(R)-3,N-Dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1- yl)propyl]benzenesulfonamide: The first selective 5-HT7 receptor antagonist

Journal of Medicinal Chemistry

Volumn 41, Issue 5, 1998, Pages 655-657

  Forbes, I T ^a   Dabbs, S ^a   Duckworth, D M ^a   Jennings, A J ^a   King, F D ^a   Lovell, P J ^a   Brown, A M ^a   Collin, L ^a   Hagan, J J ^a   Middlemiss, D N ^a   Riley, G J ^a   Thomas, D R ^a   Upton, N ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3,N DIMETHYL N [1 METHYL 3 (4 METHYLPIPERIDIN 1 YL)PROPYL]BENZENESULFONAMIDE; BENZENESULFONAMIDE DERIVATIVE; PIPERIDINE DERIVATIVE; RECEPTOR SUBTYPE; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG;

CONTROLLED STUDY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; LETTER; RECEPTOR AFFINITY; STEREOCHEMISTRY;

ADENYLATE CYCLASE; BINDING, COMPETITIVE; CELL LINE; GENE EXPRESSION; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PIPERIDINES; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 18244431670     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970519e     Document Type: Letter

References (23)