. 1993, 268, 23422-23426.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 23422-23426
-
-
Bard, J.A.1
Zgombick, J.2
Adham, N.3
Vaysse, P.4
Brancheck, T.A.5
Weinshank, R.L.6
-
62
-
-
0030767784
-
7 receptor: Cloning and pharmacological characterization of two receptor variants
-
7 receptor: Cloning and pharmacological characterization of two receptor variants. FEBS Lett. 1997, 413, 489-494.
-
(1997)
FEBS Lett.
, vol.413
, pp. 489-494
-
-
Stam, N.J.1
Roesink, C.2
Dijcks, F.3
Garritsen, A.4
Van Herpen, A.5
Olijve, W.6
-
63
-
-
0030610194
-
7) receptor isoforms in human and rat produced by alternative splicing: Species differences due to altered intron-exon organization
-
7) receptor isoforms in human and rat produced by alternative splicing: species differences due to altered intron-exon organization. J. Neurochem. 1997, 68, 1372-1381.
-
(1997)
J. Neurochem.
, vol.68
, pp. 1372-1381
-
-
Heidmann, D.E.1
Metcalf, M.A.2
Kohen, R.3
Hamblin, M.W.4
-
65
-
-
0035024772
-
7 receptor splice variants: A comparative characterization of their pharmacology, function and distribution
-
7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution. Naunyn-Schmiedeberg's Arch. Pharmacol. 2001, 363, 620-632.
-
(2001)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.363
, pp. 620-632
-
-
Krobert, K.A.1
Bach, T.2
Syversveen, T.3
Kvingedal, A.M.4
Levy, F.O.5
-
66
-
-
15144342436
-
7 receptor (long form); antagonist profile of SB-258719
-
7 receptor (long form); antagonist profile of SB-258719. Br. J. Pharmacol. 1998, 124, 1300-1306.
-
(1998)
Br. J. Pharmacol.
, vol.124
, pp. 1300-1306
-
-
Thomas, D.R.1
Gittins, S.A.2
Collin, L.L.3
Middlemiss, D.N.4
Riley, G.5
Hagan, J.6
Gloger, I.7
Ellis, C.E.8
Forbes, I.T.9
Brown, A.M.10
-
67
-
-
0036009759
-
The human 5-HT7 serotonin receptor splice variants: Constitutive activity and inverse agonist effects
-
Krobert, K. A.; Levy, F. O. The human 5-HT7 serotonin receptor splice variants: constitutive activity and inverse agonist effects. Br. J. Pharmacol. 2002, 135, 1563-1571.
-
(2002)
Br. J. Pharmacol.
, vol.135
, pp. 1563-1571
-
-
Krobert, K.A.1
Levy, F.O.2
-
68
-
-
0036598964
-
2A antagonists
-
2A antagonists. Curr. Top. Med. Chem. 2002, 2, 539-558.
-
(2002)
Curr. Top. Med. Chem.
, vol.2
, pp. 539-558
-
-
Glennon, R.A.1
Metwally, K.2
Dukat, M.3
Ismaiel, A.M.4
De los Angeles, J.5
Herndon, J.6
Teitler, M.7
Khorana, N.8
-
69
-
-
18244431670
-
7 receptor antagonist
-
7 receptor antagonist. J. Med. Chem. 1998, 41, 655-657.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 655-657
-
-
Forbes, I.T.1
Dabbs, S.2
Duckworth, D.M.3
Jennings, A.J.4
King, F.D.5
Lovell, P.J.6
Brown, A.M.7
Collin, L.8
Hagan, J.J.9
Middlemiss, D.N.10
Riley, G.J.11
Thomas, D.R.12
Upton, N.13
-
70
-
-
0034628555
-
7 antagonist: (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970)
-
7 antagonist: (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970). J. Med. Chem. 2000, 43, 342-345.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 342-345
-
-
Lovell, P.J.1
Bromidge, S.M.2
Dabbs, S.3
Duckworth, D.M.4
Forbes, I.T.5
Jennings, A.J.6
King, F.D.7
Middlemiss, D.N.8
Rahman, S.K.9
Saunders, D.V.10
Collin, L.L.11
Hagan, J.J.12
Riley, G.J.13
Thomas, D.R.14
-
71
-
-
18644367263
-
7 receptor antagonist with improved in vivo properties
-
7 receptor antagonist with improved in vivo properties. Bioorg. Med. Chem. Lett. 2002, 12, 3341-3344.
