SCOPUS 정보 검색 플랫폼

Volumn 43, Issue 3, 2000, Pages 342-345

A novel, potent, and selective 5-HT7 antagonist: (R)-3-(2-(2-(4- methylpiperidin-1-yl)- ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970) [1]

(14) Lovell, Peter J a Bromidge, Steven M a Dabbs, Steven a Duckworth, D Malcolm a Forbes, Ian T a Jennings, Andrew J a King, Frank D a Middlemiss, Derek N a Rahman, Shirley K a Saunders, Damian V a Collin, Lissa L a Hagan, Jim J a Riley, Graham J a Thomas, David R a

a GLAXOSMITHKLINE (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; GUANINE NUCLEOTIDE BINDING PROTEIN; SEROTONIN 7 RECEPTOR; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AUTORADIOGRAPHY; CARBOXY TERMINAL SEQUENCE; DRUG SCREENING; DRUG STRUCTURE; LETTER; LIGAND BINDING; NONHUMAN; RAT; SEQUENCE ANALYSIS;

CELL LINE; HUMANS; MODELS, MOLECULAR; PHENOLS; RADIOLIGAND ASSAY; RECEPTORS, SEROTONIN; RECOMBINANT PROTEINS; SEROTONIN ANTAGONISTS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 0034628555 PISSN: 00222623 EISSN: None Source Type: Journal
DOI: 10.1021/jm991151j Document Type: Letter

Times cited : (242)

References (17)

1
- 18244431670
- 7 receptor antagonist
- 7 Receptor Antagonist. J. Med. Chem. 1998, 41, 655-657.
- (1998) J. Med. Chem. , vol.41 , pp. 655-657
- Forbes, I.T.¹ Dabbs, S.² Duckworth, D.M.³ Jennings, A.J.⁴ King, F.D.⁵ Lovell, P.J.⁶ Collin, L.⁷ Hagan, J.J.⁸ Middlemiss, D.N.⁹ Riley, G.J.¹⁰ Thomas, D.R.¹¹ Upton, N.¹²

2
- 0030612353
- 7 receptor: Orphan found
- 7 receptor: orphan found. Trends Pharmacol. Sci. 1997, 18, 104-107.
- (1997) Trends Pharmacol. Sci. , vol.18 , pp. 104-107
- Eglen, R.M.¹ Jasper, J.R.² Chang, D.J.³ Martin, G.R.⁴

3
- 0027282204
- 7 serotonin receptor subtype
- 7 Serotonin Receptor Subtype. J. Biol. Chem. 1993, 268, 18200-18204.
- (1993) J. Biol. Chem. , vol.268 , pp. 18200-18204
- Shen, Y.¹ Monsma, F.J.² Metcalf, M.A.³ Jose, P.A.⁴ Hamblin, M.W.⁵ Sibley, D.R.⁶

4
- 0027368668
- 7) implicated in the regulation of mammalian circadian rhythms
- 7) Implicated in the Regulation of Mammalian Circadian Rhythms. Neuron 1993, 11, 449-458.
- (1993) Neuron , vol.11 , pp. 449-458
- Lovenberg, T.W.¹ Baron, B.M.² De Lecea, L.³ Miller, J.O.⁴ Prosser, R.A.⁵ Rea, M.A.⁶ Foye, P.E.⁷ Rucke, M.⁸ Slone, A.L.⁹ Siegel, B.W.¹⁰ Danielson, P.E.¹¹ Sutcliffe, J.G.¹² Erlander, M.G.¹³

5
- 0027183389
- 7) activating cAMP formation
- 7) Activating cAMP Formation. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 8547-8551.
- (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 8547-8551
- Ruat, M.¹ Traiffort, E.² Leurs, R.³ Tardivel-Lacombe, J.⁴ Diaz, J.⁵ Arrang, J.-M.⁶ Schwartz, J.-C.⁷

6
- 0027186438
- Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase
- Plassat, J.-L.; Amlaiky, N.; Hen, R. Molecular Cloning of a Mammalian Serotonin Receptor that Activates Adenylate Cyclase. Mol. Pharmacol. 1993, 44, 229-236.
- (1993) Mol. Pharmacol. , vol.44 , pp. 229-236
- Plassat, J.-L.¹ Amlaiky, N.² Hen, R.³

7
- 0028168584
- 7 receptor positively coupled to adenylyl cyclase
- 7 Receptor Positively Coupled to Adenylyl Cyclase. J. Neurochem. 1994, 63, 456-464.
- (1994) J. Neurochem. , vol.63 , pp. 456-464
- Tsou, A.-P.¹ Kosaka, A.² Bach, C.³ Zuppan, P.⁴ Yee, C.⁵ Tom, L.⁶ Alvarez, R.⁷ Ramsey, S.⁸ Bonhaus, D.W.⁹ Stefanich, E.¹⁰ Jakeman, L.¹¹ Eglen, R.M.¹² Chan, H.W.¹³

