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Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 20, 2000, Pages 2295-2299

N1-(Benzenesulfonyl)tryptamines as novel 5-HT6 antagonists

(10) Tsai, Yuching a Dukat, Malgorzata a Slassi, Abdelmalik b MacLean, Neil b Demchyshyn, Lidia b Savage, Jason E c Roth, Bryan L c Hufesein, Sandy c Lee, Mase a Glennon, Richard A a

a VIRGINIA COMMONWEALTH UNIVERSITY (United States)

b NPS Allelix Corp (Canada)

c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; N 1 BENZENESULFONYL 5 METHOXY N,N DIMETHYLTRYPTAMINE; SEROTONIN 6 RECEPTOR; SEROTONIN ANTAGONIST; TRYPTAMINE DERIVATIVE; UNCLASSIFIED DRUG; N1 BENZENESULFONYL 5 METHOXY N,N DIMETHYLTRYPTAMINE; N1-BENZENESULFONYL-5-METHOXY-N,N-DIMETHYLTRYPTAMINE; RECOMBINANT PROTEIN; SEROTONIN RECEPTOR;

ACYLATION; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; HUMAN; HUMAN CELL; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFECT; GENETIC TRANSFECTION; KINETICS; METABOLISM; RADIOASSAY; SYNTHESIS;

ADENYLATE CYCLASE; CELL LINE; DRUG DESIGN; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; RADIOLIGAND ASSAY; RECEPTORS, SEROTONIN; RECOMBINANT PROTEINS; SEROTONIN ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; TRYPTAMINES;

EID: 0034675393 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(00)00453-4 Document Type: Article

Times cited : (109)

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