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 3341-3344
-
-
Forbes, I.T.1
Douglas, S.2
Gribble, A.D.3
Ife, R.J.4
Lightfoot, A.P.5
Garner, A.E.6
Riley, G.J.7
Jeffrey, P.8
Stevens, A.J.9
Stean, T.O.10
Thomas, D.R.11
-
73
-
-
0037161613
-
7 receptor
-
7 receptor, J. Med. Chem. 2002, 45, 2197-2206.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 2197-2206
-
-
Kikuchi, C.1
Ando, T.2
Watanabe, T.3
Nagaso, H.4
Okuno, M.5
Hiranuma, T.6
Koyama, M.7
-
74
-
-
0035953317
-
7 receptor antagonists
-
7 receptor antagonists. J. Med. Chem. 2001, 44, 1337-1340.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 1337-1340
-
-
Linnanen, T.1
Brisander, M.2
Unelius, L.3
Rosqvist, S.4
Nordvall, G.5
Hacksell, U.6
Johansson, A.M.7
-
75
-
-
0034611592
-
Derivatives of (R)-1,11-methyleneaporphine: Synthesis, structure, and interactions with G-protein coupled receptors
-
Linnanen, T.; Brisander, M.; Unelius, L.; Sundholm, G.; Hacksell, U.; Johansson, A. M. Derivatives of (R)-1,11-methyleneaporphine: synthesis, structure, and interactions with G-protein coupled receptors. J. Med. Chem. 2000, 43, 1339-1349.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 1339-1349
-
-
Linnanen, T.1
Brisander, M.2
Unelius, L.3
Sundholm, G.4
Hacksell, U.5
Johansson, A.M.6
-
76
-
-
18544373810
-
7 receptor ligands
-
7 receptor ligands. Bioorg. Med. Chem. Lett. 2002, 12, 2451-2454.
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 2451-2454
-
-
Isaac, M.B.1
Xin, T.2
O'Brien, A.3
St-Martin, D.4
Naismith, A.5
MacLean, N.6
Wilson, J.7
Demchyshyn, L.8
Tehim, A.9
Slassi, A.10
-
78
-
-
0035570104
-
7 receptors
-
7 receptors. J. Comput.-Aided Mol. Des. 2001, 15, 883-909.
-
(2001)
J. Comput.-Aided Mol. Des.
, vol.15
, pp. 883-909
-
-
Wilcox, R.E.1
Ragan, J.E.2
Pearlman, R.S.3
Brusniak, M.Y.4
Eglen, R.M.5
Bonhaus, D.W.6
Tenner, T.E.7
Miller, J.D.8
-
79
-
-
0033151286
-
Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes
-
Lawler, C. P.; Prioleau, C.; Lewis, M. M.; Mak, C.; Jiang, D.; Schertz, J. A.; Gonzalez, A. M.; Sibley, D. R.; Mailman, R. B. Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes. Neuropsychopharmacology 1999, 20, 612-627.
-
(1999)
Neuropsychopharmacology
, vol.20
, pp. 612-627
-
-
Lawler, C.P.1
Prioleau, C.2
Lewis, M.M.3
Mak, C.4
Jiang, D.5
Schertz, J.A.6
Gonzalez, A.M.7
Sibley, D.R.8
Mailman, R.B.9
-
82
-
-
0036547431
-
Translational and transcriptional inhibitors block serotonergic phase advances of the suprachiasmatic nucleus circadian pacemaker in vitro
-
Jovanovska, A.; Prosser, R. A. Translational and transcriptional inhibitors block serotonergic phase advances of the suprachiasmatic nucleus circadian pacemaker in vitro. J. Biol. Rhythms 2002, 17, 137-146.
-
(2002)
J. Biol. Rhythms
, vol.17
, pp. 137-146
-
-
Jovanovska, A.1
Prosser, R.A.2
-
83
-
-
0035976631
-
MDMA fenfluramine alter the response of the circadian clock to a serotonin agonist in vitro
-
Biello, S. M.; Dafters, R. I. MDMA and fenfluramine alter the response of the circadian clock to a serotonin agonist in vitro. Brain Res. 2001, 920, 202-209.
-
(2001)
Brain Res.
, vol.920
, pp. 202-209
-
-
Biello, S.M.1
Dafters, R.I.2
-
87
-
-
0035057423
-
Irritable bowel syndrome: New agents targeting serotonin receptor subtypes
-
De Ponti, F. Tonini, M. Irritable bowel syndrome: new agents targeting serotonin receptor subtypes. Drugs 2001, 61, 317-332.
-
(2001)
Drugs
, vol.61
, pp. 317-332
-
-
De Ponti, F.1
Tonini, M.2
-
89
-
-
0030610298
-
7 receptors in the long-lasting hypotensive response induced by 5-hydroxytryptamine in the rat
-
7 receptors in the long-lasting hypotensive response induced by 5-hydroxytryptamine in the rat. Br. J. Pharmacol. 1997, 121, 563-571.
-
(1997)
Br. J. Pharmacol.
, vol.121
, pp. 563-571
-
-
Terron, J.A.1
-
90
-
-
0032993173
-
7 receptor mediating smooth muscle relaxation in canine cerebral arteries
-
7 receptor mediating smooth muscle relaxation in canine cerebral arteries. Br. J. Pharmacol. 1999, 127, 609-616.
-
(1999)
Br. J. Pharmacol.