8
- 0027421620
- 7) positively coupled to adenylate cyclase
- 7) Positively Coupled to Adenylate Cyclase. J. Biol. Chem. 1993, 268, 23422-23426.
- (1993) J. Biol. Chem. , vol.268 , pp. 23422-23426
- Bard, J.A.¹ Zgombick, J.² Adham, N.³ Vaysse, P.⁴ Branchek, T.A.⁵ Weinshank, R.L.⁶

9
- 0029012193
- 7 receptors in guinea pig brain
- 7 Receptors in Guinea Pig Brain. Br. J. Pharmacol. 1995, 115, 107-116.
- (1995) Br. J. Pharmacol. , vol.115 , pp. 107-116
- To, Z.P.¹ Bonhaus, D.W.² Eglen, R.M.³ Jakeman, L.B.⁴

10
- 0002133977
- 7 receptor and its mRNA in rat CNS by radioligand binding and in situ hybridisation
- 7 Receptor and its mRNA in Rat CNS by Radioligand Binding and In Situ Hybridisation. Br. J. Pharmacol. 1994, 112, 100P.
- (1994) Br. J. Pharmacol. , vol.112
- Branchek, T.A.¹ Gustafson, E.L.² Durkin, M.M.³ Bard, J.A.⁴ Weinshank, R.L.⁵

11
- 0029961692
- 7 receptor in rat brain
- 7 Receptor in Rat Brain. Br. J. Pharmacol. 1996, 117, 657-666.
- (1996) Br. J. Pharmacol. , vol.117 , pp. 657-666
- Gustafson, E.L.¹ Durkin, M.M.² Bard, J.A.³ Zgombick, J.⁴ Branchek, T.A.⁵

12
- 0027345403
- A clinician's primer on the circadian clock: Its localization, function and resetting
- Schwartz, W. J. A Clinician's Primer on the Circadian Clock: Its Localization, Function and Resetting. Adv. Int. Med. 1993, 38, 81-106.
- (1993) Adv. Int. Med. , vol.38 , pp. 81-106
- Schwartz, W.J.¹

13
- 0033602216
- 7 receptor
- 7 Receptor. J. Med. Chem. 1999, 42, 533-535.
- (1999) J. Med. Chem. , vol.42 , pp. 533-535
- Kikuchi, C.¹ Nagaso, H.² Hiranuma, T.³ Koyama, M.⁴

14
- 84986437005
- Macromodel-an integrated software system for modelling organic and bioorganic molecules using molecular mechanics
- Mohamadi, F.; Richards, N. G. J.; Guida, W. C.; Liskamp, R.; Lipton, M.; Caufield, C.; Chang, G.; Hendrickson, T.; Still, W. C. MacroModel-An Integrated Software System for Modelling Organic and Bioorganic Molecules using Molecular Mechanics. J. Comput. Chem. 1990, 11, 440.
- (1990) J. Comput. Chem. , vol.11 , pp. 440
- Mohamadi, F.¹ Richards, N.G.J.² Guida, W.C.³ Liskamp, R.⁴ Lipton, M.⁵ Caufield, C.⁶ Chang, G.⁷ Hendrickson, T.⁸ Still, W.C.⁹

15
- 0031565726
- An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors
- Baldwin, J. M.; Schertler, G. F. X.; Unger, V. M. An Alpha-carbon Template for the Transmembrane Helices in the Rhodopsin Family of G-Protein-coupled Receptors. J. Mol. Biol. 1997, 272, 144-164.
- (1997) J. Mol. Biol. , vol.272 , pp. 144-164
- Baldwin, J.M.¹ Schertler, G.F.X.² Unger, V.M.³

16
- 0343572579
- Complementary enantioselective approaches to quinolizidine alkaloids
- Knight, D. W.; Morley, C.; Share, A. C. Complementary Enantioselective approaches to quinolizidine alkaloids. J. Chem. Soc., Perkin Trans, 1 1994, 2904.
- (1994) J. Chem. Soc., Perkin Trans, 1 , pp. 2904
- Knight, D.W.¹ Morley, C.² Share, A.C.³

17
- 15144342436
- 7 receptor (long form); antagonist profile of SB-258719
- 7 receptor (long form); antagonist profile of SB-258719. Br. J. Pharmacol. 1998, 124, 1300-1306.
- (1998) Br. J. Pharmacol. , vol.124 , pp. 1300-1306
- Thomas, D.R.¹ Gittins, S.A.² Collin, L.L.³ Middlemiss, D.N.⁴ Riley, G.J.⁵ Hagan, J.J.⁶ Gloger, I.⁷ Ellis, C.E.⁸ Forbes, I.T.⁹ Brown, A.M.¹⁰

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.