, vol.127
, pp. 609-616
-
-
Terron, J.A.1
Falcon-Neri, A.2
-
91
-
-
0036035130
-
An introduction to migraine: From ancient treatment to functional pharmacology and antimigraine therapy
-
Villalon, C. M.; Centurion, D.; Valdivia, L. F.; De Vries, P.; Saxena, P. R. An introduction to migraine: From ancient treatment to functional pharmacology and antimigraine therapy. Proc. West. Pharmacol. Soc. 2002, 45, 199-210.
-
(2002)
Proc. West. Pharmacol. Soc.
, vol.45
, pp. 199-210
-
-
Villalon, C.M.1
Centurion, D.2
Valdivia, L.F.3
De Vries, P.4
Saxena, P.R.5
-
92
-
-
0037192581
-
7 receptor involved in the pathogenesis and prophylactic treatment of migraine?
-
7 receptor involved in the pathogenesis and prophylactic treatment of migraine? Eur. J. Pharmacol. 2002, 439, 1-11.
-
(2002)
Eur. J. Pharmacol.
, vol.439
, pp. 1-11
-
-
Terron, J.A.1
-
93
-
-
0037183764
-
7 receptors are involved in mediating 5-HT-induced activation of rat primary afferent neurons
-
7 receptors are involved in mediating 5-HT-induced activation of rat primary afferent neurons. Life Sci. 2002, 71, 2279-2289.
-
(2002)
Life Sci.
, vol.71
, pp. 2279-2289
-
-
Meuser, T.1
Pietruck, C.2
Gabriel, A.3
Xie, G.X.4
Lim, K.J.5
Palmer, P.6
-
94
-
-
0034079914
-
7 receptor
-
7 receptor. Naunyn-Schmiedeberg's Arch. Pharmacol. 2000, 361, 665-671.
-
(2000)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.361
, pp. 665-671
-
-
Villalon, C.M.1
Centurion, D.2
Bravo, G.3
De Vries, P.4
Saxena, P.R.5
Ortiz, M.I.6
-
95
-
-
0030608781
-
7 receptor affinity and protection against sound-induced seizures in DBA/2J mice
-
7 receptor affinity and protection against sound-induced seizures in DBA/2J mice. Naunyn-Schmiedeberg's Arch. Pharmacol. 1997, 356, 820-826.
-
(1997)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.356
, pp. 820-826
-
-
Bourson, A.1
Kapps, V.2
Zwingelstein, C.3
Rudler, A.4
Boess, F.G.5
Sleight, A.J.6
-
96
-
-
0035103867
-
7 receptors in the facilatory response induced by 8-OH-DPAT on learning consolidation
-
7 receptors in the facilatory response induced by 8-OH-DPAT on learning consolidation. Behav. Brain Res. 2001, 121, 21-28.
-
(2001)
Behav. Brain Res.
, vol.121
, pp. 21-28
-
-
Menses, A.1
Terron, J.A.2
-
97
-
-
0036079173
-
SB-258741: A 5-HT7 receptor antagonist of potential clinical interest
-
Pouzet, B. SB-258741: A 5-HT7 receptor antagonist of potential clinical interest. CNS Drug Rev. 2002, 8, 90-100.
-
(2002)
CNS Drug Rev.
, vol.8
, pp. 90-100
-
-
Pouzet, B.1
-
98
-
-
0037472231
-
5-HT4 receptor ligands: Applications and new prospects
-
Langlois, M.; Fischmeister, R. 5-HT4 receptor ligands: Applications and new prospects. J. Med. Chem. 2003, 46, 321-344.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 321-344
-
-
Langlois, M.1
Fischmeister, R.2
-
99
-
-
0037269430
-
5A receptors stably expressed in C6 glioma cells couple to multiple signal transduction pathways
-
5A receptors stably expressed in C6 glioma cells couple to multiple signal transduction pathways. J. Neurochem. 2003, 84, 222-232.
-
(2003)
J. Neurochem.
, vol.84
, pp. 222-232
-
-
Noda, M.1
Yasuda, S.2
Okada, M.3
Higashida, H.4
Shimada, A.5
Iwata, N.6
Ozaki, N.7
Nishikawa, K.8
Shirasawa, S.9
Uchida, M.10
Aoki, S.11
Wada, K.12
-
100
-
-
0038613247
-
6 receptor agonists
-
6 receptor agonists. Drugs Fut. 2002, 27 (Suppl. A), 369.
-
(2002)
Drugs Fut.
, vol.27
, Issue.SUPPL. A
, pp. 369
-
-
Mattsson, C.1
Sandal, A.2
Ludvigsson, E.3
Sonesson, C.4
Bottcher, H.5
-
101
-
-
0343673400
-
7 antagonism
-
7 antagonism. Bioorg. Med. Chem. Lett. 2000, 10, 1097-1100.
-
(2000)
Bioorg. Med. Chem. Lett.
, vol.10
, pp. 1097-1100
-
-
Lopez-Rodriguez, M.L.1
Porras, E.2
Benhamu, B.3
Ramos, J.A.4
Morcillo, M.J.5
Lavandera, J.L.6
|